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Science News Archive June 2004 - Page 6


Page 6 of 12

Imaging the healing heart

Researchers developed a non-invasive imaging method to track new blood vessel growth in the heart after a heart attack. The technique uses a radioactively labeled protein to detect changes in damaged areas over time, providing clear visualization of healing processes.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 15, 2004

JCI table of contents, 15 June 2004

Researchers at Brigham and Women's Hospital have developed a strategy using small interfering RNA to enhance cancer treatment in cases of drug resistance. They tested their theory in a form of leukemia that is resistant to commonly used anti-cancer drugs.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 15, 2004

Geologists map Cartwright country

Researchers at Washington University in St. Louis have created a detailed map of the Comstock Lode, a 14-million-year-old gold and silver ore deposit. The map uses mathematical techniques to visualize patterns of oxygen isotope exchange between water and rock, providing insights into the geological processes that formed the ore district.

Ecology drives the worldwide distribution of human diseases

Researchers found that climatic factors are the most important determinant of human pathogen distribution, contradicting conventional assumptions about disease control. Understanding ecological links between disease and environment could inform effective preventive strategies.

SourcePLOS·JournalPLOS Biology·DateJun 15, 2004

Treatment blocks progression of diabetes in mice

A new treatment approach has been developed to prevent autoimmune diabetes in mice by blocking the interaction between NKG2D on T cells and proteins found on abnormal cells. This breakthrough finding suggests a potential therapeutic strategy for preventing or controlling type 1 diabetes.

SourceCell Press·JournalImmunity·DateJun 15, 2004

Gray matters

Researchers at the University of Southern California challenge the 'arithmetic' neurons use to process information, finding that summation depends on input location. The study reveals a two-layer model of processing, with local thresholds in separate branches and linear summation at the cell body.

SourceUniversity of Southern California·JournalNature Neuroscience·DateJun 15, 2004

Turning bone into nerve

Researchers successfully induced neuronal cells from bone marrow stromal cells, offering a potential treatment option for neurological disorders. The findings have significant implications for the development of regenerative medicine techniques.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 15, 2004

Small RNA surmounts large cancer problem

Researchers discovered that stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin. This finding suggests a new approach for treating cancer by targeting specific genes.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 15, 2004

A protein's role in progressive renal disease

Researchers investigate the role of mutated a-actinin-4 in FSGS, a leading cause of progressive kidney failure. The study reveals two possible mechanisms: aggregation and rapid degradation, which can injure kidney cells, highlighting potential therapeutic targets.

SourcePLOS·JournalPLOS Biology·DateJun 15, 2004

Quantum dots see in the dark

Researchers at USC and UT Austin have developed a device based on quantum dots that can detect infrared radiation in a crucial wavelength range. This technology has the potential to improve night vision goggles, medical sensors and environmental monitors.

SourceUniversity of Southern California·JournalApplied Physics Letters·DateJun 14, 2004

Post-surgical pain may be age related

A study of over 200 patients with hernia found that post-surgical pain was inversely related to age, with younger patients experiencing less pain. Laparoscopic repair was also associated with lower first-day pain scores and faster return to normal activities compared to open surgery.

SourceJAMA Network·JournalArchives of Surgery·DateJun 14, 2004

How genes get us wired

Researchers discovered that the Hoxb1 gene is necessary for forming a circuit between the brain and facial muscles, controlling movements such as blinking and facial expressions. The study's findings have implications for understanding and potentially treating Mobius syndrome and other nerve-related disorders.

SourceUniversity of Utah Health·JournalGenes & Development·DateJun 14, 2004

Listerine antiseptic proven as effective as dental floss

A long-term study published in JADA demonstrates that rinsing twice daily with Listerine Antiseptic mouthrinse is as effective at reducing plaque and gingivitis as flossing once daily. The study found that Listerine Antiseptic reduced plaque by 20% and gingivitis by 11%, while flossing led to 3.4% and 4.3% reductions respectively.

SourceKetchum UK·JournalThe Journal of the American Dental Association·DateJun 14, 2004

Ecosystem bounces back from hurricanes

A team of scientists found that the estuaries were resilient and recovered quickly from the storms, with most shellfish and finfish populations returning to normal. However, blue crabs took longer to recover due to overfishing and floodwaters disrupting their migration patterns.

SourceNorth Carolina State University·JournalProceedings of the National Academy of Sciences·DateJun 14, 2004

VELCADE(TM) data confirms long-term survival

A new study shows that VELCADE (bortezomib) can significantly extend survival and induce important responses in relapsed and refractory multiple myeloma patients. The median overall survival was 17.2 months, with a 14.1-month duration of response and 15.3-month time to disease progression.