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Science News Archive February 2005 - Page 6


Page 6 of 13

JCI table of contents March 1, 2005

Researchers uncover how alpha-defensin-1 inhibits HIV infection in CD4+ T cells and how lubricin protects cartilage surfaces. These findings provide insights into innate immunity against HIV and may lead to the development of defensin-like drugs for prevention and treatment.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateFeb 17, 2005

Mechanical tension helps shape lung development

Research by Ingber and colleagues found that manipulating mechanical force in developing mouse lungs can slow down or speed up growth, which could lead to novel treatments for lung conditions. This study sheds light on the importance of mechanobiology in understanding normal lung development and potential intervention pathways.

SourceBoston Children's Hospital·JournalDevelopmental Dynamics·DateFeb 17, 2005

Defensins ward off HIV in two ways

Researchers found that alpha-defensin-1 directly inactivates HIV when serum levels are low, while also acting on vulnerable cells to block infection. The study provides a basis for developing defensin-like drugs to prevent and treat HIV.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateFeb 17, 2005

Small is different

Computer simulations have revealed that gold is an effective catalyst when it's in clusters of eight to two dozen atoms, and electrical charging plays a crucial role. This breakthrough has opened up new avenues for exploring environmental effects on catalysis.

Brain activity of men and women during hostile or impulsive acts differs less on nicotine

A recent study found that nicotine can eliminate the differences in brain activity between men and women during hostile or impulsive acts. Brain imaging research conducted by UCI showed that when participants were given nicotine, the brain-metabolism activity was virtually identical for both sexes.

SourceUniversity of California - Irvine·JournalThe International Journal of Neuropsychopharmacology·DateFeb 17, 2005

Worms, slugs inspire robotic devices

Researchers have developed two novel robotic devices inspired by the movement of worms and slugs, including an endoscopic device that can navigate complex spaces and a gripping device that can pick up soft objects without damaging them. The devices aim to reduce discomfort and increase compliance during medical procedures.

Brain center shows there is accounting for taste

Researchers found that brain center's neurons encoded learning associated with taste stimuli, revealing different circuitry for processing rewarding and aversive stimuli. The study supports the idea that individual NAc neurons play a role in aversion and Pavlovian learning.

SourceCell Press·JournalNeuron·DateFeb 16, 2005

New software helps with anti-terrorism planning

A new software developed for the U.S. Marine Corps helps organizations prioritize resources and allocate funds to protect critical infrastructure from terrorist attacks. The system considers factors such as protecting people, mission importance, and acceptable risks.

SourcePenn State·JournalJournal of the American Society for Information Science and Technology·DateFeb 16, 2005

Genomics champion Eric Lander receives 2004 AAAS Public Understanding of Science & Technology Award

Eric Lander, a prominent genomics researcher, has been recognized by the American Association for the Advancement of Science (AAAS) for his ability to communicate complex scientific concepts to the public. He is credited with helping to educate the public about the Human Genome Project and its implications for society.

Immediate access to antibiotics stems spread of sexually transmitted diseases

A study led by Hopkins researchers found that providing packets of antibiotics or mailing medication directly to partners significantly reduced re-infections with gonorrhea and Chlamydia. The expedited approach resulted in a 68% decrease in re-infections with gonorrhea and an 18% decrease overall, when results for both diseases were co...

SourceJohns Hopkins Medicine·JournalNew England Journal of Medicine·DateFeb 16, 2005

Educators in Pennsylvania and North Carolina earn top 2004 Mentoring Awards from AAAS

Rhonda Hughes, a mathematics professor at Bryn Mawr College in Pennsylvania, has mentored 57 women and minority students to earn graduate degrees in mathematics. Jagannathan Sankar, Professor of Mechanical and Chemical Engineering at North Carolina A&T State University, facilitated the mentorship of 46 Ph.D. students, including 22 unde...

Computer-aided protein design wins prestigious AAAS Newcomb Cleveland Prize

A team of researchers from Howard Hughes Medical Institute and the University of Washington designed a novel protein with atomic-level accuracy using computer-aided design. The breakthrough allows for the exploration of previously unseen regions of the protein universe, opening up new possibilities for studying protein-folding energetics.

The oldest Homo sapiens

The oldest known fossils of Homo sapiens have been found in Ethiopia and date back to 195,000 years ago. This pushes the emergence of anatomically modern humans back by approximately 30,000 years, with implications for our understanding of human cultural development.

SourceUniversity of Utah·JournalNature·DateFeb 16, 2005