Researchers have uncovered structural features of the brain that may contribute to the development of ADHD. The study used a new analysis tool to examine shape differences in the brains of children with ADHD and found significant abnormalities in boys, but not girls.
Researchers at the University of Utah are enrolling patients in a clinical trial using their own bone marrow cells to regenerate heart muscle and improve blood flow. The study aims to improve heart function and quality of life for those with congestive heart failure.
A new microarray analysis technique improved prenatal diagnosis for detecting chromosomal abnormalities in 300 cases at Baylor College of Medicine. The test identified 58 copy number variations, including 15 significant findings that would have been missed otherwise.
A new forecasting method predicts a significant rise in demand for anti-malarial treatments due to the loss of effectiveness of current medications. The method aims to ensure an adequate supply of effective drugs by accurately predicting future demand, particularly in Africa where malaria affects millions.
A new study published in PLoS Biology found that ants specializing in specific jobs are not more efficient than 'generalist' ants, challenging the idea that job specialization contributes to their success. The research tested individual ants performing various tasks and found that specialists put in more hours of work but did not outpe...
A team of researchers argues that the success of ACT in curing malaria demands a new approach to assessing new antimalarial drugs. The authors discuss the design and interpretation of clinical trials for new antimalarial drugs, emphasizing the need for improved efficacy and public health utility.
A team led by Craig Pikaard discovered a new mechanism by which plant cells silence potentially harmful genes, involving the non-coding region of DNA and two plant-specific RNA polymerases. The research has major implications for gene therapy, where RNA-centric approaches show promise for controlling diseases such as cancer and HIV.
The paper 'CEVITATM: the valuation and reporting of strategic capabilities' by Janek Ratnatunga, Norman Gray, and Kashi R. Balachandran has been awarded the Management Accounting Section (MAS) Greatest Potential Impact on Practice Award for its potential to bridge the gap between academic research and professional management accounting...
A new study by UC Davis researchers suggests that drops in blood oxygen levels may contribute to sudden unexpected death in epilepsy (SUDEP) patients. Seizures in the temporal lobe and low oxygen levels during episodes are more common in males than females.
A new study published in Nature Geoscience reveals the devastating impact of increased nitrogen deposition on Slovakian soil acidity, compromising plant fertility and surface water quality. Researchers warn that many soils are already susceptible to this process due to decades of human-influenced pollution.
Researchers have created a new model to calculate how much CO2 can be stored safely in geological formations, with potential applications for large-scale carbon sequestration projects. The tool predicts the migration of CO2 plumes and can help policymakers make informed decisions about storage sites.
A recent study found that patients from higher-income and more educated communities are more likely to undergo immediate breast reconstruction after mastectomy. The research highlights the importance of community demographics in influencing access to this life-changing procedure.
A University of Alberta researcher has developed guidelines to prevent genetic research from awakening racist attitudes. The study emphasizes the importance of proper group representation and justifying research focus on specific ethnic groups.
A new study identifies a genetic pathway that determines the pattern of flower growth in tomato plants. The researchers found that manipulation of this pathway can turn a single stem into hundreds of branch-bearing shoots, increasing crop yields.
A longitudinal study of 540 adults found that approximately one third of Canadians with physician-diagnosed asthma do not have asthma when objectively tested. Obesity is linked to increased asthma rates in North America, but overdiagnosis may be more common than previously thought, particularly among obese adults.
Scientists have discovered a new clue for understanding how misfolded proteins cause cell death in Huntington's disease. The study found that polyQ-expanded proteins interact with and trap other proteins, leading to a breakdown in protein quality control, which may contribute to the disease's toxicity.
Researchers found that immune cells known as killer T cells recruit other accessory cells to drive the disease, causing blood vessel damage. This discovery offers a new avenue for possible treatments for deadly meningitis.
A study by Associate Professor Katherine Samaras reveals that HIV treatment causes inflammation, leading to increased cardiac and metabolic risk. Patients with HIV-infection tend to gain weight around their abdomen, increasing their risk of heart disease and diabetes.
A large-scale clinical trial found no significant protection against cancer from long-term vitamin E or C supplements. Researchers followed over 14,000 physicians for up to 10 years without detecting a link between these supplements and reduced cancer rates.
The article reveals substantial inequalities in healthy life years (HLYs) from the age of 50 across EU countries, with GDP and spending on elderly care being key factors. HLYs at 50 are highest in Denmark and Malta for men, and France, Italy, and Spain for women, while lowest in Estonia and Hungary.
Researchers found that men taking aspirin had significantly lower PSA levels, especially among those with prostate cancer. However, this may affect the ability to detect early-stage prostate cancer through PSA screening.
Researchers found that DFMO treatment reduced dysplasia progression in patients with Barrett's esophagus, while also lowering putrescine levels and KLF5 expression. The study suggests a potential mechanism for the chemopreventive effects of DFMO.
New research reveals FoxJ1 helps create left-right asymmetry by orchestrating the formation of nodal cilia, which generate fluid flow to orient tissues. The study finds that increasing FoxJ1 levels leads to the formation of ectopic cilia, challenging current theories on its role.
A University of New South Wales researcher calls for a more flexible approach to vaccine funding, considering quality-of-life impacts. This could lead to improved productivity, reduced sick leave for parents, and enhanced herd immunity against diseases such as chickenpox and shingles.
A study found that cocaine-addicted individuals prefer drug-related images over neutral ones, challenging the assumption that pleasure drives drug choice. The tasks developed in this research can help clinicians monitor choice behavior in addicted individuals, potentially predicting treatment effectiveness and outcomes.
A large clinical trial found that calcium supplementation reduced colorectal adenoma recurrence risk by 32% only in those with low magnesium to calcium ratio. This suggests a personalized diet/supplementation regimen considering both nutrients may be more effective than supplementing with one alone.
Comet particles from Wild 2 provide a glimpse of the solar system's early convulsions, flinging primordial material out into the cold regions. The particles contain minerals formed at high temperatures, suggesting transport from the inner to outer solar system.
Researchers at Northwestern University's Feinberg School of Medicine discovered that super-aged brains have a lower number of fiber-like tangles, which accumulate inside brain cells and are thought to kill them. This finding suggests that individuals with fewer tangles perform better cognitively.
A team of Boston College and MIT scientists has discovered a new class of exceptionally effective catalysts that promote the powerful olefin metathesis reaction, opening up a vast new scientific platform. The new catalysts provide unprecedented control and selectivity for complex chemical reactions.
Scientists have identified new species of bacteria that can grow at low temperatures and spoil raw milk even when refrigerated. The discovery highlights the complex microbial population of raw milk and underscores the importance of developing tools to monitor cold-tolerant bacteria.
Glioblastoma cells release exosomes containing RNA and proteins that promote tumor growth, but also carry data that can be used to guide targeted therapy. The study identified factors in these exosomes that could be used as biomarkers to monitor treatment response.
Research finds that PEA-15 protein forces ovarian cancer cells to eat themselves, leading to increased median survival time. High levels of PEA-15 are linked to improved patient outcomes and may offer a new dimension for targeting ERK in cancer therapy.
Children with social and academic problems in elementary school are more likely to engage in serious violent behavior later, due to parents withdrawing supervision and friends with deviant behavior. Successful early intervention can redirect paths of antisocial development to prevent violent behavior.
Scientists discovered a key step in HIV's attack on brain cells and were able to reverse its effects by blocking the receptor. The discovery opens up a new avenue for researchers to explore in preventing or treating HIV's neurological effects, which have no currently approved treatment.
John O'Keefe received the Gruber Foundation Neuroscience Prize for his groundbreaking 'place cell' research, which enabled animals to map and remember locations. His work has influenced recent studies on memory loss and Alzheimer's disease.
A recent discovery in Ethiopia's Gona region has challenged previous estimates of Homo erectus infant head size, indicating a possible increase in brain capacity. The findings, published in Science, suggest that the ancient human ancestor may have been born with brains comparable to those of modern humans.
Researchers point to historical events like the collapse of the City of Glasgow Bank in 1878 as a guide for addressing current banking crises. The UK's Financial Services Authority is recruiting more staff and considering stricter regulation, with experts emphasizing the need for effective policing of new regulations.
A study of gibbon foot movements suggests that early humans may have used elastic energy storage mechanisms to walk efficiently. The gibbon's flexible foot allows for more efficient energy storage and release, similar to the human foot.
Researchers at LSU Health Sciences Center have identified microRNA-146a as a crucial regulator of inflammation and disease-related neuropathology in Alzheimer's disease. The study found that miRNA-146a targets the messenger RNA of an anti-inflammatory regulator, promoting brain cell inflammation.
A $1.7 million study will investigate how the body metabolizes ecstasy, a 'hug drug' with serious negative effects on brain function. The research aims to identify individuals at risk of long-term adverse effects from the drug.
A longitudinal study found that characteristics in four social environments—families, peers, schools, and neighborhoods—contribute to adolescent alcohol misuse. The study highlights the importance of examining connections between all social environments and suggests a more inclusive view of adolescent social worlds.
Researchers at the University of Iowa have developed a method to estimate photosynthetic uptake by plants over large regions, improving accuracy of global warming and land cover change estimates. By analyzing carbonyl sulfide levels, scientists can quantify human-generated CO2 emissions and develop better management strategies.
Astronauts on the International Space Station successfully performed remotely-guided sonograms using a ground-to-space communication system. The study's findings demonstrate the feasibility of sonography in microgravity environments and could lead to new applications in space medicine.
A new study found that children distressed by family fighting have higher cortisol levels, a stress hormone. This increase in cortisol may explain why children experiencing high levels of distress during parental conflicts are more likely to develop psychological problems.
Researchers at Harvard University have demonstrated that metal nanoparticles in a periodic array can exhibit narrower spectral widths, improving the sensitivity of detecting molecules at low concentrations. By optimizing electromagnetic interactions between particles, the method can enhance spectroscopy and biosensors.
A new study found that children's stress hormone cortisol levels increase from morning to afternoon in full-day child care, depending on the quality of their relationship with caregivers. Children with more clingy or conflicted relationships with teachers showed greater rises in cortisol.
Columbia University Irving Medical Center honors Dr. Bruce Spiegelman with the Naomi Berrie Award for his groundbreaking work on metabolic pathways of obesity and diabetes research. Dr. Spiegelman's discoveries have identified key molecules critical in fat cell differentiation, insulin resistance, and energy expenditure. Meanwhile, jun...
Research found that childhood experiences can lead to minor behavior problems, which grow into violent acts in teens. Successful interventions like parent training and social skills training can redirect these paths.
Physicists at UCL and the London Centre for Nanotechnology have made a significant discovery in quantum computing, extending the quantum lifetime of electrons by over 5,000%. This achievement brings researchers closer to building a usable quantum computer. The study used a powerful magnetic field to align electron spins, providing a cr...
Arbor Vita Corporation presented new data on its rapid, point-of-care prototype HPV test with a high positive predictive value for cervical cancer and pre-cancer detection. The test detects the E6 oncoprotein produced by human papillomavirus (HPV), which is a diagnostic marker of high positive predictive value.
Researchers at WashU Medicine developed a gene chip technology to detect pneumonia in ICU patients on ventilators, identifying 52 cases in a large-scale study. The technology uses a 85-gene riboleukogram to monitor changes in immune response before clinical symptoms develop.
A new study by University of Maryland sociologists finds that unhappy people watch significantly more TV than very happy individuals, who prefer reading and socializing. The study analyzed 30 years of national data and found that TV viewing can provide short-term pleasure but has less positive effects in the long run.
Researchers have discovered a previously unknown cell pathway that drives a lethal subtype of breast cancer, disproportionately affecting African American women. The study may lead to the development of new targeted therapies for this aggressive cancer type.
A new program, REDI Head Start, combines pre-reading skills with social-emotional learning to foster preschoolers' academic and social success. Children in the REDI program outperformed those in traditional programs on tests of emotional development, impulsivity, aggression, and reading skills.
A new imaging database of chick embryos will map gene expression during the first 10 days of development, providing insights into diseases like spina bifida and cancer. The £2.6 million initiative aims to understand why developmental problems occur.
Human factors researchers suggest adding engine noise to quiet hybrid cars to improve pedestrian safety. Participants rated automotive engine sounds as the most preferred category, followed by white noise and hum.
The Neuroscience Information Framework (NIF) is a dynamic inventory of web-based neurosciences data, resources, and tools. The NIF enables discovery and access to public research data and tools worldwide through an open source, networked environment.
A longitudinal study found that frequent moves during 2nd to 5th grade can lead to declines in academic performance and classroom participation. However, having a supportive teacher who encourages peer acceptance can help children make a smooth transition. The study suggests that teachers play a critical role in mitigating the negative...
Researchers identified two genes that sensitize lymphoid progenitor cells to the effects of aging and confer resistance to leukemogenesis. These genes regulate cell cycle progression and mediate senescence and tumor suppression in aged cells.
A research-based program, REDI, was found to improve both academic and social-emotional areas in children participating in Head Start. The study, published in Child Development, showed that REDI's dual-focus approach effectively promoted gains in vocabulary, pre-reading skills, emotional understanding, and social competence.