A study using the MEADERS (Medication Error and Adverse Drug Event Reporting System) system found that communication problems and lack of knowledge are leading causes of medication errors, with cardiovascular medications being the most commonly associated. The system has been successful in reducing harm to patients, documenting 11% of ...
The Cone Beam Computed Tomography (CBCT) scanner provides high-quality images without compressing the breast tissue, making it a promising supporting role to conventional mammography. Preliminary research shows that breast coverage and radiation dose are comparable to mammography.
Researchers discover JavaScript code accessing browser histories without user consent, highlighting potential for malicious activities such as phishing. Latest browsers have patched vulnerabilities, but users on outdated versions remain at risk.
Scientists in Mexico and the US have synthesized gold and silver nanoparticles just 25 nanometers in diameter, which could have potential applications as catalysts, drug-delivery agents, and quantum dots. The analysis reveals multiple layers of shells within each particle, with some blending or alloying of metals.
A study found that decreased physician reimbursement for hormone therapy reduced its use in low-risk prostate cancer cases by 40%. However, AST usage remained unchanged in patients with metastatic disease. The decrease is attributed to the real effect of reimbursement change.
The ImREAL project aims to create a simulated learning environment that responds to users' behavior and adapts accordingly. Researchers will develop intelligent tools to encourage trainees to detect subtle differences in communication and social cues across cultures.
The US Department of Health and Human Services has set ambitious targets to improve breastfeeding rates in the country. The Healthy People 2020 goals aim to increase the percentage of Baby Friendly Hospitals and workplaces that accommodate working mothers, as well as reduce formula supplementation during maternity hospital stays.
A study by Washington University School of Medicine reveals that genes alone do not predict disease risk, as environment interacts with DNA in complex ways. The research found that genetic variants have different effects in different environments, making it challenging to make accurate predictions.
Recent AGU research highlights increased flood fatalities in Africa due to population trends, not climate change, as well as lake warming caused by climate change. The study also found that the ozone hole affects upper-atmosphere temperature and circulation, while solar wind contains more oxygen than previously thought.
A faulty MAP3K1 gene has been identified as a cause of disorders of sex development (DSD) in male embryos, leading to genital abnormalities and feminine appearance.
A recent study by chemists from University of Copenhagen and NASA found that anesthetic gases have a significant impact on the climate. One kilo of anaesthetic gas affects the climate as much as 1620 kilos of CO2, with three commonly used gasses having global warming potentials ranging from 210 to 1620 times that of CO2.
Onconova Therapeutics presents updated clinical trial results for Estybon (ON 01910.Na) in patients with myelodysplastic syndromes, showing increases in overall survival and bone marrow blast responses. Additionally, ON 013105, a Cyclin D1 inhibitor, demonstrates efficacy in nonclinical models of mantle cell lymphoma.
A $7 million grant from the Bill & Melinda Gates Foundation will support a four-year research project to develop clinical guidelines for pre-eclampsia diagnosis and treatment in lower- and middle-income countries. The project aims to reduce maternal, fetal, and newborn deaths related to pre-eclampsia.
New research in Psychological Science found that the fear of being the target of malicious envy motivates people to act more helpfully toward those they think might be jealous. This fear encourages prosocial behavior, such as sharing resources with others.
A review of 134 studies on breast reconstruction found inconsistent reporting and a lack of standardization in outcome assessment. The authors highlight the need for non-clinical factors such as patient-reported outcomes to be incorporated into outcome assessment.
Researchers found that dynamic Hsp27 regulation is crucial for clearing abnormal tau protein and preventing neurofibrillary tangles. Effective Hsp27 switching promotes tau recycling in healthy nerve cells and clears brain abnormalities.
Researchers model how Neolithic transition was halted by population density of hunter-gatherers. The findings confirm archeological data that challenge the assumption of climate adaptation as a primary factor.
New research suggests that exposure to nicotine during pregnancy can lead to a decrease in adult stem cells and alter synaptic plasticity in the hippocampus, increasing the risk of behavioral problems such as ADHD. The findings may provide a brain-circuitry mechanism for learning disabilities in children born to smoking mothers.
Researchers at VCU Massey Cancer Center discovered a previously unknown mechanism in NSCLC cells that contributes to their ability to maintain and grow tumors. The study found that a protein factor regulates the expression of caspase-9, a main player in apoptosis, which could provide a new target for therapies.
The new report presents a statistical overview of the U.S. doctoral education system, showcasing trends and changes in the number of international students pursuing a doctorate at U.S. universities. The report aims to inform improvements in the U.S. doctoral education system, emphasizing the need to revitalize America's STEM pipeline.
Researchers developed a new high-performance fiber with superior strength and toughness, surpassing Kevlar. The fiber was created by combining carbon nanotubes with a polymer and testing its properties using in-situ electron microscopy.
Phase III trials should aim to find clinically important differences in survival outcomes, rather than just statistically significant ones. Pharmaceutical companies often prioritize minimal but detectable differences that are feasible within trial constraints.
Scientists are using Alvin and Sentry to explore the ocean floor in the Gulf of Mexico, searching for signs of impact from the 2010 oil spill. The expedition aims to map the seafloor, collect samples, and document the effects on deep-ocean communities.
Researchers have characterized a series of bismuth citrate complexes and modeled the structure of ranitidine bismuth citrate, a medicine used to treat peptic ulcers and gastric reflux disease. The polymeric framework may serve as a 'drug carrier' for delivering other drugs in the human body.
Researchers at UT Southwestern Medical Center have identified the molecular mechanisms underlying antiphospholipid syndrome (APS), a potentially life-threatening condition that causes blood clots. The study's findings suggest that targeting specific proteins may lead to new therapies for APS and its associated pregnancy complications.
A recent UC Riverside study evaluated five e-cigarette brands, revealing design flaws, inadequate labeling, and quality control concerns. The researchers urge regulators to remove e-cigarettes from the market until their safety is adequately evaluated.
The study used an extensional rheometer to measure flow properties of complex fluids, revealing intriguing effects depending on concentration and velocity. At high speeds, the fluid can fracture like a solid, behaving like a jammed system with clusters locking together.
A recent study found that nearly half of youth with type 1 and type 2 diabetes are current smokers, increasing their risk for heart disease. Aggressive smoking prevention and cessation programs are needed to prevent or delay heart disease in this population.
The Mental Health Research Network aims to make research faster, less expensive, and more relevant to real-world healthcare. By analyzing data from 10 million people in 12 states, researchers hope to find effective methods for detecting, treating, and preventing mental disorders.
The study identifies the early Katian Age as the commencement of the Kwangsian Orogeny, a significant event in South China's geological evolution. Continuous Ordovician sections in Yongxin and Chongyi Counties display a continuous graptolite sequence, indicating a sharp facies change from deep-water black shales to shallow-water clastics.
The new infrared camera features a 16-fold increase in pixels, enabling higher-resolution images in the dark. The Type-II superlattice technology reduces mercury content and improves uniformity, increasing yield and reducing cost.
Researchers develop system to analyze patient data, therapist interactions, for better understanding of depression causes and prevention strategies. The approach balances individual differences with observed similarities in behavior and response to treatment.
Scientists studied ice cores to find evidence of biomass burning fluctuations in Southern Hemisphere. Biomass burning trends differ from Northern Hemisphere records, suggesting changes for climate models.
A study by Dini et al. investigates the effect of 6 mT Static Magnetic Field (SMF) on phagocytosis in human macrophages, finding that it depends on the degree of macrophage differentiation. The results suggest that moderate intensity SMF can modify cell surface morphology and influence fluid-phase endocytosis and phagocytosis.
A team of researchers has made significant strides in understanding the long-term history of El Niño, a global climate phenomenon that impacts much of the world. By reconstructing sea surface temperatures over the past 14,000 years, the study provides valuable insights into the dynamics of this complex system.
A new technology uses metabolic imaging to rapidly assess prostate tumor presence and aggressiveness in real-time. The initial results validate preclinical research linking tumor metabolism speed to growth aggressiveness.
Researchers from Universidad Pablo de Olavide and Universidad de Sevilla have found patterns of behavior before an earthquake occur on the Iberian peninsula. The team used clustering techniques to forecast medium-large seismic movements with a sensitivity rate of 90%.
Researchers present a comprehensive model of Type Ia supernovae (SNe Ia) progenitors using the Single Degenerate (SD) framework. The study confirms that the model describes potential progenitor systems of SNe Ia, including cases like Case Wind and Case Calm.
Rice University researchers found that adding tiny amounts of ozone to single-walled carbon nanotubes decorates them with oxygen atoms, enhancing their near-infrared fluorescence intensity and shifting the wavelength. The process is simple enough for a physical chemist to do, and lab tests showed stable fluorescent properties for months.
Researchers at the University of Cambridge found that brain disruptions cause confusion between memories, leading to false remembering. This insight could lead to new treatments reducing memory confusion and improving daily functioning for patients.
Nine dark energy models have been tested and compared using the latest observational data, including type Ia supernovae, baryon acoustic oscillation, and cosmic microwave background. The cosmological constant (CC) model is found to be the best fit, with five other models providing a good fit to the current data.
Georges Belfort has made seminal contributions in liquid-phase pressure-driven membrane-based processes, bioseparations engineering, interfacial science, and affinity separations. He is honored by the American Chemical Society for his outstanding research and practice contributions to the advancement of science and technology.
Researchers have identified genetic mutations associated with elevated PSA levels in men diagnosed with prostate cancer, offering potential new biomarkers for disease monitoring. The study's findings suggest that sequencing of selected mitochondrial regions could provide valuable information for prognosis.
Scientists have successfully visualized adsorbed protein layers using evanescent wave imaging, demonstrating its potential for monitoring protein adsorption. The study optimized conditions by applying a polarized beam and incorporating a surface-enhanced medium, leading to significant increases in image contrast.
Researchers found that common genetic variants near aging-related genes influence the production of circular RNAs, which control INK4/ARF gene expression and risk of diseases like heart attack and stroke. Individuals with more of these circular forms have increased INK4/ARF gene expression.
A new study from Rice University found that players are more likely to imitate high-status leaders and ignore low-status leaders in a repeated public-goods game. Contributions from followers with low-status leaders dropped off even as their leaders increased their contributions, showing the importance of leader status on cooperation.
A new study found that botulinum toxin A causes muscle weakness in muscles far removed from the injection site, even after repeated use. The study also reveals muscle atrophy and loss of contractile tissue in non-injected limbs.
PlasmaButton therapy offers a new treatment option for benign prostatic hyperplasia (BPH), with benefits including excellent tissue ablation, minimal patient morbidity, and ease of use. The technology provides a virtually bloodless procedure, reducing complications such as urinary tract infections and renal failure.
A naturally occurring chemical found in soy could prove to be an effective new treatment for a fatal genetic disease that affects children. In mouse studies, genistein showed a significant delay in mental decline and corrected abnormal behavior.
Researchers propose a new branch of aerothermodynamics to study attached boundary layer flows, focusing on unsteadiness in vehicular environments. They have explored principles using simple models and investigated interaction characteristics between temperature and velocity fields.
Mark Bates has been awarded the GE & Science Prize for Young Life Scientists for his novel research on high-resolution imaging of biological cells and tissues. His technique, known as stochastic optical reconstruction microscopy, enables researchers to see previously hidden aspects of life with unprecedented detail.
A study reveals that many rare coral species in Hawaii may interbreed with more common species, making it challenging to determine their individual species identity. This uncertainty affects conservation efforts and taxonomy of the coral genus Montipora.
Researchers believe metabolic engineering could revolutionize the production of chemicals, replacing non-renewable resources with bio-based alternatives. Jay Keasling's work aims to engineer microbes to perform complex chemistry, expanding product availability and reducing costs.
Researchers at Johns Hopkins Medicine found that a set of specific interventions can lead to rapid improvements in hospital safety culture. The program, which includes training for local staff and executive buy-in, resulted in significant increases in positive safety attitudes among hospital workers.
A bacterium isolated from Mono Lake has been found to use arsenic as a building block for its growth and survival. The new finding has significant implications for the origins of life research and could redefine our understanding of what constitutes life.
The Euro-BioImaging project will develop a comprehensive plan to construct and operate a set of complementary imaging infrastructure facilities across Europe. This will enable scientists to access state-of-the-art imaging technologies, receive training, and facilitate the translation of basic results to medical applications.
Researchers used differential epistasis maps to study how genes interact in response to stress by DNA-damaging agents. The genetic network was found to completely reprogram itself, revealing functional relationships that would go undetected using other approaches.
Researchers in Rhode Island, led by Johns Hopkins Medicine, reduced central-line associated bloodstream infections to near zero using the widely-heralded Johns Hopkins checklist and other patient-safety tools. The intervention prevented 42 infections, saved 10 lives, and reduced ICU stays by 608 days.
Physicist Franz Pfeiffer's research on X-ray phase-contrast imaging has immense potential for applications in medicine and industry. His approach enables improved image contrast with lower doses of radiation, leading to better diagnostic success in tumor detection.
Researchers found that adolescent great whites struggle with capturing and killing large marine mammals due to their weak jaws. However, they can maintain high bite forces using a unique jaw muscle arrangement, a trait common among successful predators.