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Science News for December 2, 2016


Evaluation of scientific rigor in animal research

Researchers found that only 20% of applications and publications reported use of bias-reducing methods, but 86% of participants claimed to assign animals randomly to treatment groups. The study recommends more education and training for those involved in animal research to ensure scientific rigor.

SourcePLOS·JournalPLOS Biology·DateDec 2, 2016

Lung function decline accelerates in menopausal women

A longitudinal population-based study found that menopausal women experience an accelerated decline in lung function, with declines in forced vital capacity and forced expiratory volume in one second comparable to severe smoking. The study highlights the importance of maintaining respiratory health long after the menopausal transition.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateDec 2, 2016

Turning off asthma attacks

Johns Hopkins researchers have identified a critical cellular switch that turns on the inflammatory immune response contributing to asthma attacks. By inhibiting this pathway, they may be able to prevent continued inflammation and long-term structural changes in the lungs.

SourceJohns Hopkins Medicine·JournalJournal of Biological Chemistry·DateDec 2, 2016

E-cigarettes effectively deliver nicotine

E-cigarettes are effective at delivering nicotine, particularly for experienced users. The study found that newer generation e-cigarettes outperform first-generation devices in terms of nicotine delivery. However, the efficacy of e-cigarettes also depends on individual behavior and vaping habits.

SourceR&D at British American Tobacco·JournalAmerican Journal of Health Behavior·DateDec 2, 2016

What makes your voice yours?

UCLA researchers Patricia Keating and Jody Kreiman analyzed recordings from 50 women to identify acoustic parameters distinguishing their voices. The study aims to understand which characteristics make a speaker's voice recognizable and how much change is perceptible to listeners.

New test identifies high-risk liver patients

A new test has identified a gene signature related to the immune response in liver tissue of patients with high-risk Primary Biliary Cholangitis (PBC), a rare autoimmune condition. The test allows for early intervention with alternative treatments, increasing chances of success and potentially staving off the need for a liver transplant.

SourceNewcastle University·JournalEBioMedicine·DateDec 2, 2016

High-precision magnetic field sensing

Researchers developed a high-precision sensor to measure small variations in strong magnetic fields, enabling the detection of mechanical processes in the body. The technique has broad applications in medicine and biological research, including the development of new contrast agents for MRI.

SourceETH Zurich·JournalNature Communications·DateDec 2, 2016

Saturated fat could be good for you

A Norwegian diet intervention study found similar health effects of diets high in carbohydrates or fats, with substantial improvements in cardiometabolic risk factors. The study suggests that the quality of food is more important than the quantity of fat or carbohydrates, and that most healthy people can tolerate a high intake of satur...

SourceThe University of Bergen·JournalAmerican Journal of Clinical Nutrition·DateDec 2, 2016

New tool uses UV light to control inflammation

Researchers at Cornell University developed a chemical tool that controls inflammation using UV light, allowing for targeted therapy with minimal side effects. The method has potential applications in treating inflammatory diseases such as asthma and rheumatoid arthritis.

SourceCornell University·JournalChemical Science·DateDec 2, 2016

Fast, efficient sperm tails inspire nanobiotechnology

Scientists at Cornell University developed a system where enzymes are attached to nanoparticles to mimic the efficient energy-producing mechanism of sperm tails. The tethered enzyme system processes glucose to lactate more efficiently than free-floating enzymes, with potential applications in powering devices that carry out various jobs.

SourceCornell University·JournalAngewandte Chemie·DateDec 2, 2016