A new study by Northwestern University found that a home-based exercise program with wearable devices and telephone coaching did not improve walking ability in patients with peripheral artery disease. The researchers suggest that this approach may worsen pain for participants, limiting their activity levels.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that girls with recently diagnosed type 2 diabetes had a high rate of menstrual irregularities. Many of these girls also had high testosterone levels, suggesting PCOS as an underlying cause.
Researchers at University of Pennsylvania School of Medicine have identified five strategies to reduce unplanned acute care for cancer patients, including leveraging advanced big data analytics, team-based care, and early palliative care. These best practices aim to improve patient experience and reduce hospital utilization.
Researchers found patients in hospitals want to track their health data and partner with care teams. Patients are interested in using devices like Fitbits to manage chronic conditions but prefer collaborative approach.
Scientists propose a new model where a heavy layer of molten rock sits on top of the Moon's metal core, driving the dynamo and creating a strong magnetic field. This model explains the Moon's early strong magnetic field and its subsequent weakening.
Researchers at Wyss Institute for Biologically Inspired Engineering at Harvard developed a new genetic analysis technique that harnesses natural barcodes in human genomes. This allows for faster, cheaper, and simpler tracking of cell identities across experiments, enabling large pools of cells from multiple people to be analyzed.
Treating leg ulcers within two weeks improves healing rates by 12% compared to standard treatment, with a success rate of 85.6%. Early intervention helps patients recover quicker and reduces the risk of complications such as amputation.
A Danish-German research team has identified a novel long non-coding RNA, A-ROD, that enhances the production of specific proteins with involvement in cancer. The RNA functions as a lasso that brings transcription factors to specific sites in DNA to enhance gene expression.
A study from York University shows that cognitive behavioral therapy can significantly improve children's emotional regulation, including anxiety and other emotional challenges. The intervention, involving a computer program and family support, led to improved mental health outcomes in children with autism.
A recent study found that Veterans Health Administration (VHA) facilities have varying care practices for military veterans with chronic pain, leading to inconsistent rates of long-term opioid therapy. Facilities with a wider range of non-opioid treatment options had lower rates of opioid use among veterans.
A UCL-led study found that hospitals are more likely to diagnose dementia in patients who have been admitted for another reason. However, missed diagnoses persist, with one-third of people with dementia discharged without recognition, highlighting the need for better record-sharing and culturally appropriate assessments.
Purdue researchers have developed an online platform called the Social Media Analytics and Reporting Toolkit (SMART) that filters social media content according to key words and geographic regions. The tool is being used by first responders to analyze both live and historical data, helping them attend to certain areas faster.
A University of Oregon-led project found that high immune function during childhood is associated with significant growth reduction. Chronic exposure to parasitic worms was linked to reduced stature and lower-leg growth, highlighting the metabolic cost of a robust immune system.
Bariatric surgery induces changes in alpha cells to produce beneficial GLP-1, combating insulin resistance and islet dysfunction associated with type 2 diabetes. Researchers aim to develop a drug mimicking this effect, making surgery's benefits more accessible.
Researchers at Albert Einstein College of Medicine found that intense exercise reduces appetite by activating temperature-sensitive receptors in the hypothalamus, a region of the brain that regulates metabolism and weight. The study provides evidence that body temperature can act as a biological signal that regulates feeding behavior.
A study by Yale University researchers found that newspaper op-eds have a lasting impact on people's views, regardless of their political affiliation or initial stance. The study, which included experiments with the general public and elites, showed that op-eds can change minds on policy issues for a cost-effective estimated $0.50 to $...
Researchers have identified a new gene, ari-1, linked to aortic aneurysms in humans through a fruit fly study. The study found that mutations in the ari-1 gene disrupt mechanical sensing mechanisms in the body, leading to abnormal nuclei shapes and potentially contributing to the development of aortic aneurysms.
A fractal-shaped electrode design enhances charge delivery for smaller neural stimulation targets, potentially prolonging device lifespan and improving resolution. The new shape facilitates faster Faradaic charge transfer, resulting in more efficient energy use.
Researchers found that users consider personalized apps more trustworthy when consulted about store preferences, leading to better usability and engagement. Higher perceived transparency reduces privacy concerns and boosts user involvement.
A new study from Oregon State University-Cascades found that millennials are not getting the message about sun safety and the dangers of tanning. The research suggests that those with lower self-esteem and higher narcissism rates are more likely to exhibit addictive tanning behavior, driven by a desire for improved appearance.
A machine learning approach developed for Mars feature mapping has been adapted to assess the effect of treatments on tumors. The technique provides a four-fold increase in precision and enables researchers to present findings with confidence.
Tropical Cyclone Fakir is experiencing severe vertical wind shear, causing it to deteriorate rapidly. The system is expected to dissipate by April 26 due to unfavorable environmental conditions.
A Baylor University study found that employees who believe they are more ethical than coworkers experience negative emotions, which can lead to mistreatment and exclusion of those workers. The research highlights the importance of considering ethics and performance when rewarding employees.
A new genetic analysis reveals that two male whales fathered over half of the calves born since 1990, indicating inbreeding in the Southern Resident killer whale population. The limited breeding number reduces the population's resilience to change, potentially compromising individual animals' survival.
Researchers aim to determine when the pause in transcription first appeared in evolution by studying various organisms and plant life. They hope this investigation will help narrow down the origin of the pause, shedding light on how complicated life arose on Earth.
Researchers analyzed data on intimate partner homicide in North Carolina between 2004-2013. They found that guns were the primary weapon in 7 out of 10 cases, leading to an average of 50% more deaths compared to similar crimes committed with other weapons.
Researchers at the University of Illinois have developed a tunable infrared filter made from graphene, allowing soldiers to change the frequency of a filter simply by controlled mechanical deformation. This breakthrough enables real-time chemical detection and identification, overcoming limitations of conventional filters.
The fifth Act 54 five-year report assesses the impact of long-wall, room-and-pillar, and retreat mining methods on surface structures and water resources. The study provides vital information for environmental remediation and restoration efforts in Pennsylvania.
Researchers found improved measures of cardiovascular health, beneficial changes in fat tissue, and reduced risk of diabetes in obese women with PCOS who used a hot tub regularly. Heat therapy may reverse some of the inflammation in fat that causes metabolic health impairment.
A study published in the Journal of Clinical Psychiatry found that over a quarter of young people seeking treatment had a history of at least one overdose. Factors associated with increased overdose risk included alcohol, cocaine, and amphetamine use, as well as psychiatric conditions like depression and anxiety disorders.
Average winter wave heights have increased by more than 10mm/year along Scotland and Ireland's coastlines, leading to higher wave heights during extreme weather conditions. The study's findings are crucial for predicting future wave heights and protecting coastal communities across Western Europe.
Salk Institute researchers have generated aggressive glioblastoma multiforme tumors in human cerebral organoids using CRISPR-Cas9 tool. The new model could be used to study tumor progression, investigate new drugs or personalize treatments for patients.
Researchers at the University of Freiburg have discovered how flavins work with oxygen to activate enzyme cofactors, shedding light on their role in metabolic processes and biotechnological applications.
A study published in Psychological Science found that imagining a positive outcome for an upcoming event can color one's memory of the event, leading to a rosier reflection. Participants who imagined scenarios in a positive light also rated actual events more positively, suggesting that optimism can transfer to a more positive recall.
Researchers at Utah State University studied the physics behind a unique underwater phenomenon resembling the Matryoshka doll. They developed a new dimensionless number, the Matryoshka number, which predicts the formation of nested cavities under certain conditions.
Research by Dr Heather Ford and colleagues found that female scientists are at a disadvantage in presenting their research, particularly in early career stages, where men dominate senior roles. The study calls for increased opportunities for students and early-career researchers to present at conferences.
A new study by Georgia Tech and Georgia Aquarium explores the diverse community of marine microorganisms living in the aquarium's water, revealing dynamic changes over time. The research aims to improve our understanding of these tiny organisms and their impact on aquatic ecosystems.
The ATS Foundation and ResMed have partnered on a new two-year research fellowship to study sleep apnea and positive airway pressure. This funding will support future leaders in the sleep field and help patients with sleep apnea, a public health crisis that affects millions worldwide.
Researchers have created a wide-bandgap semiconductor called gallium oxide (Ga2O3) that can be engineered into nanometer-scale structures to facilitate high-speed electronics. The new material has demonstrated record mobilities and quantum transport properties.
NASA is studying four potential flagship missions to explore the universe, including direct imaging of Earth-like planets and investigation of first black holes. The agency will use advanced tools to overcome technical challenges and achieve unprecedented picometer-level stability.
According to a nationwide analysis, approximately 2.6 million American children and adolescents had diagnosed anxiety and/or depression in 2011-12. This represents about 5.3% of the population, with current anxiety or depression affecting around 65,000 parents about their children aged six to 17 years.
Researchers in China have engineered a Chinese shrub to produce high levels of artemisinin, a potent antimalarial compound. The study's findings provide new insights into the metabolic pathway involved in artemisinin biosynthesis and offer a potential solution to address global malaria-related deaths.
Researchers found that adults on the autism spectrum have increased use of primary care, mental health services, and laboratory services, but lower use of gynecology visits and cervical cancer screening. The study highlights the importance of considering autism throughout the lifespan and emphasizes the need for better access to afford...
Guus Rijnders has been awarded the Julius Springer Prize for Applied Physics for his pioneering research on pulsed laser deposition and its applications in interface engineering. His work focuses on creating complex materials with novel functionalities, including brain-inspired electronics and sensors.
Children born to youngest and oldest mothers have higher rates of developmental vulnerabilities at age 5. Socio-economic factors explain at least half the increased risk, with 40% of children born to mothers aged 15 years or younger being developmentally vulnerable.
The study found that five to nine orphan medicines were available in ten European countries, while all ten medicines were only accessible in three countries: the Netherlands, Malta, and Poland. The availability of these medicines varied significantly across different countries.
An international team found a fundamental law regulating galaxy cluster growth using gravitational lensing data from NASA's Hubble Space Telescope and Subaru Telescope. The law indicates that clusters are still growing by drawing surrounding substances with their strong gravity.
Researchers at UW-Madison have developed a new approach to noninvasively measure tendon tension while a person is engaging in activities like walking or running. The technology uses vibrational characteristics to assess tendon force, providing insights into motor control and mechanics of human movement.
Researchers have developed a real-time thermal imaging method to guide minimally invasive brain tumor treatments. This technology enables doctors to precisely deliver the right dose to the right location, reducing risks and costs associated with follow-up imaging studies.
Researchers use DNA-PAINT technique to visualize individual strands in DNA origami nanostructures, revealing the robustness of assembly and incorporation efficiency of staple strands. The results show that variations in structure formation speed have little influence on overall quality, but some sites remain unoccupied.
A randomized clinical trial found that combining aspirin with ticagrelor improved patency of grafted saphenous veins in patients undergoing coronary artery bypass grafting. This reduces the risk of vein graft failure and associated worse long-term outcomes.
A new study suggests that galaxies similar to the Milky Way should host multiple supermassive black holes, as predicted by a state-of-the-art cosmological simulation. The wanderings of these black holes are unlikely to affect our solar system due to their vast distances and low accretion rates.
A new study implicates a role for light-induced electrical activity in controlling chemical codes in the brain, potentially leading to chemical imbalances underlying mental illness. The researchers found that manipulating brain electrical activity prevented neurotransmitter switching associated with anxious and depressed behavior.
A new study published in Molecular Plant-Microbe Interactions reveals the mechanism by which antibiotics kasugamycin and blasticidin S kill fire blight bacteria in apple and pear trees. The researchers found that the antibiotics target a critical gene, ksgA, leading to bacterial death.
Researchers from ITMO University have discovered a new mechanism for neutron star radio emission, based on the transitions of particles between gravitational states. This phenomenon is similar to laser amplification and was first observed in electrons on the surface of neutron stars, consistent with real experimental observations.
Research led by Dr. Soren Brothers found that Lake Superior absorbs atmospheric CO2 from May to October, but expels it during winter due to El Niño events and climate change. The study, published in Limnology and Oceanography, suggests a potential marine-atmospheric feedback loop with global warming.
The pin mold fungus Phycomyces blakesleeanus uses a gene from bacteria to create large gravity-sensing crystals that help it grow upright. Genetic analysis reveals the role of horizontal gene transfer in acquiring this unique trait, providing insights into the evolution of adaptation.
Researchers found patients in the Prostate Cancer Intervention versus Observation Trial (PIVOT) to be up to eight times more likely to die than real-world patients. The study's patient population was also older and sicker, with an average age of 67 at diagnosis.
Researchers at Eindhoven University of Technology have developed an artificial leaf that can produce chemicals using sunlight, increasing efficiency by 20%. The 'mini-factory' uses a clever feedback system costing less than 50 euros to automatically adjust production levels.
A novel technique called radiation segmentectomy (RS) uses yttrium-90 to destroy tumors while sparing surrounding tissue. The procedure has shown positive response in 71% of patients and improved survival outcomes, with a median overall survival of 6.7 years.