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Science News Archive 2018 - Page 460


Page 460 of 473

New Carnegie Mellon dynamic statistical model follows gene expressions over time

Researchers at Carnegie Mellon University have developed a new dynamic statistical model to visualize changing patterns in networks, including gene expression during developmental periods of the brain. The model, Persistent Communities by Eigenvector Smoothing (PisCES), combines information across multiple networks over time to identif...

SourceCarnegie Mellon University·JournalProceedings of the National Academy of Sciences·DateJan 15, 2018

An efficient approach of conjugated tetraenes from butadiene and alkynes

Researchers at Tokyo University of Agriculture and Technology have developed a one-pot approach to synthesizing conjugated tetraenes from inexpensive reagents, eliminating waste production and simplifying the process. The new method has potential applications in electronic materials, natural products, and pharmaceutical molecules.

Mapping the social landscape

Scientists discovered a sub-population of neurons in bats' brains that encode the specific location of other bats nearby. These 'social place cells' support the idea that our brains create a cognitive map not just of our location, but also one that includes social mapping.

SourceWeizmann Institute of Science·JournalScience·DateJan 14, 2018

New warning system discovered in the immune defense

Researchers at Linköping University have discovered a previously unknown warning system in the immune defense that triggers an alarm, sending signals to surrounding cells. This process involves the release of mitochondrial DNA strands by white blood cells in response to infections like bacteria and viruses.

SourceLinköping University·JournalProceedings of the National Academy of Sciences·DateJan 12, 2018

Maintaining canola oil quality

Researchers at Tohoku University developed a new technique to analyze isomers in edible oil using HPLC-MS/MS, revealing the specific oxidation compounds in canola oil resulting from heat and light. The study suggests packaging canola oil in dark containers and adding antioxidants like carotenoids to reduce oxidation.

SourceTohoku University·Journalnpj Science of Food·DateJan 12, 2018

Scientists identify a key mechanism regulating a protein required for muscle and heart function

Researchers have identified a crucial mechanism in the regulation of titin protein, a key player in skeletal muscle and heart function. The study found that disulfide bonds play a significant role in determining titin's elastic properties, and their formation can cause major changes in the protein's elasticity.

A society divided by reconstruction

The reconstruction of Banda Aceh after the 2004 tsunami has led to socio-economic segregation, with lower-income residents facing increased exposure to coastal hazards. The study found that many tsunami survivors preferred to move inland, but were unable to afford it, leading to a divide between affluent and poorer residents.

SourceETH Zurich·JournalNature Sustainability·DateJan 12, 2018

Scleroderma study: Hope for a longer life for patients with rare autoimmune disorder

A new clinical trial has found that a stem cell transplant treatment can significantly improve the survival and quality of life for patients with severe scleroderma. The experimental procedure uses chemotherapy and radiation to destroy the body's malfunctioning immune system, then replaces it via a stem-cell transplant.

SourceUniversity of Virginia Health System·JournalNew England Journal of Medicine·DateJan 12, 2018

Cancer's gene-determined 'immune landscape' dictates progression of prostate tumors

Researchers at Beth Israel Deaconess Medical Center discovered that specific genetic events drive distinct immune cell compositions in primary prostate tumors, dictating tumor progression and response to therapy. Profiling patients' tumors based on this new information could lead to more successful clinical trials and tailored therapies.

SourceBeth Israel Deaconess Medical Center·JournalNature Medicine·DateJan 12, 2018

New method to map miniature brain circuits

Scientists have developed a new technique to map electrical circuits in the brain with unprecedented accuracy, revealing the detailed architecture of microcircuits. This breakthrough enables researchers to understand how the brain processes complex information and may lead to insights into behavior and sensory processing.

SourceThe Francis Crick Institute·JournalNature Communications·DateJan 12, 2018

New therapeutic approach for advanced lung disease

Researchers have identified new drug candidates that target multiple protein kinase families to reduce inflammation in COPD. The Narrow Spectrum Kinase Inhibitors (NSKIs) show promising anti-inflammatory effects and may constitute a breakthrough in treating advanced lung disease.

SourceRuhr-University Bochum·JournalJournal of Allergy and Clinical Immunology·DateJan 12, 2018