A study by University of British Columbia researchers found that one in ten Canadians prefer open relationships, with 12% reporting this as their ideal type. Despite the prevalence, stigma and difficulty discussing preferences may deter individuals from pursuing these relationships.
The largest study of childhood cancer after IVF found that IVF babies are at a higher risk of certain cancers, particularly hepatic tumors. The study did not find any association between IVF and an increased risk of other specific cancers.
A Jurassic fossil find reveals that insects began serving as pollinators before the emergence of flowering plants. The ancient fly's proboscis was used to access sugary secretions in ancient gymnosperms, laying the foundation for pollination mutualism.
Researchers at University of Cologne create one-dimensional wire to witness behavior of trapped electrons. They discover two sets of standing waves, representing spin density and charge density waves, a phenomenon predicted by Tomonaga-Luttinger liquid theory.
A Swedish review of out-of-hospital cardiac arrest data shows compression-only CPR increased six-fold and doubled the chance of survival, compared to no CPR. Bystander CPR rates nearly doubled over an 18-year period, with patients receiving standard or hands-only CPR being two times more likely to survive 30 days.
Teng Zhang's NSF CAREER Award will support his research on interface mechanics in soft materials, aiming to develop better materials for wound healing, biological joint diagnosis, and underwater adhesives. The award also enables educational outreach and the integration of modeling simulation tools into Syracuse University's curriculum.
A new study has found that 58% of people displaced following the civil war in Sri Lanka have suffered from mental health problems. The research, led by Dr Shannon Doherty at Anglia Ruskin University, also highlights the significant unmet mental health needs in the region.
Researchers have uncovered ancient ritual offerings near Lake Titicaca that pre-date the arrival of the Incas by several centuries. The findings suggest a more complex and ambitious spiritual system among the Tiwanaku people, who developed in the area between 500-1,100 AD.
A new study by University of Pittsburgh researchers has identified a previously unknown mechanism used by tumors to suppress the immune system. The study found that tumors use two types of immune cells, regulatory T cells (Tregs), to release inhibitory cytokines, which activate a protein called BLIMP1 and disable killer T cells.
The anti-PD-1 monoclonal antibody pembrolizumab showed promising antitumor activity with durable responses in patients with pretreated, advanced small cell lung cancer (SCLC). The study found an objective response rate of 19.3% and a median progression-free survival of 2 months.
Scientists have developed edible antibodies that can survive digestion and reach the gut, offering an alternative to traditional treatments. The technology has potential applications in fighting gut infections, treating inflammatory disorders, and preventing diarrhea in pigs and humans.
A phase III clinical trial found gilteritinib superior to standard chemotherapy in improving overall survival for patients with relapsed or refractory AML harboring a FLT3 mutation. Gilteritinib's relatively low toxicity enables outpatient management, shifting the treatment paradigm.
Researchers have found that water accelerates the conversion rate of furfural by a factor of two to three. The presence of water enables hydrogenation to occur in the liquid phase instead of on the catalyst surface.
A UCL-led study found that engaging households in evidence-based face-to-face workshops increases long-term disaster preparedness. Households that received training showed significant improvements in safety measures such as securing objects and having functioning smoke detectors.
Scientists found that platelets play a key role in the development of fatty liver disease and liver cancer. Blocking platelet function or attaching to specific molecular sites may help prevent the condition.
A recent study found that climate change can have long-lasting negative impacts on dolphin populations, with a 12% decrease in survival rate following a heatwave in Shark Bay, Western Australia. The researchers also observed fewer births among female dolphins, which persisted for at least six years.
A new study estimates that air pollution from corn production causes 4,300 premature deaths in the US each year, resulting in a monetized cost of $39 billion. The health damages vary by region, with some areas experiencing greater damage than their market price.
Scientists have discovered a new method to control icing on next-generation aircraft using plasma actuators. The technology can transfer heat locally while mixing well with incoming airflow, preventing stress on composite materials. Researchers tested three configurations of actuators in high-speed cameras and infrared thermal imaging.
A Phase II trial at MD Anderson Cancer Center showed umbralisib to be an effective treatment for patients with relapsed marginal zone lymphoma, achieving a 55% partial or complete response rate. The drug was well-tolerated, with a 71% progression-free survival after one year.
Heavy drinking during adolescence reduces brain growth in male and female rhesus monkeys, affecting white matter and thalamus development. Research supports potential link to problematic drinking later in life.
Researchers at the University of Birmingham have developed a way to combine multiple skyrmions into 'skyrmion bags' that can store and transfer data more efficiently. This breakthrough technology has the potential to increase data storage capacity, reduce power consumption, and pave the way for next-generation computing devices.
The use of medically assisted death (MAID) has resulted in ethical concerns over body donations to anatomy programs in Canada. McMaster University's head of anatomy, Bruce Wainman, argues that guidelines are needed to ensure respectful treatment of MAID donors and avoid pressuring vulnerable individuals into donation.
Researchers at Tohoku University have developed a technique to transform copper into a material that mimics properties of gold and silver. The new medium, made of copper nanoparticles, has applications in the production of electronic devices and is suitable for environmentally friendly printing technologies.
Researchers found signature of 16 disease-related microbial species associated with colorectal cancer and identified Fusobacterium nucleatum and choline trimethylamine-lyase gene in fecal samples. The study paves the way for non-invasive predictive tests for different populations.
New research published in CMAJ found a higher risk of severe maternal complications after cesarean delivery, particularly among women aged 35 and older. Women under 35 had 1.5 times the odds of complications, while those over 35 had almost twice as high odds.
A combination of ipilimumab and nivolumab demonstrated clinical benefit among patients with high-grade neuroendocrine carcinoma in a phase II clinical trial. The therapy showed an overall response rate of 24% and improved progression-free survival, offering new hope for this patient population.
A study found that excess body weight before age 50 is strongly associated with an increased risk of dying from pancreatic cancer. The research, which analyzed data from over 963,000 adults, suggests that excess weight measured earlier in adulthood may be more closely linked to pancreatic cancer risk than previously thought.
A mesothelin-targeted CAR T-cell therapy demonstrated antitumor activity and acceptable toxicity in a phase I clinical trial for patients with malignant pleural disease. The therapy showed significant tumor regression and reduced mesothelin-related peptide levels in the blood.
Adding savolitinib to osimertinib yields clinical responses in patients with EGFR-mutant non-small cell lung cancer and MET-driven acquired resistance. The combination therapy demonstrates efficacy in a patient population for whom chemotherapy is the current primary treatment option.
Researchers have identified bacteria with promising antibiotic activity against known pathogens in the protective mucus that coats young fish. The study found five bacterial extracts strongly inhibited methicillin-resistant S. aureus and three inhibited Candida albicans, a fungus pathogenic to humans.
Researchers developed liquid crystal technology that can block a wide range of laser wavelengths, including red, blue, and green. The system uses a voltage-controlled phase change to scatter light and block laser beams.
A new combination of immunotherapy and chemotherapy has caused tumors to shrink in 83% of patients with metastatic pancreatic cancer. The treatment, involving a CD40 antibody, checkpoint inhibitor, and standard-of-care chemotherapy, showed manageable side effects, suggesting a durable response.
Researchers create covalent nanoparticles to deliver naloxone for 24-hour protection against morphine and fentanyl's effects. The nanoparticle system shows promise in treating fentanyl overdoses and could potentially replace short-acting naloxone as an antidote of choice.
Researchers have identified key compounds responsible for the flavor and aroma of Tennessee whiskey. By studying the effects of the Lincoln County Process, distilleries can optimize their production to achieve the desired flavor profile.
A new experimental glioblastoma vaccine developed by Jefferson and Imvax has shown promising results in a phase Ib clinical trial. The treatment was found to slow tumor recurrence and prolong patient survival in patients with newly diagnosed glioblastoma multiforme.
A phase I clinical trial found that a combination of chemotherapy and HER2-targeted CAR T cells is safe and effective in treating advanced sarcoma, with some patients experiencing complete responses. The therapy showed promising antitumor activity and minimal treatment-related toxicities.
A combination of ipilimumab and nivolumab has been shown to shrink tumors in patients with high-grade neuroendocrine carcinoma by 42 percent, while all low-grade patients did not see a response.
Researchers have discovered a correlation between estrogen byproducts and survival rates for women with breast cancer, with higher levels of the "good" metabolite associated with reduced mortality. The study suggests that measuring these byproducts may help predict prognosis after breast cancer diagnosis.
A study from the European Society of Cardiology reveals that nighttime trips to the bathroom may be a sign of high blood pressure or excess fluid in the body. The researchers suggest that individuals experiencing nocturia should consult their doctor about their blood pressure and salt intake to address potential hypertension.
Researchers found that obesity at older ages is linked to worse outcomes, with higher tumor growth in obese mice compared to lean mice. They also discovered a connection between leptin, a biological signal released by fat tissue, and increased numbers of tumor-initiating cells.
Researchers have developed a new way to visualize nano objects using superlenses and titanium oxynitride films, achieving spatial resolutions of 8 nm and 80 nm. This breakthrough enables non-destructive analysis and 3D visualization without the need for fluorescent labels.
A Columbia University study found that adversity-induced disruptions in gut microbes are associated with changes in brain function in young children. The research linked gastrointestinal symptoms in childhood to potential emotional health issues later in life.
Researchers evaluated the safety and effectiveness of uterine artery embolization (UAE) in patients with various autoimmune diseases. UAE was technically and clinically successful in all patients, with no significant difference in volume reduction rates between groups.
Researchers at Rice University discovered that PTFE stir bars react with chemicals in an unexpected way, affecting the modification of nanotubes. This discovery highlights the importance of choosing inert materials in laboratory settings.
Researchers designed proteins that can assemble into complex structures using supercomputers and artificial charges. The stacked octamer structure consists of 16 proteins, resembling a braided ring with highly ordered and specific interactions.
Physicians at the University of Vienna have developed a novel method to cool nanoparticles using quantum optics, enabling unprecedented control over particle motion in ultra-high vacuum. The approach, inspired by atomic physics, harnesses scattered light from an optical tweezer to effectively cool particles' kinetic energy.
A new CU Anschutz study found that physical activity is essential for maintaining substantial weight loss, rather than diet. Successful weight-loss maintainers engage in high levels of physical activity to prevent weight regain.
Researchers create green fluorescent protein-based biosensors to probe energy metabolism in living cells, enabling multicolor imaging and visualization of multiple molecules. The sensors achieve up to a seven-fold increase in fluorescent brightness in response to glucose concentrations.
A team at the University of Delaware has engineered a silicon-graphene device that can transmit radiofrequency waves in less than a picosecond, enabling faster communications. The device combines the benefits of silicon and graphene, with improved carrier mobility and electrical properties.
Scientists at University of Freiburg create three-dimensional hollow structures in quartz glass using Glassomer process. This breakthrough enables the production of optical waveguides and microfluidic channels, previously difficult to manufacture due to glass's chemical resistance.
A recent study published in The FASEB Journal found that low oxygen levels during fetal development can lead to premature ovarian ageing and reduced egg availability. Researchers exposed pregnant rats to chronic hypoxia, leading to accelerated ageing of the ovaries and fewer eggs available for future reproduction.
Researchers have developed a new methodology that allows solid state lighting to measure and self-adjust its spectral power distribution based on environmental conditions. This enables the system to maintain consistency and stability over time, making it suitable for applications requiring precise light spectra.
Researchers use metal nanoparticles to detect single target molecules in paper-based tests, overcoming limitations of conventional dyes. The results enable ultra-sensitive diagnostics with limitless applications in medicine, forensics, and environmental safety.
Genome editing enables crop development with resistance to pests, diseases, drought, and heat, reducing losses and chemical pesticide sprays. However, regulatory hurdles in Europe may hinder the adoption of these technologies, posing a risk to developing countries.
Researchers warn that increased tariffs on US soya bean exports to China could trigger extensive tree-felling in Brazil's Amazon rainforest. The study suggests measures to reduce deforestation, including removing trade tariffs and improving environmental protection schemes.
Astronomers estimate that Messier 11 formed 220 million years ago and will disperse in a few million years as its stars are ejected by stronger gravitational forces.
Paleontologists uncover part of a skull from the Liscomb Bonebed, revealing the presence of lambeosaurines in the Arctic during the Late Cretaceous. The discovery suggests that hadrosaurines and lambeosaurines may have had different habitat preferences.
Researchers from Rochester Institute of Technology and Georgia Tech developed a new approach to simulate the heart's electrophysiology in real-time, allowing doctors to better discuss life-threatening heart conditions with patients. This method uses WebGL code to repurpose graphics cards for faster scientific computing applications.
A nationwide survey analysis found that more Americans view e-cigarettes as harmful as, or more so than, traditional cigarettes. The shift in perception may have led to fewer smokers switching to e-cigarettes, highlighting the need for accurate risk communication.
Tropical Cyclone Joaninha's maximum sustained winds dropped to 65 knots on March 29, 2019, after being pushed away from its center. The storm was expected to weaken further due to increasing wind shear and cooler sea surface temperatures.