A new study suggests that targeting a single brain region called the subgenual anterior cingulate cortex (sgACC) could lead to better outcomes for people with depression and anxiety. Over-activity in sgACC underlies several key symptoms of mood and anxiety disorders, but an antidepressant only successfully treats some of the symptoms.
Thomas McAndrew's novel framework combines computational models with human understanding of social determinants of health to better forecast COVID-19 outbreaks. His research aims to inform public health decision-making and reduce morbidity and mortality, providing actionable predictions for policymakers and the general public.
A study published in Nature Microbiology reveals that drug-resistant E. faecium can spread within hospitals despite deep cleaning, with high rates of infection found in vulnerable patient groups. The bacteria's ability to evade cleaning measures poses a significant challenge to infection control.
Researchers have discovered that arbuscular mycorrhizal fungi can reduce SCN populations by up to 80% and suppress egg hatching by 30%. This finding opens new avenues for biological control and provides an additional management tool to mitigate the impact of SCN on soybean production.
A team of biologists discovered that phytoplasma effector proteins interact with specific molecules in plant hosts, causing developmental abnormalities and devastating changes. The research found that the effector proteins adopt a structure similar to their target host molecules, allowing them to bind and cause harm.
Researchers will study and conduct experiments using femtosecond laser diagnostics to measure gas properties in plasma flows. The collaboration aims to better understand heat shields for hypersonic vehicles and space exploration applications.
A collaborative team developed an organs-on-a-chip system to monitor heart toxicity from breast cancer drugs. The dual-organ system closely mimics bodily tissues and provides evidence that the interplay between the heart and breast cancer tissues influences cell function and disease progression.
Researchers developed a hybrid sliding-rocking bridge design that sustains less damage compared to conventional bridges. The new design allows for quick and cost-effective repairs, making it more beneficial in the long run.
A massive methane release occurred in a deep ocean natural gas reservoir during the Pliocene, potentially affecting atmospheric concentrations. The study estimates that up to 27 teragrams of methane could have reached the atmosphere over 8 months, equivalent to 10% of current global annual emissions.
Researchers studying vaping and secondary exposure to e-cigarettes warn that adolescent use is at epidemic proportions. The study aims to uncover health effects of e-cigarettes on younger patients and explore the risks of secondary exposure.
Researchers at the University of Barcelona have identified new genes in the BEX/TCEAL cluster that are related to autism spectrum disorder and other neurological diseases. The study used animal models to describe molecular mechanisms involved in the development of the neocortex in humans and other placental mammals.
A study examined the impact of COVID-19 on depressive symptoms among high-risk individuals in the UK. The results showed a significant increase in depressive symptom severity during the pandemic.
Research using functional MRI found that brain networks involved in movement planning and execution are activated differently based on the type of movement performed, even when using different body parts. The study suggests that these brain functions emerge from innate constraints in early development.
Researchers have developed a form of gold nanotubes that can target and kill mesothelioma cancer cells using light. The nanotubes are made in a two-step process and have physical properties that can be tailored for enhanced therapies.
Weidong Zhou, a UT Arlington electrical engineering professor, has been named a fellow of the Optical Society (OSA) for his significant contributions to photonic crystal membrane lasers and hybrid nanomembrane optoelectronics. His research involves developing on-chip systems for healthcare applications and efficient, scalable lasers fo...
A study by the University of Basel found that online platforms have a positive impact on volunteer mobilization, willingness, and satisfaction. Volunteers who were more afraid of catching the virus experienced higher satisfaction through boosts in self-confidence. The findings suggest that online platforms can channel oversupply and re...
Researchers found that specific chemotherapy agents increase the likelihood of developing therapy-related acute myeloid leukemia or myelodysplastic syndrome. CH mutations are more frequent in genes protecting the genome from damage, such as TP53.
During the COVID-19 pandemic, hospitalizations for non-COVID-19 related conditions increased significantly in a New York health system. The study found that nearly half of all hospitalizations were due to these chronic and acute conditions.
A study led by George Hajishengallis found that targeting the DEL-1 molecule could be an effective way to treat inflammatory and autoimmune conditions. The researchers discovered that DEL-1 promotes the generation and immunosuppressive activity of regulatory T cells, which are crucial in maintaining health.
Organic solar cell efficiencies are limited by electron affinity and ionization energy offsets. Researchers discovered that Förster resonance energy transfer competes with electron transfer, hindering charge separation. The team plans to design new materials with enhanced charge generation and reduced energy losses.
Researchers at Ohio State and the University of Michigan discovered a new type of immune cell that rescues damaged nerve cells from death and partially reverses nerve fiber damage. The unique cell subset promotes nervous system repair and has been identified in human immune cells with similar characteristics.
A study by George Washington University researchers analyzed Google Trends data to assess public perception of COVID-19 exposure and disease prevalence. The team found that specific queries related to testing and diagnosis were associated with higher SVI values in states with the highest COVID-19 cases.
A new study by NYU College of Dentistry found that half of US dentists experienced verbal or reputational aggression in the past year, while nearly a quarter endured physical aggression. The rates of patient aggression toward dentists are high and comparable with those reported in other health care settings.
The NRG-RTOG 0712 trial demonstrated high efficacy rates for both gemcitabine and daily radiation regimens, with 79% and 85% distant metastasis-free rates at 3 years, respectively. The findings confirm the acceptance of these treatments as alternatives to cystectomy.
ACP leaders compared the healthcare proposals of President Trump and former Vice-President Joe Biden to their comprehensive framework for improving healthcare in the US. The proposals were evaluated on eight key challenges, including universal coverage, pre-existing conditions, and prescription drug pricing.
New study uses phylogenetic information to estimate timing of Himalayan uplift and origin of biodiversity. The Stepwise Hypothesis is supported by in situ diversification and dispersal rates, while the Late Orogeny Hypothesis is rejected due to inconsistencies with origination and peak diversification times.
Researchers found previously unknown lead compounds in ancient Egyptian red and black inks, suggesting they were used as a drying agent. The discovery challenges previous understanding of ancient lead-based pigments and may indicate widespread use of similar techniques earlier than thought.
The Partnership to Advance Throughput Computing (PATh) aims to advance distributed high-throughput computing technologies and extend adoption among researchers and educators. Researchers from top institutions will collaborate on the project, focusing on automation and leveraging massive networks of computers.
As the US faces rising COVID-19 cases, essential hospitals call on communities to follow basic health measures like washing hands, wearing masks, and maintaining distance. The nation's most vulnerable populations are disproportionately affected by COVID-19.
The study provides new insights into the asteroid's composition, suggesting it may be a dense, metallic object made of iron and nickel. The findings also indicate that oxidation is occurring on the surface, which could be a result of solar wind interaction.
A new DNA test developed by Flinders University can accurately determine the legal status of seized ivory samples, even in highly degraded state. The technique has shown 100% identification accuracy and correct assignment in the legal status of 227 highly degraded ivories.
A study estimates that long-term exposure to air pollution increases COVID-19 deaths by 15% globally, with higher proportions found in Europe and East Asia. Air pollution exacerbates health outcomes by aggravating co-morbidities and causing inflammation, leading to increased vulnerability to COVID-19.
The study found that MFS was strongly correlated with OS (τ = 0.86), while BF and DM were only moderately and weakly correlated with OS, respectively. The analysis suggests that researchers should be cautious when inferring clinical benefit from studies using biochemical failure as a surrogate for overall survival.
Researchers will present on anti-amyloid treatments and new late-stage clinical trials for Alzheimer's. NIA is funding over 230 active clinical trials to support the development of new treatments.
Researchers found that reduced insect density influences plant composition and development, with dominant plant species becoming more prevalent. This can lead to mismatches between plant and animal species, causing adverse consequences for the ecosystem.
The NanDeSyn Database collects and integrates functional genomics data for industrial microalgae, including genome sequences, gene annotations, and transcriptomes. This will facilitate research cooperation among the global Nannochloropsis community to develop the microalgae as a chassis for photosynthetic production of oils.
The study identifies four distinct states of cellular senescence, each characterized by changes in metabolic and epigenomic processes. These states are linked to different levels of inflammation and metabolism, offering new insights into the aging process and potential ways to promote healthy longevity.
New study shows ocean acidification influences carbon content of sinking particles, affecting biological pump. The results, published in Nature Climate Change, indicate highly variable responses to CO2, with bacterial and animal plankton playing a key role.
A study in rural Borneo found that healthcare exchange programs reduced deforestation by 70%, preserving forest carbon stores. Clinic access was high but highest in districts with logging agreements, highlighting community engagement as key to success.
A University of Central Florida researcher has created a new technique to keep lithium-ion batteries from degrading over time. The method involves applying a thin film-like coating of copper and tin to the anode, significantly reducing degradation by more than 1,000 percent.
Researchers found that PTSD and a variant in the klotho gene interact to cause premature aging in brain tissue, accelerating epigenetic aging. This interaction may lead to increased risk of neurodegenerative diseases like Alzheimer's.
Researchers at the University of Tsukuba found that hydrogen sulfide is essential for maintaining normal breathing patterns in mammals. The production of hydrogen sulfide allows brain regions responsible for controlling breathing to function normally.
Researchers measured the spectrum of a rare hot Neptune exoplanet, revealing evidence of molecular absorption in its atmosphere. This detection provides clues on the origin of the planet and how it managed to hold onto its atmosphere.
Researchers at Oregon State University found that a type of gut bacteria associated with inflammation and cancer can help prevent cardiovascular disease by metabolizing trimethylamine, a compound linked to fatty plaque buildup in arteries. A diet rich in animal-based foods is often considered a risk factor for cardiovascular disease.
A phase II trial found no statistically significant overall survival differences between dose-intensification radiation therapy (IMRT) and standard-dose radiation therapy with temozolomide treatments. However, MGMT methylation and RPA were predictive of progression-free survival.
This study highlights the importance of evenness in assessing sustainable development goals, revealing a bottleneck in China since 2013 due to stagnant progress in some SDGs. Regional integration and cooperation are proposed as effective strategies for holistically achieving SDGs across regions.
Researchers reconstructed evolutionary events based on genetic changes, finding complex cellular machinery evolved before mitochondrial symbiosis. The study suggests cell complexity increased before acquiring mitochondria, challenging current understanding of eukaryogenesis.
A new study by Stanford researchers finds that deforestation in an Indonesian national park declined 70% after an affordable health clinic opened, preserving carbon sinks and reversing poverty. The clinic's success demonstrates a holistic approach to addressing human health and environmental conservation.
Researchers found that bats lack AIM-2 receptors, which could reduce inflammation and allow viral reservoirs. In vitro experiments showed partial restoration of inflammasome signaling when human AIM-2 genes were introduced into bat cells.
A new method using noncombustible carbon textile grid and cement mortar doubles load-bearing capacities of structurally deficient concrete structures, increasing their usable lifespan threefold. Construction costs are reduced by 40% compared to existing methods.
A new analysis reveals that improving healthcare in rural Indonesia reduced incentives for illegal logging, resulting in a 70% decline in deforestation and over $65 million worth of avoided carbon emissions. The innovative clinic model provides a blueprint for preserving biodiversity while reducing poverty and illness.
Researchers developed a more precise screening index to identify areas with high levels of chronic lead exposure in children. The method uses established risk factors, including poverty and housing built before 1950, and can be applied to any area in the US.
A study published in Psychological Science reveals that enjoying a fearful experience, like a haunted house, requires finding the perfect balance of fear and enjoyment. The researchers found an inverted U-shape trend showing that too little or too much fear can decrease enjoyment, while just-right fear levels maximize it.
Emery N. Brown, a neuroscientist and practicing anesthesiologist, has won the SfN's Swartz Prize for his contributions to neural signal processing, anesthetic mechanisms, and statistical methods. His research advances neuroscientific understanding of how anesthetics affect the brain, improving patient care.
Dr. Zoellner received the Frozen Food Foundation Freezing Research Award for her work on agent-based computer models to control foodborne pathogens in frozen food facilities. Her research helps assure the microbial safety of frozen foods through the identification and tracing of Listeria monocytogenes.
A study published in Nature Metabolism found that high fat and low carbohydrate diets can completely prevent or even reverse heart failure caused by a metabolic process. The research team discovered that providing a high-fat, low carbohydrate diet can improve cardiac fat metabolism and prevent or reverse cardiac dysfunction.
Researchers have discovered a new understanding of how fruit flies perceive color by examining the spectrum of light they can see. The study found that the green photoreceptor's light sensitivity shifted significantly, with its original range now better suited for seeing orange rather than green.
Researchers have conducted the first operando stability study of high-purity BiVO4 photoanodes during photoelectrochemical oxygen evolution reaction (OER). Using in-situ plasma mass spectrometry, they determined a useful parameter called the stability number (S), which can be used to compare and assess the stability of photoelectrodes.
A randomized phase III trial found that stereotactic radiosurgery reduces cognitive decline without compromising survival for patients with four or more brain metastases. Patients who received SRS had better preserved cognitive function compared to those who received whole-brain radiation therapy.
Researchers are using a new technology to monitor the movement of thawing Arctic permafrost. A 1.5-kilometer fiber-optic cable will be turned into a long line of vibration sensors to collect seismic data and predict future behavior of the thawing permafrost.