Astronomers have long sought the launch sites for high-energy protons in our galaxy, and NASA's Fermi Gamma-ray Space Telescope has confirmed that a supernova remnant is just such a place. The shock waves of exploded stars boost particles to speeds comparable to light, producing a tell-tale glow in gamma rays.
Adults with vision or hearing disabilities have lower COVID-19 vaccination rates compared to those without disabilities. The study suggests that initiatives promoting equitable and accessible vaccination may be necessary to address these disparities.
A research team led by City University of Hong Kong discovered a new mechanism that increases both strength and ductility in high-entropy alloys. The findings provide insights for designing strong yet ductile materials and ceramics.
A new University of Washington study found that bird behavior was not significantly affected by the reduced human activity during COVID-19 lockdowns. In fact, many birds were observed in highly developed urban areas, suggesting that green spaces may serve as important refuges for urban birds.
Researchers developed a new cardiac cell-derived platform that closely mimics the human heart, accelerating maturation of human cardiac cells towards a state suitable for preclinical drug testing. The model achieved structural, mechanical, metabolic, and electrophysiological characteristics close to adult heart muscle within 30 days.
A systematic review of 284 studies on K-12 online education identified key elements for effective instruction, including teacher training, district access to technology, and consideration of student developmental level. The study also emphasized the importance of course design, community-building, and accessible learning resources.
Researchers at UC San Francisco have discovered how to shift damaged brain cells from a diseased state into a healthy one using CRISPR technology. The study found that reprogramming microglia cells can help remove protein plaques and protect synapses, potentially treating Alzheimer's and other forms of dementia.
A new study suggests that acetate produced by the liver diffuses into the intestines, supporting bacterial growth and causing imbalanced microbiota. This imbalance does not appear to play a major role in alcoholic liver disease risk.
Researchers developed an optical microscope to observe electron transfer in gold nanoparticles, providing a new strategy for studying photocatalysts at the single particle level. The technology enables selective induction of electron excitation and quantitative analysis of its effects on semiconductor photocatalysts.
Researchers developed a nanopore-scale glass-topped lab-on-a-chip to study complex fluid behaviors at the nanoscale. The device allowed for direct visual recordings of liquid to vapor and back to liquid phase changes, revealing that nanopore behavior influences production and affecting recovery discrepancies.
A large Canadian study published in The Lancet Infectious Diseases journal suggests COVID-19 mRNA vaccines are safe to use in pregnancy. Pregnant women who received the vaccine experienced lower rates of health events post-vaccination compared to non-pregnant vaccinated individuals.
A new study published in Diabetes Care has reported an increase in health inequalities among ethnic minorities with diabetes since the COVID-19 pandemic. The review highlighted structural barriers such as housing, education, and employment opportunities that put these individuals at greater risk of severe COVID-19 outcomes.
A research team used game theory to analyze cooperation in networks and found that networks with a high level of cooperation can emerge if individuals take a clear-cut position against free riders. The study also showed that if contributors leave an environment too quickly, it leads to a lower level of cooperation.
Engineers at RMIT University have created a sustainable concrete using 100% recycled tyre rubber, reducing environmental impact and manufacturing costs. The innovative material can be used in various construction projects, including low-cost housing.
A study published in Ocean & Coastal Management reveals that southern right whales are slower than expected at re-establishing a habitat in mainland waters. Social media posts and citizen scientist reports played a crucial role in assessing the species' population demographics, aiding conservation efforts.
Researchers found that two new techniques can help reduce needle fear in primary-aged children, including a distraction game and positive memory reframing. The study involved 41 children and showed promising results for broad vaccination programs.
Researchers at MIT discovered a peptide that sequesters heme, an iron-containing molecule, and sends bacteria into an iron-starvation mode, potentially treating diseases like periodontal disease and sickle cell disease. This finding could translate to therapeutic applications for patients with excessive heme in their blood.
Researchers developed a technology to overcome pore formation defects in CZTS thin-film solar cells, increasing power conversion efficiency. By changing metal deposition order, they suppressed large pores and improved the overall performance of eco-friendly solar cells.
Researchers found that Merkel cell carcinoma (MCC) Glypican-3 (GPC3) is expressed in nearly 70% of MCC tumors and up to 90% of MCPyV-negative cases. GPC3 expression is associated with worse prognosis, including increased risk of death from MCC. This makes GPC3 a promising target for chimeric antigen receptor T cell therapy.
A new study has identified the genes that become active in carotid arteries when plaque rupture causes a stroke. The researchers sequenced the RNAs in plaques from patients who had experienced a stroke within two to five days, revealing increased inflammation and loss of protective cap.
A small clinical trial found that OP-101 substantially reduced the risk of death and need for a ventilator in severely ill adults hospitalized with COVID-19. The treatment also showed significant benefits in decreasing biomarkers of inflammation and brain injury, suggesting potential for treating long COVID-related symptoms.
Researchers at the University of Cambridge discovered that nearly three-quarters of stem cell lines carry substantial DNA damage, which could compromise their use in research and cell-based therapies. The study found that whole genome sequencing is essential for confirming if cell lines are usable.
A study at Tulane University found that recently formed stroke plaques contain messenger RNA that causes inflammation and degrades a protective cap, leading to rupture. This discovery could lead to new tools to stop strokes from happening and develop new drugs or diagnostics to prevent heart attacks and strokes.
Researchers at Aarhus University have developed a new and inexpensive way to recycle polyurethane (PU) plastic by breaking it down into its original components. The method uses a simple chemical reaction involving alcohol, caustic potash, and an autoclave, making it cheaper and more scalable than previous methods.
A 3-dose Moderna COVID-19 vaccination schedule significantly improved SARS-CoV-2 antibody concentrations in immunocompromised patients. This improvement was comparable to those obtained by healthy individuals after the standard two-dose Moderna vaccination schedule.
Researchers have developed an interactive metabolic map of bio-based chemicals, providing a versatile tool for easy assessment and optimization of synthetic pathways. The map enables exploration and analysis of complex networks of biological and/or chemical reactions, facilitating the design and production of desired chemicals.
A study published in NeuroImage found that specific brain regions, including the superior frontal gyrus, play a crucial role in statistical learning. Weaker connections between these regions may actually enhance processing of novel information.
Researchers at The University of Queensland are working on a new treatment to reduce pain and debilitating side effects from chemotherapy in children. Dr Hana Starobova's research aims to prevent damage from cancer treatments, reducing the impact on children's quality of life. By studying Acute lymphoblastic leukaemia, the team hopes t...
New research reveals that social rejection can drive individuals to prioritize disease protection. When people experience social pain, they become more likely to take concerted efforts to safeguard against COVID-19. Conversely, when social interactions are less painful, people may be less vigilant in protecting themselves.
A recent study suggests that epigenetic information, normally reset between generations, is more frequently carried from mother to offspring than previously thought. This discovery could have implications for women with SMCHD1 variants and their children.
A recent study analyzed millions of SARS-CoV-2 genomes and found that recombination occurs more frequently in the spike protein region. The researchers developed a new software, RIPPLES, to detect this phenomenon, which is crucial for understanding the evolutionary history of the virus.
Hybridization between whiptail lizards leads to diverse evolutionary outcomes, including increased genetic diversity and creation of new species. A study reveals that only above a certain level of genetic distance does hybridization result in unisexual lineages, suggesting predictable outcomes.
A novel metaholographic platform has been developed to detect light exposure, addressing concerns about light damage to vaccines and other biomedical substances. The technology can be used in intelligent packaging and labeling to prevent counterfeits and verify authenticity of products.
Researchers at Tufts University School of Medicine suggest improvements to the release process and treatment for individuals with opioid use disorder (MOUD) who are transitioning from jail to the community. The study identifies three critical areas for improvement: bridge doses, better communication, and phone access.
A new study published in AJIC suggests that a combination of betadine and silver colloidal gel is more effective than either material alone for inhibiting the growth of common infection-causing bacteria. The findings could help medical professionals better treat and prevent serious infections in large wounds, including burns.
A comprehensive analysis of interstitial lung disease diagnosis and treatment in patients who received an antibody drug conjugate known as T-DXd found that close monitoring and proactive management can reduce the risk of ILD. The study results suggest that patient awareness and ongoing education can aid in early detection.
A new study found that human laryngeal anatomy simplification allowed for stable vocal folds and harmonic-rich sounds characteristic of human speech. This evolutionary adaptation enabled humans to produce a wide range of sounds, distinct from nonhuman primates.
A recent study published in Pediatrics found that neurologic complications are relatively common among children hospitalized with COVID-19, occurring in about 8% of cases. These complications can lead to life-altering conditions and increased hospital costs, highlighting the importance of vaccination and prevention strategies.
The new guideline provides evidence-based recommendations for managing patients on warfarin, DOACs, and antiplatelet drugs before and after surgeries. It aims to minimize preventable bleeding and thrombotic events by standardizing approaches and protocols.
Researchers tracked nocturnally migrating hawkmoths using tiny trackers, revealing they adjust flight headings in response to winds and terrain features. The findings suggest the animals use a combination of visual landmarks and Earth's magnetic field to navigate long distances during migration.
Engineers developed an algorithm to optimize individual turbine angles, reducing wake impact and increasing overall farm efficiency. This could lead to a significant improvement in existing wind farms' energy output and enable more turbines to be installed in tighter spaces.
Researchers from the University of Pennsylvania establish a relationship between topology and entanglement, tying two major principles in physics together. The connection reveals that the genus of the Fermi surface is closely related to a measure of quantum entanglement called mutual information.
A joint research team discovered a new genetic mutation related to intellectual disability, which affects the SlitTrack2 protein's function in forming excitatory synapses. The study found that mutations disrupt excitatory synaptic transmission and impair cognition in mice.
A new device replicates short sections of human blood vessels allowing for variable flow conditions that mimic the body. Researchers can now watch what's happening inside treated grafts down to individual cells.
Scientists have successfully engineered synthetic genetic circuits in Arabidopsis plants, allowing for the predictable alteration of lateral root density without affecting normal plant growth. This breakthrough enables future success in implementing combinatorial circuits in complex biological systems.
Researchers at UNSW Sydney have found a transposable element that regulates the immune response to virus infection in mice, leading to exaggerated immune responses and tissue damage. Reintroducing the element restores survival, suggesting its potential as a target for treatment.
A study comparing Ohio nature reserves and high-input agricultural lands found that nature reserves can store significantly more carbon. The researchers analyzed soil organic carbon storage, quality, and lability in these two types of land uses.
A study from the Alpha Generation Lab found that hyperactive children are more likely to use digital devices, while fidgety children may be more prone to social problems. The researchers suggest a two-way street where digital devices and behavior problems influence each other.
Researchers achieved a breakthrough in generating terahertz waves with a conversion efficiency of 0.35% using a dual-color femtosecond laser filamentation technique. The study investigated the influence of ambient gas species on THz generation efficiency and demonstrated improved performance in argon gas.
A new study finds that the drug terazosin has shown protective effects on motor neurons in models of motor neuron disease (MND), including zebrafish, mice and stem cell models. Researchers hope to launch a full clinical trial if the drug proves successful in a feasibility study involving 50 patients.
A study found that concurrent heat and drought events can have devastating effects on multiple sectors, including human health, energy, and agriculture. The research highlights the importance of considering compound extreme events in adaptation efforts to improve resilience.
The National Science Foundation has awarded Georgetown University $12.5 million to establish a collaborative institute focused on viral emergence and education. The Verena Biology Integration Institute aims to advance cross-disciplinary research and train the next generation of researchers in this field.
A new study found that even modest (1.6 C) climate warming causes reduced growth and increased mortality in northern conifer species, while broadleaved hardwoods may experience enhanced growth. The boreal forest's composition is likely to shift, potentially leading to a more impoverished version of the current ecosystem.
The US FDA is reassessing its need for animal tests in product development, exploring alternative methods that could improve efficacy and safety predictions. New technologies like microphysiological systems may replace traditional animal studies, enabling faster product approval.
The August issue of the CHEST journal features 47 articles on clinically relevant topics such as asthma, COPD, and pulmonary vascular disease. A highlighted article examines barriers to palliative care in interstitial lung disease.
A recent study published in PLOS ONE found that racial and ethnic minorities bore a disproportionate mental health burden during the COVID-19 pandemic. After controlling for various factors, Black participants were 1.16 times more likely to screen positive for depression, while Hispanic participants were 1.23 times more likely to do so.
Researchers found that adult female capuchin monkeys who are well-integrated into social networks with other females survive longer. In contrast, heterosexual relationships showed no survival-related benefits to females, but may still provide benefits for some individuals in specific circumstances. The study also reveals complex behavi...
The CHEETAH Center is a leading institution for HIV research, publishing over 300 papers on the virus's inner workings and potential treatments. Researchers are focusing on understanding HIV's life cycle, identifying key components essential for viral infection and replication.
Researchers at the University of Sussex have created an 'eternal engine' to keep next-generation atomic clocks ticking, enabling portable versions that can replace existing satellite navigation systems. The breakthrough uses microcombs and self-emergence technology to ensure stable operation in various conditions.
A recent study published in PLOS ONE found that opioid prescriptions declined for US patients with both cancer and non-cancer pain between 2012 and 2019. The proportion of people receiving any opioid prescription dropped from 49.7% to 30.5% for non-cancer pain and from 86.0% to 78.7% for cancer pain.