Researchers found that bacteria in tumors play a critical role in promoting cancer cell metastasis by modulating the cellular actin network and enhancing cell survival. This discovery could lead to new targets for preventing metastasis, potentially improving cancer treatment outcomes.
Rapidly growing market of antibiotic-free meat and poultry is threatened by lax labeling policies, warns a new study. Current authorization processes lack empirical testing, allowing antibiotics-treated animals into the supply chain, undermining RWA claims.
Researchers develop a new method to reconstruct the states of complex nonlinear systems based on time series data. The approach optimizes reconstruction parameters by focusing on the geometric structure of attractors, resulting in improved accuracy.
The American College of Cardiology is partnering with the Korean Society of Cardiology to host ACC Asia 2022 Together with KSC Spring Conference. The conference aims to critically examine emerging trends in cardiovascular care and share evidence-based strategies for improving heart health.
Astronomers have discovered the most distant galaxy candidate yet, named HD1, with a distance of approximately 13.5 billion light-years. If confirmed by observations with the James Webb Space Telescope, HD1 will be the most distant galaxy ever recorded.
A new breed of honey bees has been developed through selective breeding to resist the Varroa mite, a major threat to global honey bee populations. The 'Pol-line' bees showed a two-fold increase in colony survival compared to standard varieties, with significantly lower mite numbers and reduced viral transmission.
Researchers found that using indoor fans can increase the indoor temperature threshold before discomfort sets in by 3-4°C, reducing the need for air conditioners. The study also revealed a significant reduction in energy consumption and associated greenhouse gas emissions by up to 70%.
New research reveals that private protected areas (PPAs) are twice as likely to be in areas with human disturbance and three times more likely to protect key biodiversity areas. PPAs account for 1.2% of these areas, increasing connectivity by over 7%. This study highlights the importance of recognizing their role in conservation efforts.
Astronomers used over a decade of Fermi data to search for signs of long gravitational waves from supermassive black hole pairs. Although no waves were detected, the analysis shows that with more observations, these waves may be within Fermi's reach.
A new study published in Science Magazine found that nearly 42% of cattle destined for the 'Raised without Antibiotics' market have been treated with antibiotics, casting doubt on the accuracy of these labels. The research team suggests strengthening verification and enforcement to curb antibiotic use in food-animal production.
Researchers used mathematical modeling to characterize the interplay between immune suppression, immune blockade and antigenicity in pre-cancerous cells. They found that an immunosuppressive environment is crucial for colorectal cancer progression.
Researchers at KIST developed a bifunctional electrocatalyst with a staggered p-n heterojunction that significantly improves the rates of oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in zinc-air batteries. The technology utilizes solar energy, resulting in improved energy density and excellent cycle performance.
A new study from the University of Utah examines the impacts of decentralizing homeless service locations in Salt Lake County, Utah. The research found that people using the relocated resource centers tended to travel less, with visits to community services declining by as much as 40%.
A Norwegian University of Science and Technology study found that long-term follow-up and organized physical activity can reduce the risk of developing type 2 diabetes. Participants who engaged in healthier habits and increased activity saw significant improvements over five years.
A new study warns that California's water resilience planning may not be financially viable without careful partnership agreements, as benefits may not be evenly distributed among stakeholders. The research highlights the importance of considering multiple factors to construct investment partnerships that satisfy all partners.
The study found two DNA defense systems in Vibrio cholerae bacteria that work together to eliminate plasmids and prevent the spread of antibiotic resistance. These defense systems, called DdmDE and DdmABC, are encoded within distinct pathogenicity islands and help the bacteria survive pandemics.
Scientists at the University of Bath have developed a new technique called Transcription Block Survival (TBS) to accelerate the discovery of cancer-fighting drugs. TBS identifies molecules that can shut down dangerous proteins before they wreak havoc, by blocking their interaction with cell DNA.
A virtual cooking/nutrition program, Flint Families Cook, demonstrates success in reaching youth from low-income families and improving cooking self-efficacy and nutrition knowledge. The program encourages families to cook healthy meals together at home, using local ingredients.
A recent study published in mBio discovered that the SARS-CoV-2 viral gene ORF8 plays a crucial role in the severity and spread of COVID-19. Researchers found that mutations in ORF8 contribute to inflammation and disease outcomes, suggesting new treatment options for patients with severe cases.
Researchers discovered that the brain formats working memory representations into a shared, line-like shape. This finding suggests that the brain selectively stores relevant information while discarding irrelevant content, and has implications for our understanding of psychiatric and neurologic symptoms such as schizophrenia.
A team of scientists has developed a solar-powered water filter that can remove pathogens, pesticides, and micropollutants from contaminated water. The filter uses titanium dioxide (TiO2) nanowires and carbon nanotubes to produce reactive oxygen species that kill bacteria, viruses, and other microorganisms.
Researchers at UC Berkeley have developed a new material that can significantly reduce the energy required to control advanced silicon transistors. The engineered crystal composed of hafnium oxide and zirconium oxide achieves negative capacitance, which boosts performance by reducing voltage requirements.
Kaiyuan Yang's five-year grant will focus on enhancing the reliability and security of bioelectronic implants by making them aware of and adaptive to their physical and logical contexts. The goal is to develop WBMI bioelectronics that can be deeply implanted in humans through minimally invasive injection, ingestion or through vessels.
Researchers at Hokkaido University found that trimethylamine N-oxide (TMAO) can reversibly control the rigidity of kinesin-propelled microtubules, a crucial component of molecular machines. The study demonstrates a simple method to dynamically adjust MT property and functions.
Research by American Psychological Association suggests that people feel less vulnerable to COVID-19 when they think of their friends rather than strangers. This 'friend-shield effect' can lead to reduced safety precautions and increased infection risk.
Disparities in social determinants of health affect people with congenital heart disease, leading to unequal access to care. Strategies to address these issues include increasing specialist availability and improving telehealth capabilities.
A new study found that mountain streams are signaling climate change through changes in invertebrate populations, which can indicate ecosystem health. The researchers discovered that diversity tends to increase downstream but is lowest near lakes, highlighting the need for protecting these ecosystems from diversions and habitat damage.
A new study forecasts 1.4 million US street tree deaths from invasive insects by 2050, with the emerald ash borer responsible for most fatalities. Urban diversity can help mitigate this impact, and prioritizing management efforts like quarantining wood products may be necessary.
A Cornell study finds that children learn demonstratives like 'this' and 'that' at extremely young ages, even in languages with different structural systems. The research confirms that caregivers can expect children to start using these words between 12-18 months old.
A new study found that DNA evidence significantly improves prosecution outcomes, with 75% of cases with a match resulting in a guilty plea or trial. The study highlights the importance of quality forensic medical exams, DNA analysis, and prosecutor training to effectively use DNA evidence.
The UPV study uses AI to investigate subphenotypes in line with clinical characteristics, helping clinicians assess patients and plan resource allocation. The team develops predictive models for early mortality prediction and severity assessment, offering robust and reliable AI in data quality issues.
Research found that nearly half of heart disease patients have insomnia, which is significantly associated with recurrent heart events. Insomnia accounted for 16% of recurrent major adverse cardiovascular events in this study, suggesting that treating insomnia could reduce cardiovascular problems in these patients.
Scientists have discovered two complete ichthyosaur specimens from the Solnhofen area, preserving outer body shape and skin. The fossils, dated to around 150 million years old, provide new insights into the anatomy of these marine reptiles.
A new AI-based approach can predict cardiac arrest with significant accuracy, identifying patients at risk and predicting the likelihood of sudden cardiac death. The technology stands to transform clinical decision-making and increase survival rates from lethal arrhythmias.
A recent study published in ACS Omega analyzed protein levels in semen of men who recovered from COVID-19 and found significant reductions in sperm count, motility, and normally shaped sperm. The researchers also detected changes in fertility-related proteins such as semenogelin 1 and prosaposin.
Researchers at Brigham and Women's Hospital found administering medication abortion pills as early as possible is safe and may help determine ectopic pregnancy faster. However, patients may need to re-initiate treatment due to a higher failure rate when treated early.
Researchers used AI to analyze videos of over 2,500 ASL signs and found that challenging signs are made closer to the signer's face, making them easier for perceivers to recognize. This suggests that ASL has evolved to be more recognizable, improving communication.
Researchers found that mice with the Val89 gene variant exhibit attention deficit disorder-like problems, including diminished cognitive performance and increased vulnerability to distraction. The study provides direct evidence of the genetic variant's effects on acetylcholine availability and its resulting cognitive impacts.
An international team of researchers has identified 5,500 new RNA virus species that represent all five known RNA virus phyla. The study suggests there are at least five new RNA virus phyla needed to capture them and highlights the importance of marine microbes in ocean adaptation to climate change.
Australian researchers have discovered a new neurodevelopmental disorder linked to the tumor suppressor gene FBXW7. The condition causes mild to severe developmental delay, intellectual disability, and other symptoms, with genetic variations in this gene found in 28 individuals from 32 families worldwide.
In southern Anhui Province, archaeobotanical remains at the Jingshuidun site reveal early rice farming dating back to 4874-4820 cal. yr B.P., with millet cultivation emerging by 2667-2568 cal. yr B.P.
Researchers have discovered a potential new treatment for glioblastoma, which targets 'kinase' proteins to limit tumour growth and improve existing chemotherapeutic drugs. This breakthrough therapy may provide hope for patients with aggressive brain tumours, offering a more effective and sustainable approach to treatment.
The UGA team developed a rapid test for COVID-19 with high sensitivity and specificity, detecting the spike protein of SARS-CoV-2. The test has a detection time of less than 10 minutes and can detect all COVID-19 variants.
Geophysicists and computer scientists collaborate to better understand the dynamics of earthquakes and tsunamis. The team has identified three major characteristics that play a significant role in determining an earthquake's potential to stoke a tsunami, including stress along the fault line, rock rigidity, and sediment layer strength.
Adults who have used psilocybin are 30% less likely to develop opioid use disorder, according to a nationally representative survey. Psilocybin use is also associated with reduced symptoms of opioid dependence and abuse.
A Yale University study found significant racial and ethnic disparities in sleep duration, with Black people persistently reporting shorter sleep durations. The study highlights the need for renewed efforts to eliminate socioeconomic and health conditions that prevent minoritized individuals from achieving adequate sleep.
Researchers have created a virtual self-management tool called VMood to help reduce the community mental health gap in Vietnam. The app will link users with mental health resources and be available across the country, with support for community-based interventions for depression and anxiety.
A research team from City University of Hong Kong has developed an efficient electrochemical intercalation method to produce high-yield mono- or few-layer transition metal dichalcogenide (TMD) nanosheets. The new strategy offers a higher degree of control over lithium insertion and can be scaled up for industrial applications.
A triceratops specimen known as 'Big John' displays injuries to the skull that may have occurred during combat with another triceratops. The fossilized remains show signs of a traumatic injury and healing process, suggesting similarities between dinosaur and mammalian bone repair mechanisms.
A novel nuclear medicine combination therapy combining <sup> 177 </sup> Lu-PSMA-617 with idronoxil (NOX66) has been shown to be safe and effective in reducing PSA levels by over 50% in men with metastatic prostate cancer. The median overall survival was 19.7 months, suggesting potential for improved patient outcomes.
Engineers at University of California - Santa Barbara found that suspensions exhibit distinct behaviors when measured at varying scales. The study highlights the limitations of approximations and has industrial applications in manufacturing.
Researchers discovered that Viagra and a common over-the-counter drug TUDCA restored mitochondrial processes, which drive heart failure in HLHS patients. This could lead to new therapies for treating heart failure without relying on heart transplants.
Research reveals nearly a third of pregnant Medicaid beneficiaries screened for hepatitis C test positive, but fewer than a fifth receive follow-up care. A sustainable pathway to treatment is crucial, especially with expanded postpartum Medicaid coverage and highly effective oral medications.
A study of over 4,800 medical oncology practices found that Black patients had higher rates of chemotherapy-related emergency department visits and hospitalizations compared to white patients. The researchers developed reliable measures to assess these inequities, with potential for identifying high- and low-equity practices.
Researchers have made significant advancements in understanding the cellular level of ion channels, which are fundamental to sensing environmental signals. The discovery of fundamental ion-channel sensors for temperature and pressure has led to new treatments for conditions like stroke, hypertension, and Alzheimer's disease.
Naked mole-rats of higher social rank have a larger spleen, which may enable them to fight infections better and deal with inflammation more easily. The researchers also suspect that the spleen influences an animal's longevity, as successful naked mole-rats live longer.
New research uses surfboard samples to analyze seasonal changes in phytoplankton, a crucial component of ocean food chains. The study finds that phytoplankton levels nearshore and offshore are similar in autumn, winter and spring, but higher nearshore during summer months.
Research on strawberry extract consumption has shown potential benefits in delaying Alzheimer's disease progression. The study used Caenorhabditis elegans as a preclinical model, revealing that the Romina strawberry variety can delay beta-amyloid protein-induced paralysis and reduce amyloid-β aggregation.
Researchers have spotted the most distant astronomical object ever: a galaxy named HD1, 13.5 billion light-years away. The team proposes two ideas: HD1 may be forming stars at an astounding rate and possibly home to Population III stars or contain a supermassive black hole about 100 million times the mass of our Sun.
A modified version of the hormone kisspeptin has been shown to protect against the development of fat in the liver and reduce inflammation and fibrosis in a mouse model. This could potentially favorably impact the health and lives of millions of patients around the globe.