A $1.9 million NIH grant will support research on closing cellular gaps, with implications for wound healing and cellular regeneration therapies. The goal is to develop a theoretical understanding of the process, enabling control over individual factors and potential applications in regenerating heart cells.
New research reveals a dangerous combination of warming waters and nutrient overload is degrading freshwater ecosystem functioning. This simplification leads to shorter food chains and vulnerable top predators, emphasizing the urgent global need to reduce pollution levels.
A four-year study aims to understand the barriers faced by female Veterans experiencing homelessness, exploring data on demographics, housing history, and services accessed. The research will inform gender-specific interventions and guidelines for policy, practice, and care.
A new study by Ohio State University Wexner Medical Center found that probiotics can improve the immune system and behavior of both mothers and their offspring during pregnancy. Probiotics may also help counteract negative effects of prenatal stress, such as changes in brain inflammation and amino acid metabolism.
A Cornell University study finds that sleep resets vital brain function by silencing certain parts of the hippocampus, allowing neurons to reset and enable new learning. This mechanism could lead to breakthroughs in boosting memory and erasing negative memories in conditions like Alzheimer's disease and PTSD.
A recent study found that mechanosensitive protein polycystin-1 plays a crucial role in osteoclast-mediated bone resorption. The research team discovered that PC1 facilitates TAZ nuclear translocation, increasing the transcription of osteoclast-related genes and leading to decreased bone resorption.
Researchers developed a nanobody that targets V-ATPase c subunit and inhibits tumor cell invasion and metastasis. The nanobody was tested on 4T1-12B mouse breast cancer cells implanted in mice, where it showed effectiveness in preventing lung metastasis.
Researchers discovered a new type of brain activity called BARRs, which helps maintain balance in hippocampal neural networks during sleep. Disrupting these barrages can lead to impaired memory performance.
A study examining tecovirimat's effectiveness on mpox in the DRC found the drug safe but showed no significant impact on lesion duration. The trial, sponsored by the NIH and co-led with the DRC, resulted in lower mortality rates among participants compared to reported cases.
Researchers at Edith Cowan University have uncovered a significant genetic connection between Alzheimer's disease and several coronary artery disease-related disorders, offering opportunities to improve health outcomes. The study found that some of the same genes played a role in or are associated across these conditions.
Researchers at Yale University have discovered that brain cells begin to coalesce into wired networks during early development before experience has a chance to shape the brain. Cells that fire together wire together, and synchronization of their activity leads to strengthened associations, according to the new study published in Science.
Researchers developed a technique using videos and machine learning to quantify motor symptoms in early-stage Parkinson's disease. The approach achieved high accuracy in distinguishing between healthy individuals and those with early Parkinsonism, offering potential benefits for treatment outcomes.
Rice University professor Ashutosh Sabharwal leads a project to design and develop an open-access software-defined radio system for 6G wireless networking, imaging, and sensing. The system will support diverse bands and enable research communities to explore new directions in wireless technology.
Researchers at Texas A🏠M University School of Engineering Medicine have developed an innovative project to refine the skills of NFL officials through neuro-ophthalmologic training. The project uses 2D game data to create 3D simulations, enhancing training and on-field performance.
A mathematical framework reveals how the unobservable nature of effort and risk shapes research strategies and incentive structures. Scientists opt for safer projects that generate evidence of effort but hinder scientific progress.
Researchers at Singapore University of Technology and Design have developed a novel approach to metalworking using chitinous colloids and composites. By leveraging the affinity between chitin and metals, they created functional metallic structures without high temperatures or pressures.
A University of Gothenburg study found that work-related stress, particularly job conflicts and lack of influence, significantly increase the risk of future sick leave. Women who experienced these stressors were more than twice as likely to take sick leave, with adjusted factors indicating a significant impact on their wellbeing.
Researchers sequenced the complete genomes of Lyme disease bacteria representing all 23 known species, tracing the origins back millions of years. The study provides valuable tools and insights for combating the rising public health threat of Lyme disease.
A new study found that females' and males' muscles handle glucose and fatty acids differently, but regular physical activity cancels out these differences and triggers similar beneficial metabolic changes in both sexes. This research has important implications for preventing type 2 diabetes.
A nasal spray flu vaccine candidate developed by UW–Madison researchers has shown safety and potential to bolster protection against seasonal and pandemic influenza in vulnerable individuals. Administered alongside the annual flu shot, the vaccine may provide better protection for seniors.
Researchers at USC Dornsife introduce a new method to measure mercury released from permafrost, estimating the total amount awaiting release. The study finds that sediment samples provide a reliable measure of mercury content and offer deeper insight into the permafrost's hidden dangers.
A study published in JAMA Network Open found a significant association between cumulative adverse childhood experiences and adult household firearm ownership. Individuals with a history of abuse, neglect, or household dysfunction were more likely to own firearms as adults, possibly due to heightened vulnerability to physical violence.
Researchers have discovered that sunflowers wiggle to find patches of sunlight, forming a zig-zag pattern that maximizes access to light. This movement allows the plant to explore its surroundings and settle into configurations that provide maximum light exposure.
A uterus transplant was successfully performed on women with absolute uterine-factor infertility, resulting in a high live birth rate. However, the procedure was also associated with significant medical and surgical risks for both recipients and donors.
A new spatiotemporal fusion method, StarFusion, combines deep learning and traditional regression techniques to address the limitations of current fusion methods. It achieves high fusion accuracy while preserving fine spatial details, making it a valuable tool for crop monitoring and management.
Researchers developed a new theoretical modelling technique to study molecular junctions, enabling significant light emission and high harmonic generation. The symmetries in configuration can enhance or suppress certain light frequencies, making it suitable for switch or amplifier applications.
Researchers have discovered a new type of brain cell in the medial entorhinal cortex that accurately predicts future locations as an animal travels. This discovery helps explain how planned spatial navigation is possible and has important implications for understanding mechanisms of spatial navigation and episodic memory formation.
Researchers found that 49% of respondents experienced a moderate to extreme impact on their mental or emotional wellbeing after encountering negative experiences in virtual environments. The study highlights the need for metaverse companies to instill clear regulatory frameworks for safe virtual spaces.
A study analyzing 5.5 million EU/EEA infectious disease cases over 10 years found significant sex differences in notified male versus female cases for several diseases. The proportion of males ranged from 40-45% for pertussis and Shiga toxin-producing Escherichia coli infections to 75-80% for HIV/AIDS.
Researchers from the Linda Crnic Institute for Down Syndrome identified lower oxygen availability and dysregulated red blood cell function in individuals with Down syndrome. The study highlights potential targets for effective medical interventions to improve oxygen physiology in this population.
A study at UFSCar found that remote testing can be reliable for functional mobility and muscle strength, especially for those with dementia. This new methodology enables more frequent health sessions and better patient tracking.
A novel printing technique allows for the creation of thin metal oxide films at room temperature, resulting in transparent and conductive circuits that can function at high temperatures. The technique uses liquid metals to deposit two-layer thin films with remarkable stability and flexibility.
A new study reveals that zebrafish spinal cords regenerate by leveraging the survival and adaptability of severed neurons, rather than relying on stem cells. The research identifies genetic targets to promote this type of plasticity in humans and other mammals.
A new geospatial analysis reveals that only one-third of the world's population in low- and middle-income countries has access to safe drinking water, with fecal contamination affecting almost half. The study emphasizes the need for improved water quality monitoring and infrastructure investments to address this critical human right.
Researchers propose a leaf-inspired luminescent solar concentrator (LSC) design to overcome scalability limitations. The innovative setup enhances photon collection and transfer, improving efficiency and reducing self-absorption issues.
A recent study identified a protein named importin-7 (IPO7) as a carrier that transports flavivirus core proteins into host cell nuclei. The study found that IPO7 plays a crucial role in the efficient production of viral particles, even though initial replication was comparable between two cell types. Blocking this transport mechanism ...
A new study by Yale researchers suggests that long COVID has caused extensive work time loss for many Americans, with nearly 14% not returning to work within three months. The study also found that participants experiencing five or more symptoms were twice as likely to be out of work.
A new research project aims to create a highly effective and selective biological herbicide targeting Palmer amaranth. The researchers will use synthetic biology techniques to develop RNA molecules known as Ribozymes that can influence specific gene expression, eliminating the weed through a specific infection.
A new study suggests a mouthwash-based test can help physicians predict disease recurrence in head and neck cancer patients by detecting biomarkers in saliva. Elevated levels of CD44 and total protein were associated with increased recurrence risk, highlighting the potential for early detection and reducing morbidity and mortality.
A new study found that bone fracture rates in older women differ dramatically by race, with White women having the highest risk. Hispanic women had a lower risk of 10%, while Asian-American women experienced varying fracture rates depending on their ethnicity. The study highlights the need to better understand factors behind these diff...
Researchers discovered that blocking Cxcr4 in mice reduced white fat tissue, while estrogen therapy could be effective with lower doses. The study offers promising avenues for understanding healthy and unhealthy fat tissue development.
The new journal aims to promote and lead the development of disciplines with cutting-edge scientific research on food and medicine homology. It focuses on how various foods can provide benefits beyond just satisfying hunger, from nutritional support to therapeutic effects.
Scientists at deCODE genetics have discovered rare sequence variants in ITSN1 linked to Parkinson's Disease. These variants may contribute to disease pathogenesis through CDC42 dysregulation and dopaminergic neuron degeneration.
Researchers develop a modular approach to scaling quantum processors using semiconductor technology and long-distance entangling links. This enables the creation of small arrays of qubits that can be connected to form larger systems, overcoming challenges in controlling individual qubits and maintaining coherence.
The International Space Station National Laboratory is collaborating with NASA to fund up to $4 million in research addressing significant diseases like cancer, cardiovascular disease, and neurodegenerative disease. The joint solicitation aims to leverage microgravity to improve existing or develop new technologies for health problems ...
A genetic analysis of Lyme disease bacteria has created a powerful resource for identifying specific bacterial strains, enabling more accurate diagnostic tests and treatments. The study reveals how these bacteria evolve and exchange genetic material, providing insights for predicting and responding to changes in their behavior.
The brain stores multiple copies of a single memory in parallel among different groups of neurons emerging at different stages during embryonic development. These memory copies change with time, with early-born neurons storing long-term persistence and late-born neurons fading over time.
Researchers successfully restored the brain's waste-clearing process by reviving cervical lymph vessel function in aging mice, utilizing a known drug to boost efficiency. This breakthrough could pave the way for future therapies targeting neurodegenerative diseases.
Researchers found the US can meet its entire seafood demand through domestic production, but current exports and imports limit self-reliance. Increasing consumption of lesser-exported species like herring and anchovy could strengthen the domestic supply and contribute to a more sustainable food system.
A new study reveals that the selection of paleoclimate data significantly impacts global temperature reconstructions during the Common Era. Researchers found that non-tree-ring proxies show stronger cooling trends, suggesting uncertainties in proxy records affect climate understanding.
Researchers found that omega-3 fatty acid EPA can rescue changes caused by saturated fats in cardiomyocytes, indicating a potential protective effect on heart health. The study highlights the importance of dietary choices in preventing arrhythmias.
Researchers at UTEP will investigate how stress from nicotine withdrawal is intensified by ovarian hormones in women, aiming to develop more effective treatments for women experiencing severe nicotine withdrawal symptoms. The five-year study will also explore the impact of e-cigarette use on adolescent females.
A new algorithm developed at Washington State University improves safety and efficiency in robots working with humans by accounting for human carelessness. The tool has shown a maximum improvement of 80% in safety and 38% in efficiency compared to existing methods, and the researchers plan to test it in real-world settings.
Researchers found that HIV-infected individuals with impaired immune recovery (INRs) have significantly higher expression of IFI27 and IFI6 in their peripheral blood compared to those who recovered well (IRs). A predictive model using these genes, along with age and CD4+ T/CD8+ T ratio, accurately identified INRs. These findings sugges...
Researchers at Arizona State University have introduced a new sterilization technique using X-ray irradiation to reduce Aspergillus flavus viability in contaminated corn. The method stops the fungus from transmitting spores and producing aflatoxins, crucial for developing additional remediation techniques.
A study of 13,084 adults with iron deficiency found that 42% had normal iron levels within three years, while 58% continued to have low ferritin levels. Factors associated with faster resolution included older age, male sex, and Medicare insurance. Persistent delays in treatment highlight the need for improved recognition and efficient...
Researchers develop classical electrical circuit to generate system with negative entanglement entropy, shedding light on complex phenomenon. The experiment provides insight into Non-Hermitian systems and their properties.
Researchers develop film-balloon (FiBa) soft robots with novel fabrication approach, enabling lightweight, untethered operation and advanced biomimetic locomotion capabilities. The breakthrough enhances the operational capabilities of soft robots for diverse applications.
Researchers have developed a technique to image magnetic structures in micrometer-thick magnets using coherent X-ray phase dichroism. This enables the study of previously inaccessible 3D textures in chiral magnets and giant magnetofossils, opening new avenues for spintronics and rock magnetism research.
A new Australian study reveals that people experiencing homelessness face constant and intrusive police interactions, leading to feelings of intimidation, harassment, and stigma. The research highlights the need for improved social security nets, community support services, and public housing infrastructure.