Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
A team of researchers led by Texas A&M University has discovered Atlantic herring possess exceptionally high diversity in their MHC class II genes, a group of immune genes involved in recognizing pathogens. This diversity is shaped by natural selection driven by the evolutionary
Researchers have developed an ultracompact gene activation tool called TIGRa, which can target multiple genes simultaneously and is smaller than CRISPR-based tools. TIGRa was tested in a mouse model and showed promising results in treating retinal degenerative conditions, including glaucoma.
Researchers at Yale University have discovered two ancient, extinct giant tortoise lineages using a new combination of computational tools. The findings can aid conservation efforts in the Galapagos archipelago by unlocking the genetic diversity of extinct species.
SourceYale University·JournalProceedings of the Royal Society B Biological Sciences
Researchers developed new guidelines to study molecular biomarkers associated with stroke recovery. The recommendations aim to identify biological signals that can help clinicians determine the most effective therapies for each patient at the right moment. The guidelines also emphasize the importance of creating national biomarker cent...
Researchers discovered how tumors interact with the body to grow and spread, revealing a new target for cancer therapy. Metadherin, a protein encoded by the MTDH gene, mediates this metabolic-immune crosstalk, supporting tumor growth and metastasis.
Researchers at Texas A&M University are working on a project to develop a mobile and efficient drilling system that combines faster drilling technology, real-time rock analysis, and artificial intelligence to identify valuable minerals in real time. This project aims to reduce the time needed to evaluate potential deposits of rare eart...
The researcher will investigate how infected cells live and die, and what chemical signals they release to surrounding cells. This work could lead to better antiviral drugs and virus-based cancer treatments.
A new Concordia study suggests that reducing fast fashion's environmental impact can be achieved through changes in manufacturing, transportation, and consumer use. By producing fewer garments, designing them with longevity in mind, and cutting back on air freight, the fashion industry can achieve significant environmental benefits.
Researchers developed SOT-MRAM, a fast and energy-efficient memory tech, to address AI's increasing energy needs. The technology can reduce energy consumption by up to 5x, making it suitable for edge devices and applications where power is limited.
A new study identifies a distinct population of lung vein cells that contribute to scar tissue formation, a process known as fibrosis, in diseases like pulmonary fibrosis. The researchers found that targeting a specific signaling pathway can prevent lung scarring and inflammation.
A new study found that nearly 20% of eligible adults in Medicaid expansion states are at risk of losing health coverage due to insufficient or inconsistent work hours. Women, unmarried people, and those with limited education are disproportionately affected.
Two new research chairs at UVic will focus on improving climate-ready ocean stewardship and prevention-focused health research. Elliott Hazen will lead efforts to identify early ecosystem warning signals and collaborate with Indigenous communities to support climate-responsive ocean stewardship. David Almeida will establish a digital a...
A new study from the University of Georgia found that Joro spiders eat different insects and a wider variety than native orb weavers, suggesting they don't compete for food. However, Joros are still taking up physical space, but can often be found alongside native spiders in their webs.
Cyclin D1, a protein linked to cancer, paradoxically promotes chronic inflammation in non-proliferating senescent cells, which can lead to age-related disease. Research suggests that targeting cyclin D1 may be a promising strategy to reduce inflammation and promote healthier aging.
A new theranostic pair, 68Ga/177Lu-NYM096, shows excellent tumor uptake in clear cell renal cell carcinoma lesions and demonstrates early evidence of tumor response in patients. The radiotracer can identify tumors and deliver targeted radiotherapy, mitigating toxicity issues common with treatment.
A warming tropical pool has temporarily slowed Antarctic ice loss by triggering a Rossby wave train and reorganizing moisture transport, resulting in a 695 billion-ton mass gain. This phenomenon, linked to tropical warm-pool warming, demonstrates the complex interactions between atmospheric circulation and ice sheet mass changes.
The American Academy of Neurology launches BrainHealth.com, a public resource providing expert-reviewed information, tools, and stories for brain health. The website offers evidence-based guidance and practical resources for individuals to make informed choices for their brain health at every stage of life.
Thomson Reuters developed a frontier AI model named Thomson that rivals big foundation models with a $40 million development cost. The approach allows organisations to build and deploy frontier AI systems without major frontier labs' resources, addressing governments' and companies' need for sovereign AI systems.
Researchers found that impaired peroxisomal function can increase insulin secretion while promoting insulin oxidation and disrupting pancreatic beta cell maturity. Healthy peroxisomes play a role in protecting insulin from oxidative modification and degradation, and helping beta cells maintain their specialized characteristics.
Researchers are studying the male role in early pregnancy loss, focusing on paternal epigenetics and its impact on fertility and pregnancy. By analyzing sperm from bulls with high and low fertility, the team aims to understand how nongenetic changes to DNA affect embryo development and gene regulation.
Researchers have created a high-resolution functional map of human immune cells, revealing intricate circuits that govern health and disease. The dataset provides a powerful framework for designing cancer immunotherapies and treating autoimmune conditions, and serves as a foundation for AI models of biology.
Researchers developed fluorescent molecules that allow imaging of DNA inside living cells at unprecedented resolution, and in preserved cells, close to the width of the double helix. The team tested the probes on cancer patients and found DNA to be noticeably looser and more spread out in tumours.
Researchers have mapped how the immune response in people with sepsis changes over time, revealing three distinct immune states. This finding could lead to targeted treatments for sepsis patients, as the immune state doesn't match the clinical stage of sepsis.
Digital tools are transforming clinical research, public health readiness, healthcare institutions, and consumer choices. Citizen science initiatives using mobile apps are also growing, with three types of citizen science identified: with-the-people, by-the-people, and for-the-people.
Researchers have identified a subset of B cells known as atypical memory cells as the primary precursors of autoantibody-producing cells during SARS-CoV-2 infection. These cells adopt a markedly different biological program, leading to increased autoantibody production. The study provides new insight into how viral infections can trigg...
A study found that higher breastfeeding intensity is associated with more favorable early postpartum lipid profiles among women with prior gestational diabetes. Greater breastfeeding intensity may be linked to a more favorable early cardiometabolic profile in these women.
A team led by Professor Paulin Straughan is studying how urban design and infrastructure influence physical activity, mobility, and social participation among older adults. The goal is to create a sustainable approach to wellbeing-management through
A new generation of intelligent decision support methods and software tools will be developed to enhance supply chain resilience, optimize healthcare operations, and strengthen emergency response coordination. The HOPE project aims to create a lasting area of excellence in human-centered AI, serving as a trusted partner for government,...
A recent study aims to evaluate the effectiveness of Healthier SG in cancer screening, focusing on improving systems and boosting habits. The research seeks to address knowledge gaps in evidence-based planning for Singapore's preventive care agenda.
Researchers found that reef fish exposed to motorboat noise as embryos and juveniles grow smaller and have impaired survival skills. The study suggests that limiting motorboat traffic near reefs during breeding season may help preserve coral reefs.
Researchers developed a Mo alloy with high strength, good ductility, and excellent thermal stability at high temperatures, overcoming conventional dispersion-strengthened Mo alloys' limitations. The alloy retained stable mechanical properties after long-term annealing at 1000 °C.
Kajetan Fijalkowski developed a method for determining electrical resistance without an external magnetic field, opening up new possibilities for future measurement systems. This achievement contributes to the foundations of metrology and has implications for linking different electrical units.
A new study from the University of Copenhagen and Nordsjællands Hospital found a 75% reduction in hospital admissions among infants aged 0-5 months in Denmark following the rollout of an RSV vaccine for pregnant women. This significant decline suggests that the vaccine is effective in reducing the burden of severe RSV disease.
Researchers from the Max Planck Institute for Solar System Research have determined Mercury's surface silicon dioxide content with greater accuracy, finding it up to 25% less abundant than previously thought. This suggests the volcanic rocks on Mercury formed from more deeply melted mantle material than previously assumed.
Researchers at Ludwig-Maximilians-Universität München identify a molecular mechanism enabling single-celled parasites to move and invade host cells through lysine methylation. This regulatory layer connects signaling, cytoskeletal activation, and mechanical force, offering a promising starting point for drug development.
Researchers developed a plyometric-based high-intensity interval training (Plyo-HIIT) program to preserve muscle while reducing fat in children aged 9-12. The 16-week program showed promise in improving muscle-to-fat ratio, prioritizing metabolic health over weight reduction.
Researchers have developed a programmable directional photonic spiking neuron based on a non-Hermitian silicon microresonator. The device, called DRUM, can emit spikes in one direction while remaining inactive in the other, reducing unwanted crosstalk and enabling true directional interaction.
The Plant Journal has transitioned to gold open access, removing paywalls and making its research freely available. This change is part of the Society for Experimental Biology's strategy to support the plant science community and ensure discoveries reach the widest audience.
Researchers developed a new approach to multi-camera identity tracking by combining camera geometry and visual appearance. The method achieved high IDF1 scores on benchmarks, demonstrating improved tracking continuity across different environments, but highlighted limitations in detecting people in severe occlusion.