Stuart Dryer, a University of Houston biology professor, has been awarded the prestigious AAAS Fellowship for his work in molecular physiology and ion channel regulation. His research on ion channels could lead to new treatments for cancer, asthma, and kidney diseases.
Researchers are working with commercial fishermen to track monkfish migration patterns using electronic tags implanted under the skin. The study aims to improve understanding of the fish's biology and behavior, including its age and growth rate, as well as its interaction with ocean currents and tides.
A recent study published in Molecular Biology and Evolution found that sexually reproducing organisms accumulate fewer harmful DNA mutations than asexually reproducing ones. This suggests that sexual reproduction provides a protective advantage against genetic damage.
Researchers at UC San Diego successfully synchronized bacterial genetic clocks to blink in unison and alter their blinking rates in response to environmental conditions. The achievement is a crucial step towards creating genetic sensors that can monitor temperature, poisons, and other hazards.
Scientists at EMBL discovered membrane-coat proteins in bacteria from the PVC superphylum, which could aid in understanding eukaryotic cell evolution and structure. These findings provide molecular evidence that coat proteins shape eukaryotic endomembrane systems in prokaryotes.
The BIOFAB facility aims to produce thousands of standardized DNA parts, shortening the development time and lowering the cost of synthetic biology for academic or biotech laboratories. The project will enable researchers to mix and match genetic parts in synthetic organisms to produce new drugs, fuels, or chemicals.
Researchers utilize zebrafish to study human cancer, leveraging transplantable tumors, genetic models, and transgenic fish to understand tumor development and metastasis. The special issue presents innovative approaches for modeling human cancer in zebrafish.
Researchers investigated over 300 proteins in axolotl limbs, discovering key proteins involved in cell reprogramming and avoiding cell death. These findings may contribute to a better understanding of limb regeneration and potentially lead to new treatments for human amputations.
James A. Wells, a UCSF professor and director of the small molecule discovery center, has made groundbreaking contributions to protein engineering and discovery. He integrates multiple disciplines to design molecules that selectively activate or inhibit cellular processes.
Researchers at Brown University have identified a cellular mechanism that enables cells to transform their state, which could lead to new insights into diseases. The study found that a regulatory protein removes a lid from genes, allowing the cell to change its identity.
The 'Immune Attack' video game increased teenagers' understanding of cell biology and molecular science, according to a study. Players navigated the microscopic world of immune system proteins and cells to save a patient with bacterial infection, measurably improving their knowledge.
A new game called Immune Attack teaches 7th-12th graders about immune system proteins and cells. The game shows significant gains in confidence and knowledge among players, according to an FAS expert. The game is designed to inspire high school computer programming classes to create their own games.
A Scripps Research Institute team restored partial function to lung cells collected from patients with cystic fibrosis, opening a door to new therapies for this and other chronic diseases. The breakthrough uses a compound called suberoylanilide hydroxamic acid (SAHA) to correct protein misfolding.
Researchers describe molecular anatomy of Mycoplasma pneumoniae, a small bacterium that can survive on its own. The study reveals intricate networks and multifunctional molecules, challenging the idea of a 'minimal' cell.
Researchers from UC San Diego used a systems biology approach to determine how core biochemical pathways are altered in skeletal muscle cells and fat cells in people with insulin resistance. The study found that common drugs for treating insulin resistance, such as TZDs, alter these pathways, leading to improved drug therapies.
Researchers have developed a cutting-edge approach to understand the 'histone code,' determining why genes function differently in various cells. The new method offers unprecedented insight into stem cells, cancer, and other fundamental biological processes.
Phillip A. Sharp has been awarded the 2010 Herbert Tabor Lectureship for his groundbreaking research on small RNAs, RNA interference, and its potential to revolutionize biology and generate new therapeutics. Sharp's work builds on his landmark discovery of RNA splicing in 1977, which earned him a Nobel Prize in Physiology or Medicine.
Keystone Symposia has received a three-year, $2.7 million grant from the Bill & Melinda Gates Foundation to support global health conferences and provide travel awards to scientists from developing countries. The funding will also enable the organization to expand its conference program with new topics and locations.
The American Society of Plant Biologists has launched 'Teaching Tools in Plant Biology' in The Plant Cell, a monthly online feature with regularly updated sets of teaching materials on important themes in plant biology. Peer-reviewed tools are designed for upper-level undergraduates but can also be adapted for introductory courses.
EMBO has elected 66 top-life scientists with expertise in various molecular biology fields, including evolutionary and computational biology. The new members come from 16 countries and include 15 female researchers recognized for their contributions to life science research.
A study published in the Journal of Cell Biology reveals that PIKfyve, a lipid kinase, protects neurons from calcium overload by degrading voltage-gated calcium channels. This mechanism may provide new insights into neurodegenerative disorders such as stroke, Parkinson's disease, and Alzheimer's disease.
The M.D. Anderson team will use a systems biology approach to analyze multi-gene pathways and combinations of pathways in cancer. The goal is to generate molecular portraits of cancers to personalize therapy choices and improve cancer risk assessment.
A three-year, $2.4 million grant will develop a systems biology approach to combat the effects of drought on staple food crops like maize, wheat, and rice. The project aims to identify key regulatory genes and signaling pathways that can improve drought resistance.
Researchers at Rothamsted Research and Birkbeck University use Diamond Light Source's X-rays to unravel the mechanisms linked to pheromone detection in silkworm moths. This breakthrough has significant implications for developing new eco-friendly pest control methods, which could also benefit biosensors and detect explosives.
The Wilson Center's Synthetic Biology project has received two National Science Foundation grants to support research on the implications of synthetic biology for sustainability science and policy. The projects will explore emerging issues in synthetic biology, including its potential contribution to sustainable development.
Stem cell biology faces challenges in defining molecular characteristics, with potency and self-renewal not exclusive to stem cells. A new perspective suggests considering 'stemness' as a system property, rather than individual cell traits, which may lead to improved understanding of cancer stem cells.
Researchers used light-activated proteins to pinpoint the neural cell responsible for a specific behavior in zebrafish, a breakthrough that could lead to new insights into biological systems and synthetic biology applications. This technique may also aid in optimizing biofuels and disease-fighting therapies.
A team of researchers led by UIC's Mary Jo LaDu will examine the biology of apolipoprotein E and its receptors in the central nervous system. The $10M grant aims to understand the progression of Alzheimer's disease.
The National Science Foundation has awarded a grant to develop GenoCAD, a web-based Computer Assisted Design environment for synthetic biology. The platform allows users to design complex DNA sequences in minutes and will support teams of undergraduate students enrolled in iGEM.
K-State's Research Experience for Undergraduates program is one of the longest running in the country, providing students with independent research projects on ecology and evolution. The program aims to study the biota of the tallgrass prairie and its implications for global change.
Scientists at the University of Toronto's Department of Ecology and Evolutionary Biology discovered a novel gene, Ultrabithorax, responsible for water striders' unique body form. The gene lengthens mid-legs while shortening hind-legs, allowing water striders to glide on water.
Researchers at EMBL have identified a whole family of proteins capable of directly responding to the alarm signal produced by PARP1 when DNA is damaged. Histone macroH2A1.1 plays a key role in this process, condensing chromatin around damaged areas to increase repair chances.
The National Cancer Institute has named Emory University's Chemical Biology Discovery Center as part of an 11-member national consortium aiming to develop innovative targeted cancer therapies. The consortium will focus on unmet medical needs, including drugs with significant clinical promise.
The Systems Biology Graphical Notation (SBGN) is a new visual language for graphically representing biological information, aiming to make complex models accurate, efficient, and easy to understand. Developed by researchers worldwide, SBGN will benefit systems biologists working on various biochemical processes.
The Systems Biology Graphical Notation (SBGN) provides a standardized visual language for representing biological information, making it easier to exchange complex information. The new standard will benefit systems biologists working on various biochemical processes, including gene regulation, metabolism, and cellular signaling.
Burnham will partner with NCI and private-sector companies to translate basic research into new cancer treatments. The consortium aims to accelerate the development of innovative therapeutics for high-risk areas of cancer biology.
Researchers have gained in-depth knowledge of pyruvate carboxylase's structure, a metabolic enzyme linked to genetic diseases like lactic acidaemia and hypoglycaemia. The study also sheds light on its potential role in obesity and diabetes treatments.
Researchers highlight algebraic models as a crucial tool for undergraduate biologists, allowing them to integrate mathematical modeling into their coursework. These models focus on the logic of network connections, making them accessible to students with limited mathematical background.
A new study published in the Journal of Leukocyte Biology found that zinc activates a key protein on T cells needed to fight infections. Zinc supplementation has been shown to reduce the duration and severity of various illnesses, including childhood diarrhea and lower respiratory infections.
This special issue of DNA and Cell Biology delves into the complexities of symbiosis, revealing how microorganisms adapt to changing environments and host responses. The issue highlights various studies on bacterial interactions with their hosts, exploring mechanisms of adaptation and functional plasticity in constrained mutualisms.
Researchers created 'bacterial computers' that can solve complex mathematical problems, such as the Hamiltonian Path Problem and Burnt Pancake Problem. The innovation uses synthetic biology techniques to enable living cells to perform calculations, opening up new applications for biology and mathematics.
SRI International was chosen to lead three research and development centers in the NCI's Chemical Biology Consortium program. The goal of the program is to discover and develop new cancer therapeutics against novel molecular and genetic targets.
Researchers advocate for systems biology in cancer treatment, promising improved diagnostic tools and new drug targets. The approach integrates mathematical modeling, simulations, and experiments to understand complex cancer processes.
Researchers discuss how physics is changing our understanding of cells, brain function, and the potential role of quantum mechanics in biology. Paul Davies suggests that fundamental quantum processes could be key to understanding life's origins.
Researchers at the University of Nottingham have identified gibberellin as a hormone controlling plant root growth by regulating cell proliferation and expansion rates. The study highlights the importance of understanding hormone regulation in plant biology for improving crop yields.
Researchers have discovered that two commercially available drugs used for Parkinson's treatment, entacapone and tolcapone, have potential to treat multi-drug resistant tuberculosis. The study, published in PLOS Computational Biology, uses a novel computational strategy and experimental validation to support this repositioning.
Researchers have produced video footage of a male nematode worm preparing to mate with a hermaphrodite, showcasing the complex process. The study revealed that the male uses acetylcholine to regulate tail muscles for an exploratory embrace, and then searches for the vulva before mating commences.
Scientists at the University of Gothenburg have discovered a 'water gate' in yeast cells that regulates water flow, which may lead to new cancer drugs. The discovery has potential applications in human cancer research and could result in inhibitors for human aquaporins.
Four University of Miami Marine Biology and Fisheries students have received recognition from the National Science Foundation for their research on coral reefs. Ross Cunning and John Parkinson were awarded fellowships, while Sean Bignami and Kevin V. Brix received Honorable Mentions.
Scientists have identified distinct genes responsible for the evolution of pelvis and body armor loss in two species of stickleback fish. The study, published in Current Biology, shows that different genes can have similar effects on evolutionary change, contradicting earlier research.
Joseph Felsenstein and Louis J. Gross, both Central High graduates, received the 2009 and 2006 AIBS Distinguished Scientist Awards for their significant scientific contributions to integrative and organismal biology.
A new paper reveals that there are more genetic differences between humans and mice than previously thought. One-fifth of mouse genes are new copies that have emerged in the last 90 million years of mouse evolution.
The American Institute of Biological Sciences (AIBS) recognizes Joseph Felsenstein, Robert T. Pennock, Bruce Alberts, Michael Pollan, Rita Colwell, and Chip Rowe for their significant positive contributions to the field of biology. The awards are presented to individuals who have made substantial scientific or educational impact.
Researchers have identified a new prognostic factor in breast cancer patients, predicting early disease recurrence, metastasis, and patient survival. The absence of caveolin-1 in the stroma is strongly associated with more aggressive disease and reduced progression-free survival.
A study published in the Journal of Cell Biology reveals that a mutated Alzheimer's-related protein called presenilin helps form and maintain nerve cell connections. The findings suggest that failing nerve transmission might be an early step in the disease's pathology.
A University of Minnesota study found that high school biology teachers significantly impact college students' acceptance of evolution and questioning of creationism. About two-thirds of students reported their high school classes included evolution, while one-third did not cover either evolution or creationism.
Gary Borisy, MBL director and CEO, has been elected to the National Academy of Sciences for his distinguished contributions to cell biology. He is a pioneer in the field, having discovered protein tubulin and provided insights into chromosome movement, cell motility, and microtubule dynamics.
Researchers have constructed a systems biology map of iron metabolism, a crucial process in animal cell survival. The study aims to improve our understanding of iron regulation and its potential manipulation for therapeutic benefits.
A team of Boston University researchers has developed a new method for engineering genetic circuits using combinatorial libraries and computer modeling. This approach enables the rapid construction of gene networks with predictable behaviors, accelerating synthetic biology research. The technique involves creating libraries of diverse ...
A recent study has found that the Humanin peptide protects against neuronal cell death and regulates insulin metabolism, significantly improving glucose levels in diabetic rats. The discovery provides new insight into the role of the brain in glucose metabolism and suggests a potential therapeutic approach to diabetes.