Researchers identified CEACAM6 as a key factor blocking the effectiveness of adenovirus-based therapies in treating cancer. Knocking down CEACAM6 expression increased anticancer effects in mice with human tumor cells.
A new study by OHSU School of Dentistry found that patients with self-ligating orthodontic brackets retained significantly fewer oral bacteria in plaque compared to those with elastomeric brackets. The researchers also developed a rapid and reliable method for quantifying oral bacteria using ATP-driven bioluminescence.
A new study from Ohio State University found that home tooth bleaching products reduce enamel hardness by 1.2-2 nanometers, affecting its ability to bounce back after force. Researchers suggest reformulating products to minimize side effects.
Researchers found that drinking white wine can lead to darker tooth stains due to acids creating rough spots and grooves. Red wine still causes more severe staining than white wine, but a whitening toothpaste can help prevent both types of stains.
Dr. Mirela Shinohara, a young researcher from Brazil, has been awarded the 2009 Toshio Nakao Fellowship by IADR. The fellowship supports her training and experience in dental materials science at a center of excellence. IADR is a nonprofit organization dedicated to advancing research and improving oral health worldwide.
A team of scientists led by Dr. Michael Walter discovered that WDR36 gene variations affect cell function only when combined with changes in another gene, STI1. This finding explains why some people with WDR36 gene variations get glaucoma while others don't.
Dr. Philippe Hujoel, a professor at the University of Washington School of Dentistry, is recognized for his outstanding achievements in behavioral science and health services research. He has published over 70 peer-reviewed papers on periodontal disease processes and oral-healthrelated quality of life.
Dr. Pamela DenBesten, UCSF professor and chair of Pediatric Dentistry, is recognized for her significant contributions to pulp biology and regeneration research. Her studies on the role of matrix molecules in cellular signaling have highlighted key bio-active molecules in regenerative events.
Three researchers have been awarded $75,000 grants to develop novel treatments for periodontal diseases, including a peptide-based hydrogel for dentin-pulp complex regeneration and an optical coherence tomography device for non-invasive diagnosis. The awards aim to improve oral health worldwide through innovative technologies.
Researchers at NYU College of Dentistry have been awarded a five-year grant to investigate the cooperative interactions between HIV viruses that aid in replication and disease persistence. The team aims to understand how these interactions speed up virus evolution, which could lead to new ways of slowing or stopping HIV replication.
A new Clinical Research Chair in Transplantation has been established at the University of Western Ontario to improve organ transplant outcomes for patients like Pat Davis, who received a kidney transplant after being told it was impossible.
A recent study published in General Dentistry suggests that childhood chicken pox caused by varicella zoster virus can lead to osteonecrosis of the jaw, a condition characterized by severe bone damage and tooth loss. The virus may also cause vision loss and other oral health problems if activated decades later.
A study published in General Dentistry has found that the VELscope device can detect oral HPV lesions, allowing for early detection and treatment of oral cancer. Regular dental check-ups and screenings are crucial in preventing and detecting oral cancer.
A new classification system aims to provide a more accurate picture of a patient's health issues, complementing body measurements. The Edmonton Obesity Staging System has five stages, from stage 0 to stage 4, and offers specific treatment approaches for each stage.
The European Academy of Dental and Maxillofacial Radiology has established 20 'Basic Principles' for safe use of Cone Beam Computed Tomography (CBCT) in dentistry. The guidelines cover areas such as justification, optimization, and training to protect patients from excessive radiation.
A recent study found that eating fast food more than twice a week negates the protective effects of breastfeeding on asthma in children. The research suggests high fat and salt content in fast food may contribute to increased asthma risk. Long-term breastfeeding duration also appeared crucial for reduced asthma risk
A study by the University of Rochester School of Medicine and Dentistry found that basic science research requires significant institutional support. The study calculated the total expenses for 25 new faculty members and found a shortfall of $39.9 million, requiring additional funding from other sources.
Researchers at OHSU School of Dentistry have discovered a novel function of Nerve Growth Factor in the development of the trigeminal nerve, which provides signaling pathways for periodontal and dental pain. The study has broad implications for trigeminal nerve regeneration and may lead to new treatments for various neuropathic and infl...
Researchers at OHSU School of Dentistry discovered a molecule, BDNF, that plays a critical role in the development and regulation of blood pressure. The finding may contribute to the prevention of Sudden Infant Death Syndrome (SIDS) and high blood pressure.
Researchers at USC School of Dentistry found a link between short-term use of oral bisphosphonates and increased risk of jaw necrosis. Nine patients out of 208 who took Fosamax were diagnosed with osteonecrosis of the jaw, contradicting previous claims that oral usage posed negligible risk.
The UCSF School of Dentistry has received a seven-year grant to launch programs preventing early childhood tooth decay. The initiative aims to reduce oral health disparities among vulnerable populations, particularly children in low-income families and minority groups.
Researchers found that older adults remember fewer negative events than younger counterparts due to differences in brain activity. The study suggests that seniors' brains use thinking rather than feeling processes to store emotional memories, which may improve understanding of mental health issues like depression and anxiety.
The University of Western Ontario has received $45.5 million in funding from the Canada Foundation for Innovation to develop new methods for growing stronger lab-grown bones and tissue. This will help address conditions such as arthritis, osteoporosis, and traumatic injuries, where current lab-grown materials lack sufficient strength.
The Robert W. Woodruff Foundation has pledged $3 million to support the construction of a new Medical College of Georgia School of Dentistry building. The gift will help alleviate the shortage of dentists in Georgia, with the school increasing its class size from 63 to 100 and residency positions from 44 to 72.
A Canadian scientist has made a significant breakthrough in treating intellectual disabilities by manipulating the genes of fruit flies. The research found that disrupting a specific gene called FMR1 leads to long-term memory loss, and that a class of drugs can help restore memories.
Vasovagal syncope is a common emergency situation in dental offices, characterized by loss of consciousness and muscle tone. Patients experiencing symptoms such as dizziness, lightheadedness, or pain may have an underlying cause that can lead to a life-threatening situation.
A study published in the Academy of General Dentistry reveals that stopping antiplatelet medications before dental procedures increases the risk of permanent disability or death. Dentists can help patients by discussing treatment risks and benefits with their physicians.
A study published in the Academy of General Dentistry journal found that brewed tea has a lower erosive effect on teeth compared to soft drinks and acidic juices. The study suggests that drinking brewed tea can help prevent tooth erosion, which can wear away the enamel and lead to irreversible damage.
Researchers found that teens engaging in risky behaviors like sex, smoking, and drinking are more likely to use crystal meth. In high-risk youth, family history of alcohol abuse, psychiatric treatment, and juvenile detention were associated with methamphetamine use.
Researchers at the University of Alberta have discovered how copy number variations contribute to pediatric glaucoma, a disease that can lead to blindness. The study's findings may help improve detection and treatment of childhood glaucoma, paving the way for earlier intervention and better outcomes.
Researchers found that Sharpie tips do not spread infection due to alcohol-based ink. In contrast, sterile markers with non-alcohol base ink were contaminated after 24 hours. The study suggests that reusable Sharpies can be used safely with proper cleaning and disinfection.
Researchers have identified five biomarkers in saliva that can confirm the presence of oral squamous cell carcinoma with 93% accuracy. The study, led by David T. Wong and Shen Hu, demonstrates a new approach for cancer biomarker discovery using saliva proteomics.
The Journal of Dental Biomechanics will cover tissue and material biomechanics, with a focus on hard and soft tissue analysis. The journal aims to provide a platform for researchers to share vital research and developments in dental biomechanics.
The International Association for Dental Research and American Association for Dental Research have partnered with SAGE to publish the Journal of Dental Research beginning in 2009. The journal will expand its reach through SAGE's marketing capabilities and consortia deals.
Researchers at USC School of Dentistry have discovered a new pathway that contributes to palate formation, bypassing the TGF-ß signaling molecule. This finding has implications for understanding cleft palate, tooth development, and diseases like cancer.
Nearly 20 million teeth are extracted annually, affecting patients' psychological well-being. Dr. Kiyak's course discusses ways to cope with tooth loss, including reviewing replacement options and testimonials from others who have undergone similar procedures. A great smile can boost self-esteem, confidence, and overall health.
A new study led by NYU Dentistry shows that weak HIV viruses can replicate and contribute to AIDS development through cooperative interaction with stronger viruses. This mechanism enables some viruses to reproduce faster and evade immune responses.
USC School of Dentistry researchers found that aspirin can inhibit bone resorption and promote osteoblast formation in mice with osteoporosis. The study's findings suggest that aspirin may be a potential alternative to current treatments for osteoporosis, which affect both men and women.
Dr. Childers' research on mucosal immune responses and dental caries vaccine development has contributed to a better understanding of oral health. He currently supervises projects funded by NIDCR, investigating host/parasite relationships in dental caries high-caries-risk populations.
Dr. Kathryn Atchison is being recognized for her outstanding achievements in dental public health and behavioral sciences, with over 70 peer-reviewed articles and a well-funded research program. She serves as Vice- Provost of Intellectual Property & Industrial Relations at UCLA and has held various leadership positions in the Ameri...
Dr. Adrian Lussi is recognized as a pioneer in dental erosion and caries research, with over 160 publications and executive positions. He received the Research in Dental Caries Award for innovative achievements in caries diagnosis.
Dr. Neal Garrett has been recognized for his research focus on restoring oral function and quality of life following tooth loss or other oral impairment in the elderly. He established the functional efficacy of various denture parameters and types utilizing dental implants, improving mastication and patient perceptions.
Researchers found that older adults' brains show increased activity in regions involved in emotion control, allowing them to regulate emotions better than younger counterparts. This 'positivity bias' helps seniors cope with emotionally challenging situations.
The National Institute of Dental and Craniofacial Research (NIDCR) is positioning the dental research community for future success through interdisciplinarity, collaboration, and innovation. The NIDCR is investing in practice-based research networks to move dentistry towards evidence-based practices.
Researchers at USC School of Dentistry have found a connection between bisphosphonate drugs and jaw infections, with biofilms playing a key role in the deterioration of jaw tissue. The study aims to develop effective treatments or prevention methods for osteonecrosis of the jaw.
Researchers at the University of Michigan discovered a link between specific antibodies and oral health, finding that healthy individuals have higher antibody levels to a key protein in periodontal disease. This discovery could lead to improved treatment responses and prevention strategies.
A study by Johns Hopkins Bloomberg School of Public Health found no statistically significant increase in calls with periods of increased alert among New Jersey law enforcement officers. Researchers analyzed call data from a crisis hotline and did not detect a pattern of increased calls corresponding to an elevation in the alert level.
Dr. Richard Stein has been awarded the Barbara Turnbull Award for Spinal Cord Research, a $50,000 prize, for his work on direct, microelectrical spinal cord stimulation. His innovative device aims to record sensory feedback from muscles and nerves in legs and hips to help paralyzed individuals walk.
Overweight children ages 6-18 show a decreased risk of caries compared to their normal weight peers. The study suggests that diet and lifestyle factors may play a role in the unexpected finding, highlighting the need for further research to better understand the relationship between obesity and oral health.
Researchers aim to create genetic profile of Streptoccocus mutans bacterium to predict disease in children from diverse backgrounds. The study's findings will propel the development of a diagnostic test to prevent devastating consequences of early childhood caries.
Researchers at the University of Michigan have discovered a method for controlling the growth rate of replacement tissue and forming new blood vessels. This breakthrough could be used in various medical procedures, such as bone grafts and dental treatments, to help patients with wound healing problems.
Dental amalgam's use is being restricted due to mercury concerns, but scientific evidence suggests a link between the two is unclear. The move may remove a viable treatment option for dentists and patients worldwide.
The LSUHSC School of Dentistry is being honored for its innovative efforts in rebuilding dental education in Louisiana following Hurricane Katrina. The institution has been recognized for its pioneering work in restoring a functional dental school, despite the devastating flood that rendered the campus unusable.
Researchers discover polyphenols in winemaking waste inhibit the ability of bacteria to cause cavities and form biofilms, potentially leading to new treatments for oral diseases. The findings also suggest the compounds may hold clues for lessening the ability of bacteria to cause life-threatening infections.
According to a study published in the General Dentistry journal, mouthguards can harbor large numbers of bacteria, yeasts, and molds. This can lead to life-threatening infectious/inflammatory diseases. Proper mouthguard maintenance, including regular cleaning and storage, is crucial to prevent disease transmission.
The Queensland Government's decision will ensure 80% of residents drink fluoridated water within two years and over 90% by 2012. Fluoride introduction is expected to reduce dental decay by up to 65% compared to non-fluoridated areas.
A recent study by Indiana University researchers found that fluoridated tap water reduces dental fillings and costs for all age groups, with older adults benefiting the most due to limited access to dental insurance. The study breaks new ground on adult dentistry, highlighting the importance of community water fluoridation for people o...
Research by The Peninsula College of Medicine and Dentistry found that maintaining physical activity in middle age leads to better basic physical abilities as we age. Physical activity is associated with fewer than 13% of people developing physical disability. Weight is not a deciding factor in this benefit.
Researchers discovered that different ethnic groups living in California manifest the disease very differently, with African Americans and Caucasians developing tongue cancer at higher rates. Cultural habits such as cigarette smoking and areca nut chewing contribute to the prevalence of oral cancer in certain groups.
The University of California - Los Angeles School of Dentistry has received a $1,876,920 NIH grant to develop an innovative tool for rapid and reliable assessments of the stress response to trauma as evidenced in saliva. This technology aims to unite healthcare providers in delivering comprehensive care to patients with facial trauma.