A study found that 78% of breast cancer patients had at least one other cause of bone loss besides cancer drugs. Vitamin D deficiency was the most common factor, affecting 38% of breast cancer patients compared to 51% of non-cancer patients.
A new review article in Circulation highlights the link between vitamin D deficiency and heart disease, with rates of severe disease or death potentially 30-50% higher among sun-deprived individuals. Treatment options such as vitamin D supplements may help decrease the risk of cardiovascular disorders.
Retired NFL players had a lower prevalence of diabetes and hypertension compared to control groups, but higher rates of elevated cholesterol and impaired fasting glucose. Staying physically active may help protect against these health risks in former athletes.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that dose-dependent growth hormone treatment increased final height in children with short stature who are not GH deficient. Children from parents of normal height responded better to treatment than those from short parents.
A study published in the New England Journal of Medicine found that testosterone administered by a skin patch improves sexual well-being in post-menopausal women. The research involved over 800 participants from across the globe and suggests testosterone as a potential treatment for low libido in this demographic.
A study of over 300 diabetics and their caregivers will measure the impact of insulin pump technology on quality of life, attitudes towards treatment, and lifestyle changes. The research aims to provide insights into the clinical implications and potential coverage by Medicare and health insurance providers.
Researchers found that fetuses of obese mother rats developed obesity in adulthood due to altered energy homeostasis and hormone levels. The study suggests that women maintaining optimal conditions during pregnancy may be crucial in preventing adult-onset obesity.
Researchers at Medical College of Georgia identified a new gene, chromodomain helicase DNA binding protein 7 (CHD7), responsible for some puberty disorders, including idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome. The study found that CHD7 mutations account for about 6% of IHH and Kallmann syndrome cases.
Research at University of New South Wales finds a link between maternal obesity and increased body fat in offspring. Pups from obese mother rats were nearly twice as heavy as those born to lean mothers with regular milk consumption.
Researchers discovered that injecting human recombinant interleukin-6 improved insulin sensitivity and glucose absorption, increasing fat metabolism genes. A preliminary study suggests this molecule could help prevent diabetes and obesity in humans in the medium term.
Researchers have identified two novel gene locations associated with an increased risk of developing type 1 diabetes. The study, published in Diabetes, provides a promising lead for the development of more accurate diagnostic tests and potential preventive therapies.
Boston Medical Center has received a $5.8 million grant to develop drugs targeting muscle proteins for older adults, improving mobility and preventing age-related ailments. The grant will support interdisciplinary research collaborations to address osteoporosis, hip fractures, and type one diabetes.
A study published in Archives of Diseases in Childhood found that only 42% of boys and 11% of girls met the recommended daily exercise level, suggesting a need for revised guidelines. Exercise improved metabolic health, but diet changes were deemed more effective at improving overall health and weight.
Researchers at the University of Illinois College of Medicine discovered a novel enzyme linked to anencephaly, a rare fatal birth defect. The study suggests that a genetic test may be developed to diagnose the condition early in pregnancy.
A recent survey found that most infertility patients support using leftover embryos for stem cell research, with 73% in favor. However, there is a growing demand from patients who want to sell their extra embryos to others, with 56% approving of the practice.
Researchers found significant declines in hip bone mineral density after gastric bypass surgery, associated with the extent of weight loss. Calcium and vitamin D deficiencies may be due to alterations in the gastrointestinal tract during these procedures.
A study by the Endocrine Society suggests prenatal testosterone excess may contribute to low sperm counts and reduced fertility in males. Researchers found that exposure to high levels of testosterone during fetal development can negatively impact male reproductive health.
Researchers at UNC School of Medicine have transformed human skin cells into insulin-producing cells using pluripotent stem cell technology. This breakthrough may lead to new treatments or even a cure for the millions of people affected by diabetes.
A large study has found a significant increase in fracture rates among HIV-infected patients compared to non-infected controls. The study, published in the Journal of Clinical Endocrinology and Metabolism, reveals that nearly 3% of HIV patients experienced fractures, with risks increasing with age.
The Endocrine Society has released a new clinical practice guideline for the detection, diagnosis, and treatment of primary aldosteronism. The guidelines recommend using the aldosterone-to-renin ratio to diagnose PA in higher-risk patients.
A new study published in the Journal of Clinical Endocrinology & Metabolism found that HIV-infected patients have a higher prevalence of fractures compared to non-HIV infected patients. The study analyzed data from over 8,500 HIV-infected patients and more than 2 million non-HIV infected patients, revealing a significant increase in fr...
A recent study published in the journal Diabetes found that fat tissue in obese patients has impaired cellular function, leading to increased risk of insulin resistance and related conditions. The researchers discovered significant differences in the cellular structure and function of fat cells between lean and obese individuals.
A study published in Diabetes Care found that young men with type-2 diabetes have significantly lower levels of testosterone, which can impact fertility, muscle development, and increase the risk of heart disease. The study also highlights the potential clinical implications of low testosterone in these individuals.
A study published in Nature Neuroscience identifies GABA as a key player in regulating energy balance, leading to leaner mice with increased energy expenditure and resistance to diet-induced obesity. The discovery suggests that targeting GABA release may be an effective strategy for tackling obesity and metabolic disease.
Researchers investigated estrogen's action in the brain, finding that it protects neurons and enables learning and memory throughout life. Estrogen receptors are present in both men and women, and a protein called PELP-1 enables rapid hormone action.
A commonly used diabetes monitoring test could be repurposed to screen for and diagnose diabetes, identifying millions of people with undiagnosed disease. The hemoglobin A1c test measures long-term glucose control, offering advantages over current testing methods that require fasting or are affected by recent meals and diet.
A new study found that those who drink excessively are at increased risk for metabolic syndrome, a condition associated with cardiovascular disease. The study analyzed data from over 1,500 participants and found that most people in the US drink in ways that may increase their risk of metabolic syndrome.
A new study found that a protein produced by fat cells may increase the risk of heart attack in older adults. Adiponectin levels were associated with a higher risk of heart disease events, particularly among those with high levels.
A new ovarian stimulation technique allows women with cancer to collect eggs for freezing during the luteal phase, reducing wait time before treatment. The technique has shown promising results in triggering ovulation and collecting mature eggs within two weeks.
Researchers discovered that turmeric-treated mice were less susceptible to developing Type 2 diabetes and showed reduced inflammation in fat tissue and liver. Curcumin's anti-inflammatory properties may lessen insulin resistance and prevent the disease.
A Finnish study of identical twins found that physical inactivity and acquired obesity impair the expression of genes involved in energy production, contributing to insulin resistance. The study suggests that lifestyle factors play a significant role in developing diabetes and heart disease.
Researchers found that increasing pro-resolution signals can cool down inflammation and slow down atherosclerosis. However, clamping down on these signals would fan the fire of inflammation and speed up its progression.
Older adults experience increased bone loss, but antiresorptive medications can attenuate this process. Researchers found that even in women aged 50-54, bone loss was only 1.3% per year.
Researchers found that resveratrol inhibits the growth of pre-fat cells and prevents them from converting into mature fat cells. Resveratrol also reduces production of cytokines linked to obesity-related disorders, such as diabetes and clogged coronary arteries.
A new study by The Endocrine Society found that moderate fitness levels lower the risk of death in diabetic men, reducing mortality by 40-50% over seven years. Fitness levels were categorized as low, moderate, and high based on peak metabolic rate achieved during exercise.
A new study by The Endocrine Society found that overweight men are not more likely to be infertile, contradicting previous research on obese women. Greater body weight was linked to lower testosterone levels in some participants, but impaired sperm production remains the primary cause of infertility in men.
LA BioMed investigator Dr. Ronald S. Swerdloff is recognized for his 39 years of teaching and training over 130 endocrine fellows. He has made significant contributions to the field of reproductive endocrinology, inspiring a legacy of outstanding trainees.
A unique drug combination, Lisofylline and Islet Neogenesis Associated Protein peptide, has shown promising results in reversing Type 1 diabetes in diabetic mice. The study found that the combination led to a remission rate of 70% in mice with high blood glucose levels.
Anne L. Peters, MD, CDE, received the American Diabetes Association's Outstanding Physician Clinician Award for her dedication to improving diabetes care, particularly in underserved populations. She has made significant contributions to the field through her research and clinical work.
Researchers at Rutgers University found that beta-endorphin peptide-producing neurons in the brain regulate stress response and immune function, controlling tumor growth. The study shows promise for therapeutic treatments to bolster the immune system.
Research shows that ewes fed a diet enriched with polyunsaturated fats have a significantly higher chance of giving birth to male offspring. This finding suggests that dietary composition around conception can influence sex ratio in farm species.
Researchers use zebrafish to track GnRH neurons' migration, a critical step in pubertal development. The study aims to understand molecular mechanisms behind delayed puberty and its causes, such as Kallmann syndrome.
Researchers found a previously unknown cooperation between pancreatic beta cells and alpha cells, crucial for glucose balance. The discovery may lead to better blood sugar regulation in diabetes patients by targeting the glucagon/glutamate pathway.
Researchers found that children can safely take ten-times the current recommended daily allowance of vitamin D, which may have long-term health benefits. Vitamin D is essential for bone growth and development in children, and supplementation with high doses (2,000 IUs) has been well-tolerated and safe.
A new study found that elderly men with higher IGF-1 bioactivity have a significantly lower mortality rate compared to those with low bioactivity. The researchers used a new method to measure IGF-1 function, which revealed the association between high circulating IGF-1 bioactivity and extended survival.
Experts recommend revising current criteria for diagnosing diabetes, suggesting the use of hemoglobin A1c (HbA1c) as an alternative to fasting plasma glucose or oral glucose tolerance tests. This change may help identify more people with undiagnosed diabetes, reducing avoidable morbidity and mortality.
A pilot study will be conducted in Vinh City, Vietnam, to screen people at high-risk for pre-diabetes and diabetes. The screenings will be coupled with community awareness and healthy living programs to promote a lifestyle modification program over three months.
A new Translational Research Center for PCOS will be established at VCU, focusing on genetics and pharmacogenomics to identify risk factors and optimal treatment. The center aims to bring research discoveries from the laboratory bench quickly to clinical care, improving outcomes for women with PCOS.
The IDF BRIDGES translational research grant program will fund a pilot study in the Philippines that aims to improve diabetes care in rural communities using local health workers. The program, called Diabetes Self-Management Program (DSME), will provide culturally-appropriate education and self-care practices for Filipinos with diabetes.
Treatment advances for fibroids and endometriosis aim to preserve reproductive potential while treating these conditions. Novel conservative approaches, including medical treatments and non-invasive procedures, are now available, offering women more choices during menopause.
Researchers found that administration of triflusal increased insulin secretion significantly in relation to dose size, but did not improve insulin sensitivity. The study's findings suggest salicylates may have a therapeutic benefit in the fight against type 2 diabetes in obese individuals.
A new study published in the Journal of Clinical Endocrinology & Metabolism reveals that anti-Müllerian hormone (AMH) levels can predict a woman's reproductive age and onset of menopause. AMH levels reflect the number of small follicles present in a woman's ovaries, enabling monthly ovulations.
Researchers at UC San Diego School of Medicine found that low levels of adiponectin, a hormone produced by fat cells, are linked to elevated albumin protein in the urine and increased inflammation in the kidney. The study suggests that supplementing with adiponectin or other therapies may help protect kidney function in obese patients.
Researchers followed Minneapolis school children from ages 11 to 19 to track the emergence of cardiovascular risk factors. By age 19, boys were at greater cardiovascular risk despite gaining muscle mass and losing fat during puberty.
A study by Children's Hospital of Philadelphia found that in the US and Asia, boys are twice as likely to receive growth hormone treatment for short stature compared to girls. The gender disparity is smaller in Europe and Australia, suggesting cultural biases towards male height in some countries.
Researchers found that continuous oral contraceptives significantly improved pain and behavioral changes in women compared to standard 28-day birth control pills. The study also showed a significant decrease in moderate to heavy bleeding days among women who received the continuous birth control regimen.
Researchers at USC have found that fasting for two days protects healthy cells from chemotherapy, while leaving cancer cells vulnerable. This discovery holds promise for developing more selective and less toxic chemotherapy treatments.
Research at Yale University reveals a link between grhelin, the hunger hormone, and decreased fertility. Grhelin's impact on reproductive health is seen in mice bred with low ghrelin levels, producing smaller litter sizes and altered uterine development.
Researchers at Yale University have successfully created new neurons using uterine stem cells, which increased dopamine levels and partially corrected Parkinson's disease symptoms in mice. This breakthrough has significant implications for the development of a potential human treatment.
Researchers at Yale University found that exposure to DES alters HOXA10 gene expression, leading to uterine cancer and fertility problems in female offspring. Long-term effects of similar substances like BPA on reproductive health remain a concern.