Research at the University of Chicago found that children with brain injuries have difficulty developing story-telling skills. The study, published in Developmental Science, compared the language abilities of children with brain injuries to those with typical development. While vocabulary and sentence comprehension were similar, the ch...
A recent study published in Neurology found that individuals with larger heads who have Alzheimer's disease tend to exhibit better memory and cognitive skills. The research suggests that brain reserve, or the individual capacity to withstand changes in the brain, plays a crucial role in protecting against Alzheimer's symptoms.
A study found that the human brain regions growing during infancy and childhood are similar to those with the most changes when comparing humans to apes and monkeys. This research helps assess adverse effects of premature birth on brain development, including increased risks of learning disabilities and cognitive impairments.
A recent study by UCL scientists found that the brain is intrinsically unreliable due to high levels of noise. The researchers proposed a rate code strategy as a possible solution to this problem.
A study published in Neurology found that brain injuries disrupt sleep regulation, resulting in lower melatonin levels and decreased sleep efficiency. The study suggests that taking supplemental melatonin may improve sleep in people with brain injuries.
Researchers found significant patterns in discarded brain wave data, revealing connections between low-frequency and high-frequency brain waves. These connections suggest important aspects of brain architecture and function, potentially shedding light on the brain's organizational structure.
Researchers found that PDE5 inhibitors increase blood-brain barrier permeability to Herceptin, boosting effectiveness against lung and breast cancer brain metastases. The combination of vardenafil plus Herceptin improved survival by 20% in mouse models.
A new study published in Neurology shows that people with a common heart defect called bicuspid aortic valve (BAV) are more likely to develop brain aneurysms. The research found that 9.8% of individuals with BAV had brain aneurysms, compared to 1.1% of those without the condition.
A new brain implant made from silk has been developed to monitor and control seizures, as well as transmit signals past damaged spinal cord areas. The ultrathin flexible implants can record brain activity more faithfully than thicker devices, with potential applications in epilepsy, spinal cord injuries, and other neurological disorders.
Researchers mapped over 4 billion neuronal interactions to reveal synchronized brain areas during working memory tasks. The study shows that rhythmic activity between brain regions is linked to both memory maintenance and content.
Researchers have discovered that targeting the blood-brain barrier can slow the accumulation of a protein associated with Alzheimer's disease. The study shows that activating a certain receptor in the brain can increase the expression of a blood-brain barrier protein that transports beta-amyloid out of the brain.
Researchers link differences in brain network harm to impairment in stroke patients, offering a new predictive tool for clinicians. This approach, known as resting-state functional connectivity, may help determine treatment and assess its effects.
Researchers at the University of Washington studied brain signals in eight patients awaiting epilepsy surgery, finding that imagined movements can strengthen brain activity. After less than 10 minutes of practice, brain signals from imagined movement became significantly stronger than when actually performing the physical motion.
A new study has uncovered a key cellular mechanism that alters brain cell function in Huntington's disease and identified a possible treatment for the disease. Researchers found that excessive NMDA receptors outside synapses lead to reduced brain cell survival signals and disruption in brain function.
Researchers reconstruct primate brain evolution to clarify the Hobbit's brain size, suggesting a strong selective advantage for increased brainpower. The study supports the hypothesis that the Hobbit's small brain was adapted to local ecological conditions on Flores.
Alexander Ksendzovsky, a third-year medical student, has been awarded the Lucien Rubenstein Award for his groundbreaking research on a potential vaccine to fight malignant brain tumors. The American Brain Tumor Association recognized his outstanding work as part of their annual Research Award Program.
Neuroscientists and computer scientists identified how the brain arranges noun representations, using a neural Rosetta Stone. The three basic features of the brain's dictionary concern physical interaction, eating, and shelter or enclosure. This discovery has implications for treating psychiatric and neurological illnesses.
Researchers have identified two molecules, K and D, that stabilize brain circuitry development and enhance visual learning in mice. Removing these molecules can improve performance in visual tasks.
The first national and evidence-based guidelines for brain metastases have been released in the US, providing a framework for treating patients with brain tumors. The guidelines cover various therapeutic options, evidence-based decision-making, and demographic factors that influence clinical decisions.
Researchers at Mayo Clinic found that inflammation in the brain helps clear amyloid deposits, contradicting long-standing scientific belief. The study suggests that manipulating brain inflammation could be a potential therapeutic approach to treat Alzheimer's disease.
Researchers found that whole-brain radiotherapy did not extend lives or improve independence in patients with limited brain metastases and stable cancer. However, it slowed cancer progression by five weeks and reduced the risk of brain-related deaths.
Researchers at the University of Iowa discovered a way to deliver therapeutic molecules directly into brain cells using the blood-brain barrier. They found that unique alterations in the blood vessels surrounding brain cells can target specific diseases, allowing for non-invasive treatment of lysosomal storage diseases.
A new study has found that nearly three percent of healthy people have an abnormality on a brain MRI scan, raising concerns about the benefits of commercial brain screening. The researchers argue that there is limited medical evidence to support treatment for incidental abnormalities, potentially creating anxiety among patients.
A Clemson University bioengineer has developed an injectable biomaterial gel that promotes the growth of neural stem cells at the site of a traumatic brain injury, structurally repairing damaged brain tissue. The procedure shows promise for treating head injuries caused by car accidents, falls, and gunshot wounds.
Research found that brain processes living and non-living objects in different areas, regardless of visual experience. The brain categorizes objects based on their functional importance, such as edibility or spatial awareness.
Researchers at Tel Aviv University use Diffusion Imaging MRI to track memory changes and explore early detection of Alzheimer's disease. The study reveals that brain microstructure can change in mere hours, allowing for a quantifiable measure of individual brain plasticity.
The study uncovered the unlikely genetic suspect, FOXC1, which critically contributes to Dandy-Walker malformation, a brain defect causing mental retardation and motor delays. The discovery provides new mechanisms and potentially improves treatment for the disorder, offering insights into embryonic brain development.
Researchers at the University of Washington developed nanoparticles that cross the blood-brain barrier, illuminating brain tumors and improving MRI and optical imaging. This breakthrough could lead to more precise surgery and earlier cancer detection.
Researchers have devised a chemical technique to discover brain function and provide clues for treating brain diseases. The technique allows neuroscientists to noninvasively activate entire populations of neurons in an animal brain, promoting understanding of brain function and disease treatment.
A team of researchers from Ben-Gurion University and UC Berkeley have identified a TGF Beta Blocker that prevents epilepsy in rats after brain damage. The blocker blocks hyper-excitability and gene expression changes that lead to epilepsy.
Researchers found distinct brain structure differences between queens and workers of eight New World social wasp species, linked to their respective social roles. Brain regions responded to specific challenges, such as vision and chemical communication, revealing the importance of environment in shaping brain architecture.
Researchers at UCLA's Brain Injury Research Center are re-examining the standard treatment for traumatic brain injury (TBI), suggesting that fueling the brain with glucose may not be the best approach. Instead, they propose using alternative compounds like pyruvate and beta-hydroxybutyrate to optimize recovery.
Researchers Finarelli and Flynn challenge the Social Brain Hypothesis, finding that increased brain size is not routinely associated with sociality in carnivores. They document at least six separate changes in brain sizes across different lineages of mammals.
A new study reveals that child brains are differently organized than adult brains, but still capable of performing complex cognitive tasks. Researchers found that young brains have localized networks based on physical proximity, which transition to long-distance networks centered on functionality as children mature.
Chronic smoking impairs brain blood flow recovery after long-term heavy drinking, according to a new study. Brain perfusion in frontal and parietal cortices improved with abstinence, but smokers showed significantly less recovery, particularly in the frontal lobes.
Research at Memorial Sloan Kettering Cancer Center identifies three genes mediating breast cancer's spread to the brain. COX2 and HB-EGF prime cells for entrance, while ST6GALNAC5 enables passage through the blood-brain barrier.
The study found that children with autism rely on a region of the brain for conscious movement, while typically developing peers use a region for automating motor tasks. Decreased connectivity between brain regions involved in motor planning and execution was also observed.
Adolescents and young adults who are heavy users of marijuana are more likely to have disrupted brain development, according to a new study. The researchers found abnormalities in areas of the brain involved in memory, attention, decision-making, language, and executive functioning skills.
Scientists found that exposure to blast overpressure from certain weapons, such as anti-tank guns and automatic rifles, causes mild brain injuries in pigs and rats. The study's results suggest that low frequencies are more effectively transmitted to the brain than high frequencies, leading to small haemorrhages and brain edema.
Researchers at the University of Pennsylvania School of Veterinary Medicine have imaged the body's immune response to a parasitic infection in the brain for the first time. The findings provide unexpected insights into how immune cells are regulated in the brain and have implications for treating inflammatory conditions.
The study proposes a theoretical model of the brain's coordination dynamics and applies a novel 4D colorimetric method to human neurophysiological data. It reveals that both integration and segregation occur in the brain, essential for its normal function.
Researchers used innovative brain-scan technology developed at UCLA to help diagnose brain aging, often before symptoms appear. The study combined PET scans with patient-specific information on Alzheimer's risk and found that older age correlated with higher concentrations of abnormal protein deposits in the brain.
The study aims to separate dysfunctional brain activity from 'noise' using spatial statistical modeling, a new technique that uses neighboring locations to strengthen weak signals. The research could help identify specific areas of the brain affected by the syndrome in Persian Gulf War veterans.
Researchers at Washington University in St. Louis have developed a new brain-computer interface (BCI) technology that can detect and decode brain signals associated with hand and arm movements on the same side of the body. This breakthrough may enable patients with partial paralysis to regain mobility in their limbs.
Researchers have identified Wnt/b-catenin signaling as a key pathway regulating brain development and maintaining the integrity of the blood-brain barrier. The study suggests that tweaking this signaling pathway could potentially mend damaged blood-brain barriers in patients with stroke or other conditions.
Researchers have developed a novel drug delivery system that can cross the blood-brain barrier to reach and kill cancer cells in the brain. The technology has shown promise in preclinical trials, with increased survival rates and reduced tumor growth in mice and rats.
Researchers found that the brain utilizes lactate as fuel during intense physical activity, outpacing glucose usage. This discovery sheds light on the brain's energy needs and has potential implications for treatment and athletic performance.
Researchers have discovered a persistent brain signal that never switches off, suggesting its role in supporting cognitive functions and maintaining the brain's structure. This low-frequency signal is thought to be more fundamental than previously identified gamma frequency activity.
A family history of brain tumors is linked to a higher risk of developing the same type of tumor. Researchers found that people with immediate relatives who suffered from glioblastomas or astrocytomas were nearly four and twice as likely to contract the same kind of brain cancer, respectively.
The study found that placental insufficiency leads to smaller brain volume in preterm infants, and degree of prematurity is the single most significant risk factor for brain injury. The research also suggests a link between genetic regulation of an inflammatory transmitter and brain growth.
Scientists at Boston Children's Hospital have identified the Otx2 protein as a key factor in triggering brain plasticity, allowing the brain to rewire and adapt. This discovery has implications for understanding developmental disorders like autism and potential treatments for improving learning and cognitive function.
Researchers found that PDE5 inhibitors like Viagra and Levitra can open the blood-brain tumor barrier, allowing cancer-fighting drugs to reach malignant brain tumors. This breakthrough may improve drug delivery to brain tumors in patients.
A new study from Baycrest Centre for Geriatric Care overturns the notion that brain noise decreases with maturity. Brain maturation leads to more stable and accurate behavior in memory tasks, but also correlates with increased brain signal variability.
Scientists at Schepens Eye Research Institute have identified specific molecules that awaken dormant brain stem cells, which can transform into neurons and repair damaged brain tissue. The findings suggest that tapping the brain's regenerative potential may be a promising approach for treating neurodegenerative diseases.
A study found that childhood lead exposure is associated with decreased brain volume in adulthood, particularly in men. The greatest brain volume loss was seen in participants with the highest lead exposure in childhood. This suggests that early lead exposure may disrupt brain development and result in persistent alterations.
A new neuroimaging study maps functional brain areas to improve cognitive skills before, during, and after brain tumour surgery. The study uses fMRI to localize important areas and preserve motor, sensory, and cognitive abilities.
Researchers at Harvard have developed gene probe eye drops that enable non-invasive monitoring of brain activity in living organisms. The technology uses MRI to detect tissue repair and has potential applications in treating neurological diseases, diagnosing conditions, and delivering therapeutic agents to the brain.
Inhalation of diesel exhaust induces stress response in brain activity, altering information processing. Researchers found that even short exposure can cause changes in brain waves, with effects lasting after subjects leave the room.
A study published in AIDS found that neural progenitor cells can form HIV reservoirs in the brain, similar to astrocytes. These cells have the potential to replicate the virus and transmit it outside the brain. Researchers hope to investigate how to protect these cells from the virus and develop new treatments.
Researchers find that adenosine, a sleep-inducing brain chemical, plays a central role in deep brain stimulation's success. The technique disrupts abnormal nerve signals and alleviates symptoms in patients with Parkinson's disease and other brain disorders.