A study published in the Journal of Clinical Investigation found a link between a brain protein called CREB and anxiety-related behaviors in rats. Lower levels of CREB were associated with high anxiety and increased alcohol consumption in genetically predisposed rats, suggesting that drinking may be used as a self-medication strategy.
A new study published in The Journal of Clinical Investigation found that decreased function of the CREB gene transcription factor is involved in anxiety and excessive alcohol drinking behavior. Decreased CREB function was shown to be important for maintaining high anxiety and excessive alcohol drinking. This genetic determinant create...
A large cohort study found a significant association between panic disorder and an increased risk of coronary heart disease. The study, which analyzed data from nearly 40,000 patients, suggests that cardiologists and internists should monitor patients with panic disorder to reduce the risk of cardiovascular disease.
Interpersonal and Social Rhythm Therapy (IPSRT) has been found to be an effective treatment for bipolar disorder, helping patients manage daily routines and relationships to prevent mania and depression. The study suggests that IPSRT is particularly beneficial for individuals with more regular social routines and better physical health.
A study by Gavan McNally and colleagues found that opiate users are more susceptible to stress-induced anxiety. The researchers tested rats with morphine or saline solution, then subjected them to restraint stress. The results showed that opiate-treated rats experienced greater anxiety responses, including reduced social interaction, a...
Co-occurring anxiety disorders, particularly social phobia and panic disorder, increase the risk of relapse to drinking. Screening for these conditions is essential in alcoholism treatment settings.
Men with severe anxiety/nervousness face nine-fold higher risk of attempted suicide compared to those without such issues. Long-term studies in Sweden reveal a significant correlation between reported anxiety and increased mortality rates from all causes.
A study by researchers at the University of Michigan Health System found that patients learned more facts from educational videos than from their doctors during a clinic visit. However, the video was less effective in reducing anxiety and stress levels compared to face-to-face interactions with their doctors.
Research shows that oxytocin increases maternal aggression and decreases anxiety during lactation. In a study on virgin rats, oxytocin was found to reduce anxiety and promote social dominance behavior. The hormone's role in regulating reproductive systems and behaviors is also being explored.
Researchers found that participants with a thicker ventromedial prefrontal cortex (vmPFC) were less anxious when viewing images associated with discomfort, suggesting a protective factor against anxiety disorders. The study's results may inform the development of exposure-based therapies for anxiety disorders.
New study finds bipolar disorder prevalence higher than previously thought, with a significant economic burden and high risk of suicide; Lithium treatment may help reduce these risks.
Research identifies genetic linkages associated with bipolar disorder, including a possible connection to autoimmune thyroiditis. The findings suggest that identifying these genetic markers could help develop more effective treatments or prevent the disorder in at-risk individuals.
A study based on US National Comorbidity Survey Replication data found that 26.2% of adults in the US had a mental disorder, with anxiety disorders being the most prevalent. Severity levels showed 22.3% as serious, 37.3% as moderate, and 40.4% as mild.
A study of young adults found a strong association between asthma and panic disorder, with active asthma predicting subsequent panic disorder. The 'electronic nose' technology also showed promise in detecting lung cancer by analyzing exhaled breath samples.
A study of NYC public school children found a high proportion had a probable mental disorder six months after the 9/11 attack. The severity of exposure was related to disorder rates, with family exposure being a stronger factor than direct exposure.
Researchers found a previously unknown safety circuit in the brain that contributes to feelings of security and well-being, contradicting previous theories that linked anxiety disorders only to fear. The discovery may lead to new treatments targeting sense of safety and security.
Research suggests that post-traumatic stress disorder (PTSD) is a significant concern among refugee populations in western countries. Studies indicate that approximately 1 in 10 adults experience PTSD, while others may struggle with major depression and generalized anxiety disorders. The findings highlight the need for increased attent...
A randomized controlled trial found that combining cognitive-behavioral therapy (CBT) with medication significantly improved treatment outcomes for patients with panic disorder. Patients receiving CBT and medication had higher remission rates and greater improvements in mental health functioning compared to those receiving usual care.
A study found that bipolar disorder is prevalent among patients in an urban primary care clinic, with 9.8% screening positive for the condition. Patients who screened positive reported worse health-related quality of life and social impairment compared to those who did not screen positive.
A study of 150 subjects found that listening to a relaxation tape prior to and during mammography did not decrease women's feelings of pain and anxiety. In fact, virtually none of the participants experienced pain or anxiety during the test, contradicting previous studies that attributed non-compliance to pain.
Researchers found that Whites perceive significantly more disorder than Blacks, Latinos, and Asians, even when living in the same neighborhood. The study suggests implicit bias in perceptions of disorder contributes to continued racial segregation in the US.
A 20-year study at Columbia University Medical Center found that depression risk increases with each subsequent generation. Children from families with a two-generation history of depression are at high risk for developing anxiety disorders and experiencing more impairment as they age.
Researchers used fMRI to capture the brain's unconscious emotional processing of fearful faces, revealing activity in the amygdala and cortex. The study found that anxious individuals showed more brain activity, indicating a biological basis for unconscious emotional vigilance.
A Yale University study found that children with increased preoperative anxiety are more likely to experience delirium and new maladaptive behavioral changes after surgery. Children who are younger, more emotional, and less social are at high risk of developing these issues.
Researchers have identified significant differences in brain chemistry between people with and without bipolar disorder using MR spectroscopy. The study's findings suggest that this imaging tool may help distinguish bipolar disorder from major depression, improving treatment outcomes.
Researchers found that extended-release carbamazepine capsules improved symptoms in patients with bipolar disorder, including those experiencing mania and mixed episodes. The treatment was generally well-tolerated, with few adverse events reported.
A recent study using data from 43,093 adults found that 24.9% were current cigarette smokers and 12.8% were nicotine dependent. Those who were nicotine-dependent consumed 57.5% of all cigarettes smoked in the US, highlighting the need for targeted smoking cessation efforts on individuals with nicotine dependence and psychiatric disorders.
A UCI study discovered a new brain protein, NPS, that regulates sleep and anxiety. The findings suggest that NPS can be a target for new drugs to treat sleep disorders and anxiety.
Neuropeptide S promotes arousal and anxiolytic-like effects, regulating sleep-wake cycles and anxiety. The discovery may help understand sleep disorders and pathological states of anxiety.
The NESARC study reveals high rates of comorbidity between substance use disorders and independent mood and anxiety disorders. Approximately 20% of persons with a current substance use disorder experience a mood or anxiety disorder within the same time period.
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) survey found that over 16 million Americans had a personality disorder, with avoidant, dependent, and paranoid disorders more prevalent among females. The study highlights the importance of addressing these conditions to prevent further impairment.
The study found that substance use disorders and independent mood and anxiety disorders are widespread in the US population, with significant associations between them. Approximately 20% of individuals with a current substance use disorder had at least one current independent mood disorder or anxiety disorder.
A study found that high maternal anxiety during a specific period in pregnancy (12-22 weeks) can program the fetus's brain, increasing susceptibility to childhood disorders. This effect was more pronounced than other factors such as smoking or low birthweight.
A Temple University study found that training nurses on end-of-life care can temporarily boost anxiety about death, but this effect wanes over time. The research suggests that repeated educational programs may be necessary to help nurses manage their anxiety in the long term.
The BOLDER trial found SEROQUEL significantly reduces anxiety symptoms in bipolar depression patients within the first week of treatment. It also improves depressive symptoms and is well-tolerated with a favorable side effect profile.
Researchers found that Puerto Rican children with parents reporting asthma were more likely to have depressive disorders. Children experiencing asthma attacks were also at higher risk for anxiety disorders, including separation anxiety.
Researchers at the University of Illinois Chicago discovered a gene, CREB, that regulates brain function during development and learning. Mice with only one copy of the CREB gene exhibited increased anxiety-like behaviors and consumed more alcohol than normal littermates.
A study found that lifetime exposure to adversity is associated with an increased risk of developing depressive or anxiety disorders in young adults. The researchers analyzed data from 1,803 interviews and found that the level of adversity was a significant predictor of these disorders.
A study found that immediate mammogram reading can decrease stress and anxiety in women, especially those receiving false-positive results. Women who received rapid evaluation of their mammograms reported less anxiety than those who had to wait several days for results.
The U-M study found lower rates of major depression, panic disorder, social phobia, and generalized anxiety disorder among African Americans, especially men. Afro-Caribbean women had higher rates of mental disorders compared to their counterparts, likely due to structural inequalities in economic and social resources.
A study found that individuals with panic disorder have reduced expression of the 5-HT1A receptor protein, which regulates serotonin synthesis and release. This reduction is associated with decreased function in brain areas critical for anxiety regulation.
A study found that adolescent rodents experience less anxiety and recover faster from a hangover than adult rodents. In contrast, adolescents tend to drink more in social situations due to the lack of aversive effects, which may lead to dependency.
A study found that individuals with high levels of social anxiety use alcohol more often to relieve social discomfort and avoid social situations without alcohol. They experience greater relief from anxiety in social situations, but not full relief, suggesting a self-medication strategy that may lead to increased risk of alcoholism.
A study by Children's Hospital of Philadelphia found that children with behavioral disorders, such as anxiety and depression, incur significant healthcare costs comparable to those with physical disorders. The study suggests that increased hospitalization expenditures are a major contributor to these costs.
A study by Northwestern University researchers found that nearly a third of jailed teenagers have co-occurring substance abuse disorders and ADHD or behavioral disorders. The authors suggest that mental health professionals must collaborate with the juvenile justice system to improve screening, diversion, and access to treatment.
Research on fear extinction suggests that cognitive enhancers like D-cycloserine can accelerate the learning process of fear extinction, leading to more rapid and lasting reductions in phobias. Virtual reality therapy combined with DCS resulted in significant improvements in patients' anxiety levels.
A study found that parents' attitudes towards social anxiety disorder treatment can significantly impact their children's benefits from therapy. Parents who had used medication or counseling in the past were more favorable towards these treatments, and those with a history of emotional problems preferred counseling.
A study published in Psychosomatic Medicine found that women have higher levels of anxiety after a heart attack compared to men. The researchers also discovered that both men and women under age 60 reported higher anxiety levels, while older individuals experienced lower anxiety due to their expectation of illness.
A new study measures the emotions of doctors-in-training, finding that anxiety, guilt, and compassion are prevalent feelings. The research highlights the importance of acknowledging and managing these complex emotions to improve medical education and patient care.
A new study suggests that psychological factors like anger and anxiety may boost heart risk in postmenopausal women. Hormone replacement therapy provides some artery protection for women with high levels of anger and Type A behavior, but not for those with anxiety or depression.
Postconflict psychiatric research reveals high prevalence of common mental disorders, particularly post-traumatic stress disorder and anxiety disorder. Exposure to violence is a potent risk factor for various disorders, with comorbidity analyses showing complex relationships between disorders.
Researchers found that children with behavioral disorders incur similar healthcare costs to those with physical disorders. Children with depression and anxiety had double the overall expenditures as those with disruptive disorders.
Researchers studied 65 families with bipolar disorder and found strong genetic 'linkage' to specific regions on chromosomes 13 and 22, suggesting common genes contributing to both bipolar disorder and schizophrenia. These overlap genes may explain why the same anti-psychotic medications are effective treatments for both diseases.
A study at the University of Illinois Chicago found that a protein in the brain, CREB, controls drinking behavior in laboratory animals. Low levels of active CREB or neuropeptide Y correlated with symptoms of anxiety and excessive alcohol consumption.
A recent study by Ohio State University researchers found that nearly three-quarters of hospitalized patients with anxiety received treatment, but symptoms were documented on less than half of their charts. The study highlights the need for systematic evaluation and objective measures to address anxiety management in healthcare.
Researchers discovered a correlation between a specific genetic variation in the COMT gene and higher levels of anxiety in women. Women with the COMT Met158/Met158 genotype tended to exhibit increased anxiety symptoms, as well as altered brain wave patterns associated with anxiety disorders.
A team of researchers has identified a gene, Pet-1, crucial for serotonin neuron development, which is associated with abnormal anxiety and aggression in mice. The discovery provides a valuable animal model for understanding the causes of mood disorders and developing new treatments.
A recent study found that nearly 60% of males and over two-thirds of females met diagnostic criteria for mental or substance use disorders, highlighting a significant concern for the high rates of depression and dysthymia among detained youth.
Researchers at the University of California - Irvine have discovered two new compounds, URB532 and URB597, that relieve anxiety by inhibiting the breakdown of natural neurotransmitters, similar to Prozac. These gentler biochemical approaches may lead to more effective and side-effect-free treatments for anxiety and depression.
A new study has found a significant link between generalized anxiety disorder and peptic ulcer disease, with individuals experiencing more anxiety symptoms being more likely to report ulcers. The study suggests that persistent, severe anxiety and infectious agents may both contribute to the development of peptic ulcers.