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1,000+ results for "Stem Cells"

Chemical turns stem cells into neurons say scientists at Scripps Research Institute

Researchers have identified small chemical molecules that can direct embryonic stem cells to become neurons, paving the way for potential treatments of neurodegenerative diseases like Parkinson's and Type 1 diabetes. The study provides important insights into the molecular mechanism controlling stem cell fate and may lead to new therap...

SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateJun 2, 2003

Scientists discover unique source of stem cells

Researchers have identified a new source of stem cells in human teeth, known as SHED (Stem cells from Human Exfoliated Deciduous Teeth), which can grow rapidly in culture and differentiate into specialized cells. This discovery may lead to breakthroughs in tooth repair, bone regeneration, and neural injury treatment.

SourceNIH/National Institute of Dental and Craniofacial Research·JournalProceedings of the National Academy of Sciences·DateApr 21, 2003

Bone marrow transplants may be improved due to the uncovering of a key mechanism

Researchers discovered that degradation of SDF-1 protein is crucial for stem cell mobilization in bone marrow transplants. G-CSF growth factor triggers this process by reducing SDF-1 levels, allowing stem cells to flow into the bloodstream. The findings may lead to improved collection of stem cells for clinical transplantations.

Transplanted stem cells restore function in stroke

Researchers at the University of Minnesota have successfully transplanted stem cells into laboratory animals with stroke, restoring brain function. The study demonstrates that bone marrow-derived stem cells can differentiate into neurons, astrocytes, and oligodendroglia, offering hope for future clinical trials.

SourceUniversity of Minnesota·JournalExperimental Neurology·DateMar 4, 2002

Blood stem cells carry targeted genes

Scientists have successfully genetically altered human blood stem cells to selectively activate genes in developing immune cells, providing a potential breakthrough for gene therapy. The research uses a lentivirus to transfer a fluorescent protein gene into stem cells, which then express the gene only in specific immune cells called an...

SourceJohns Hopkins Medicine·JournalBlood·DateJan 8, 2002

Oxygen is toxic to stem cells

A study by Michigan Medicine researchers found that high oxygen levels can be toxic to stem cells, converting muscle cells into fat cells. This discovery has important clinical implications for the treatment of obesity and diabetes, as it may be related to aging and oxidative stress conditions.

SourceMichigan Medicine - University of Michigan·JournalJournal of Cellular Physiology·DateNov 7, 2001

Study identifies new source of stem cells

Researchers at McGill University have isolated novel stem cells from the dermis of adult rodents that can differentiate into various cell types, including neurons and muscle cells. These multipotent stem cells, known as SKPs, hold promise for treating Parkinson's disease and other neural disorders.

SourceMcGill University·JournalNature Cell Biology·DateAug 13, 2001

Stem-cell research: Drawing the line

The use of embryonic stem cells is a contentious issue, with proponents arguing that they hold promise for medical breakthroughs. However, opponents claim that destroying an embryo is tantamount to infanticide. Scientists generally favor the use of embryonic stem cells due to their versatility.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJul 23, 2001

Enzyme-based method to isolate stem cells from umbilical cord blood shows promise

Researchers have developed a new method to identify and isolate stem cells from umbilical cord blood using an enzyme that changes a fluorescent tag. This technique could help investigate fundamental questions about stem cells and potentially improve success rates of stem cell transplants by eliminating unwanted mature blood cells.

SourceDuke University Medical Center·JournalProceedings of the National Academy of Sciences·DateAug 2, 1999