Researchers developed a novel exosome-based treatment to deliver VEGF antibodies and suppress inflammation in ocular diseases. The therapy, rEXS-cL-aV, showed potent therapeutic efficacy in murine and nonhuman primate models.
Researchers reconstructed full-frequency precipitation variability in the Asian Summer Monsoon using a 6,700-year tree-ring stable isotope chronology. The data suggests a long-term decreasing trend and several abrupt climate change events, including a drought regime from ~1,675-1,185 BCE.
A study on gymnosperm diversification reveals that gene duplications are linked to major pulses of phenotypic evolution. The researchers found that ecological opportunity and environmental heterogeneity drove a resurgence of gymnosperm diversification since the rise of angiosperms.
A research team has explained the cause of Jupiter's X-ray aurorae, a phenomenon puzzling scientists for decades. The study found that heavy ions with mega-electron volt energies produce the auroral flares, triggered by magnetic compression and electromagnetic waves in Jupiter's magnetosphere.
A global network of microbiomes reveals that only six 'relatives' (or seven 'steps') separate any two microbiomes on Earth, indicating a common origin. The study also sheds light on the interactions between microbes in different ecosystems and their responses to climate change.
The Large High Altitude Air Shower Observatory (LHAASO) has accurately measured the brightness of the Crab Nebula over a record-breaking energy range. The measurement confirms past findings and provides direct evidence for the acceleration of high-energy electrons in the nebula.
Researchers developed hybrid membrane nanovaccines that educate patients' immune systems to distinguish tumor components as 'non-self', preventing recurrence and metastasis. The vaccines induce robust innate and adaptive immune responses, offering a new opportunity for individualized cancer vaccines.
A joint research team led by Prof. FU Qiaomei has sequenced the ancient genomes of 31 individuals from southern East Asia, unveiling a missing piece of human prehistory. The study reveals three genetically distinct ancestries in southern East Asia and Southeast Asia: Fujian ancestry, Hòabìnhian ancestry, and Guangxi ancestry.
Researchers from ITP of Chinese Academy of Sciences use water meters to estimate annual total river runoff for 13 major rivers in the region. The study reveals significant regional variations in river runoff, with higher values found in Indian monsoon domain, and shows climate change impacts on snow and glacial melting.
A 120-million-year-old fossil of a tiny bird found in China shares structural and functional features with the massive Tyrannosaurus rex. The discovery sheds light on the evolution of birds from dinosaurian ancestors.
Researchers have developed a Ramanome Database to rapidly identify and characterize microalgae, which can convert carbon dioxide into valuable compounds. The database achieves 97% accuracy in identifying species and their metabolic functions, accelerating the mining of microalgal cell factories for carbon-neutral production.
A new species of Paraceratherium has been discovered in China, shedding light on the dispersal of giant rhinos across Asia. The study found that the giant rhino could disperse freely from the Mongolian Plateau to South Asia along the eastern coast of the Tethys Ocean and perhaps through Tibet.
Researchers have successfully driven nanoparticles to orbit below light diffraction limit, achieving high orbital rotation speeds of over 1000 r/s and subdiffraction radii of 70 nm. This new mechanism enables efficient spin angular momentum conversion to orbital angular momentum.
Research found reduced microbial stability and increased soil organic carbon loss in degraded alpine permafrost on the Qinghai-Tibet Plateau. This degradation can lead to a positive carbon-climate feedback, exacerbating global warming.
Researchers have found that summer rainfall on the Tibetan Plateau is highly predictable on multiyear timescales using large ensemble predictions. The study reveals a substantial underestimation of the predictable signal in state-of-the-art decadal prediction models.
A recent experiment by Prof. YAN Xingbin's group reveals that an external magnetic field can induce capacitance change in aqueous acidic and alkaline electrolytes but not in neutral electrolytes, providing insight into ion transport behavior.
A new study by Chinese Academy of Sciences researchers has revealed diverse magnetic field morphologies in Solar-type star-forming cores in the Taurus B213 region. The findings contradict expectations based on theory that magnetic fields regulate star formation.
The researchers reported a reference sequence for the supernumerary B chromosome in maize, with key properties such as its origin and molecular mechanism remaining unclear. The study found that the current gene content is a result of continuous transfer from the A chromosomal complement over an extended evolutionary period.
Researchers analyzed ancient DNA from 25 humans, revealing that the population dynamics between 40,000-9.5 ka were influenced by Ice Age climatic fluctuations. The study provides evidence for an Asian-specific variant associated with anthropogenic traits.
Scientists have created a new instrument that can sort and sequence the genome of individual soil bacteria while identifying their functions. The RACS-Seq technique uses laser tweezers and gravity to analyze each bacterium one by one.
A new strategy using massive molecular dynamics simulations has been proposed to improve the energy density and power density of EDLCs with ILs. By introducing ionophobicity, the researchers found a significant enhancement in overall performance, particularly with an extremely ionophobic electrode.
Fossil seed-bearing structures from China's Early Cretaceous period show a recurved cupule with two seeds, suggesting a link to extinct non-angiosperm plants. The discovery supports an earlier idea about the origin of flowering plants' distinctive outer seed covering.
The Galactic Plane Pulsar Snapshot (GPPS) has discovered 201 pulsars using the Five-hundred-meter Aperture Spherical radio Telescope (FAST), including many very faint and millisecond pulsars. The survey reveals more electrons in the Milky Way's spiral arms than previously known.
LHAASO's discovery opens up an era for UHE gamma astronomy, prompting scientists to rethink high-energy particle acceleration and propagation mechanisms. The observatory detected 12 stable gamma ray sources with energies up to 1 PeV, revealing the Milky Way is full of PeVatrons.
Researchers discovered that the ZAR1 resistosome forms pentameric oligomers in plant cell membranes, triggering sustained calcium ion influx and immune signaling events. This activation initiates cell death and is dependent on the activity of the calcium-permeable ion channel.
Researchers at the Chinese Academy of Sciences extracted the proton mass radius from experimental data, finding it to be 0.67 ± 0.03 femtometers, which is smaller than the charge radius.
PIF proteins play organ-specific roles in regulating cell division in apical hooks and cotyledons, but not in hypocotyls. Cytokinesis is involved in the apical hook opening, and PIF proteins directly bind to the promoter of BUB3.1, a key regulator of microtubule reorganization during cytokinesis.
The study identifies Knl1 as a constitutive component of the central kinetochore protein in plants, playing an essential role in chromosomal congregation and segregation during mitosis. Deficiencies in Knl1 are linked to defective kernel development.
A recent study published in Nature Climate Change warns that flash flood risk may triple across the Third Pole due to global warming. The study found that one in six glacial lakes pose a high to very high risk to downstream communities, with potential transboundary natural disasters expected to increase.
A recent study published in Nature Astronomy has found evidence for three-dimensional (3D) spin-velocity alignment in pulsars. The research, conducted using the Five-hundred-meter Aperture Spherical radio Telescope (FAST), reveals new insights into the origins of these rapidly rotating neutron stars.
Researchers found that adding aluminum to seawater increases net carbon fixation of marine diatoms by 10-30%, improving the ocean's ability to absorb CO2. This process can significantly increase the ocean's carbon sink capacity and sequester carbon for long periods, aiding climate change mitigation.
A new research discovery reveals an exceptionally diverse tropical seasonal rainforest biota from the Miocene era, with over 250 arthropod families and 78 broadleaf tree species. This find provides insights into the evolution of rainforests and their potential adaptability to a warmer world.
The study revealed key physics behind primary energy release, particle acceleration, and transportation in solar radio bursts. MUSER provides a unique tool for measuring solar magnetic fields and tracing dynamic evolution of energetic electrons.
Researchers identify subnanoscale chemical short-range order (CSRO) in face-centered cubic VCoNi alloy using complete suite of tools and methods. CSRO is linked to mechanical properties and plasticity mechanisms.
Researchers found low-velocity anomalies in six subduction zones, leading to a shift in rupture mechanics and potentially inducing major megathrust earthquakes. The study suggests that these anomalies can increase interplate shear stress, making it easier for earthquakes to occur.
The study unravels the evolutionary and genetic origins of flatfish specialized body plan through comparative genomic analysis. Key findings include significant alteration in genes related to visual perception, immune response, and musculature development.
Researchers at Chinese Academy of Sciences have uncovered the atomic structure of SLAC1, a protein responsible for closing stomatal pores in plants. The discovery sheds light on how plants respond to environmental changes, such as high CO2 levels and drought.
Scientists have discovered a new type of coronal rain forming along open magnetic structures on the Sun, which is facilitated by interchange magnetic reconnection between open and closed magnetic structures. This mechanism triggers thermal instability, leading to cooling and condensation of hot coronal plasma, resulting in coronal rain.
A study by Chinese Academy of Sciences researchers found that China's efforts to achieve a 1.5°C warming limit require significant reductions in carbon and non-carbon emissions, with substantial declines in energy consumption and fossil fuel use. The study also highlights the importance of transitioning to renewable energy sources.
Researchers have made a significant step in understanding dark energy using the eBOSS survey, detecting its existence at a 11-sigma significance. The study employed multi-tracer analysis to mitigate systematics and achieve robust cosmological results.
Researchers mapped the developmental landscape of the mouse hypothalamus, revealing a stepwise strategy for neural progenitors to generate extreme neuronal diversity. The study provides insights into hypothalamic plasticity and potential therapeutic targets for diseases such as anorexia and narcolepsy.
Researchers have made significant progress in understanding the stellar beta-decay rate of 59Fe, which is essential for predicting the yield of 60Fe in massive stars. By measuring this rate, they eliminated a major nuclear uncertainty and found that the yield of 60Fe is 40% less than previously predicted.
Researchers at Chinese Academy of Sciences discover abnormal enhancement of α-particle clustering in uranium isotopes, revealing strong proton-neutron interaction influence on α-decay properties. The study reveals systematics trends and anomalies in α-decay reduced widths for polonium-plutonium nuclei near shell closure.
A team of scientists found that ENSO-related climate variability is expected to increase under global warming due to the amplification of tropical lower tropospheric humidity. This intensification in ENSO-driven atmospheric variability suggests a higher risk of extreme weather events.
Researchers found that prime editors have extremely low off-target effects in plant cells, with editing rates of 0.00%~0.23%. The study suggests designing pegRNAs to minimize off-target sites and eliminates concerns about nonspecific effects from M-MLV RT.
Researchers have programmed microalgae to produce fatty acids of different lengths, creating a more flexible cell factory for producing industrially relevant oils. This breakthrough could lead to the development of designer oils with various fatty acid chain lengths.
Tropical forest soils capture carbon dioxide into organic matter interacting with soil minerals, leading to reduced CO2 emissions. Excessive nitrogen deposition stimulates soil carbon storage by 7-21% in tropical forests.
Researchers uncover a new fossil beetle species from mid-Cretaceous amber, shedding light on the earliest pollinators of flowering plants. The discovery shows that short-winged flower beetles visited angiosperms in the Cretaceous, leading to a direct link between early flowering plants and their insect visitors.
Researchers found two new species, Fossiomanus sinensis and Jueconodon cheni, with characteristics of scratch diggers in the Jehol Biota ecosystem. The animals independently evolved traits to support their digging lifestyle, including shorter limbs and strong forelimbs.
Researchers observed cavitation governing fracture in glasses, revealing self-organized nucleation and growth of nanocavities. Cavitation-induced nanopatterns are common in various glass types, including polymers and silicates.