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Chinese Academy of Sciences Headquarters


Researchers propose new method for large-scale data integration and biomarker identification

A team of researchers has developed a new algorithm to efficiently integrate large-scale microbiome data and identify disease-associated biomarkers. The NetMoss algorithm uses microbial interaction networks to remove batch effects and quantify topological differences, revealing biomarkers linked to multiple diseases.

SourceChinese Academy of Sciences Headquarters·JournalNature Computational Science·DateJun 6, 2022

CAS(ME)3: Next-generation Micro-expression database with depth information and high ecological validity

Researchers have developed CAS(ME)3, a large-scale micro-expression database with depth information and high ecological validity. The database contains 1,109 manually labeled micro-expressions and 3,490 macro-expressions, allowing for more accurate emotional analysis and recognition.

SourceChinese Academy of Sciences Headquarters·JournalIEEE Transactions on Pattern Analysis and Machine Intelligence·TypeExperimental study·DateMay 16, 2022

Massive carbon emission caused marine anoxia and biodiversity loss 304 million years ago

A recent study reveals that massive carbon emission during the Late Paleozoic Ice Age led to anoxic areal extent equivalent to 20% of the seafloor and significant biodiversity loss. The research team used geochemical signals, sedimentology, and climate modeling to simulate the effects of a 300,000-year warming event.

SourceChinese Academy of Sciences Headquarters·JournalProceedings of the National Academy of Sciences·DateMay 5, 2022

Researchers boost rice yield by overcoming trait tradeoff between panicle number and size

Researchers from the Chinese Academy of Sciences have developed a method to overcome the tradeoff between rice yield component traits, including panicle number and size. By modifying the cis-regulatory region of the Ideal Plant Architecture 1 gene, they increased grain yield by 15.9% while maintaining tiller number.

SourceChinese Academy of Sciences Headquarters·JournalNature Biotechnology·TypeExperimental study·DateApr 21, 2022

Automated CAST-R system helps to identify best antimicrobials to fight acute blood infections

Researchers developed an automated system called Clinical Antimicrobials Susceptibility Test Ramanometry (CAST-R) to identify the best antibiotics for treating acute blood infections. The system uses Raman microspectroscopy and machine learning to achieve rapid and accurate results, outperforming conventional methods in just three hours.

Researchers reveal neuronal mechanism controlling anxiety-like behavior and energy expenditure

A recent study revealed the importance of Cav3.1-driven burst firing in the ventromedial hypothalamic nuclei in controlling anxiety-like behavior and energy expenditure following chronic stress. Enhanced burst firing was correlated with increased anxiety-like behavior, reduced food intake, and decreased energy expenditure.

SourceChinese Academy of Sciences Headquarters·JournalMolecular Psychiatry·DateMar 22, 2022

Tropical methane emissions contribute largely to recent changes in global atmospheric methane growth rate

A recent study reveals that tropical terrestrial methane emissions account for over 80% of the observed changes in global atmospheric methane growth rate between 2010 and 2019. This finding underscores the significant impact of methane on climate change, with methane concentrations more than doubling since the pre-industrial era.

SourceChinese Academy of Sciences Headquarters·JournalNature Communications·DateMar 16, 2022

New approach enables background-suppressed tumor-targeted photoacoustic imaging

A research team has proposed a new approach to achieve background-suppressed tumor-targeted photoacoustic imaging, enabling deep-tissue tumor-specific imaging in vivo. The approach uses genetically engineered bacteria to deliver a photoswitchable chromoprotein to the tumor site, eliminating interference from blood background signals.

SourceChinese Academy of Sciences Headquarters·JournalProceedings of the National Academy of Sciences·DateFeb 22, 2022