Add BrightSurf on Google Email

Chinese Academy of Sciences Headquarters


Researchers design high-fidelity Cas13 variants to minimize collateral RNA targeting

Researchers designed high-fidelity Cas13 variants using mutagenesis to reduce collateral effects, demonstrating their feasibility and efficiency in mammalian cells and animals. The most promising variant, hfCas13d, showed marked reduction in off-target genes and no detectable collateral damage, supporting its potential for gene therapy.

SourceChinese Academy of Sciences Headquarters·JournalNature Biotechnology·DateAug 14, 2022

Researchers regulate pore size distribution to improve nanofiltration membrane

A research group developed a novel antifouling nanofiltration membrane by regulating pore size distribution through one-step multiple interfacial polymerization. The resulting membrane exhibits stronger antifouling performance and long-term stability, promising improved robustness in industrial liquid separation.

SourceChinese Academy of Sciences Headquarters·JournalACS Applied Materials & Interfaces·DateJul 27, 2022

Human activity increases likelihood of more extreme heatwaves

Researchers found that greenhouse gases are the primary reason for increased temperatures and will likely continue to be the main cause of hotter temperatures in the future. The study suggests that extreme heatwave events will increase by more than 30 percentage points in coming years, with almost two-thirds caused by greenhouse gases.

SourceChinese Academy of Sciences Headquarters·JournalAdvances in Atmospheric Sciences·DateJul 25, 2022

Newly discovered Liexi Fauna reveals early stage of Great Ordovician Biodiversification Event

The Liexi Fauna discovery provides new evidence for the Great Ordovician Biodiversification Event, featuring a rich array of biomineralized fossils and non-mineralized tissues. The fauna reveals a flourishing Early Ordovician marine ecosystem with diverse organisms and varied lifestyles.

SourceChinese Academy of Sciences Headquarters·JournalProceedings of the Royal Society B Biological Sciences·DateJul 17, 2022

Artificial intelligence enables non-invasive, accurate screening for down syndrome in the first trimester

Researchers developed a convolutional neural network to identify fetuses with Down Syndrome from ultrasound images. The model achieved high accuracy, improving detection by over 15% compared to existing methods. Non-invasive screening could become a convenient and inexpensive tool for early pregnancy diagnosis.

SourceChinese Academy of Sciences Headquarters·JournalJAMA Network Open·DateJul 6, 2022

Fossils confirm early diversification of spiny plants in central Tibet

Researchers have discovered exceptionally rich assemblages of plant spine fossils in central Tibet, confirming an early diversification of spiny plants around 39 million years ago. The findings suggest that a drying and cooling climate may have driven the evolution of physical defense mechanisms against large herbivores.

SourceChinese Academy of Sciences Headquarters·JournalNature Communications·TypeObservational study·DateJul 5, 2022

“Volcano-shaped” trend enables rational design of polysulfide catalysts in lithium–sulfur batteries

Researchers discovered a 'volcano-shaped' relationship between polysulfide adsorption and catalytic activity in lithium-sulfur batteries. This finding modifies the long-standing principle that strong adsorption leads to good catalytic activity, suggesting catalysts should be designed separately to improve performance.

SourceChinese Academy of Sciences Headquarters·JournalNature Catalysis·DateJun 16, 2022

Researchers reveal receptor-specific recognition modes of neuropeptide Y

A team of researchers has determined the cryo-electron microscopy structures of three NPY receptors in complex with the peptide ligand and Gi protein. The study reveals interaction details between different NPY receptors and the peptide, highlighting distinct conformations upon binding to each receptor. This understanding is crucial fo...

SourceChinese Academy of Sciences Headquarters·JournalScience Advances·DateJun 14, 2022

Research discovers neurons that regulate body temperature and social behaviors

A recent study identified Pdyn-expressing neurons in the ventromedial hypothalamus as a novel nucleus controlling homeostatic thermogenesis and social interaction-associated hyperthermia. These neurons respond to cold temperatures, promoting thermogenesis, and also modulate social interactions, leading to increased body temperature.

SourceChinese Academy of Sciences Headquarters·JournalCell Metabolism·TypeRandomized controlled/clinical trial·DateJun 9, 2022