Researchers found increased AGE levels in eyes of people with type 2 diabetes and prediabetes, indicating potential for early detection through lens autofluorescence measurement. A new biomicroscope can detect these levels without invasive procedures.
Recent studies indicate a potential decrease in the rate of new type 2 diabetes cases, although overall prevalence continues to rise. The decline is attributed to improved care and longer survival rates, suggesting that public health initiatives may be contributing to the trend.
The study found that men and women experience different comorbidities as having diabetes or prediabetes, including a higher rate of prediabetes among children. Prediabetic women showed a higher prevalence of osteoporosis and depression compared to men.
A new study found that obesity increases the risk of type 2 diabetes by 5.8-fold, while genetic predisposition and unfavorable lifestyle factors contribute less to the risk, but still play a role in its development. Lifestyle interventions can help delay the onset of T2D among high-risk subjects.
A new study in Diabetologia reveals that shorter individuals are at a higher risk of developing type 2 diabetes. The research found that for every 10cm increase in height, the risk of type 2 diabetes decreased by 41% in men and 33% in women, adjusted for age and other factors.
A healthy lifestyle is associated with a 75% lower risk of developing type 2 diabetes, compared to the least healthy lifestyle. In individuals with type 2 diabetes, a healthy lifestyle also reduces cardiovascular disease and death risk by 56% and 52%, respectively.
Mothers with pre-pregnancy diabetes are at a four to five times increased risk of stillbirth. High maternal blood sugar levels and BMI emerged as key risk factors for increased stillbirth risk, particularly in babies born small or large for gestational age.
A new study finds that diabetes confers a greater excess risk of heart failure in women than men, with type 1 diabetes associated with a 47% higher risk. The study suggests several potential explanations for this difference, including sex differences in diabetes management and cardiovascular risk factors.
A UK study published in Diabetologia found that obesity during pregnancy is associated with a 3.5 times increased risk of type 2 diabetes in the child, while being overweight increases this risk by 40%. The study suggests strategies to reduce obesity and overweight in women of reproductive age are urgently needed.
A new study published in Diabetologia found that type 2 diabetes in midlife is associated with a 30% increased risk of serious brain artery blockage leading to stroke. Additionally, individuals with T2DM at ages 40-59 years had double the risk of cerebral occlusion and a 30% higher risk of cerebral infarction.
A new study published in Diabetologia found that women who develop gestational diabetes (GDM) during pregnancy are at double the risk of cardiovascular disease (CVD) compared to those without GDM. The study also revealed that this increased risk remains even if women with GDM do not go on to develop type 2 diabetes.
A recent study published in Diabetologia found that three-quarters of individuals with type 2 diabetes who underwent Roux-en-Y gastric bypass surgery experienced diabetes remission within one year. The research also identified predictors for success, including lower glycated haemoglobin levels and male patients, as well as a reduced ri...
A recent study by researchers at The Ohio State University Wexner Medical Center found that following heart health guidelines can significantly reduce the risk of developing diabetes. Participants who met the recommended ranges for four or more of the seven factors had a 70% lower risk of developing diabetes over the next 10 years.
A new study published in Diabetologia found that type 2 diabetes is associated with a decline in verbal memory and fluency over 5 years in older adults. In contrast to previous research, the study did not find a direct link between brain atrophy and cognitive decline in people with T2D.
A new study found a significant increase in type 1 diabetes cases across Europe, with rates rising by 3.4% per year. The study's findings have important implications for healthcare planning and delivery, highlighting the need for improved blood sugar control and increased support services.
Researchers found that non-invasive skin autofluorescence measurement can predict future risk of type 2 diabetes, cardiovascular disease, and mortality. A single measurement was associated with a 3-fold increase in risk of type 2 diabetes or CVD.
A new study published in Diabetologia found that children born large for gestational age (LGA) and born to mothers with gestational diabetes are almost three times as likely to be obese as children born a normal size to diabetes-free mothers. Breastfeeding was associated with a reduced risk of obesity in most children.
A large prospective cohort study found that higher levels of prolactin in women are associated with a lower risk of developing type 2 diabetes. Women with the highest 25% of prolactin levels were 27% less likely to develop T2D than those in the lowest 25%. The association was similar regardless of menopausal status and other risk factors.
The new guidelines update previous recommendations, prioritizing patient-centric care, medication adherence, and lifestyle management. They also highlight the importance of metabolic surgery, metformin as first-line therapy, and personalized medication selection based on patient preferences and comorbidities.
A Japanese study found that increased fasting glucose, higher BMI, and impaired insulin sensitivity were detectable up to 10 years before the diagnosis of diabetes as well as prediabetes. The study suggests that elevated metabolic markers for diabetes may be detectable more than 20 years before its diagnosis.
A new study published in The Lancet found that lorcaserin, an appetite-suppressant drug, decreases the risk of developing diabetes and increases the rates of remission of high blood sugar in obese and overweight patients. Lorcaserin also reduces the risk of kidney complications due to diabetes.
A new study reveals that low-calorie sweeteners can change the types of bacteria found in the gut, leading to impaired regulation of glucose levels. The research found a significant reduction in beneficial bacterial species and an increase in opportunistic gut bacteria.
A new study found that 21% of individuals with insulin-treated diabetes diagnosed after age 30 have severe insulin deficiency, characteristic of late-onset type 1 diabetes. These patients often experience delays in diagnosis and treatment due to misdiagnosis as type 2 diabetes.
A new hybrid closed-loop insulin delivery system was compared to sensor-augmented pump therapy for blood sugar control in patients with poorly controlled type 1 diabetes. The study found that the hybrid closed-loop system achieved significantly better glucose control and reduced the risk of hypoglycaemia.
A nationwide study found that people with diabetes from deprived backgrounds are twice as likely to be admitted to hospital for major cardiovascular events. Socioeconomic inequalities persist, despite improvements in overall cardiovascular disease outcomes.
Researchers found that lixisenatide slowed the progression of kidney damage in patients with macro-albuminuria and type 2 diabetes. The study showed a statistically significant reduction in urinary albumin-to-creatinine ratio and a borderline significant reduction in risk of incidence of macroalbuminuria.
The study found large regional variations in diabetes prevalence, with North America and the Caribbean having high current rates, while Africa has low rates despite moderate obesity. If obesity rates are reduced by 25%, millions of cases of diabetes can be prevented, especially in Africa.
The BCG vaccine, used to prevent tuberculosis, can reduce blood sugar levels in people with advanced type 1 diabetes by mimicking microbial exposures. The vaccine appears to reset abnormal metabolic functions, boosting the immune system to consume sugar and reduce blood glucose levels over time.
Researchers found that 79% of insulin temperature logs contained deviations from the recommended range, with fridge storage being the biggest issue. This can lead to reduced potency and variability in dosing for people with diabetes, highlighting the need for proper storage and monitoring practices.
A large observational study found that adults with type 2 diabetes are at greater risk of dying from cancer, particularly obesity-related cancers. Non-obesity related cancers also pose a significant threat to individuals with type 2 diabetes.
A new study published in The Lancet found that albiglutide, a GLP-1 receptor agonist, reduces the risk of major adverse cardiovascular events by 22% in patients with type 2 diabetes and established cardiovascular disease. This result is comparable to traditional cardiovascular drugs.
A large observational study found that individuals with diabetes are at a higher risk of developing certain cancers, including colorectal and breast cancer. The study also showed that people with diabetes who are diagnosed with cancer have poorer survival rates compared to those without diabetes.
A new study found that younger age at diagnosis, higher body mass index, and a maternal family history of diabetes are associated with faster disease progression in type 2 diabetes. The research used data from the UK BioBank to identify these factors and their impact on disease progression.
A new study found increasing infection rates for urinary tract infections, sepsis, and skin infections among people with diabetes in the USA. Rates of infection-related hospitalisations increased by 52% between 2010 and 2015 compared to the general population.
A new study has found a strong association between diabetes and an increased risk of developing osteoarthritis, rheumatoid arthritis, and osteoporosis. People with diabetes were 33% more likely to suffer from osteoarthritis than their counterparts without diabetes.
Research reveals that women with versus without prediabetes experience significantly larger adverse differences in cardiometabolic health compared to men. Women with prediabetes had higher blood pressure, worse cholesterol profiles, and increased inflammation before the onset of type 2 diabetes.
Testosterone treatment over 10 years can improve or reverse type 2 diabetes in men with low testosterone, leading to significant weight loss. The study found that average fasting blood glucose levels decreased and HbA1c levels fell in the testosterone-treated group, while worsening in the control group.
Research shows that weight gain between childhood and adulthood increases type 2 diabetes risk more than a stable high body mass index. Children who were overweight at age 10 and remained so have lower T2D risk compared to those who were normal weight but became overweight later in life.
Researchers found that SHBG levels at baseline can predict insulin resistance years later in both men and women. Lower SHBG levels are associated with higher insulin resistance, a precursor to type 2 diabetes.
A large meta-analysis of over 191,000 postmenopausal women found that early menopause and premature ovarian failure are associated with a higher risk of developing type 2 diabetes. Women who begin menopause before age 40 are 50% more likely to develop the disease than those with normal menopause between ages 45-55.
A new study suggests that weight loss can put type 2 diabetes into remission by improving pancreatic beta cell function. Nearly half of participants who lost fat from around the liver and pancreas achieved diabetes remission, compared to six in the control group.
A new study reveals that gastric bypass surgery reduces all-cause mortality risk by 49% and cardiovascular disease risk by 34% in obese patients with type 2 diabetes. However, it also increases the risk of anaemia, malnutrition, and psychiatric diagnoses.
A recent study found that people with both diabetes and dementia are 67% more likely to die after experiencing dangerously low blood sugar. The researchers call for strategies to prevent and reduce hypoglycaemia in older adults with these conditions, prioritizing continuous glucose monitoring devices.
A new study reveals that diuretic drug use in individuals with type 2 diabetes is associated with a significantly increased risk of serious problems in their lower limbs, leading to amputation. The research found that diuretics should be used cautiously in patients at risk of amputations.
Research by Professor Wing Hung Tam and colleagues found that excessive or inadequate weight gain during pregnancy is associated with increased risk of cardiometabolic problems in children aged 7, including higher blood pressure and poor blood sugar control. The study suggests balancing weight gain to minimize adverse outcomes while co...
Research finds cardiorespiratory fitness, high-intensity physical activity and low sedentary time all lower type 2 diabetes risk. The study, published in Diabetologia, suggests that a combination of these traits may be more beneficial than individual components.
A new study published in Diabetologia reveals that diabetes is a significant risk factor for all-site and site-specific cancers, with a higher risk in women than men. Women with diabetes have a 27% higher risk of all-site cancer compared to women without diabetes.
A study has found structural and functional changes in muscles of young adults with Type 1 diabetes, leading to reduced metabolism and increased risk of disability.
A new study published in Diabetologia found that the earlier a person is diagnosed with type 2 diabetes, the higher their risk of death from heart disease and stroke. However, an earlier diagnosis was also associated with lower mortality rates due to cancer.
A new study of 5,000 older people in the UK found that those with diabetes experience steeper rates of cognitive decline compared to those with normal blood sugar control. The study suggests that efforts to delay diabetes onset and control blood sugar levels may prevent subsequent progression of brain function decline.