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Diabetologia


New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes

A new study published in Diabetologia found that healthy plant-based diets, including fruits, vegetables, and legumes, are linked to a lower risk of developing type 2 diabetes. The study analyzed metabolite profiles and diet indices from over 10,684 participants, revealing unique multi-metabolite profiles associated with healthy plant-...

SourceDiabetologia·JournalDiabetologia·DateApr 8, 2022

Optimizing indoor light conditions to mimic the natural light-dark cycle could help mitigate adverse metabolic effects of extended periods of exposure to indoor lighting

A study found that bright light during daylight hours and dim light in the evening improves glucose metabolism, thermoregulation, and energy expenditure. In contrast, a dim day with bright evening led to reduced postprandial glucose levels despite unchanged insulin levels.

SourceDiabetologia·JournalDiabetologia·DateFeb 2, 2022

Review concludes managing weight and preventing obesity in people with type 1 diabetes is a difficult but not impossible balance

A new review concludes that people with type 1 diabetes can manage their weight, but more research is needed to understand the specific needs of this patient group. The review explores strategies such as nutrition education, adjunct therapies like metformin and GLP-1 receptor agonists, and obesity surgery.

SourceDiabetologia·JournalThe Lancet Diabetes & Endocrinology·DateSep 30, 2021

COVID-19 lockdowns have major impact on diabetes control, international study finds

A comprehensive analysis of 33 studies reveals that COVID-19 lockdowns lead to improved blood sugar control in individuals with type 1 diabetes, while glycaemic control deteriorates and weight gain increases among those with type 2 diabetes. The study suggests that lockdown measures may have allowed people with type 1 diabetes to bette...

SourceDiabetologia·JournalDiabetology & Metabolic Syndrome·DateSep 29, 2021

Studies using ‘model’ organs show how SARS-CoV-2 can infect wide range of cell types and even change function of cells, including the insulin-producing cells of pancreas

Researchers used human pluripotent stem cells and organoids to study SARS-CoV-2 infection, finding that it can infect multiple cell types, including lung, colon, heart, liver, and pancreatic cells. The virus alters cellular function, including reducing insulin production in pancreatic beta cells.

Lifestyle changes and adhering to treatment targets can greatly reduce excess dementia risk in people with type 2 diabetes, study from UK and the Netherlands suggests

A large study of over 88,000 participants found that addressing key risk factors such as smoking, diet, and blood pressure can lower dementia risk in those with type 2 diabetes. The study also showed improvements in cognitive function and brain structure with greater adherence to treatment targets.

SourceDiabetologia·JournalDiabetes Care·DateSep 28, 2021

Study of nearly 3 million people finds ‘healthy’ obese people more likely to develop heart failure than those of normal weight—but are not at greater risk of heart attack or stroke

Researchers analyzed data from nearly 3 million adults and found that those with 'metabolically healthy obesity' had a higher risk of developing heart failure and atrial fibrillation. However, they were not at increased risk for heart attacks, strokes, or cardiovascular deaths.

SourceDiabetologia·JournalDiabetes Obesity and Metabolism·DateSep 27, 2021

Women with diabetes less likely to receive comprehensive cardiovascular prevention than men, international study finds

An international study involving almost 10,000 patients with type 2 diabetes found that women are less likely to reach recommended treatment targets for cardiovascular prevention, such as statins and blood pressure medications. However, women were less likely to experience adverse cardiovascular outcomes apart from stroke.

SourceDiabetologia·JournalDiabetologia·DateSep 26, 2021

New study reveals that children of mothers with diabetes during pregnancy have an increased risk of eye problems

A new study published in Diabetologia found that children of mothers with diabetes before or during pregnancy are more likely to develop high refractive error (RE), including long and short-sightedness. The study analyzed data from over 2.4 million births in Denmark and found a significant association between maternal diabetes and an i...

SourceDiabetologia·JournalDiabetologia·DateAug 17, 2021

New study shows diabetes is associated with a significant increase in the risk of hospitalisation and mortality caused by infections

A new study found that individuals with diabetes are significantly more likely to be hospitalized and have a greater risk of dying from infections. The research showed that the risk was more pronounced in younger adults with diabetes and black people, with an increased likelihood of both common and rare infections. This association bet...

SourceDiabetologia·JournalDiabetologia·DateAug 4, 2021

High-intensity interval training combining rowing and cycling improves insulin sensitivity, body composition and cardiorespiratory fitness in obesity and type 2 diabetes

A new study found that high-intensity interval training (HIIT) combining cycling and rowing improves insulin sensitivity and reduces blood sugar levels in individuals with obesity and type 2 diabetes. The study also showed improvements in body composition, including a reduction in fat mass and an increase in muscle mass.