A study published in Archives of General Psychiatry suggests that a loss of healthy bacteria due to modern sanitation may contribute to the increasing rates of depression. Experiments are being conducted to test treatments using properties of these beneficial microorganisms, aiming to improve emotional tolerance.
Researchers at Emory University School of Medicine have adapted gene chip microarray technology to the study of glycans, using an approach called 'shotgun glycomics.' This technique allows for the separation and analysis of thousands of glycans, enabling researchers to test what sticks to them. The method has been used to identify a mo...
A recent study published in Neurology found no significant difference in IQ scores between breastfed and non-breasted babies of mothers taking epilepsy drugs. The study, which followed 194 pregnant women taking one epilepsy drug, suggests that breastfeeding may not have a negative impact on cognitive skills.
The structure of Lassa virus protein reveals how it evades the host's immune system and hijacks infected cells' machinery. Scientists discovered a unique mechanism called cap-stealing, where the virus steals the host cell's RNA cap to suppress interferon production.
A study led by Emory University School of Medicine found that patients with low health literacy are more likely to be hospitalized for heart failure. Adults with lower REALM-R scores were 55% more likely to be admitted, with those from low-income backgrounds and without a college education facing higher risks.
Researchers found that individuals with poor sleep quality had higher levels of inflammatory markers, including C-reactive protein, even after adjusting for known risk factors. Chronic lack of sleep may contribute to cardiovascular mortality, but the exact mechanism remains uncertain.
Yerkes researchers are presenting various studies on neuroscience topics including social bonding, addiction, neurodegenerative diseases and memory. Researchers like Larry Young, Leonard Howell and Yoland Smith are sharing their findings on oxytocin, stimulant addiction and cell death in neurodegenerative diseases.
A significant genetic deletion on chromosome 17 has been identified as a risk factor for autism spectrum disorders and schizophrenia. The study found that patients with this deletion were at least 13.58 times more likely to develop ASD or schizophrenia.
The study found that planning complex tasks was key for making sophisticated hand axes, suggesting higher cognition involved. The results point to links between tool-making and language evolution, with the brain's Broca's area playing a role.
Researchers conclude that cutting mosquito surveillance would lead to exponential increases in human cases and health costs. A delayed response can result in drastically escalated costs, with some estimates suggesting a 10-fold increase. The study highlights the need for sustained funding of mosquito surveillance programs.
Researchers at Emory University found that monarch butterfly females prefer milkweed plants with high levels of cardenolides to lay eggs on, reducing parasite infection in their offspring. This behavior is thought to be a form of self-medication, and the study's findings may have implications for human health.
Researchers identified a compound called CIQ that selectively enhances NMDA receptor function, targeting specific subunits believed to contribute to schizophrenia symptoms. This approach aims to compensate for deficits in patients with the condition by manipulating receptor signaling.
Researchers emphasize Couples Voluntary Counseling and Testing (CVCT) as a proven method to decrease HIV/AIDS rates in Africa. The approach identifies undiagnosed individuals, allowing for targeted interventions before new infections occur.
Research by sociologists Ellen Idler and Julie Phillips found significant increases in middle-aged suicide rates, particularly among unmarried individuals and those without a college degree. The study suggests that chronic diseases and substance abuse may be contributing factors to the rising trend.
Researchers at Emory University School of Medicine have found that deleting a certain gene in mice can improve their learning and memory abilities. The RGS14 gene, which is primarily active in one region of the hippocampus, appears to limit some forms of learning and memory when present.
Chronic diseases like heart disease, cancer, and diabetes threaten the health and economies of nations worldwide. The authors assert that global cooperation is crucial to reduce these diseases, citing examples of successful connections in reducing chronic disease.
Researchers have discovered two coordinated dance moves performed by skeletons inside neurons during long-term potentiation, a process linked to learning and memory. This finding provides insight into developmental disorders such as Williams syndrome, which affects cognitive strengths and weaknesses.
A recent study found that over a quarter of acute care visits in the US are made to emergency departments, instead of personal physicians. This shift is attributed to primary care doctors' packed schedules and low reimbursement rates, which limit their ability to provide timely access to care.
Researchers have found evidence that ancient Nubians regularly consumed tetracycline, a powerful antibiotic, most likely through their beer. This discovery suggests that the art of making antibiotics was common practice nearly 2,000 years ago and challenges traditional views on the origins of modern medicine.
Researchers found Ashkenazi Jews have higher genetic diversity than previously thought, with evidence of interbreeding with European and Middle Eastern populations. Only a minority of disease-related genes show signs of positive selection, suggesting most traits arose through random genetic drift.
Researchers have identified a mechanism by which disulfiram, a decades-old treatment for alcoholism, prevents cocaine relapse. A newer drug, nepicastat, works through the same mechanism and shows promise in treating cocaine addiction.
Scientists have identified a population of cells enriched with the capacity to regenerate blood vessels, which show promise in treating cardiovascular disease. These cells, isolated from human blood or bone marrow, can support the growth of nearby blood vessels and enhance blood flow.
Researchers have discovered a potential new treatment for fragile X syndrome by targeting phosphoinositide-3 (PI3) kinase inhibitors. These drugs can correct defects in neurons and restore normal protein production at synapses, suggesting improved learning and cognition in individuals with the condition.
Researchers have demonstrated the use of iron oxide nanoparticles to deliver antibodies to implanted brain tumors, enhancing tumor visibility via MRI while killing cancer cells. The particles also show potential for targeted therapy against glioblastoma multiforme, a common and aggressive primary brain tumor.
Chagas disease affects 10-12 million people in Latin America, killing 15,000 annually. Dogs can spread the disease and may help control it by acting as sentinels for health officials.
A new study reveals that low vitamin D levels can predict the development of Parkinson's disease, with individuals having the lowest levels being three times more likely to develop the condition. Researchers are calling for public health authorities to consider raising the target vitamin D level above the current recommended level.
A study by Emory University found that sewage overflows in urban creeks and streams increase the risk of West Nile virus transmission, particularly in lower-income neighborhoods. The analysis showed a seven times higher risk for residents near affected areas compared to other parts of the city.
Researchers developed multicolor quantum dot staining to identify Reed-Sternberg cells, characteristic of Hodgkin's lymphoma. This method allows for rapid detection and identification of rare malignant cells from heterogeneous tissue specimens.
A new study reveals that nearly every newborn has a new transposon insertion in their genome, suggesting a significant increase in genetic instability. Transposons are also implicated in tumor formation and can inactivate tumor suppressor genes.
Researchers have developed an animal model that demonstrates the initial stages of atherosclerosis can be predicted by disturbed blood flow. The study identifies genes turned on or off in response to disrupted flow, providing new insights into how exercise may protect against the disease.
Researchers found that 9-month-old babies can recognize 'more than' or 'less than' relations across numbers, sizes, and durations of objects. This suggests that humans may be born with a generalized system of magnitude that helps them make predictions about the world from an early age.
Researchers have identified a unique gene pattern in white blood cells of tolerant kidney transplant recipients, which may enable them to stop taking immunosuppressive drugs. The study found that B cell genes play a crucial role in maintaining tolerance to transplanted organs.
The commentary emphasizes the need for improved TB diagnosis and treatment access, surveillance, and investment in new drugs, diagnostics, and a vaccine. Migrants face significant health disparities due to inadequate treatment and poor public health infrastructure.
A consensus statement recommends chromosomal microarray (CMA) as the new standard practice for genetic evaluation of children with unexplained developmental delay, autism or birth defects. CMA consistently has a diagnostic yield of 15 to 20 percent, compared to five percent with G-banded karyotyping.
Researchers at Emory University have discovered that simple peptides can organize into bi-layer membranes, a 'missing link' between pre-biotic Earth's chemical inventory and the scaffolding essential to life. This finding may also shed light on protein assemblies related to Alzheimer's disease, Type 2 diabetes, and other serious ailments.
Researchers have discovered prehistoric fish trails, made by the ancient species Notogoneus osculus, in Wyoming's former Fossil Lake. The study provides evidence that fish were able to survive on the lake bottom despite low oxygen levels.
Scientists discovered that brain tissue produces a natural form of the clot-busting drug tPA, which acts as a neuroprotectant and may prevent strokes. The finding suggests a potential new approach to preventing ischemic stroke by prolonging the effects of naturally produced tPA.
The experimental immunosuppressive drug belatacept has been shown to better preserve kidney function and prevent graft rejection in kidney transplant recipients. A two-year study of the BENEFIT trial found that patient and graft survival rates were similar among the belatacept, cyclosporine, and control groups.
A study published in JAMA analyzed US government data and found that consuming more added sugar increases cardiovascular disease risk factors. The study suggests reducing daily added sugar intake could be beneficial for long-term health.
Researchers found that fragile X protein (FMRP) regulates adult neurogenesis, a process crucial for learning and memory. FMRP dysregulation leads to defective neural maturation and reduced new neurons, contributing to learning disabilities associated with fragile X syndrome.
Researchers found that four HIV anti-drugs inhibit XMRV replication, potentially offering a new treatment for prostate cancer and chronic fatigue syndrome. Combination therapies may also delay or prevent the virus from mutating into drug-resistant forms.
Physicist Garrett Lisi proposed a 'theory of everything' centered on the enigmatic E8, but Emory mathematician Skip Garibaldi and colleague Jacques Distler found fatal flaws in its math. The resulting paper shows that E8's unique structure cannot unify the universe's forces as Lisi claimed.
Researchers found that adding chymase inhibitors to ACE inhibitors significantly boosted recovery of heart function in animals after a heart attack. This could lead to improved treatments for people with high blood pressure, heart failure, and other conditions.
Research at Emory University School of Medicine found that high phosphate diet promotes tumor formation and growth in skin cancer, while restricting phosphate may prevent cancer. The study suggests that altered levels of phosphate could tip the balance of chemical reactions influencing cancer development.
A study published in Immunity reveals that immune cells' signals can interfere with the ability of intestinal cells to regenerate, leading to hyper-activation of growth and increasing the risk of colon cancer. Interfering with a protein called dickkopf 1 may aid in controlling inflammatory bowel diseases.
A recent study found that new chemotherapy drugs for metastatic colorectal cancer can increase life expectancy by 6.8 months, but at a cost of $37,100 per patient. The cost-effectiveness of these treatments is disputed, with the study estimating a cost of $99,100 per quality-adjusted life year gained.
Emory physicians report successful outcomes from 21 patients with left main coronary artery blockages treated using hybrid revascularization. The procedure combines coronary artery bypass surgery and PCI, resulting in no major adverse events. A large-scale clinical trial is planned to assess intermediate and long-term outcomes.
Researchers found that late-stage melanoma treatment for people over 65 years old results in substantial economic burdens, with average monthly charges ranging from $902 to $3,933. Early detection and treatment can significantly reduce these costs by up to 40-65%.
Researchers found that patients with larger volumes of epicardial fat tend to have more dangerous atherosclerotic plaques, which can lead to active buildup in coronary arteries. The study also showed that epicardial fat volume correlates with ischemia during nuclear stress tests.
Emory chemists develop most potent homogeneous catalyst for water oxidation, a crucial component for clean hydrogen fuel. The cobalt-based catalyst surpasses previous WOCs in selectivity, stability, and speed.