Molly Schumer and Bérénice Benayoun are the 2019 recipients of the Rosalind Franklin Young Investigator Award. Schumer investigates hybridization in non-mammalian organisms, while Benayoun explores genomic regulation and aging in humans. The award recognizes outstanding genetics research.
Anne Villeneuve, PhD, receives the 2019 Genetics Society of America Medal for her groundbreaking research on meiosis and chromosome inheritance. Her work has significantly impacted our understanding of major aspects of the meiotic program.
Michael Snyder received the 2019 George W. Beadle Award for his contributions to systems biology, including the development of widely-used technology for simultaneous gene analysis. His work has enabled the tracking of RNA molecules, proteins, and genes in humans, paving the way for personalized medicine.
Daniel Hartl receives the 2019 Thomas Hunt Morgan Medal for his influential contributions to experimental and theoretical genetics research, combining mathematical models with cutting-edge techniques. His work explains how DNA mutations are passed through generations, influencing species divergence.
Bruce Weir receives the 2019 Elizabeth W. Jones Award for Excellence in Education, recognizing his 40-year history of training researchers in statistical analysis methods. His work includes the Summer Institute in Statistical Genetics and the Genetic Data Analysis textbook, which have trained thousands of professionals worldwide.
A new analysis of an aggregated set of family trees suggests that the heritability of life span is well below past estimates, likely no more than seven percent. This finding could be due to assortative mating, where people select partners with similar traits, including longevity.
A nationwide genomic study of 800 Danish high school students found that the population is genetically similar, with subtle traces of historical impact on genetic variation. The study suggests that people have mixed freely between different parts of the country, leading to a relatively homogeneous population.
The Fonni's Dog genome study sheds light on the history of Sardinia's fiercely protective canine breed, tracing its development through unregulated selection for behavior. The research also highlights the potential of isolated dog breeds as a powerful resource for finding genes that influence health and behavior.
Researchers found that genetic clustering of southern African populations is closely tied to the ecogeography of the Kalahari Desert region. The study analyzed genome-wide data from 21 KhoeSan groups and identified five primary ancestries, suggesting a geographically complex set of migration events.
Decades of research on nearly 200,000 survivors and their children reveal cancer rates are not as dire as previously thought. Cancer incidence among survivors was only 10% higher than non-exposed populations, with most receiving a relatively modest dose of radiation.
A new rat study suggests that a specific strain of gut microbiota may reduce colon cancer risk and increase survival rates. The research found that rats with LEW microbiota developed significantly fewer tumors than those with other strains, providing new insight into the role of gut microbiota in cancer development.
A new study has found a way to starve tumors of their blood supply by inhibiting the replenishment of an intracellular substrate needed for vascular endothelial cells to respond to pro-angiogenic signals. This approach limits the growth of new blood vessels and enhances the effectiveness of therapy.
Researchers have identified a possible target for a new therapy for children with primitive neuroectodermal tumors (PNETs), the most aggressive type of brain cancer in kids. The study found that inhibiting MEK activity is essential for these tumors to grow, paving the way for potential new treatment options.
A new study has revealed multiple leads for pursuing potential treatments for Alzheimer's disease by targeting a structural flaw in brain cells. The researchers found that the tau protein aggregates in the brains of patients disrupt the lamin nucleoskeleton, leading to DNA relaxation and gene activation.
Researchers studied Euplotes focardii's genes and proteins for survival in cold, oxygen-rich waters. The organism produces protective proteins against oxidative stress and adapts quickly through flexible RNA decoding.
Researchers use roundworms to identify chemicals that can delay aging effects across multiple organisms. Thioflavin T, a commonly used lab dye, is found to lengthen lifespan in various species.
Researchers analyzed firefly flash signals to understand how new mating signals arise through evolution. They found variations in luciferase and opsin genes didn't correlate with signal color changes, suggesting natural selection may be acting on unknown DNA sequences.
A new mouse study shows that diet response is highly individualized and dependent on genetic composition. The researchers found that different mice strains responded differently to various diets, including Western, Mediterranean, and ketogenic diets.
Researchers have developed a system to quickly screen millions of yeast cells for protein aggregates, offering new ways to explore their causes and potential therapies. The technology was used to study prions, Huntington's disease, and prion-switching, providing insights into the toxic effects of misfolded proteins.
A team of researchers has identified an enzyme called Aurora kinase that plays a key role in the regeneration process of single-celled organisms like Stentor. By inhibiting this enzyme, they were able to speed up the healing process without any negative side effects.
Researchers found cavefish have high body fat levels and insulin resistance but remain healthy. They may hold the key to understanding human diseases like non-alcoholic fatty liver disease and type 2 diabetes.
Researchers are using multidisciplinary approaches to genetically improve disease resistance, flooding tolerance, and cell wall composition in sorghum. This work aims to maximize the usefulness of sorghum as a bioenergy crop while minimizing input requirements.
Researchers have identified 10 genetic mutations that can confer resistance to methotrexate, a chemotherapy agent, using a new 'back-to-the-future' approach combining traditional and deep sequencing techniques. This breakthrough offers potential leads for making the drug more reliable.
A study reveals that viruses have driven protein adaptation in humans and other mammals, with 30% of all protein adaptations since humans' divergence from chimpanzees being influenced by viruses. This discovery sheds light on the impact of viruses on cellular machinery and could lead to new therapeutic leads against viral threats.
Whole-genome gene expression and methylation data offer more predictive power than commonly-used clinical information in breast cancer survival predictions. Combining these data with clinical information improves predictions, suggesting a promising genomic approach for future clinic applications.
Non-African humans inherited marginally lower fitness due to Neanderthal inheritance, with estimated 40% reduction in reproductively fit individuals. The study suggests that these harmful gene variants continue to reduce the fitness of some populations today.
A study in GENETICS identifies the first gene associated with temperature-dependent sex determination in reptiles, highlighting the role of genetic variation and climate change. The research found that a specific DNA sequence variation at the CIRBP gene influences sex ratio in snapping turtles.
Sequencing hundreds of wine yeast strains revealed low genetic diversity and high levels of inbreeding, making it challenging to develop improved wine yeasts. Scientists hope to introduce new genes from diverse strains to create hybrids with unique flavor profiles.
The GSA Trainee-Organized Symposia program aims to advance knowledge and encourage exchange among early career geneticists. Newly funded events focus on topics such as genomics of adaptation to human contexts, non-academic career choices, and ribosomal DNA research.
The Genetics Society of America is announcing its inaugural class of PALM Network Spring 2016 Fellows. These fellows are working with mentors to develop and implement evidence-based active learning strategies in their classrooms, aiming to catalyze enduring change in teaching culture at their institutions.
A molecule has been identified that promotes a sleep-like state in nematode worms, which is similar to the sleep of humans and other mammals. The protein VAV-1 regulates this process and is also involved in maintaining normal amounts of EGFR in the neuron.
Detlef Weigel has made significant contributions to the field of genetics, including the identification of florigen and development of genomic tools. He is recognized for his tireless service to the community and his ability to excel science.
Researchers discovered that Dark-fly has a competitive advantage in reproduction over its wild-type counterpart when bred in the dark. The team sequenced the genome of Dark-fly and identified 28 genetic regions responsible for its unique adaptations, including genes involved in pheromone synthesis and circadian rhythms.
Susan E. Celniker has made significant contributions to the field of genetics, including sequencing and annotation of the Drosophila genome. Her work has enabled proteomic studies and developed computational tools for genetics researchers.
Bill Wood has been awarded the Elizabeth W. Jones Award for Excellence in Education for his sustained impact on genetics education, including innovative pedagogical approaches and high-quality undergraduate science education. The award recognizes his leadership in developing evidence-based reflective teaching and active learning.
Nancy Kleckner has made significant contributions to understanding chromosomes and mechanisms of inheritance. Her work has transformed methodology, combining traditional genetic approaches with molecular biology and microscopy.
A new study identifies genetic influences on anxiety in chickens that may also apply to mice and humans. The research found that genes linked to anxiety in chickens were associated with similar behaviors in mice, while some were connected to schizophrenia or bipolar disorder in large human studies.
A new study using mathematical models estimates that gene replacement can spread quickly through populations, potentially eradicating diseases like malaria. However, the speed and efficiency of this biological control strategy also bring significant risks of unintended consequences.
The Genetics Society of America (GSA) is supporting workshops organized by students and postdocs to broaden interest in genetics. These trainee-organized symposia aim to advance knowledge, encourage exchange, and further the GSA mission.
The Genetics Society of America is a founding member of the Plant Science Research Network, which aims to unite the plant science community and promote collaborative research. The network will support new collaborations, foster data exchange standards, and prepare graduate students for diverse careers.
The Genetics Society of America has awarded prizes to undergraduate and graduate students who presented research on Caenorhabditis elegans at the recent meeting. The awards recognized innovative work in various fields, including cell biology, development and evolution, gene regulation and genomics, neurobiology, and physiology.
A single genetic mutation in the tga1 gene led to the formation of naked kernels, allowing for easier consumption. This discovery provides insights into the rapid evolution of corn traits through minor genetic alterations.
The study analyzes 100,000 Californians' health records and genetic data to track down genetic contributions to disease. Researchers have identified genetic variants linked to various diseases, including prostate cancer, allergies, and diabetes.
A new study uses massively parallel gene function assays to characterize nearly 2000 BRCA1 variants, providing a potential solution for sorting out harmful and harmless variants. The approach demonstrates promise but is not yet ready for use in the clinic.
The Genetics Society of America has awarded the DeLill Nasser Award to ten early-career scientists, providing travel grants to attend conferences that enhance their career. The award recognizes excellence in genetics research and supports the professional development of recipients.
The Genetics Society of America has awarded travel grants to 15 undergraduate students to present their research findings at the 20th International C. elegans Meeting. Recipients include students from institutions such as Pennsylvania State University, Washington State University, and Rutgers University.
The Genetics Society of America presented 14 early career researchers with GSA poster awards for their outstanding contributions to fungal genetics. The winners, including graduate students and postdoctoral scientists, showcased innovative research in various fields.
The Genetics Society of America awarded nine young researchers for their innovative work on fruit fly models, shedding light on human genetics diseases. The winners showcased promising contributions to the field, including studies on gene expression and chromatin state in Drosophila development.
A new study published in the Genetics journal estimated that humans carry an average of one to two recessive disease mutations, which can cause severe genetic disorders or prenatal death. The study used a unique community's detailed family histories and genealogical records to estimate the number of mutations per person.
Researchers identified 18 genetic variants associated with maritime pine tree survival under climate stress, improving forecasts of forest growth and reforestation efforts. These findings demonstrate the importance of genetic data in managing biodiversity and commercial forestry amid a changing climate.