Wellness coaching, led by Mayo Clinic resiliency expert Matthew Clark, helps individuals identify personal values and desires for change. The coaching approach recognizes patients' strengths to make positive lifestyle changes, resulting in improved overall quality of life, mood, and perceived stress.
Over-the-counter enzyme supplements can aid digestion, reduce inflammation, and even have anti-cancer effects. However, evidence is limited, and potential side effects include gastrointestinal upset and increased risk of bleeding in certain individuals.
A new algorithm has been developed to diagnose pediatric patients with suspected appendicitis, reducing the need for computed tomography (CT) scans. The study found that CT utilization decreased by over 50% after implementation, without affecting diagnostic accuracy.
The Mayo Clinic is leading a collaborative effort to standardize safe imaging protocols for children, proposing three child-centered measures for accreditation: The Right Exam, The Right Way, and The Right Radiation Dose. These protocols aim to reduce harm and improve the quality of care for pediatric patients.
Researchers found that patients treated with proton therapy had significantly higher disease-free survival rates (72% vs. 50%) compared to those receiving intensity modulated radiation therapy (IMRT). Tumor control also improved at the longest follow-up for proton therapy-treated patients (81% vs. 64%).
Researchers have uncovered 31 genes crucial to the development, growth, and spread of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer. The study found eight previously unlinked genes and six unknown to any cancer type, highlighting potential new therapeutic targets.
Researchers at Mayo Clinic discovered that the NPTX2 gene is heavily involved in promoting clear cell renal cell carcinoma, the most common form of kidney cancer. The study reveals that NPTX2 plays a key role in this cancer type, which is resistant to chemotherapy and has a low five-year overall survival rate.
A Mayo Clinic study found that body mass index (BMI) might be missing 25 percent of children who are overweight despite having a normal BMI. This omission raises serious long-term health concerns for these children.
A recent study from Mayo Clinic warns of the dangers of home oxygen therapy combined with facial hair, particularly around sparks. Researchers found that mustaches can act as kindling for nasal oxygen tubes, leading to severe burns.
An international team created a heart disease risk calculator for rheumatoid arthritis patients, identifying those at high risk more effectively than standard tools. The calculator incorporates disease characteristics into cardiovascular risk assessment, shedding light on how to better gauge heart health in inflammatory diseases.
Mayo Clinic researchers have identified a new form of cancer caused by a chromosomal chimera, characterized by a biphenotypic sinonasal sarcoma. The rare tumor typically begins in the nose and may require disfiguring surgery to treat.
Researchers at Mayo Clinic have developed an optical blood oxygen sensor attached to an endoscope that can identify pancreatic cancer with a sensitivity of 92% and specificity of 86%. The device measures changes in blood flow near the pancreas, which tumors alter to grow. Early detection is crucial as most pancreatic cancers are diagno...
Researchers at Mayo Clinic and Aarhus University have discovered a receptor system critical for correct wiring of the dopaminergic brain area during embryonic development. The study found that a cut in the SorCS2 receptor can induce cell death after peripheral nervous system damage, leading to hyperactivity and attention deficits in mice.
Researchers at Mayo Clinic have demonstrated a potential delivery vehicle for brain cancer chemotherapy drugs, enabling the transport of eight different molecules across the blood-brain barrier. The breakthrough method mimics a normal physiological process and could aid in evaluation of new drugs for brain cancer treatment.
A study by Mayo Clinic researchers found that the size of tumors before treatment is a strong predictor of response to immunotherapy drug MK-3475. The findings suggest that decreasing baseline tumor size through surgery or other means may be more effective in inducing long-lasting remissions.
Researchers used gene expression arrays to analyze biopsies from ICON7 patients and found that patients with proliferative and mesenchymal subtypes responded best to bevacizumab. This subtype analysis may help identify patients who will benefit from the treatment, potentially reducing unnecessary toxicity.
The ALTTO trial showed that adding lapatinib to trastuzumab and chemotherapy did not improve patient outcome, while increasing toxicity. Researchers suggest standard adjuvant treatment should remain trastuzumab with chemotherapy for early stage HER2-positive breast cancer.
A chemotherapy regimen after radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas by an average of 5.5 years compared to radiation alone. The study, RTOG 9802, also found better outcomes for patients with oligodendroglioma and females.
Mayo Clinic researchers have discovered an enzyme, Rac1b, that is tightly linked to the development of aggressive pancreatic cancer. The study provides key insights into the most aggressive form of the disease and offers a potential way to gauge outcome in individual patients.
A Mayo Clinic review of 47 studies found that complex, patient-centered interventions can reduce 30-day readmissions by almost 40%. These interventions include in-person visits to patients' homes after discharge to assess their living environment and needs.
A Mayo Clinic study finds that implementing a uniform method to care for lower-risk cardiac surgical patients reduces hospital time by 15% and lowers overall costs by 15%. The new model sets clear expectations for hospital care, improves patient experiences, and reduces variability in costs and outcomes.
A recent Mayo Clinic study found that nerve damage after hip surgery may be caused by inflammation, rather than mechanical factors. The study identified key signs for physicians to look out for, including delayed onset of neuropathy and severe pain.
Mayo Clinic researchers define a new subtype of Alzheimer's disease that produces different symptoms and affects the brain in unique ways. This subtype, called hippocampal sparing AD, may be misdiagnosed as other conditions, but could be treated with current medications.
A Mayo Clinic study found that ultrasound images of underarm lymph nodes are more accurate in overweight and obese breast cancer patients than in those with a normal body mass index. The research suggests that soft fatty tissue can be compressed during ultrasounds, leading to better specificity and accuracy for these patients.
A recent Mayo Clinic study discovered that individuals with mild cognitive impairment (MCI) tend to die at a higher rate than those without the condition. People with MCI experience an 80% increased risk of death over nearly six years.
A Mayo Clinic-led study found nine independent risk factors for acute respiratory distress syndrome in surgical patients, including sepsis and high-risk cardiac surgery. The findings may lead to better identification of high-risk patients before surgery and inform changes in care to prevent the condition.
Researchers found that rheumatoid arthritis patients have a 1 in 4 chance of developing chronic kidney disease over a 20-year period, compared to the general population's 1-in-5 risk. Patients should work to keep blood pressure under control and avoid medications damaging to the kidneys.
The Mayo Clinic uses frozen section analysis during breast cancer lumpectomies, sparing patients the need for repeat surgeries in 96% of cases. This technique significantly lowers the 30-day reoperation rate from 13.2% nationally to 3.6% at Mayo.
A new study by Mayo Clinic reveals that CT scans are effective in detecting uric acid crystals around joints, particularly in patients with multiple gout-like flares. Accurate diagnosis is crucial as gout patients require different medication than those with other forms of inflammatory arthritis.
Researchers at Mayo Clinic have discovered a specific genetic defect in the SCN5A gene that causes disruption in bowel function, leading to irritable bowel syndrome. This breakthrough finding has given researchers hope of developing disease-modifying agents to treat IBS.
Cologuard detects precancer and cancer with high sensitivity rates, surpassing existing non-invasive tests, offering a user-friendly approach to expand screening effectiveness and curb colorectal cancer rates. The test's accuracy has transformed how we think about colorectal cancer screening.
A large waist circumference is associated with increased mortality risk, even among individuals with a healthy body mass index (BMI). Men and women with larger waists are more likely to die younger and die from illnesses such as heart disease and cancer. Researchers recommend considering both BMI and waist circumference in risk assessm...
A new approach to breast reconstruction surgery, known as an enhanced recovery pathway, has been shown to reduce opioid painkiller use in patients by 50% and decrease hospital stays by a day on average. The method includes preoperative analgesics, nonsteroidal anti-inflammatories, and resuming food and walking soon after surgery.
A study by Mayo Clinic researchers found that patients who had troublesome teeth extracted before heart surgery were at a higher risk of poor outcomes, including death. The study suggested that physicians should evaluate each patient individually to weigh the benefits and risks of tooth extraction before cardiac surgery.
A new study by Mayo Clinic reveals that African-American individuals develop twice the antibody response to the rubella vaccine compared to Caucasians. This finding may enable the creation of vaccines tailored to specific ethnic groups or individuals, offering a more effective approach to immunization.
A Mayo Clinic study found that blacks are twice as likely to develop multiple myeloma because they are more likely to have monoclonal gammopathy of undetermined significance (MGUS). The study also showed that the type of MGUS in blacks is associated with a higher risk of progression to full-blown multiple myeloma.
Researchers discovered a protein responsible for gas exchanges in zebrafish gills, which may mimic human kidney function. NHE3 protein controls sodium and hydrogen ions, aiding in energy-saving balance and waste removal.
Researchers discovered that SPOP protein selectively destroys androgen receptor, a master regulator of prostate cancer cell growth. This finding sheds light on a new mechanism by which prostate cancer develops.
A study found that patients undergoing PCI have a higher risk of dying from non-cardiac diseases than heart disease, with only 37% of deaths being cardiac-related. The researchers attribute this to improved cardiac therapies, such as medication and catheterization laboratory technologies.
A Mayo Clinic study found a significant rise in skin cancer among middle-aged adults, with incidence increasing nearly eightfold between 1970 and 2009. Women between 40 and 50 showed the highest rates of increase, while men were more likely to have deeper lesions.
The new cholesterol guidelines suggest that caregivers prescribe statins to healthy patients if their 10-year cardiovascular risk is 7.5 percent or higher. A decision-making tool can help patients and clinicians weigh the benefits and harms of treatment, making a personalized choice based on individual values and context.
A Mayo Clinic study found that using a standardized medical management protocol and surgery can improve life expectancy for stroke patients. The treatment, which involves decompressing brain swelling, reduces pressure in the head and risk of death by about 50 percent.
Glaucoma blindness risk has dropped by half in the last generation, according to Mayo Clinic research. The study found a significant decrease in the probability of going blind in at least one eye due to glaucoma.
Researchers have found that trastuzumab can improve outcomes for bladder cancer patients with HER2 amplification, a known driver of aggressive tumors. The study identified 15% of MPUC patients had HER2 amplification, leading to faster growth and higher recurrence rates.
A study published in Mayo Clinic Proceedings reveals that most guidelines are based on lower-quality evidence and fail to disclose authors' conflicts of interest. The study highlights the need for more concise and transparent guideline development processes.
A Mayo Clinic study found that nearly all patients with intact rotator cuffs experience improved function and pain relief after shoulder replacement surgery. The procedure improves range of motion and reduces pain in nearly all cases, especially for those with rheumatoid arthritis.
A recent study at Mayo Clinic suggests that certain types of fractures in children may be linked to lower bone strength and a higher risk of osteoporotic fractures later in life. The study found that children with mild-trauma distal forearm fractures had weaker bones compared to those with moderate trauma or no fractures.
Combining varenicline and bupropion for smoking cessation showed increased quit rates in heavier and more dependent smokers. However, the effects were similar in lighter smokers using varenicline alone.
Mayo Clinic researcher Abba Zubair is sending human stem cells into space to see if they grow more rapidly than on Earth. The experiment aims to expand the population of stem cells that can induce regeneration of neurons and blood vessels in patients who have suffered a hemorrhagic stroke.
A Mayo Clinic-led study found that pain drugs used in prostate gland removal may be linked to cancer outcomes, as they can suppress the immune system's ability to fight cancer cells. The research suggests that a specific technique using opioids may reduce the risk of cancer recurrence and mortality.