Researchers at McMaster University have established a strong association between inflammatory bowel disease (IBD) and celiac disease. The study found a nine-fold increased risk of IBD in patients with a previous diagnosis of celiac disease, highlighting the importance of proper screening and treatment for both conditions.
A new study reveals that climate change is causing a significant loss of water from peatlands, which can accelerate global warming by releasing stored carbon into the atmosphere. This can lead to more intense fires and worsen the boreal landscape.
Researchers found that consuming potato protein isolate increased the rate at which muscles made new protein in young women, highlighting its potential as a plant-based alternative for supporting muscle maintenance. The study suggests that current dietary recommendations may be inadequate to support muscle growth and development.
A McMaster University study found that half of online vaccination information on chiropractors' websites was removed after media coverage. The removal was associated with a large increase in Canadian media attention on anti-vaccination statements by some chiropractors.
The human genome's complexity hinders personalized medicine by having an immense ability to change and cope with issues, context matters in our genome. Researchers conclude that precision medicine is crucial but must consider the full genomic blueprint including 'unnecessary' elements.
A new randomized control trial will examine the effectiveness of Goal Management Training, a cognitive remediation strategy, in improving functional outcomes among first responders with PTSD. The study aims to understand changes in brain structure and function using magnetic resonance imaging.
Researchers aim to understand COVID-19 infection rates and identify individuals with different immune responses. They plan to collect blood samples from residents and healthcare workers to analyze the impact of SARS-CoV-2 on the human body.
A systematic review of medical masks vs. N95 respirators found that the former did not increase viral respiratory infection or clinical illness; however, N95 respirators are best for aerosol-generating procedures. The study suggests preserving N95 respirators for high-risk care and using medical masks for routine treatment.
The Surviving Sepsis Campaign COVID-19 panel has released comprehensive guidelines for intensive care unit (ICU) patients with COVID-19, including infection control, laboratory diagnosis, and ventilator support. The guidelines were developed in just three weeks by a team of 36 experts from around the world.
An international team of experts has released 54 recommendations for caring for ICU patients with COVID-19, including guidelines on infection control, ventilation support, and therapy. The guidelines were developed in just three weeks and provide critical guidance for frontline clinicians, allied health professionals, and policy makers.
A McMaster University expert urges the establishment of an independent international safeguarding agency for sports to handle athlete disclosures, investigate and process allegations. An international database of offenders is also needed to prevent perpetrator migration.
Researchers at McMaster University have discovered a non-psychoactive cannabinoid called CBG that shows promising antibacterial activity against drug-resistant MRSA. The study found that CBG prevents the ability of bacteria to form biofilms and destroys preformed biofilms, targeting the cell membrane of the bacteria.
Two out of three young mothers have at least one mental health problem, with almost 40% having multiple issues including depression and anxiety. The study's findings can be used to develop better screening processes for this vulnerable population.
A Canadian survey of 2,300 people found that 30% of Canadians use condoms during penile-vaginal intercourse, with higher rates among young adults, men from visible minority groups, and those with education on condom usage. The study highlights the importance of condom education in reducing STIs and unintended pregnancies.
A new group of antibiotics, corbomycin and complestatin, have been discovered with a unique approach to killing bacteria by blocking the function of the bacterial cell wall. The researchers demonstrated its effectiveness in mice against drug-resistant Staphylococcus aureus infections.
Researchers have developed a novel technology that enables the communication between light beams through solid matter, paving the way for a new form of computing. The innovative material, resembling raspberry Jell-O, incorporates light-responsive molecules that can contain and transmit information between filaments of laser light.
A new study from McMaster University and Université de Montréal found that the first type of influenza virus exposed to in early childhood determines lifelong immunity. This phenomenon, known as antigenic imprinting, has important implications for pandemic and epidemic planning.
Children who spend time in a neonatal intensive care unit (NICU) at birth have a higher risk of mental health issues later in childhood and adolescence. NICU graduates are nearly twice as likely to develop any mental disorder or multiple mental illnesses, according to the study.
A large multinational study found no harm from consuming eggs, with moderate intake (one egg per day) not increasing the risk of cardiovascular disease or mortality. The study analyzed data from 146,011 individuals across 21 countries and found no association between egg consumption and blood cholesterol levels.
Researchers at McMaster University discovered that scurvy, a disease caused by vitamin C deficiency, still exists in Canada. The study found 52 patients with low Vitamin C levels, including 13 with diagnosed scurvy and 39 who tested positive but lacked symptoms.
Researchers have designed modified red blood cells that can circulate for several weeks and target specific infections or diseases like cancer and Alzheimer's. These 'super-human' cells use a sticky surface to attach to bacteria and release antibiotics exactly where needed.
A team of McMaster University chemists has discovered a method to efficiently break down and dissolve tire rubber, paving the way for more effective recycling. The process addresses the massive environmental burden posed by 3 billion tires worldwide, which can leach contaminants into ecosystems.
A study by McMaster University researchers found that levels of NT-proBNP, a common cardiac blood test, can predict cardiac and vascular complications after non-cardiac surgery. The test may help doctors identify patients at risk and inform treatment decisions.
A new study has found that Canadian First Nations communities with higher socio-economic advantages, educational opportunities, and social support have lower cardiac risk factors. In contrast, communities with difficulty accessing healthcare or affordable prescription medicines have a greater burden of cardiac risk factors.
Researchers at McMaster University developed a self-cleaning surface that can repel all forms of bacteria, preventing the transfer of antibiotic-resistant superbugs in medical settings. The treated material is also suitable for food packaging to prevent bacterial contamination, such as E. coli and Salmonella.
Researchers at McMaster University found that metformin induces the expression and secretion of protein GDF15, which suppresses appetite and may contribute to weight loss. The study opens new avenues for research into the potential effects of metformin on aging and diseases.
A multi-centre trial led by McMaster researchers found that accelerated partial breast irradiation (APBI) is as effective as whole breast radiation in reducing breast cancer recurrence, with similar recurrence rates after one week of treatment. However, APBI was associated with higher late toxic effects and worse cosmetic outcomes.
Researchers at McMaster University created a new coating material to prevent clotting and infection in synthetic vascular grafts. The smart coatings selectively attract targeted cells, promoting faster, smoother healing. The coatings have already been approved for use in humans.
A new approach to interpreting D-dimer blood tests can help rule out pulmonary embolism and reduce the need for CT scans, freeing up resources and reducing radiation exposure. The study found that a higher-than-usual D-dimer level can be considered a negative result in patients with low probability of having a pulmonary embolism.
Researchers at McMaster University have discovered a potent new antimicrobial that works against the toughest infectious disease strains, including MRSA. The compound, MAC-545496, cripples MRSA's ability to cause infection by diminishing its tolerance to the immune system and blocking its resistance to antibiotics.
A McMaster University study found that virtual and mixed reality inferior to traditional physical models for anatomy learning. The research showed a 70% increase in accuracy with traditional physical models compared to digital media.
Research at McMaster University found that cannabis use didn't reduce illicit opioid use during treatment and failed to retain people in treatment. The study involved over 3,600 participants and provided limited insight into the potential benefits of cannabis as an 'exit drug' for opioid use disorder.
A team of biologists found at least seven different systems regulating sex determination across closely related species. Genetic analysis revealed three underlying mechanisms driving sexual differentiation in frogs, including the empowerment of a gene that becomes potent for female-specific sex determination.
A study published in Annals of Internal Medicine found a program that fulfils end-of-life wishes can ease bereavement by encouraging conversations about the patient's identity. The project, which costs around $5 per wish, has been successful at several hospital intensive care unit sites.
Researchers found that first permanent molars carry life-long records of health information from the womb, storing vital data on Vitamin D intake and its impact on health. These 'living fossils' can provide clues connecting maternal health to a child's eventual fate.
Researchers have identified a new bacteria-killing toxin that depletes cells of ATP, leading to bacterial death. This discovery holds potential for developing alternatives to antibiotics and addressing antimicrobial resistance.
Researchers at McMaster University have identified chemical signatures detectable in blood and urine that can accurately measure dietary intake. The study validates a panel of metabolites in urine and plasma that correlate with consumption of fruits, vegetables, protein, and fiber.
A McMaster University study found that teens who spend more time on TV and electronic devices consume more sugared and caffeinated drinks. The research suggests that counseling or health promotion could help address this issue, which is linked to obesity, diabetes, and other health problems.
An international research team has found evidence of human activity on the island of Naxos at least 200,000 years ago, forcing a reevaluation of human movement in the region. The discovery pushes back the known settlement timeline by tens of thousands of years and suggests that early humans were capable of adapting to new environments.
A McMaster University study found that statin drugs cause muscle pain by releasing glutamate, a potent activator of pain receptors. Administering antioxidants like Vitamin E can help reduce glutamate release.
A major Canadian-led study has found that most adults can continue to eat red and processed meat without significant impacts on heart disease, diabetes, or cancer. The researchers concluded that a small reduction in risk was associated with reducing meat consumption by three servings per week.
A simple cardiac risk score is associated with MRI-detected pre-clinical cerebrovascular disease, including carotid artery plaque and silent strokes. Early detection and treatment of cardiovascular risk factors can prevent cerebrovascular disease from developing.
A large clinical study of 1,495 patients in 10 countries found that those who had a total hip arthroplasty reported better function but also higher incidence of serious complications. The study suggests the advantages of total hip replacement may not be compelling.
A team of scientists has solved the mystery of 'Fraser's Clawed Frog', an unusual species found in West Africa. The study, published in PLOS ONE, reveals that the frog inhabits hot and arid regions of northern Cameroon and Ghana, contradicting previous assumptions about its geographic origin.
A new study by McMaster University researchers reveals that over 1,125,000 men globally have hemophilia, with 418,000 having severe forms of the disease. The study found a significant life expectancy disadvantage for those with hemophilia, particularly in lower-income countries.
A large international study found that cardiovascular disease (CVD) remains the leading cause of death worldwide, but its share has declined in high-income countries where cancer deaths have become more frequent. CVD risk factors are highest in rich countries, yet mortality rates are lower, suggesting other factors may be at play.
A large international study found that more than 70% of cardiovascular disease and deaths globally may be attributed to a small number of modifiable risk factors. The 14 identified risk factors include hypertension, low education, poor diet, air pollution, and indoor air pollution, which have varying impacts on health across countries ...
A community-based intervention involving non-physician health workers and personal supporters significantly reduced cardiovascular risk in patients with hypertension. The study found a 40% reduction in cardiovascular risk, improved blood pressure control, and enhancements in medication adherence, physical activity, and diet.
A new study published in the New England Journal of Medicine shows that opening all clogged arteries after a serious heart attack leads to a 26% reduction in patient risk of dying or having a recurrent heart attack. This approach also shows no major downside to additional procedures.
A meta-analysis of 40 studies reveals that individuals with psychiatric disorders such as major depressive disorder, bipolar disorder, and borderline personality disorder exhibit heightened impulsivity. The study suggests a continuum between impulsive and self-controlled decision-making across different disorders.