Researchers created a synthetic model of E. coli's outer membrane, providing unprecedented access to its structure and dynamics. The model was used to test how antibiotic molecules can cross the critical barrier, which is highly impermeable to incoming molecules.
A Newcastle University study found that stressed baby starlings grow into fat and greedy adults, changing their eating behavior as a result. The research showed that chicks that faced greater competition for food as juveniles tend to overeat when presented with freely available food.
Researchers at Newcastle University have created a synthetic model of the bacterial outer membrane, providing unprecedented access to its structure and dynamics. The model allows for the testing of antibiotic molecules and has the potential to overcome resistance in Gram-negative bacteria, such as E. coli.
A new study published in Marine and Petroleum Geology has established a national baseline for earthquakes caused by human activity in the UK. Since 1999, an average of at least three onshore earthquakes per year with local magnitude greater than or equal to 1.5 have been linked to anthropogenic activities.
The company, Newcells Biotech Ltd, will use pioneering technology to create iPSCs for pharmaceutical, biotechnology, and academic customers, offering benefits in testing treatments on cells with specific genetic make-ups.
Scientists have identified a new family of copper storage proteins called Csp that are present in diverse bacteria, raising questions about how bacteria use copper ions. This discovery may help develop biotechnological applications to exploit methane and protect the environment from its potent greenhouse gas effects.
Researchers have documented the full spectrum of UV radiation-induced DNA damage in human skin cells, allowing manufacturers to develop targeted sunscreen products. The study's findings reveal that prolonged sun exposure leads to an accumulation of damaging free radicals, causing skin aging and potentially initiating skin cancers.
Researchers have discovered a new insight into glacier behavior, revealing the rapid movement of glaciers backward and downward during calving events. This phenomenon helps scientists measure glacier calving remotely and improve sea-level rise predictions.
A new study suggests that personalized nutrition plans based on an individual's genotype could significantly reduce the risk of obesity, heart disease, and Type II diabetes. However, concerns over personal data protection are hindering widespread adoption of nutrigenomics, a relatively new branch of nutrition.
Researchers have discovered that the upward motion of Antarctica's crust is occurring at a rate of 15mm per year, much faster than previously thought. The land is rising due to the melting of glaciers and the subsequent reduction in weight on the Earth's crust.
Biologists at Newcastle University use 'confusion effect' to temporarily disorient whiteflies, reducing their ability to feed on tomato plants. The study suggests a potential new method for sustainable pest control, using harmless plant volatiles to give plants time to defend themselves.
Researchers at Newcastle University are investigating Google Glass as an assistive aid to help people with Parkinson's retain their independence. The technology is voice-operated and linked to the internet, providing discreet prompts to support key behaviours typical of Parkinson's.
Researchers found high levels of antibiotic-resistant genes in river water during peak pilgrimage season, linked to overcrowding and poor waste management. The study emphasizes the importance of protecting sacred sites while preventing the spread of 'superbugs', highlighting the need for improved sanitation and waste treatment.
Researchers have successfully implemented a 'natural' flood management scheme in Belford Burn, Northumberland, reducing the risk of flooding and pollution. The scheme, costing £200,000, uses soft engineering solutions to restrict water flow and increase soil infiltration.
Researchers have identified a potent antioxidant called Tiron that provides complete protection against UVA radiation and oxidative stress, offering potential benefits for anti-aging and sun-damaged skin. The study suggests that Tiron could be used to develop new skincare products or supplements, but further testing is needed.
Researchers found that girls' brains undergo a selective process called preferential detachment, preserving long-distance connections that integrate information. This process may explain why brain function improves during maturation in females.
Researchers at Newcastle University have identified a gene mutation that causes mice to exhibit excessive alcohol consumption. The study found that mice with the mutation preferred drinking alcohol over water and would work to obtain it, even becoming intoxicated.
Researchers at Newcastle University developed a technology that tracks dog behavior to detect potential health issues in owners. The system uses movement sensors and machine learning algorithms to identify changes in canine behavior that may indicate declining health or boredom.
Researchers found that some whale species darken their skin with UV exposure, accumulating DNA damage, similar to humans. Fin whales, however, were resistant to sun damage, offering insights into evolutionary adaptations to counteract UV radiation.
A new map ranks 30 UK cities on their preparedness for climate change, with huge variation in readiness levels across the country. London and Leicester scored highly, but many cities lack effective strategies and monitoring systems to mitigate flooding and droughts.
Research shows that selective grazing by slugs can prevent key grassland species from taking hold and reduce overall plant diversity. The team found that some of the most ecologically important species, such as red clover, are particularly tasty to slugs, which may hinder restoration efforts.
A global cooling event, similar to recent global warming, occurred 116 million years ago, causing a marine ecosystem crisis and reducing atmospheric CO2 levels. This study highlights the link between global climate and internal earth processes, demonstrating that large-scale changes can have severe consequences for marine life.
A new formula predicts when brain haemorrhage patients need surgery for the best outcome, helping ensure the right treatment at the right time. This study aims to improve patient survival rates and independence.
A new skin test called Skimune has been developed by Newcastle University to predict adverse reactions to new drugs and cosmetics. The test uses real human skin and immune cells to identify potential risks, providing a faster and more accurate alternative to animal testing.
Researchers at Newcastle University have discovered a molecular mechanism that enhances attention and reduces cognitive noise in the brain. By manipulating glutamate coupling to NMDA receptors, they improved perceptual abilities and increased the fidelity of neural responses.
The 'Repentir' smart phone and iPad app uses computer vision algorithms to reveal the multiple hidden stages of a painting. Users can explore the artist's creative process by rubbing away layers or scrolling through sequence images.
Researchers discovered a molecular switch regulating biofilm formation, which could help identify new antibiotics and prevent biofilms from forming. The study sheds light on how bacteria shield themselves in a slimy protective layer to evade attacks.
A study from Newcastle University found that vitamin D supplements improve muscle efficiency in patients with severe deficiency, leading to reduced fatigue and improved mitochondrial oxidative function. The research suggests a link between vitamin D and mitochondrial function, potentially offering a new way to boost energy levels.
Scientists have shown that caffeine enhances a honeybee's memory of floral traits, allowing them to remember flowers better. This discovery could lead to improved pollination and plant recruitment.
Researchers isolated an enzyme called NucB from the marine bacterium Bacillus licheniformis, which can break down biofilms in sinusitis. The enzyme cleared over half of biofilm organisms tested, offering a potential solution to chronic sinusitis.
Experts at Newcastle University have discovered a way to convert CO2 into harmless calcium or magnesium carbonate using Nickel nanoparticles. This process has the potential to significantly reduce CO2 emissions from industries such as power stations and chemical processing plants.
The EU has announced €38 million funding for research into rare diseases, aiming to develop new diagnostics and treatments through global data sharing. Advances in DNA sequencing have brought personalized treatments closer, but scientists now need to collate data to identify genetic causes of diseases.
A team of European experts, led by Newcastle University, has designed blast-proof technologies to reduce debris and protect passengers in the event of a bomb attack. The new technology is being incorporated into European and national standards, aiming to save lives and prevent terrorist attacks on railways.
Researchers at Newcastle University used X-ray Photoelectron Spectroscopy (XPS) to analyze the build-up of hydrocarbons on replica kilograms, finding that a suntan could help remove contamination and bring prototype weights back to their ideal mass. The study highlights the significance of maintaining precise measurements in internatio...
A new study using Gravity Recovery and Climate Experiment (GRACE) satellite data has re-calibrated the scales to more accurately calculate ice mass loss. The research found that Antarctica overall is contributing less to sea-level rise than previously thought, with West Antarctica losing mass at an accelerated rate.
A recent study published in the Journal of Neuroscience found that the brain's amygdala and auditory cortex interact when processing negative emotions triggered by unpleasant sounds. The study used fMRI to examine how brains responded to a range of sounds, from knife-on-bottle to soothing water flowing.
Research by Newcastle University found that uncomfortable weather leads to longer phone calls with close friends and family, while fewer calls are made to wider networks. The study analyzed data from over 1.3 million mobile phone users in Portugal, revealing the influence of weather on human behavior.
The Digits sensor allows users to control devices remotely using hand gestures, eliminating the need for external hardware. Researchers have made significant breakthroughs in understanding human hand movements and developing a system that can accurately track and interpret finger joints, wrist orientation, and other key points.
The low-cost scanner can be manufactured for £30-40 and produces an output power that is 10-100 times lower than conventional hospital ultrasounds. It aims to provide basic antenatal imaging to women in developing countries where such tests are not available, potentially saving hundreds of thousands of lives.
Researchers at Newcastle University have found that brain cells follow the same molecular pathway as senescent fibroblasts, leading to cell damage and age-related diseases. This discovery opens new possibilities for understanding and treating conditions like dementia and motor neuron disease.
Research reveals widespread skin cancer in wild coral trout populations, caused by UV radiation, affecting three species on the Great Barrier Reef. The study's findings highlight the urgent need for continued conservation and management of reefs and their inhabitants.
Researchers at Newcastle University have identified a new type of white blood cell that activates a killing immune response to external sources, providing a potential target for vaccines. The discovery could lead to the development of targeted immunotherapies against cancer and infections such as Hepatitis B.
Researchers found that around 26% of people aged 87-89 had previously undiagnosed heart problems. These conditions can lead to breathlessness and heart failure, but are treatable with established drugs like beta-blockers and ACE inhibitors.
Researchers at Newcastle University used biomechanical motion capture to analyze pigs' gait and identify those at risk of becoming lame. The study aims to develop a farmer-friendly system to predict leg problems and reduce lameness, improving health and welfare on UK farms.
Research finds green rust played a crucial role in oxygenating the Earth's atmosphere, scavenging heavy metals like nickel from water. The mineral's high reactivity makes it promising for cleaning up polluted sites and removing toxic metals.
Children aged 8-10 years spent an average of just 4% of their day engaging in moderate to vigorous physical activity, falling short of the daily recommended amount. This early disparity highlights the need for interventions to encourage primary school children to become more physically active.
Researchers at Newcastle University have identified a unique brain wave pattern, called glissando, that can predict epileptic seizures. The study found that this pattern is highly indicative of human epilepsy and cannot be easily reproduced in non-epileptic brain tissue.
New research reveals that simulating weather and water conditions before a race can predict a yacht's behavior with accuracy, giving sailors a competitive advantage. The study uses virtual simulation to model resistance on the hull, comparing results with physical tests.
Researchers at Newcastle University are using a mobile laboratory car called DriveLAB to develop new technologies to support older drivers. The team is investigating in-vehicle systems that can help keep people driving safely into their 70s, 80s, and beyond.
A new study reveals that the Earth's early atmosphere periodically transitioned between a hydrocarbon-rich state and a haze-free environment due to microbial activity. This 'see-sawing' phenomenon had a profound impact on the climate system, with evidence suggesting a significant role in regulating atmospheric oxygen levels.