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Okinawa Institute of Science and Technology (OIST) Graduate University


Eco-friendly treatment saves squid eggs from newfound parasite

Researchers at Okinawa Institute of Science and Technology have successfully treated a newly discovered parasitic copepod species that was killing squid eggs. The eco-friendly treatment uses peracetic acid to kill the parasites in under two minutes, with zero effect on squids or their generations.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalScientific Reports·TypeExperimental study·DateJul 22, 2024

Simplicity versus adaptability: Understanding the balance between habitual and goal-directed behaviors

A new study on learning has provided insights into the balance between habitual and goal-directed behaviors, with implications for AI development. The research suggests that a balance between these two types of behavior is necessary for efficient and adaptable decision-making in AI systems.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeComputational simulation/modeling·DateJun 16, 2024

How does oxygen depletion disrupt memory formation in the brain?

Scientists at Okinawa Institute of Science and Technology identify a positive glutamate-NO-glutamate feedback loop that blocks long-term potentiation and impairs learning and memory. The study suggests that this loop may explain memory loss in stroke patients and potentially offer a solution for treatment.

Taking care of caregivers of children with ADHD

A new 13-week group-based parent training program, Well Parent Japan (WPJ), has been shown to be effective in reducing parenting-specific stress, improving parenting efficacy, and reducing family strain for Japanese mothers of children with ADHD. The program provides social support and encourages shared learning amongst participants.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalJournal of Child Psychology and Psychiatry·TypeRandomized controlled/clinical trial·DateJun 4, 2024

Lighting up the brain: What happens when our ‘serotonin center’ is triggered?

Researchers at OIST used a novel technique to study how activating the brain's serotonin center affects awake animals. They found that serotonin from the dorsal raphe nucleus (DRN) activates brain areas influencing behavior and motivation, including the cerebral cortex and basal ganglia.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeExperimental study·DateMay 31, 2024

Surprising properties of elastic turbulence discovered

Elastic turbulence, a chaotic fluid motion in non-Newtonian fluids, exhibits universal power-law decay of energy and intermittent behavior. This study reveals its unexpected similarity to classical Newtonian turbulence, paving the way for developing a complete mathematical theory and predicting flow patterns.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeComputational simulation/modeling·DateMay 27, 2024

Scientists solve chemical mystery at the interface of biology and technology

Researchers discovered a two-step process behind the lagging behavior of organic electrochemical transistors (OECTs), which can be customized to improve data processing speed. The study's findings may help design better materials for next-generation applications in biosensing and brain-inspired computation.

Synthetic droplets cause a stir in the primordial soup

Scientists from OIST created synthetic droplets to mimic biological processes, finding that pH gradients facilitate Marangoni effect and enabling droplets to detect and migrate towards each other. This study sheds light on the movement of simplest forms of life in primordial soup billions of years ago.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalJournal of the American Chemical Society·TypeExperimental study·DateApr 25, 2024

Unveiling the mysteries of cell division in embryos with timelapse photography

Researchers used medaka fish, CRISPR and new imaging techniques to study embryonic mitosis. They discovered unique spindles assemble in early embryos and found Ran-GTP plays a decisive role in spindle formation, which diminishes later in development. The study paves the way for further exploration of embryonic mitosis.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeImaging analysis·DateApr 24, 2024

Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment

Researchers discovered a protein complex that eliminates potentially harmful cells over time by measuring the duration of mitosis. The Mitotic Stopwatch Complex starts forming after prolonged mitosis and triggers cell arrest or death, providing new insights into cancer development.

Innovative magnetic levitation: New material offers potential for unlocking gravity-free technology

Researchers at OIST create a floating platform using graphite and magnets that operates without external power, opening potential for ultra-sensitive sensors and precision measurements. The new material, derived from graphite, overcomes energy loss challenges, allowing the platform to achieve 'frictionless' motion.

Standardizing solar power analysis: Researchers seek solutions for variability in renewable energy generation

Scientists created a method to study variations in power output from solar PV plants over time, accounting for distinct power fluctuations across different geographical areas. The grid integration challenge arises when including variable renewable energy sources like wind and solar into the power grid.

“Frozen behaviors” in amber fossils – how to reconstruct mating behavior of long-extinct termites

Researchers from OIST used X-ray micro-CT to study a 38 million-year-old termite pair trapped in amber, revealing a male and female in tandem running behavior. The discovery provides new insights into the fidelity of behavior fossilization in amber.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMar 6, 2024

Damage to cell membranes causes cell aging

A recent study published in Nature Aging suggests that mechanical damage to the cell membrane can induce cellular senescence, a state characterized by cell cycle arrest and tissue dysfunction. This mechanism involves calcium ion influx and the tumor suppressor gene p53, offering new insights into the aging process.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Aging·TypeExperimental study·DateFeb 22, 2024

Clown anemonefish seem to be counting bars and laying down the law

Researchers observed that clown anemonefish colonies display the most aggressive behavior towards fish with three bars like themselves. The fish also recognize different anemonefish species based on the number of vertical white bars, leading to strict social hierarchies and upholding dominance.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalJournal of Experimental Biology·TypeExperimental study·DateFeb 1, 2024

Acoustic monitoring shows surprising resilience of subtropical forests to extreme weather – but climate change looms

Researchers analyzed 13,000 hours of audio data from Okinawan forests before, during, and after typhoons, finding that ecosystems responded differently than expected. The study suggests that developed sites were more resilient to extreme weather than anticipated, but climate change may push these ecosystems to their limits.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalGlobal Change Biology·TypeData/statistical analysis·DateDec 7, 2023

Okinawa’s ants change their seasonal rhythms amid land-cover changes

Ant communities in Okinawa Island show reduced seasonal behavior in areas with more human development. Researchers found that ant populations in developed sites are less predictable and have diminished seasonality compared to forested areas. The study highlights the impact of human activities on insect populations and ecosystem services.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalProceedings of the Royal Society B Biological Sciences·DateOct 27, 2023

Scientists synthesize new organometallic “sandwich” compound capable of holding more electrons

Scientists at OIST have synthesized a new metallocene compound capable of holding up to 21 electrons, surpassing the traditional 18-electron limit. This breakthrough has significant potential for applications in medicine, catalysis, and energy, and could lead to novel materials with improved stability and performance.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeExperimental study·DateSep 5, 2023

Researchers solve structure of immune-evading HIV protein complex

Okinawa Institute of Science and Technology researchers determined the atomic structure of the APOBEC3G-Vif complex using cryo-electron microscopy. This discovery may help develop antiviral therapies by targeting the interaction between HIV-1's Vif protein and the human innate immune system.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeExperimental study·DateJul 14, 2023

The incredible journey of clownfish larvae: Mini athletes, maximum performance

Researchers investigated the role of thyroid hormones in coordinating the metamorphosis of clownfish, discovering a strong interaction between metabolic processes and hormone regulation. Thyroid hormones play a critical role in timing the transformation and supporting energy demands during the journey.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalCell Reports·TypeExperimental study·DateJul 11, 2023

NTT and OIST make the first simultaneous atmospheric and marine observations directly beneath a violent, Category 5 typhoon in the North-West Pacific

Researchers from NTT and OIST successfully conducted the world's first simultaneous marine and atmospheric measurements directly beneath a violent, Category 5 typhoon in the North-West Pacific. The study aimed to improve typhoon prediction accuracy by understanding the mechanisms of interaction between the atmosphere and ocean using ob...

Inhaled ethanol may treat respiratory infections and stop pandemics

A new study found that inhaling low concentrations of ethanol vapor can inactivate the influenza A virus in mice without harmful side effects. The researchers believe this method could also treat similar viruses like Covid-19 and potentially stop pandemics. However, further evaluation is needed to ensure its efficacy and safety on humans.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalThe Journal of Infectious Diseases·TypeExperimental study·DateApr 26, 2023

Gut bacteria could be behind weaker immune responses to COVID-19 vaccine

A study published in Communications Biology suggests that gut bacteria's digestion of fucose sugar may be behind weaker immune responses to the COVID-19 mRNA vaccine. Individuals with lower T-cell responses had higher expression of genes FOS and ATF3, which are part of a larger group controlling T-cell survival and activity.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalCommunications Biology·TypeObservational study·DateApr 20, 2023

New RNA-based toolkit to regulate gene activity could advance regenerative medicine, gene therapy and biotechnology

Scientists developed a new RNA-based toolkit that can regulate gene expression, potentially improving regenerative medicine, gene therapy, and biotechnology. The technology uses small molecules to control the activity of synthetic RNA, allowing for precise control over gene expression.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalJournal of the American Chemical Society·TypeExperimental study·DateMar 30, 2023

Detecting coral biodiversity in seawater samples

Researchers have developed a method to measure coral biodiversity by extracting environmental DNA from seawater samples, allowing for accurate detection of coral species without direct observation. The technique has been confirmed to work with over 91% accuracy and may indicate presence of corals difficult to detect by human eyes.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalProceedings of the Royal Society B Biological Sciences·TypeExperimental study·DateMar 28, 2023

In hot water: Ocean warming impacts growth, metabolic rate and gene activity of newly hatched clownfish

A new study finds that ocean warming can impact the growth, metabolic rate, and gene activity of newly hatched clownfish larvae. The researchers found that warmer temperatures led to faster growth rates, higher metabolic rates, and changes in gene expression.

New insights into chordate body plan development answer long-standing questions on evolution

A recent study in Developmental Biology reveals the evolution of the chordate body plan from an echinoderm common ancestor. The research identifies key gene expression patterns and transcription factors that led to the development of the chordate nervous system, lateral mesoderm, and Spemann's organizer.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalDevelopmental Biology·TypeExperimental study·DateFeb 23, 2023

New pumping strategy could slash energy costs of fluid transport by 22%

A new pumping strategy has been developed to slash energy costs of fluid transport by up to 22%. By switching pumps on and off, turbulent flows can be reduced, resulting in more efficient fluid transport. This approach could bring significant economic and environmental benefits, particularly for the transition to green energy.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalScientific Reports·TypeComputational simulation/modeling·DateFeb 17, 2023

Mining at key hydrothermal vents could endanger species at distant sites

Researchers warn that deep-sea mining near hydrothermal vents in the Okinawa Trough could harm species hundreds of kilometers away due to interconnected ecosystems. Key vents should be protected for conservation, with some vent sites identified as crucial hubs for maintaining connectivity.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalEcology and Evolution·TypeData/statistical analysis·DateFeb 15, 2023

Testing their mettle: How bacteria in deep-sea vents deal with toxic metal environments

A new study identifies how bacteria in deep-sea hydrothermal vents survive and thrive in the presence of toxic metals like copper and cadmium. Bacteria use transporter proteins to pump out these metals, but also employ more complex strategies, such as flagella formation and granule growth, to detoxify cadmium.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalEnvironmental Microbiology·TypeExperimental study·DateJan 21, 2023

Pulses driven by artificial intelligence tame quantum systems

Researchers from Okinawa Institute of Science and Technology (OIST) have developed a machine learning-based method to discover non-intuitive pulse sequences that can cool mechanical objects to ultracold temperatures faster than traditional methods. This breakthrough showcases the utility of artificial intelligence in quantum technologies.