A massive global genetic study has identified over 500 new gene regions influencing blood pressure, more than tripling the known number. The study now explains almost a third of estimated heritability for blood pressure.
Researchers have identified key genetic changes that occur during colorectal cancer development, including 'chromosomal catastrophes' that lead to tumour growth and diversity
A new study found that goats can differentiate between positive and negative human facial expressions and prefer to interact with the former. The researchers observed that goats spent more time approaching images of happy faces than angry ones, suggesting a preference for positive emotions.
Scientists have unraveled how changes in nutrition determine the development of honeybees into queens or workers. Epigenetic patterns, including histones, play a crucial role in controlling gene expression and developmental outcomes.
Researchers at Queen Mary University of London and University of Cambridge developed auxetic materials with smooth curves, enabling repeated deformations without damage. These materials can be used in energy-efficient gripping tools, re-configurable shape-on-demand materials, and lattices with unique thermal expansion behaviour.
A clinical trial using stem cell transplants aims to grow a new immune system for people with untreated Crohn's disease. This innovative approach may help reduce gut inflammation and improve quality of life for patients suffering from the condition.
A new study found that Cannabidiol (CBD) significantly improved the survival rate of mice with pancreatic cancer when used alongside chemotherapy. The treatment resulted in nearly tripled survival time compared to those receiving chemotherapy alone.
Cynthia Pine, a renowned researcher at Queen Mary University of London, has received the IADR E.W. Borrow Memorial Award for her groundbreaking work on preventing childhood dental caries. Her research focuses on promoting oral health in disadvantaged communities and developing interventions to improve parents' key dental health behaviors.
A study at Queen Mary University of London has identified genetic mutations that occur early in the development of bowel cancer in patients with inflammatory bowel disease (IBD). These mutations could form the basis of a simple diagnostic test for predicting who is at high risk of developing IBD-associated colorectal cancer.
A £2 million project aims to improve asthma control in African schoolchildren, with a focus on 3,000 children aged 12-14. The study will use theatre performances to address asthma knowledge and stigma, and assess the barriers to achieving good control.
A new study by Queen Mary University of London found that 58% of online video piracy is concentrated in just two locations, making them susceptible to detection by copyright enforcers. The research also revealed a global network of streaming cyberlockers and third-party indexing services facilitating piracy.
Researchers found that American swamp sparrows accurately learn their songs 98% of the time, with a conformist bias strategy that filters out new song types. This leads to stable cultural traditions that can rival human customs in stability and longevity.
A new international study, led by Queen Mary University of London, will monitor the lung health of over 3,000 primary school children in polluted areas for four years. The CHILL study aims to determine if policies improving air quality can improve lung growth and reduce respiratory symptoms in children.
Researchers at Queen Mary University of London have developed a new method to create materials with remarkable precision and order, resembling dental enamel. This breakthrough could lead to the prevention and treatment of tooth decay and sensitivity, benefiting over 50% of the world's population.
Researchers developed a computer model that forecasts tumour changes, allowing for early disease course prediction and personalized treatment. The study reveals driver mutations can accelerate tumour growth by up to 30%.
A new surgery involving ultrasound energy has been found to significantly reduce blood pressure in patients with hypertension. The operation targets the nerves connected to the kidney and uses a one-hour procedure called 'renal denervation'. This could offer an alternative to lifelong medications for high blood pressure.
Researchers at Queen Mary University of London and University College London have identified 30 new gene locations that determine how the heart responds to exercise and recovers from it. This discovery could lead to the development of targeted therapies for abnormal heart rhythms and improved heart health.
Researchers created 3D hierarchically organised carbon structures using a supermolecular sponge and salt, enabling rapid charging and high capacities in Lithium-ion batteries. These nano-diatoms could also be used as electrocatalysts for hydrogen production.
Over 65s value technology to aid medication adherence, but prioritize familiarity and ease of use. Concerns include data security, dependence on tech, and consequences of failures.
A study led by Queen Mary University of London found that high-dose vitamin D supplements significantly boosted weight gain in malnourished children. Vitamin D supplementation also resulted in substantial reductions in delayed motor development and language development, with potential implications for the management of severe acute mal...
Researchers from Queen Mary University of London have identified a hormone imbalance as the underlying cause of treatment-resistant hypertension in around 10% of patients. The discovery highlights the potential benefits of spironolactone and amiloride in managing resistant hypertension.
Barts and The London School of Medicine and Dentistry has been allocated additional 32 new places for local medical students, providing opportunities for students from diverse backgrounds. This expansion aims to increase the number of primary care staff in the area following graduation.
A major international study found that pregnant women with severe anaemia are twice as likely to die during or shortly after pregnancy compared to those without the condition. The research suggests that prevention and treatment of maternal anaemia must remain a global public health priority.
A study published in PLOS ONE found that menopausal hormone therapy is not associated with adverse changes in cardiac structure and function, but may be linked to some healthier heart characteristics. The research examined 1,604 post-menopausal women and found significantly smaller left ventricular and left atrial chamber volumes.
Patients with cardiovascular disease have impaired levels of protective molecules in their blood in the morning, leading to increased risk of blood clots and heart attacks. Replenishing these molecules can improve cell behavior and reduce inflammation.
A new mathematical framework explains how rare events can cause major disruptions in complex networks like power grids and ecological systems. The framework correctly captures the effect of rare damage configurations observed in real networks, revealing discontinuous percolation transitions that lead to abrupt collapses.
A recent study found that thousands of children with oral pain in London are being taken to pharmacies and non-dental health services, resulting in unnecessary use of NHS resources. The study highlights the need for integrated systems and better referral processes to ensure children receive dental treatment as soon as possible.
Loss of protein PHLDA1 is sufficient for development of drug resistance to targeted therapy in endometrial and HER2-positive breast cancer cells. Rescuing PHLDA1 expression re-sensitises cancer cells to RTK inhibitor.
A new study by Queen Mary University of London aims to develop a 'beetroot pill' that could reduce the risk of kidney failure in patients undergoing coronary angiography. The research seeks to harness the antioxidant properties of dietary nitrate found in beetroot to prevent contrast-induced nephropathy, a common complication of the pr...
A study of nearly 800 postmenopausal women found that four commonly used prognostic breast cancer tests have varying abilities to predict disease recurrence. The tests, including Oncotype Dx and Prosigna Risk of Recurrence Score, were compared for their accuracy in predicting whether the cancer will return after five years.
Researchers developed a printing technique combining molecular self-assembly with additive manufacturing to create complex biological structures. This allows for the study of biological scenarios such as cancer growth and immune cell interactions, potentially leading to new drug development.
Researchers at Queen Mary University of London have discovered that cells can 'walk' on liquids using protein nanosheets with strong mechanical properties. This breakthrough could lead to the design of new cell technologies for regenerative medicine and tissue engineering.
A new study found that millions of unapproved antibiotics are being sold in India, with multinational companies manufacturing nearly 20% of the unapproved formulations. The researchers argue that banning the sale of unapproved FDC antibiotics and improving access to healthcare are crucial steps to controlling antimicrobial resistance.
Scientists at Queen Mary University of London have successfully generated an artificial adrenal gland using cells derived from urine. The new approach uses reprogramming to create steroid-producing cells that can model adrenal diseases and test personalized treatments for patients with adrenal insufficiency.
A new study invalidates the UK's folate intake limit, citing a 'flawed' analysis that has hindered efforts to prevent neural tube defects. The findings support mandatory fortification of flour with folic acid to protect babies from these birth defects.
Researchers at Queen Mary University of London discovered a new mechanism by which heart cells sense stiffness, involving both contraction forces and resting tension. The study found increased resting tension in heart cells after a heart attack or disease, leading to abnormal mechanosensing and signalling that contributes to heart fail...
Researchers at Queen Mary University of London have successfully modified a common flu virus to target and kill pancreatic cancer cells. The new technique could potentially become a promising new treatment for patients with the aggressive disease.
A mathematical model has been developed to explain how new ideas emerge, using Heaps' law and complex networks to analyze the discovery process. The study reveals that innovations often arise in clusters and are strongly correlated, providing insights for effective interventions to nurture sustainable growth.
Researchers found that population testing for multiple cancer genes is the most cost-effective strategy, preventing many more ovarian and breast cancers than current screening methods. This approach could save thousands of lives by reducing risk factors through enhanced screening, medical prevention, or risk-reducing surgery.
A recent study published in the British Journal of General Practice found that patients with multiple long-term health conditions are more likely to attend emergency departments. The study analyzed data from over 800,000 patients in east London and found a significant link between socioeconomic deprivation and ED attendance rates.
A study at Queen Mary University of London reveals a new gene, MAFA, that affects insulin-producing cells, leading to rare genetic forms of diabetes and insulinomas. The research found that the same gene defect can cause both high and low blood sugar levels in the same family.
A recent study found that at least 61% of people who try their first cigarette become daily smokers, suggesting the need to prioritize efforts to reduce cigarette experimentation among adolescents. The study analyzed data from over 215,000 survey respondents and published in the journal Nicotine & Tobacco Research.
A recent study by Queen Mary University of London found that protein markers are a more accurate predictor of patient responses to midostaurin, a new leukemia treatment. This breakthrough could lead to double the number of patients being treated and improve outcomes for those with acute myeloid leukemia.
A computational study by Queen Mary University of London has identified Botswana as the country with the most distinct musical recordings globally. The researchers found that China has the most spatial outliers compared to its neighboring countries, highlighting unique timbral characteristics such as the butterfly harp string instrument.
A study by Queen Mary University of London researchers found that robot drummer Mortimer's social media posts sparked significant human interaction, particularly when accompanied by photos and comments. Music proved to be a key factor in establishing believability and long-term engagement with the robot.
Researchers developed a molecular printing technique, 3DEAL, to create complex hydrogel environments with controlled chemical composition. This allows for the design of new drug screening platforms and tissue-engineered constructs with spatially controlled gradients or patterns.
Research led by Queen Mary University of London predicts a shift in cervical cancer burden from young to older women. Incidence among 50-54 year olds is expected to increase by 50%, while mortality rates are projected to rise by 109% among 60-64 year olds.
A groundbreaking gene therapy trial has shown that over one year on from a single treatment, participants with haemophilia A are showing normal levels of the previously missing protein, effectively curing them. The results have particular significance as the first successful gene therapy trial for the haemophilia A.
Researchers at Queen Mary University of London used harmonic radar technology to study how bees develop efficient routes. They found that experienced bees use a combination of visiting feeders in the same order and flying along habitual flight paths to reduce travel distance.
Researchers at Queen Mary University of London have identified a new weakness in medulloblastoma, the most common form of childhood brain tumour, which could lead to more targeted treatments. The study found that high levels of BMI1 and low levels of CHD7 are associated with poor prognosis in aggressive human medulloblastoma.