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Ruhr-University Bochum


High-frequency stimulation in pain medicine

Researchers have investigated high-frequency repetitive sensory stimulation as a therapeutic approach for Complex Regional Pain Syndrome (CRPS) patients. The study showed significant improvement in tactile performance after stimulation, with individual patients reporting substantial pain relief.

SourceRuhr-University Bochum·JournalFrontiers in Neurology·DateNov 20, 2015

Alzheimer's research: New findings

Researchers discovered that the protein APP forms spherical structures in the nucleus, affecting gene activity and neurotransmitter modulation. This finding may lead to new therapies for Alzheimer's disease by inhibiting neurotransmitter activity.

SourceRuhr-University Bochum·JournalCellular Signalling·DateNov 16, 2015

The brain's dress code

A functional magnetic resonance imaging (fMRI) study found that The Dress activates frontal and parietal brain areas, depending on perception. Researchers identified differential brain activity in participants perceiving the dress as white-gold versus black-blue.

SourceRuhr-University Bochum·JournalCortex·DateOct 14, 2015

Stress causes infants to resort to habits

Infants under stress exhibit less flexible behavior when presented with new situations, unlike adults who also show reduced flexibility due to stress. This study suggests that repeated exposure to stress in infancy may hinder knowledge acquisition and have lasting effects on cognitive development.

SourceRuhr-University Bochum·JournalProceedings of the National Academy of Sciences·DateSep 30, 2015

New method to better understand atomic nuclei

Physicists at Ruhr-University Bochum have developed a new approach to carry out precision calculations of the forces acting between protons and neutrons in atomic nuclei. This method uses effective field theory and a new method for analyzing theoretical uncertainties, allowing for a more accurate description of nuclear systems.

SourceRuhr-University Bochum·JournalPhysical Review Letters·DateSep 24, 2015

How the mind sharpens the senses

Researchers at Ruhr-University Bochum found that mental focussing can improve tactile acuity by 17 percent after a four-day Zen-retreat. This improvement is comparable to those achieved through intense long-term training or physical stimulation, challenging the current understanding of neuroplasticity.

SourceRuhr-University Bochum·JournalScientific Reports·DateAug 27, 2015

How cortisol reinforces traumatic memories

A study published in Neuropsychopharmacology found that cortisol enhances the consolidation of emotional memories, particularly in individuals with anxiety and Post-Traumatic Stress Disorder (PTSD). Cortisol levels can strengthen memories of traumatic experiences during both initial formation and reconsolidation after memory retrieval.

SourceRuhr-University Bochum·JournalNeuropsychopharmacology·DateJul 1, 2015

A protective shield for sensitive catalysts

A team of researchers has developed a hydrogel that can protect sensitive catalysts from oxygen-caused damage, making it possible to create efficient and affordable hydrogen fuel cells. The hydrogel acts as both solvent and protective environment, allowing the catalysts to remain functional even in high-oxygen concentrations.

SourceRuhr-University Bochum·JournalAngewandte Chemie International Edition·DateJun 15, 2015

Coral colonies more genetically diverse than assumed

Researchers at Ruhr-University Bochum discovered that coral colonies have higher genetic diversity than assumed, with 24-47% of polyps being genetically different. This increased diversity may help corals adapt to environmental changes, but is it sufficient to compensate for the devastating effects of climate change?

SourceRuhr-University Bochum·JournalMolecular Ecology·DateJun 10, 2015

In search of memory storage

Researchers at Ruhr-University Bochum recreated memory formation in the hippocampus using computer simulations, challenging the existing model. They found that the CA1 region plays a key role in completing memories, while the CA3 region is not as crucial as previously thought.

SourceRuhr-University Bochum·JournalPLOS Computational Biology·DateJun 3, 2015

Nerve cells in the fast lane

Dopamine-producing neurons play a crucial role in signal transmission, influencing motor control, reward behaviour, motivation, and impulse control. The discovery reveals that glutamate facilitates rapid signal transmission, enabling the brain to respond quickly to stimuli.

SourceRuhr-University Bochum·JournalNature Neuroscience·DateMay 12, 2015

Detecting lung cancer at an early stage

Researchers have developed a new diagnostic method called spectral histopathology that facilitates marker-free detection of individual subtypes of lung cancers. The accuracy of this method is higher than traditional histopathology, reaching over 92%, allowing for more precise diagnosis and personalized treatment options.

New emotion recognition model

Researchers at Ruhr-University Bochum propose a new model for emotion recognition, suggesting that humans can directly recognize emotions through pattern recognition. Even with sparse clues, humans can identify typical emotion patterns, including physiological reactions and facial expressions.

SourceRuhr-University Bochum·JournalMind & Language·DateApr 8, 2015

How we know where we are

A study by Ruhr-University Bochum scientists and colleagues identifies specific brain regions responsible for spatial memory. The researchers found that suppressing irrelevant activities improves spatial navigation accuracy.

SourceRuhr-University Bochum·JournalCurrent Biology·DateFeb 16, 2015

Citrus scent inhibits liver cancer

Researchers from Ruhr-University Bochum found that terpenes in citrus scents can inhibit liver cancer cell growth. The study discovered the signalling pathway used by (-)-citronellal and citronellol, two terpenes with anti-cancer properties.

SourceRuhr-University Bochum·JournalArchives of Biochemistry and Biophysics·DateJan 19, 2015

Sensor demonstrates lack of space in living cells

Researchers developed a novel sensor that changes color depending on the confinement of space in cells, demonstrating the effects of lack of space on protein behavior. The study reveals attractive forces inside cells that override compression effects, leading to changes in protein functions under osmotic stress.

SourceRuhr-University Bochum·JournalAngewandte Chemie International Edition·DateJan 5, 2015

Green light for clever algae

Guillardia theta's unique phycobiliproteins have distinct biosynthesis and assembly processes compared to cyanobacteria and red algae. Researchers gained insight into the complex transport mechanism of these pigments using docking enzyme GtCPES.

SourceRuhr-University Bochum·JournalJournal of Biological Chemistry·DateSep 26, 2014

'Funnel' attracts bonding partners to biomolecule

A team of scientists has found that water molecules form a 'funnel' around proteins, guiding them to potential binding partners. This collective water movement assists binding and supports the mutual recognition of biomolecules, allowing them to select or reject certain partners.

SourceRuhr-University Bochum·JournalJournal of the American Chemical Society·DateSep 24, 2014

The accelerator of molecular motors

Researchers identify Pex22p module as key component in peroxisomal Ub machinery, boosting enzyme import and degradation of pollutants. This discovery sheds light on peroxisomal disorders like Zellweger syndrome and highlights the importance of reevaluating familiar proteins.

SourceRuhr-University Bochum·JournalPLOS ONE·DateSep 22, 2014

Visualizing plastic changes to the brain

Researchers have successfully visualized the effects of transcranial magnetic stimulation (TMS) on neurons in real-time using voltage-sensitive dyes. The high-resolution imaging data may lead to optimized TMS parameters and learning processes for treating neurological diseases.

SourceRuhr-University Bochum·JournalProceedings of the National Academy of Sciences·DateSep 4, 2014

An 'anchor' that keeps proteins together

Researchers at Ruhr-University Bochum have discovered a new scaffold protein called PRO40 that plays a crucial role in the production of fruiting bodies in hyphae fungi. By binding to specific kinases, PRO40 enables signal transmission and regulates MAP kinase modules.

SourceRuhr-University Bochum·JournalPLOS Genetics·DateSep 4, 2014

Why HIV patients develop dementia

Researchers from Ruhr-University Bochum found that HIV-infected cells activate specific immune cells in the brain, leading to chronic inflammation and neuronal cell death. This discovery may help develop biomarkers and therapeutic strategies for HIV-associated neurocognitive disorders.

SourceRuhr-University Bochum·JournalExperimental Neurology·DateSep 3, 2014