Researchers have updated the lunar time scale to reflect advances in understanding the Moon's evolution after the Apollo era. The new scheme divides the Moon's history into three distinct phases: Eolunarian Eon, Paleolunarian Eon, and Neolunarian Eon.
Artificial intelligence (AI) is being applied to coronary CT angiography to improve image quality and automate calculations. This enables more accurate diagnoses and personalized treatments for cardiovascular diseases.
Modern semantic communication optimizes information transmission and error correction using natural redundancy, enabling end-to-end system-wide optimization. The Seb-based framework provides a new basic model for semantic information representation, with potential applications in Intellicise networks and various industries.
Researchers discovered a novel mechanism where iron catalysts modulate reactivity and selectivity through spin state changes. The study found that spin-delocalization interactions between iron and the ligand regulate the spin and oxidation states of the iron center.
This integrated study applies a new plate tectonics model to interpret major geological phenomena on Archean cratons, eliminating the illusion that continental crust did not originate from plate tectonics. The results provide insights into the evolution of early Earth and the origin of continental crust.
This study highlights the essential role of Mettl3 in regulating CD8 T cell response during acute infection, where its absence impairs effector differentiation and memory formation. The results show that Mettl3-dependent m6A modification sustains T-bet protein expression, allowing normal production and function.
Researchers successfully created a single-domain protein catenane that exhibits improved anti-aggregation properties and thermal resilience. The enzyme retains over 70% of its activity even after being heated to 70°C for 10 minutes.
Modern semantic communication technology has been developed to utilize natural redundancy in information transmission, enabling source compression and channel transmission optimization. This technology has potential applications in emerging fields like Intellicise networks and the metaverse.
Climate change will exacerbate heat-related work hours lost in China, with provinces like the south and east most affected due to higher temperatures and larger populations. Limiting global warming to 1.5°C can avoid substantial labor losses, equivalent to 0.6-1.4% of annual GDP.
The study reveals over 10,000 viral species in global supraglacial environments, driving biogeochemical cycling and ecosystem sustainability. These viruses interact with host microbes to promote metabolism, adaptation, and phenolic carbon use in hostile conditions.
The convergence of automation and AI in organic chemistry has led to a paradigm shift, enabling the development of self-evolving chemistry assistants. This integration is poised to unlock new possibilities in understanding reaction mechanisms and teaching organic chemical reactions.
Scientists create novel concept for all-weather CO2 utilization by mimicking natural photosynthesis, enabling round-the-clock and solar-driven CO2 conversion.
The FASHI survey has detected a total of 41741 extragalactic HI sources in the frequency range 1305.5-1419.5 MHz, covering approximately 35% of the total sky observable by FAST.
The convergence of automation and AI is revolutionizing organic chemistry research, introducing generative AI assistants that can learn and evolve. This shift enables new possibilities in understanding reaction mechanisms and heuristics.
A long-term study found that green manuring strengthens core microbiomes in soils, promoting organic C mineralization, N fixation, and N2O release. Keystone phylotypes were key to unlocking these functions across vertical soil profiles.
The study reconstructs the thermal and tectonic evolution of regional metamorphism at convergent continental margins, focusing on the East Tethys tectonic domain. The research reveals three types of regional metamorphism and associated geothermal gradients, shedding light on the tectonic transition from cold subduction to hot rifting.
Researchers successfully created a C4-like vein pattern in rice by modulating SHORT ROOT and auxin levels. This breakthrough sheds light on the antagonistic interplay between SHR and auxin, providing critical insights into C4 vein formation.
The study connects Tethyan plate tectonic movements to changes in Earth's surface environment, influencing global temperature and mineral resource distribution. Subduction-driven plate tectonics altered ocean-sea land distribution, affecting solar energy absorption and subsequent environmental shifts.
A fast urban micro-meteorology model was developed to assess regional weather and human comfort index in the central Beijing region. The model captured fine spatial structures of wind, air temperature, humidity, and comfort index, revealing blockage effects on wind fields and sun lights.
Researchers developed an engineered artificial gene circuit device to modulate drug resistance in bladder cancer treatment. The device reduces resistance to vincristine by downregulating the drug-resistant gene OIP5 and blocking other NF-κB-mediated pathways.
Researchers found that actual land cover changes affect surface temperatures differently across latitudes, with warming effects occurring more frequently and strongly than cooling effects. Global temperature increases due to LCCs accounted for up to 44.6% of overall concurrent warming.
Scientists successfully crystallized –COOH-functionalized gold nanoclusters using a novel biomimetic approach, revealing their crystallographic structure and paving the way for investigating their properties. The breakthrough method has broad implications for fields like chemosensing, biosensing, and materials science.
Researchers developed an accurate error prediction model and implemented soft-decision decoding to overcome limitations in hard-decision decoding, extending the upper limit of error correction to infinity.
The researchers developed an innovative approach to identify disease-causal microbes, controlling confounding factors and achieving high significance in statistical tests. VTwins significantly reduces the required sample size for identifying disease-associated microbial features.
A new Early Jurassic sauropodomorph dinosaur, Qianlong, contains three skeletons and five egg clutches, displaying leathery eggshell microstructures similar to other Cretaceous dinosaur eggs. The study suggests that the first dinosaur eggs were leathery, contradicting previous theories of soft or hard-shelled eggs.
The paper proposes an adaptive representation model for geoscience knowledge graphs that can efficiently represent complex spatiotemporal features and relationships. The model uses a unified spatiotemporal ontology to automatically adopt an adaptive tuple structure based on the association of spatiotemporal information.
Research finds that rainfall in southern China can trigger the formation of an anticyclonic anomaly over the Pacific Northwest, intensifying haze in the North China Plain. The study suggests a 27% contribution of rainfall to haze development, highlighting the need for closer monitoring of synchronized dynamics.
China's total N2O emissions increased from 889.6 Gg yr-1 in 1980 to 2295.0 Gg yr-1 in 2020, with agriculture making the largest contribution until 2015. However, industrial and energetic sources exceeded agriculture and became the fastest-accelerating N2O sources due to increasing demand for adipic acid and fossil fuels.
Researchers developed a new hydrogen therapy strategy using solid-state atomic hydrogen, which selectively eliminates reactive oxygen and nitrogen species. This approach promotes wound healing in diabetic wounds by remodeling the microenvironment and alleviating inflammation.
A recent study investigated sporadic early-onset Alzheimer's disease (EOAD), focusing on its clinical features and biomarkers. EOAD patients were found to have more severe executive function deficits, bilateral precuneus atrophy, and elevated phosphorylated tau protein levels compared to late-onset AD patients.
The research highlights the need for improved disaster prevention strategies in response to droughts and floods on the Qinghai-Tibet Plateau. The team proposed a method for predicting and warning of these events, as well as a technical framework for identifying risk-blocking points and adaptive regulation.
Researchers developed stable Lipiodol-drug emulsion with sustainable drug release profiles to improve HCC treatment. The novel microreactor enabled effective induction of ferroptosis in cancer cells via a pH-responsive mechanism, showing promise for transarterial embolization therapy.
Researchers successfully synthesized Chromene derivatives with AIE characteristics in an aqueous micellar system, exhibiting regiostructure-dependent fluorescence. The compounds were found to have potential for ER-specific imaging and modulating cell viability through substituent alteration.
This study uses genetic lineage tracing to investigate the adaptive mechanisms of pancreatic islet β cells in various mouse models of diabetes. The results show that β-cells expand through self-replication and rarely trans-differentiate into α or δ cells in young mice, but recover β-cell identity after remarkable dedifferentiation in o...
Research reveals GPCR signaling plays a crucial role in the immune microenvironment of EBV-induced cancers, influencing tumor growth and immune phenotypes. CCR1, a key GPCR, regulates EBV DNA replication, gene expression, and immune checkpoint activation.
A study on rhesus macaques found that spontaneous pelvic organ prolapse (POP) shares similar histological changes with human POP. The research also identified conserved molecular pathways underlying the disease, including ECM dysregulation and immune disorder.
This study tracks rural settlements' spatiotemporal regularity driven by rapid urbanization, revealing slower growth and widening differences. The analysis reveals uneven spatial distribution, with most counties experiencing a 'Convex-I' change type, often far from urban zones.
Researchers leverage neutron imaging to analyze lithium battery evolution, revealing in-depth insights into electrode composition and internal reactions. This technology helps address pressing issues like energy density and safety concerns.
Researchers developed non-planar dielectrics to harness weather-adaptive environmental energy, increasing pyroelectricity and triboelectric output. The new materials improve efficiency without consuming additional energy sources.
The CR-hvKP pathogen is simultaneously multidrug-resistant, highly virulent, and highly transmissible, posing a significant public health challenge. It has been reported in Asian clinical settings, with China being particularly affected.
A team proposes detecting deci-Hertz gravitational waves on the Moon's surface using an array of small laser interferometric seismometers. The experiment aims to observe changes in the Moon's shape and position caused by passing GWs, filling a gap in the GW spectrum covered by existing detectors.
Researchers generated a comprehensive single-cell atlas of postnatal liver development in pigs, uncovering 23 cell types and their dynamic changes. The study highlights the critical role of lymphoid cells in immune function and identifies key transcription factors regulating liver metabolism.
The study estimates a global lifetime cancer risk of 25.10%, with significant differences between countries and regions, as well as between men and women.
Oceanic lithosphere is hydrated through two stages: initial hydration at mid-ocean ridges and secondary hydration at subduction zones. The study found that subduction-related process contributes to most of the mantle hydration, playing a crucial role in plate tectonics and Earth's water cycle
Researchers developed a method to produce highly strong and tough silk by feeding silkworms with rare earth ion-modified diets. The incorporated ions enhance mechanical performance through chemical interactions.
The study revealed that PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation, enabling P. aeruginosa to adapt to environmental stress and exhibit increased virulence. This unique regulatory mechanism provides new insights into the structure-function relationship of TetR family regulators.
Scientists create nanoreactor catalyst that significantly improves hydrogenation performance through reactant enrichment. The catalyst, Pt NPs@MnOx, exhibits high catalytic activities and selectivity in various reaction conditions.
Researchers developed a quasi-eutectic electrolyte to regulate the manganese cathode interface in zinc-manganese batteries. The electrolyte increases electrode potential and limits desolvation of zinc ions, resulting in improved stable kinetics during cycling. This leads to higher capacity retention rate, lower voltage polarization, an...
This paper surveys chip design with ML algorithms from an algorithmic perspective, proposing a novel taxonomy for target problems. The authors classify problems into regression, search, and generation problems, and discuss existing works in terms of these problems and corresponding ML algorithms.
A new study prioritizes risk genes at CRC GWAS loci by integrating multi-omics data, identifying 105 high-risk genes. These genes are associated with characteristics of CRC risk genes and are essential for CRC cell growth. The study suggests that integrating multi-omics data can propose candidate risk genes with high confidence.