Prof. George P. Chrousos has made significant advancements in endocrine research, especially in stress biology and the HPA axis. His work has opened new horizons in understanding complex human disorders such as anxiety, depression, and metabolic syndrome.
Researchers found geographical differences in PCOS symptoms among Black and white women, with regional variations affecting body mass index and hormone levels. The study suggests genetic and environmental influences on the disease's manifestation, highlighting the need for precision medicine tailored to specific needs.
The Endocrine Society advocates for a personalized approach to telehealth visits in endocrine care. This policy perspective highlights the benefits of incorporating telehealth into care plans, including increased convenience and reduced disparities in healthcare access.
Children born to mothers with gestational diabetes and obesity are twice as likely to develop attention-deficit/hyperactivity disorder (ADHD), according to a new study. The researchers found that excessive weight gain during pregnancy was a significant risk factor for ADHD in offspring, but not within normal weight gain ranges.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that vegan participants who engaged in regular resistance training had stronger bones than those who did not. The study also showed that vegans and omnivores who performed resistance training had similar bone structure.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that people with sedentary lifestyles and unhealthy sleep behaviors are at risk for developing fatty liver disease. Moderate improvement in sleep quality was related to a 29% reduction in the risk for fatty liver disease.
A new study found that growth hormone reduces liver fat and inflammation in patients with nonalcoholic fatty liver disease, improving liver function tests and markers of inflammation. The study showed significant improvements in liver health after administering growth hormone to 41 participants for 6 months.
A mouse study suggests that active testosterone therapy can lead to fewer and less developed eggs retrieved during IVF. Discontinuing testosterone therapy appears to have no significant impact on reproductive capacity, however.
Research suggests that high fructose consumption is associated with a higher chance of developing non-alcoholic fatty liver disease (NAFLD), especially among Mexican Americans and non-Hispanic Blacks. The study analyzed data from over 3,200 participants and found that those consuming the highest amount of fructose were at greatest risk.
Research presented at the Endocrine Society's annual meeting found that COVID-19 pandemic stress led to disturbed ovulation in many women. Nearly two-thirds of participants experienced short luteal phases or anovulation, indicating a significant impact on reproductive health.
A study of 56 transgender youth found that longer treatment with puberty-delaying medications was associated with lower bone mineral density. The researchers recommend discussing the impact of these medications on bone health and exploring interventions to improve bone health.
A new study found that teens' consumption of ultra-processed foods decreased significantly during the COVID-19 pandemic and continued to decline even after restrictions eased. This reversal took place due to changes brought by the pandemic, including school closures and working from home.
A new study found that women with obesity have suppressed ovarian follicle development and reduced production of reproductive hormones, which may underlie reduced fertility. The researchers also discovered that luteal phase defects are more prevalent in obese women during natural ovulatory cycles.
A new study presented at ENDO 2022 found that inactivated and mRNA COVID-19 vaccines do not cause significant fluctuations in thyroid function or increase the risk of emergency department visits among patients treated for hypothyroidism. The research suggests that these vaccines can be a safe option for this vulnerable population.
A new study found a strong association between prediabetes and an increased risk of heart attacks, with patients having prediabetes being 25% more likely to experience a heart attack. The researchers also discovered that those with prediabetes were at higher odds for requiring percutaneous intervention and heart bypass surgery.
A new study suggests that probiotic bacteria, particularly Lactobacillus, may enhance the effectiveness of tamoxifen and other endocrine-targeted therapies in reducing ER+ breast cancer risk. The researchers found elevated levels of Lactobacillus in breast tissue of mice treated with tamoxifen, leading to decreased breast tumor formation.
A new study found that parabens increase the growth, invasion, and expression of genes linked to cancer in breast cancer cells from Black women. This effect was more pronounced in Black cell lines compared to white cell lines.
A new study by Vertice Pharma confirms that drinking coffee does not affect the absorption of a liquid formulation of levothyroxine. The research suggests that patients can take their medication with coffee without worrying about reduced absorption. This finding could lead to more flexibility in dosing and improved patient outcomes.
A Phase 3 study found fezolinetant to significantly reduce the frequency and severity of moderate-to-severe vasomotor symptoms associated with menopause. The treatment also improved sleep disturbances, supporting its use for treating moderate-to-severe hot flashes.
Researchers developed an AI model to analyze thyroid ultrasound images, identifying nodules unlikely to be cancerous with a sensitivity of 97%. This technology could reduce the number of unnecessary biopsies and assist radiologists in choosing which nodules should undergo biopsy.
Research found that patients using insulin have a higher risk of fractures compared to those using metformin, particularly in non-obese and well-controlled diabetic patients. Routine fracture risk assessments are recommended for these individuals.
Research finds prenatal exposure to BPA and DEHP may contribute to mood disorders later in life by altering brain chemistry. Adult offspring exposed to these chemicals displayed impaired fear responses and altered behavioral patterns, highlighting the importance of avoiding exposures during pregnancy.
A randomized controlled trial shows significant improvements in testosterone replacement therapy for men with poorly-controlled type 2 diabetes and hypogonadism. The treatment improved symptoms, libido, and quality of life, as well as delayed verbal recall, a potential early sign of dementia.
Two experimental male contraceptive pills, DMAU and 11β-MNTDC, have shown promising results in lowering testosterone levels without unacceptable side effects. The study found that 75% of men who took the active drug were willing to use it in the future, compared to 46.4% of those taking a placebo.
A study finds that adults with growth hormone deficiency (GHD) experience higher rates of endocrine and metabolic conditions, as well as cardiovascular disease. Daily somatropin injections improve quality of life, but treatment rates remain low.
Research finds no significant increase in cardiovascular events among men with low testosterone undergoing testosterone treatment. Testosterone was found to reduce serum total cholesterol and triglycerides, but no significant differences were seen in other parameters.
The Endocrine Society's ENDO 2022 news conferences will showcase the latest research on diabetes, obesity, thyroid health, and reproductive conditions. Key findings include the impact of chemicals in hair care products on breast cancer cells and the effects of childhood obesity on male infertility.
A recent study published in Endocrinology found that exposure to a scream sound may lead to diminished ovarian reserve and decreased fertility in female rats. The researchers discovered that the scream sound reduced estrogen and Anti-Mullerian hormone levels, as well as the number and quality of eggs, resulting in smaller litters.
A new study published by The Endocrine Society suggests that exposure to per- and polyfluoroalkyl substances (PFAS) and phthalates may impair bone health in male teenagers. Researchers analyzed urine and blood samples from over 800 adolescents, finding an association between certain PFAS and phthalates and reduced bone mineral density.
A study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that undertreatment with thyroid hormone replacement can lead to longer hospital stays and higher readmission rates. Patients with high TSH levels before hospitalization had a 49% higher risk of 30-day readmission.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that people with type 2 diabetes and cognitive impairment have a higher risk of heart attack and stroke. Cognitive function may predict a person's future risk of heart disease, according to researchers.
The Endocrine Society's scientific statement highlights the potential of extracellular vesicles in diagnosing and monitoring endocrine-related conditions, including cancer. These tiny vesicles may also serve as biomarkers for high blood pressure and have therapeutic roles.
A new study found that Black people with diabetes were more likely to develop life-threatening complications like diabetic ketoacidosis during the pandemic. The disparity persisted even before the COVID-19 pandemic and was present in 45% of Black people, compared to 16% of White people.
A study published by The Endocrine Society found that eating potatoes in the morning, whole grains in the afternoon, and less processed meat in the evening may improve long-term survival in people with diabetes. This eating pattern is associated with better heart health outcomes.
Researchers found that long or irregular menstrual cycles in young women are associated with an increased risk of nonalcoholic fatty liver disease (NAFLD). NAFLD is a chronic condition where excess fat builds up in the liver, increasing the risk of death. Lifestyle changes can help reduce the risk of NAFLD in these women.
Research found walkable neighborhoods with access to parks and outdoor activities are associated with a lower risk of obesity and diabetes. Studies showed that living in highly walkable areas reduced the incidence of pre-diabetes by up to 50% compared to low walkability areas.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obesity may increase the risk of end-stage kidney disease in women with type 2 diabetes. Managing blood pressure and sugar levels is not enough to slow progression, emphasizing the need for weight management.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that men with high levels of body fat are more likely to have lower bone density and an increased risk of fractures. The researchers analyzed data from over 10,800 people under 60 years old and found a strong positive association b...
A small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that men with hypersexual disorder have higher oxytocin levels than healthy men. Cognitive behavioral therapy was effective in reducing both hypersexual behavior and oxytocin levels in participants.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that abnormal thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems. Mothers with high thyroid hormone levels were more likely to have withdrawn, anxious, or depressed sons.
A small study published in the Journal of Clinical Endocrinology & Metabolism found that exercising at high altitude can lead to lower blood sugar levels in individuals with type 1 diabetes. This may increase the risk of hypoglycemia, which can be life-threatening if not treated promptly.
Research highlights growing health disparities in diabetes technology adoption between Black and white Medicare patients. Insulin pump and CGM use increased among all groups, but widened gap found between racial groups.
A new study suggests that novel obesity treatments such as modulation of the gut microbiome and gene therapy could help end the obesity epidemic. However, lack of insurance coverage and cost issues create barriers to treatment. Researchers are working on developing safer and more effective medications with fewer side effects.
A clinical trial found that a green Mediterranean diet rich in leafy greens like Mankai and green tea can elevate fasting ghrelin levels, reducing belly fat and improving insulin sensitivity. This approach may also have additional cardiometabolic benefits.
Researchers explore science behind time-restricted eating, finding it improves sleep quality and reduces obesity, diabetes, and heart disease risk. By aligning daily habits with internal rhythms, intermittent fasting can optimize health and reduce chronic disease burden.
A new study estimates that treating polycystic ovary syndrome (PCOS) costs the US $8 billion a year, primarily due to long-term metabolic health conditions like diabetes and cardiovascular disease. The analysis also found pregnancy-related costs contribute significantly to the total burden.
A recent study found that women with higher levels of PFAS in their system are 20% more likely to stop breastfeeding early. This is significant because almost every human on the planet is exposed to these endocrine-disrupting chemicals, which can have detrimental effects on reproductive health.
A review article published in the Endocrine Society's journal Endocrinology predicts a peak in population numbers in 2064 followed by a 50% drop by the end of the century. Stress from less quality social interactions is believed to suppress sperm count, ovulation, and sexual activity, contributing to declining reproduction rates.
Research suggests that antidepressant treatment can improve outcomes for individuals with comorbid diabetes and depression, reducing the risk of serious complications such as heart disease. Regular adherence to antidepressants is associated with better diabetes management and quality of life.
Antacids have been found to lower HbA1c levels by 0.36% and fasting blood sugar by 10 mg/dl in individuals with diabetes. However, taking antacids had no effect on the risk of developing diabetes in non-diabetic individuals.