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University College London


Climate change likely to aggravate brain conditions

A UCL-led team of researchers warn that climate change will aggravate brain conditions such as stroke, migraine, and dementia. The study, which reviewed 332 papers, found that extreme temperatures and weather events can disrupt sleep, exacerbate cognitive impairment, and lead to increased hospital admissions and mortality.

SourceUniversity College London·JournalThe Lancet Neurology·TypeCommentary/editorial·DateMay 15, 2024

Women are 40% more likely to experience depression during the perimenopause

A new study published in the Journal of Affective Disorders found that women in the perimenopausal stage are significantly more likely to experience depression. The meta-analysis of seven studies involving over 9,000 women from around the world reveals a 40% increased risk of depressive symptoms during this life-stage.

SourceUniversity College London·JournalJournal of Affective Disorders·TypeMeta-analysis·DateApr 30, 2024

Pressure in the womb may influence facial development

A recent study published in Nature Cell Biology found that increased hydrostatic pressure can hinder the healthy development of neural crest cells, leading to an increased risk of facial malformations. The researchers suggest that physical cues in the womb, such as pressure, may play a role in shaping facial features.

SourceUniversity College London·JournalNature Cell Biology·TypeExperimental study·DateApr 22, 2024

Humans pass more viruses to other animals than we catch from them

Researchers found that humans transfer viruses to domestic and wild animals at a rate twice that of animal-to-human transmission, highlighting the importance of monitoring viral exchange between species. This study's findings have significant implications for understanding zoonotic diseases and conservation efforts.

SourceUniversity College London·JournalNature Ecology & Evolution·TypeData/statistical analysis·DateMar 25, 2024

New classification of tuberculosis to support efforts to eliminate the disease

Researchers have developed a new framework for classifying tuberculosis (TB) that replaces the traditional binary approach with four disease states: clinical, subclinical, infectious, and non-infectious. The International Consensus for Early TB (ICE-TB) framework aims to improve diagnosis and treatment of early-stage TB, which has hist...

SourceUniversity College London·JournalThe Lancet Respiratory Medicine·TypeSurvey·DateMar 22, 2024

Supply chain disruptions will further exacerbate economic losses from climate change

A new study finds that climate change will further exacerbate projected economic losses from global warming when its impact on global supply chains is factored in. By 2060, total GDP losses could amount to between $3.75 trillion and $24.7 trillion, with supply chain disruptions accounting for a significant proportion of these losses.

SourceUniversity College London·JournalNature·TypeData/statistical analysis·DateMar 13, 2024

New treatment could transform the mental health of children with epilepsy

A new treatment has been shown to reduce mental health difficulties in children with epilepsy compared to standard care. The Mental Health Intervention for Children with Epilepsy (MICE) treatment uses a modular approach to treat multiple conditions simultaneously, reducing the likelihood of psychiatric disorders by 40%.

SourceUniversity College London·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateMar 7, 2024

Most smokers in England wrongly believe vaping is at least as harmful as smoking

A study led by UCL researchers found that over half of English smokers believe vaping is equally or more harmful than smoking. The survey data showed a sharp increase in perceived harm from 2021, coinciding with rising youth vaping rates. Better communication about health risks is needed to help smokers make informed choices.

SourceUniversity College London·JournalJAMA Network Open·TypeObservational study·DateMar 1, 2024

Vest can detect earlier signs of heart muscle disease

A new vest can map electric impulses of the heart in fine detail, detecting abnormalities from a potentially fatal heart disease much earlier. The study found that the vest identified electrical changes among 1 in 4 individuals with a gene mutation for whom no signs of disease were detected via standard tests.

SourceUniversity College London·JournalJournal of the American College of Cardiology·TypeObservational study·DateFeb 28, 2024

Avid appetite in childhood linked to later eating disorder symptoms

A new study found that high food responsiveness in early childhood is linked to a higher likelihood of experiencing eating disorder symptoms in adolescence. Children who exhibited high levels of hunger and desire for food were more likely to develop binge eating, emotional eating, and restrictive eating behaviors.

SourceUniversity College London·JournalThe Lancet Child & Adolescent Health·TypeObservational study·DateFeb 20, 2024

Hostile environment policies linked to prolonged distress in people with Black Caribbean ancestry

A new study published in The Lancet Psychiatry found a causal link between government policies and mental health decline in people with Black Caribbean heritage. The research team analyzed data from over 58,000 participants and found an increase in psychological distress after the 2014 Immigration Act and the Windrush scandal.

SourceUniversity College London·JournalThe Lancet Psychiatry·TypeObservational study·DateFeb 13, 2024

Teenagers need better reproductive health education to tackle parenthood fears

Two new studies by UCL researchers found that nearly half of teenagers are worried about having children due to fear, self-doubt, and lack of education on reproductive health. The studies also highlighted gaps in sex education, with many students expressing concerns about endometriosis, infertility, and the impact of lifestyle on ferti...

SourceUniversity College London·JournalHuman Fertility·TypeSurvey·DateFeb 12, 2024

Generative AI helps to explain human memory and imagination

A new study using generative AI models simulated how the brain learns and remembers events, revealing how memories are re-constructed in our minds. The model showed how the hippocampus and neocortex work together to create efficient 'conceptual' representations of scenes, enabling us to both recall past experiences and imagine new ones.

SourceUniversity College London·JournalNature Human Behaviour·TypeComputational simulation/modeling·DateJan 19, 2024

Nurse home visits have a lasting impact for disadvantaged mothers and daughters

A new analysis of health data found that prenatal and infant nurse home visits significantly reduced the likelihood of daughters being obese by 55% and mothers experiencing hypertension by 39%. The study also showed a decrease in severe obesity and Stage 1-2 hypertension in adolescence. Early intervention through public programs like n...

SourceUniversity College London·JournalJAMA Network Open·TypeMeta-analysis·DateJan 18, 2024

Heart vest could help predict sudden cardiac death risk

A new study by UCL researchers suggests that a vest mapping the heart's electrical activity could help identify people at high risk of sudden cardiac death. The electrocardiographic imaging (ECGI) vest combines signals with MRI images to generate 3D models, potentially predicting risk factors for life-threatening heart rhythms.

SourceUniversity College London·JournalJournal of Cardiovascular Magnetic Resonance·TypeRandomized controlled/clinical trial·DateDec 18, 2023

New gene therapy could significantly reduce seizures in severe childhood epilepsy

Researchers at UCL Queen Square Institute of Neurology have developed a new gene therapy that significantly reduces seizures in mice with focal cortical dysplasia. The treatment, which involves the overexpression of a potassium channel, has shown an average reduction of 87% in seizures without affecting the mouse's memory or behavior.

SourceUniversity College London·JournalBrain·TypeExperimental study·DateDec 14, 2023