Researchers at the University of Bonn and Cardiff develop a new observational strategy for imaging extremely distant galaxies, using ALMA radio telescope data. This method improves upon previous efforts by accurately estimating molecular hydrogen presence in these galaxies, providing insights into galaxy formation and star creation.
Scientists at the University of Bonn have discovered a new signaling pathway that utilizes adenosine to stimulate brown fat cells. This 'browning' process may help convert white fat cells into energy-burning brown cells, potentially aiding in weight loss and reducing the risk of chronic diseases.
Researchers at the University of Bonn discovered a previously unknown nerve cell shape that allows signals to be transmitted directly from dendrites to axons, bypassing the cell body. This unique structure facilitates faster and more efficient communication between neurons.
Researchers led by the University of Bonn have found that the MERS virus has a low transmission rate from person to person, but is still a deadly disease. The study, published in the New England Journal of Medicine, also suggests that dromedaries may be an additional source of infection.
Scientists have isolated a mutated polio virus that can evade the immune system and render vaccinations ineffective. This discovery is alarming as it threatens to undermine progress made in eradicating polio, which has been nearly eradicated thanks to effective vaccination.
An international team of researchers from the University of Bonn Hospital and the London Research Institute have now discovered that our immunosensory system attacks viruses on a molecular level. This means a healthy organism can keep rotaviruses, a common cause of diarrheal epidemics, at bay.
Ancient insect inclusions in Baltic Sea amber reveal a surprising similarity with Asian forms, dating back 40-50 million years. This discovery fills a long-standing gap in the understanding of species migration between continents.
A team of researchers found that inflammasomes remain active even after cell death, triggering a rapid inflammatory reaction. This discovery offers potential novel approaches for therapies against diseases such as gout, atherosclerosis, and Alzheimer's disease.
Researchers at the University of Bonn developed a novel camera system that can see around corners without mirrors, using diffusely reflected light to reconstruct object shapes. The system records time-resolved data from light echoes, which brings valuable information about object shape and appearance.
Researchers have taken 'snapshots' of a critical receptor involved in blood coagulation, paving the way for novel, reversible blood-thinning substances. These new therapies aim to provide more effective control over platelet aggregation, reducing side effects and improving patient outcomes.
Researchers have found that caffeine can positively affect tau deposits in Alzheimer's disease, improving spatial memory and reducing pathogenic processes in genetically altered mice. The study suggests a new class of drugs may be developed for the treatment of Alzheimer's disease using an A2A antagonist.
Scientists at the University of Bonn identified Creld1 as a crucial gene for heart valve development in mice, which also functions similarly in humans. This discovery may lead to improved diagnosis of unidentified heart valve diseases and better understanding of cardiac development.
Researchers found a connection between the DRD2 gene variant and everyday lapses in attention, including forgetfulness. The study suggests that individuals with this genetic variation are more likely to experience short-term memory lapses and distraction, which can have consequences in daily life.
Researchers identified two new gene regions associated with bipolar disorder and confirmed three existing ones through a massive international collaboration. The study analyzed genetic data from over 9,400 patients and found that these genes work together with environmental factors to contribute to the disease.
Researchers discovered that sunburns contribute to melanoma development through inflammatory processes in surrounding tissue. Melanoma cells migrate along blood vessels in inflamed skin, with activated neutrophils playing a key role in metastasis.
Immunologists at the University of Bonn have disproved a long-held classification of immune cells, finding that macrophages can take on multiple forms. This discovery offers new hope for treating diseases such as arthritis, diabetes, and cancer.
Researchers at the University of Bonn have decoded a new immunoregulatory mechanism controlling defense in urinary tract infections. The mechanism involves two types of macrophages regulating neutrophils, with sentinel macrophages triggering an alarm and helper macrophages providing a safety mechanism to prevent collateral damage.
Researchers at the University of Bonn have developed an app that measures cellphone use, revealing shocking statistics. The app, dubbed Menthal, analyzes user behavior over six weeks, showing average users activate their smartphones every 12 minutes, and problematic use can lead to addiction-like symptoms.
Researchers discovered HDL acts upon inflammatory processes by activating ATF3, downregulating chronic inflammation in macrophages. This finding suggests a molecular approach for treating inflammation in diseases like diabetes.
Scientists transform skin cells into nerve cells from patients with Alzheimer's disease and test several non-steroidal anti-inflammatory drugs. The results show that these compounds have no effect on the harmful beta-amyloid aggregates in human neurons, unlike in animal models.
Researchers found that oxytocin administration increases attractiveness of partner and strengthens monogamy by stimulating brain's reward center. The study suggests a biological mechanism for maintaining love relationships.
A research team at the University of Bonn discovered a novel receptor that allows the immune system to recognize dangerous invaders and elicits an immune response. This receptor is found in Europeans but not in early men, suggesting it was inherited from Neanderthals.
Researchers from Bonn University discovered that immature nerve cells secrete chemical attractants that prevent mature brain cells from migrating into the brain. Inactivating these attractants improves nerve cell migration in animal models, offering a promising universal approach to treat Parkinson's and Huntington's diseases.
Researchers have developed a novel type of OLED that shows promise for high conversion efficiencies, potentially leading to cheaper displays. The new compounds can store electrical energy for longer periods, allowing for more efficient light generation and reduced heat production.
Archaeologists at the University of Bonn have discovered a 1,400-year-old mass grave containing 24 skeletons from the Maya civilization. The remains show signs of violent death and dismemberment, including decapitation and hatchet marks.
Researchers at Bonn University have discovered that UV-light induced DNA damage triggers lupus-like autoimmune symptoms by activating the cGAS signaling pathway. This study provides a crucial understanding of the immune mechanism behind lupus and offers potential new therapy targets.
Researchers discovered a 165-million-year-old fossilized skeleton of the ancient mammal Megaconus mammaliaformis in Northeast China. The animal had striking cusps on its teeth for crushing hard plant material and powerful jaws for eating tough plants.
Researchers have found a virus in South African bats that is genetically more closely related to MERS-CoV than any other known virus. This discovery suggests that African bats may play a role in the evolution of MERS-CoV predecessor viruses, potentially leading to human infection through intermediate hosts such as camels.
Researchers at the University of Bonn used computer simulations to show that seismic waves can focus over long distances, triggering mud eruptions. The study found that a dome-shaped structure under the mud volcano focused energy into the mud layer, liquifying it and injecting it into nearby faults.
Scientists at Bonn University Hospital and MPI Cologne developed a method to predict temporal lobe epilepsy surgery success rates, achieving 96% accuracy for female patients and 94% for males. The algorithm assesses brain images to differentiate between seizure-free and non-seizure-free patients.
Researchers from Bonn University found that particulate matter salt compounds can decrease the drought tolerance of trees, leading to forest decline. The study reveals a physical mechanism where deliquescent salts form wick-like structures that remove water from leaves, promoting dehydration.
Researchers found that markets significantly lower moral standards, with subjects willing to accept killing a mouse for money. In market conditions, people focus on competition and profits over moral concerns, leading to an erosion of moral values.
Scientists decode a 'toggle switch' in mice that significantly stimulates fat burning by converting white fat cells into brown fat cells, potentially combating obesity.
Researchers at Bonn University Hospital have deciphered the mechanism of CMA, a long-forgotten antiviral candidate. The study reveals that the compound stimulates the immune system in mice but not humans due to differences in receptor structure. This discovery inspires the search for an effective antiviral drug.
Researchers from the University of Bonn have found the oldest known dinosaur embryos in China, shedding light on the rapid growth and high reproductive rate of these ancient animals. The discoveries provide valuable insights into the biology of dinosaurs, including their development and behavior.
Researchers at Bonn University Hospital have achieved remarkable results using deep brain stimulation to treat treatment-resistant major depression. In six out of seven patients, symptoms improved considerably and rapidly, with significant improvements observed in anxiety, despondence, listlessness, and joylessness.
Researchers developed a method to reduce scar tissue and improve cardiac function in mice after a heart attack. The treatment uses microbubbles that oscillate with focused ultrasound, stimulating growth hormones and improving circulation.
Researchers found that tiny single-cell organisms are spreading rapidly through the world's oceans, stabilizing coastlines and reefs with their calcareous shells. By 2100, these protozoa may spread closer to the poles, occupying ecological niches left by corals.
Scientists at the University of Bonn have identified a new signaling pathway involved in chronic inflammation, which contributes to nerve cell malfunctions and death. By deactivating key genes, they observed reduced inflammation, memory loss, and beta-amyloid peptide deposition in genetically modified mice.
Bisphenol A, a widely used industrial chemical, has been shown to block essential calcium channels in human and mouse cells. This can lead to adverse effects on heart muscle contraction, enzyme activity, and nerve cell communication. The study suggests that alternatives to BPA should be developed to replace it in various products.
Researchers at the University of Bonn have decoded a possible mechanism for hybrid corn's high yield, finding that more genes are active in hybrid plants than in their homozygous parental lines. This increase in gene activity could lead to increased growth and vigor in hybrids.
Researchers from the University of Bonn have developed a new humanoid robot called NimbRo-OP, which is designed to facilitate research on humanoids. The robot's open-source design plan and source code aim to enable other researchers to use it as a basis for their work.
Melanoma cells can temporarily alter their external characteristics to become invisible to defense cells, allowing them to evade destruction. This knowledge forms an important foundation for improving combination therapies and may also be relevant to treatment with inhibitors of signal transmission in tumor cells.
Researchers found that testosterone-treated subjects lied less frequently than placebo-treated subjects in a dice game experiment. This result challenges the common perception of testosterone as promoting aggressive behavior and suggests that it may increase pride and the need for self-image.
The NCAN gene plays a major part in how manias manifest, being closely correlated with manic symptoms but not depressive episodes. Researchers found that knockout mice lacking the NCAN gene exhibited increased hyperactivity and reward-seeking behavior, responding well to lithium therapy.
A study by the University of Bonn found that a genetic variation on the CHRNA4 gene is associated with internet addiction. This variation occurs more frequently in women and may be related to social media use. The researchers hope their findings will lead to better therapies for online addiction.
Scientists have decoded signals that boost the burning of fat, focusing on the conversion of white fat cells into beige fat cells. Beige fat cells are efficient at converting energy from food into heat and can form from white fat cells.
Researchers studied Dead Sea sediment cores to reconstruct climate conditions over the past 10,000 years, finding rapid changes between moist and dry phases. They linked pollen data to plant species that can tolerate specific temperature and precipitation levels.
Researchers from University of Bonn discover most massive stars form double systems, with over three-quarters orbiting a companion. The study reveals material transfer and merging between stars, challenging previous assumptions about single stars.
Researchers have successfully split a single atom into its two halves, pulled them apart and reunited them again. This achievement showcases the potential of quantum mechanics in simulating complex systems, such as topological isolators and photo¬synthesis.