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University of Bonn


Natural killer cells have a memory

Researchers discovered that natural killer cells can remember and target pigmented skin cells, potentially treating malignant melanoma and vitiligo. The immune system uses the NLRP3 inflammasome as a checkpoint to trigger this response.

SourceUniversity of Bonn·JournalImmunity·DateJun 7, 2016

Plants are 'biting' back

Researchers from Bonn University discovered calcium phosphate as a structural biomineral in rock nettle plants, providing them with a hardened defense mechanism against herbivores. The unique material, structurally similar to reinforced concrete, is used instead of silica or calcium carbonate in most plants.

SourceUniversity of Bonn·JournalScientific Reports·DateMay 19, 2016

Fine-tuning for intestinal immune cells

A new study reveals that food components can significantly influence the intestinal immune system by binding to an important controller, the Ah receptor. The researchers found that the interaction between the Ah receptor and its repressor is crucial for balancing the immune response.

SourceUniversity of Bonn·JournalScientific Reports·DateMay 17, 2016

Got good fat?

University of Bonn researchers have discovered a new method to measure the activity of energy-consuming brown fat cells in humans and mice. They found that microRNA-92a can be used as an indirect measure of brown fat cell activity, with a small blood sample sufficient for analysis.

SourceUniversity of Bonn·JournalNature Communications·DateApr 27, 2016

Mathematics to fight cancer

Mathematicians and physicians at the University of Bonn have developed a new model for immunotherapy of cancer. The method describes how tumor cells change their external appearance in response to treatment, making it difficult for T-cells to recognize them as harmful.

SourceUniversity of Bonn·JournalScientific Reports·DateApr 12, 2016

Ring-shaped sugar helps in cases of atherosclerosis

Researchers at the University of Bonn discovered that cyclodextrin promotes the breakdown of cholesterol deposits in arteries, reducing inflammation and plaque formation. The ring-shaped sugar increases natural mechanisms for cholesterol breakdown and reduces inflammatory response, offering a potential new treatment for atherosclerosis.

SourceUniversity of Bonn·JournalScience Translational Medicine·DateApr 6, 2016

Researchers at the University of Bonn boost fat-burning

A team of scientists at the University of Bonn discovered a switch that can convert unwanted white fat cells into energy-burning brown cells by blocking Gq proteins. This breakthrough has significant implications for obesity treatment, as it may lead to the development of pharmaceutical products that target this pathway.

SourceUniversity of Bonn·JournalNature Communications·DateMar 9, 2016

Injustice can spread

A study published in Scientific Reports found that writing a message to the perpetrator can disrupt the chain of unfair behavior, calming negative emotions and leading to fairer interactions. The researchers suggest this strategy as a way to stop the spread of injustice.

SourceUniversity of Bonn·JournalScientific Reports·DateFeb 29, 2016

Extreme events in the brain

Researchers at the University of Bonn have developed a new model that simulates the behavior of neurons in the brain during extreme events, such as epileptic seizures. The model reveals how small-world networks can exhibit spontaneous changes, shedding light on the conditions under which these events develop.

SourceUniversity of Bonn·JournalPhysical Review X·DateFeb 26, 2016

Breaking through insect shells at a molecular level

Scientists at the universities of Bonn and Leipzig found a way to break through insect shells using enzyme chitinase 2 and growth factor idgf6. This discovery offers new starting points for controlling agricultural parasites and disease-carrying insects, such as mosquitoes that spread Zika virus.

SourceUniversity of Bonn·JournalScientific Reports·DateFeb 3, 2016

Climate change: Ocean warming underestimated

Researchers at the University of Bonn used satellite data to find that ocean warming expansion contributed an average of 1.4 millimeters per year to sea level rise, more than double the previous estimate of 0.7-1.0 millimeters per year. This could lead to significantly increased risks of storm surges and coastal flooding.

SourceUniversity of Bonn·JournalProceedings of the National Academy of Sciences·DateJan 25, 2016

Using nanoparticles to combat arteriosclerosis

A team of researchers developed a method for guiding replacement cells to diseased vascular segments using nanoparticles, which demonstrated promising results in mice. The fresh cells exert their curative effect in these segments by producing nitric oxide and regulating blood vessel expansion.

SourceUniversity of Bonn·JournalACS Nano·DateJan 6, 2016

New insights into the creation of heavy elements

A new method using supercomputers simulates the scattering of helium nuclei inside stars, shedding light on the formation of heavier elements. By reducing computational effort, scientists can now model complex processes involving more particles, bringing them closer to understanding the 'Holy Grail of astrophysics': oxygen creation.

SourceUniversity of Bonn·JournalNature·DateDec 2, 2015

Fossilized bees were finicky pollen collectors

A study found that fossilized bees from 50 million years ago were finicky about the pollen they fed their larvae, always collecting it from the same plants. The bees also ate a wide variety of things on their own flights, showing they didn't waste time searching for specific food sources.

SourceUniversity of Bonn·JournalCurrent Biology·DateNov 12, 2015

The hepatitis A virus is of animal origin

A large-scale study reveals the hepatitis A virus is likely of animal origin, with viruses from small mammals showing similarities to the human virus. The discovery offers new perspectives for risk assessments and may hint at a distant ancestry in primordial insect viruses.

SourceUniversity of Bonn·JournalProceedings of the National Academy of Sciences·DateNov 3, 2015

Researchers discover an epilepsy switch

A team of researchers has decoded a signaling pathway involved in the onset of seizure disorders, discovering that a central switch called MTF1 plays a key role. By inhibiting this switch, they were able to reduce seizures in epileptic mice, offering new potential for diagnosis and treatment.

SourceUniversity of Bonn·JournalNature Communications·DateOct 26, 2015

Plant pest reprograms the roots

Researchers discover nematodes produce plant hormone cytokinin to stimulate root cell growth and create a nurse cell system, essential for the parasite's survival. This discovery opens new avenues in plant breeding to develop resistance against cyst nematode pests.

SourceUniversity of Bonn·JournalProceedings of the National Academy of Sciences·DateSep 29, 2015

Blacklists protect the rainforest

The University of Bonn study found that Brazil's 'blacklisting' policy reduced Amazon forest loss by 26% per year. The researchers used data from 2008 to 2012 and compared listed communities with comparable non-listed communities.

SourceUniversity of Bonn·JournalPLOS ONE·DateSep 24, 2015

The Achilles' heel of HI virus

Scientists have found that the cGAS sensor can detect single-stranded DNA, including guanosines, which triggers a strong immune response. The HI virus has evolved to eliminate guanosines from its genetic material, partially avoiding detection by the cell.

SourceUniversity of Bonn·JournalNature Immunology·DateSep 8, 2015

Success combating multi-resistant bacteria in stables

Researchers at the University of Bonn successfully eliminated multi-resistant bacteria from a pig stable using radical hygiene measures, including frequent hand washing and quarantine. While MRSA was not eradicated, overall health improvement led to reduced antibiotic use, highlighting potential applications for hospitals

SourceUniversity of Bonn·JournalApplied and Environmental Microbiology·DateSep 7, 2015

Immune system: Help for killer cells

Scientists discovered that helper T cells boost killer cell reproduction and provide memory, enabling them to remember previous infections. This understanding could lead to the development of new vaccines that activate killer cells with harmless fragments of disease pathogens.

SourceUniversity of Bonn·JournalCell·DateAug 21, 2015

Researchers reconstruct dinosaur tracks

Researchers reconstructed dinosaur tracks at a 154-million-year-old quarry site, suggesting carnivorous dinosaurs hunted herbivorous island-dwelling dinosaurs. The digital model reveals that the predators could have immigrated via a land bridge as sea levels dropped.

SourceUniversity of Bonn·JournalPalaeontologia Electronica·DateJun 23, 2015

Getting children to embrace healthy food

A study published in Frontiers in Psychology found that primary school children preferred snacks with enticing packaging designs over those with health information or standard labels. The researchers used a handgrip dynamometer to measure the children's motivation and taste test to determine their preferences.

SourceUniversity of Bonn·JournalFrontiers in Psychology·DateJun 23, 2015

Researchers discover two new groups of viruses

Scientists at the University of Bonn discovered two new groups of viruses, Jonchet and Ferak, which are believed to have originated from insect viruses. The researchers found that these viruses are phylogenetically independent and do not multiply above 32 degrees Celsius, making human infection unlikely.

SourceUniversity of Bonn·JournalProceedings of the National Academy of Sciences·DateJun 2, 2015

What is more rewarding: A soccer goal or prize money?

A study by researchers at the University of Bonn found that brain activity in soccer players is similar when scoring a goal or winning money. Players with more egotistical personalities showed increased activity in learning and reflection regions when goals were scored after passing, not after taking the shot.

SourceUniversity of Bonn·JournalPLOS ONE·DateApr 15, 2015

Alcohol study yields surprising results

Researchers found that alcohol addiction is associated with a significantly increased risk of mortality in general hospitals, with patients dying an average of 7.6 years earlier than non-addicted patients. The study also identified 27 comorbid physical illnesses more frequently occurring in patients with alcohol addiction.

SourceUniversity of Bonn·JournalEuropean Psychiatry·DateApr 2, 2015

Next important step toward a quantum computer

Researchers from the University of Bonn and Cambridge successfully linked two different quantum systems, quantum dots and ions, to work together as a team. This hybrid system combines the strengths of both components, enabling faster calculations and improved memory storage.

SourceUniversity of Bonn·JournalPhysical Review Letters·DateMar 30, 2015

Fatal uncoupling in the epileptic brain

Researchers at the University of Bonn have discovered a new cause of temporal lobe epilepsy: astrocyte uncoupling. This leads to hyperexcitability of neurons and epileptic seizures. The study suggests that inflammation plays a role in uncoupling astrocytes, which can be reversed at an early stage.

SourceUniversity of Bonn·JournalBrain·DateMar 18, 2015

Gene leads to malformation of the urinary tract

A study published in PLOS Genetics has identified a gene, ISL1, associated with classic bladder exstrophy, a rare congenital anomaly of the urinary tract. The discovery is significant for understanding the disease's development and may lead to preventive measures during pregnancy.

SourceUniversity of Bonn·JournalPLOS Genetics·DateMar 12, 2015

Traffic light food labels strengthen self-control

Researchers at the University of Bonn found that traffic light labels are more effective in helping consumers resist high-calorie foods than traditional nutrition labels. The study participants were willing to pay significantly more for healthy products with green labels and less for unhealthy products with red labels.

SourceUniversity of Bonn·JournalObesity·DateMar 9, 2015

Dragnet for epilepsy genes

An international team of scientists identified sestrin-3 as a key regulator of gene networks in human epilepsy. Inhibiting sestrin-3 reduced seizures in animal models. The discovery offers promising starting points for new treatments, potentially avoiding drug resistance.

SourceUniversity of Bonn·JournalNature Communications·DateJan 23, 2015

Atoms can be in 2 places at the same time

Researchers at the University of Bonn have shown that cesium atoms can indeed take two paths at the same time, contradicting the macro-realistic view. The team's experiment uses optical tweezers to manipulate a single Caesium atom and measures its final position indirectly.

SourceUniversity of Bonn·JournalPhysical Review X·DateJan 20, 2015

Two or one splashing? It's different!

Researchers at the University of Bonn have successfully observed the interaction of exactly two atoms in a light cage, contradicting the assumption that two atoms would behave differently from a single atom. The experiment reveals that backaction suppresses high light waves, limiting the emergence of photons.

SourceUniversity of Bonn·JournalPhysical Review Letters·DateJan 15, 2015

A 'GPS' for molecules

Scientists create a molecular 'GPS' to precisely locate metal ions in enzymes, which play key roles in metabolism and synthesis. This innovation uses spin-labeled amino acids to track metal ion positions, enabling better understanding of biochemical reactions.

SourceUniversity of Bonn·JournalAngewandte Chemie·DateDec 19, 2014

Does your boss find you proactive ... or pushy?

Employees who take personal initiative but lack social acumen may be seen as troublemakers. A study found that proactive behavior is only beneficial if combined with social skills and sensitivity to favorable opportunities. Employers are looking for employees with both personal initiative and political skill.

SourceUniversity of Bonn·JournalJournal of Management·DateDec 3, 2014

It pays to have an eye for emotions

Researchers found that people with strong emotion recognition skills are perceived as more socially and politically skilled by colleagues and supervisors. They also earn significantly higher incomes. The study controlled for various factors affecting employee income and replicated its findings in a second study.

SourceUniversity of Bonn·JournalJournal of Organizational Behavior·DateNov 19, 2014

Climate capers of the past 600,000 years

The Lake Van drilling project provides a unique 600,000-year archive of climate fluctuations and natural hazards, including six cycles of warm and cold periods. The analysis reveals the region's high risk for earthquakes and volcanic eruptions.

SourceUniversity of Bonn·JournalQuaternary Science Reviews·DateNov 17, 2014

Oxytocin helps to better overcome fear

Researchers found that oxytocin facilitates extinction of conditioned fear in humans by reducing activity in the amygdala and increasing stimulation in fear-inhibiting regions. This basic research could lead to new treatments for anxiety disorders.

SourceUniversity of Bonn·JournalBiological Psychiatry·DateNov 13, 2014

Seeing dinosaur feathers in a new light

Dinosaurs had highly developed color vision, including the ability to see ultraviolet light, which likely contributed to the evolution of feathers. This discovery sheds new light on the origin of feathers and their role in dinosaur communication and mating.

SourceUniversity of Bonn·JournalScience·DateOct 30, 2014

Evolution of competitiveness

A study published in Nature Communications reveals that the evolution of competitiveness tends to diversify, with some individuals avoiding competition and others investing heavily. This divergence can lead to population extinction if external pressures fuel an 'arm's race' towards higher competitiveness.

SourceUniversity of Bonn·JournalNature Communications·DateOct 29, 2014

Cause of aging remains elusive

A recent study aimed to determine the role of free radicals in aging, but was refuted due to limitations with the measurement tool used. The researchers found that changes in pH levels inside mitochondria, rather than free radical release, were responsible for the signals detected by the probe.

SourceUniversity of Bonn·JournalNature·DateOct 22, 2014