Lab tests have found that silver compounds are as toxic to cancer cells as platinum-based drug Cisplatin, but may be less toxic to healthy human cells. Researchers hope to develop next-generation chemotherapy drugs using these findings.
Researchers analyzed genetic data to find clues about human migration over 60,000 years ago. They found evidence for an ancient ancestry within Arabia, suggesting it was the first staging-post in the spread of modern humans around the world.
A study by the University of Leeds found that older adults tend to stay in the middle lane while driving, an adaptive strategy that helps them stay safe. This tendency is linked to their reduced motor skills due to aging.
A new study published in The Lancet found that MRI scans are more accurate than SPECT tests in detecting coronary heart disease. MRI scans also do not use ionizing radiation, potentially reducing exposure for patients and healthcare professionals.
The study found an enzyme called 3D which forms fibrous structures during viral replication. A molecule to prevent this formation has been identified, providing a new avenue for exploration and potentially leading to a treatment for foot-and-mouth disease.
A study of over 60,000 individual fig flowers found that male pollinator fig wasps work together to chew escape tunnels for their females, increasing escape rates. In contrast, non-pollinating parasitic fig wasps, which are driven by aggression, fail to cooperate and have lower success rates.
Researchers have discovered a new muscle repair gene, MEGF10, which plays a crucial role in the fusion process of satellite cells. The findings provide accurate genetic testing and diagnosis for devastating conditions affecting muscle function, enabling hope for families affected by progressive muscle disease.
The Toxoplasma parasite affects dopamine production in infected brain cells, leading to increased dopamine levels and changes in behavior. This discovery may provide new insights into treating human neurological disorders such as schizophrenia, ADHD, and Parkinson's disease.
A new study by the University of Leeds reveals that major roads have a detrimental impact on bat populations, reducing activity and diversity. The research shows a strong correlation between distance from the road and bat activity, highlighting the need for effective mitigation measures to protect these protected species.
Researchers at the University of Leeds have discovered that leg muscle dysfunction is related to the severity of symptoms in heart failure patients. Daily activity in these patients can be limited by impaired leg muscles, not just a failing heart.
Researchers have identified two new drugs that may be effective in treating bipolar disorder, a condition characterized by mood swings between mania and depression. The drugs target the NKA enzyme and ERK protein, which are abnormally active in people with bipolar disorder.
A study by University of Leeds ecologists reveals that over 80% of ant species found in pristine forests were also present in logged areas. This finding has implications for forest conservation, suggesting that areas previously thought to have little value can still support diverse communities.
A novel system combines eye-tracking technology with CAD tools to recover intuitive design elements suppressed by digital technologies. The 'Designing with Vision' system allows designers to work fluidly with machines, combining human ingenuity and machine-based digital technology.
A new study shows that hospital heart attack death rates are improving, but elderly patients (85+) continue to lack access to specialist care, including emergency coronary angioplasty and vital heart medicines. This highlights the need for improved age-sensitive care to address inequalities in heart health.
A team of researchers has identified a way for the brain to protect itself when its energy supply is running low. The brain uses a protein called AMPK to reduce the firing frequency of electrical impulses, conserving energy. This discovery could lead to new treatments for patients at risk of stroke.
Researchers discovered three new DNA faults linked to melanoma, which are not related to hair, skin, or eye color. The genes, MX2, ATM, and CASP8, increase the risk of developing melanoma by 30 percent, particularly in people with two copies of these gene faults.
Researchers have found a rise in male breast cancer cases over the past two decades, despite low awareness. The study highlights the need for better information, treatment, and emotional support for men affected by the disease.
Researchers at the University of Leeds found that people with fair skin are more likely to have sub-optimal vitamin D levels. The study suggests that these individuals may need vitamin D supplements to maintain optimal health levels, particularly in areas with limited sunlight.
Researchers at the University of Leeds and Durham University have developed a high-tech 'recipe book' to create new plastics with specific properties. The breakthrough will increase recycling abilities and save industries time, energy, and money.
Breast cancer researchers identify FGFR3 as a key protein responsible for tumor growth and resistance to hormone therapies. This discovery may lead to the development of novel drugs targeting this protein to treat recurrent breast cancers.
A species of mosquito capable of transmitting West Nile virus has been found on Galapagos Islands, posing a significant risk to the archipelago's unique wildlife. Strict insect control measures and further research are recommended to prevent the disease from reaching the islands.
University of Leeds researchers used DNA sequencing techniques to identify a genetic defect in peroxidasin, which causes congenital cataract, corneal opacity, and developmental glaucoma. The discovery may lead to new treatments for adults and children with this form of inherited blindness.
Researchers at the University of Leeds have identified an antibiotic that can prevent the formation of amyloid fibrils in proteins. The discovery could lead to new treatments for diseases such as Alzheimer's, Parkinson's, and Type II diabetes.
Researchers at the University of Leeds have developed a peptide-based fluid that reverses tooth decay by stimulating regeneration of damaged tooth tissue. The treatment is applied directly to the affected area, providing a natural and non-invasive solution to filling teeth without drilling.
A University of Leeds investigation found that many over-the-counter herbal remedies are missing crucial safety information, despite new EU regulations. The study evaluated 68 products from various stores and pharmacies, revealing 93% were unlicensed and lacking comprehensive warnings.
Leeds researchers investigate the effectiveness of pure Eicosapentaenoic Acid (EPA) in preventing the spread of bowel cancer to the liver. Previous studies have shown that EPA may prevent large bowel polyps, a precursor to colorectal cancer.
Researchers at the University of Leeds have discovered a powerful way to suppress hepatitis C by targeting different parts of the virus. Two prototype small molecule drugs, p7 inhibitors, attack the virus in distinct ways, suggesting they could be used together with 'direct-acting' drugs for more effective treatment.
Researchers found smaller osmolyte molecules are more effective at protecting protein structures than larger ones, which could lead to better storage techniques for human reproductive tissue used in IVF and other materials.
Researchers have developed a new cancer vaccine using a library of DNA that targets multiple tumor proteins, avoiding overreaction by the immune system. Early studies in mice show successful treatment results without severe side effects.
Researchers have found a link between methane production and levels of archaeol in the faeces of cows, sheep, and deer, offering a potential solution to quantify animal methane contributions. The discovery could enable more accurate assessments of global greenhouse gas emissions.
A PhD student at the University of Leeds has developed a predictive model that accurately maps plant communities over large areas using aerial photographs and data from maps. The method achieved an accuracy of up to 92%, comparable to traditional on-site surveys conducted by trained ecologists.
A new model suggests that heat flow at the core-mantle boundary varies depending on the structure of the overlying mantle, causing localized melting. This phenomenon is linked to plate tectonics and affects the Earth's magnetic field generation.
Scientists investigate how a virus affecting the Indian meal moth impacts its host populations in size, with potential to inform better pest management strategies. The research could lead to improved techniques for controlling invasive species and pests.
A new model of island ecology suggests that most unique island species should be common on their island, contradicting the common perception of rarity. The researchers used data from 35 islands and archipelagos to develop the model, which predicts how many individuals of each species can be expected to see in their natural habitat.
A worldwide trial is being conducted to assess the use of robotic-assisted keyhole surgery in removing bowel tumours. The study aims to evaluate whether this approach makes cancer less likely to come back and reduces complications for patients.
A five-year study found that traditional nursing care methods, such as compression bandages and support stockings, work just as well as ultrasound therapy in healing venous leg ulcers. Laughter may also play a role in improving blood flow and overall health for patients with these conditions.
Researchers found that tumors with defects in DNA repair systems are less likely to recur post-surgery, reducing the need for chemotherapy. The study suggests testing for defective DNA mismatch repair and KRAS gene mutations to guide treatment strategies.
Researchers from six UK universities are studying how daily radiation exposure damages graphite blocks in nuclear power reactors. The study aims to help nuclear utility companies plan for the future and improve manufacturing processes.
A new genetic study has found that the DNA of current Polynesians can be traced back to migrants from the Asian mainland who settled in islands close to New Guinea around 6,000 years ago. The research challenges previous theories on human migration, suggesting a 'voyaging corridor' between Southeast Asia and the Pacific
Researchers found two severe Amazon droughts in 5 years have caused widespread and severe impacts on the region's rainforests. The carbon impact of these droughts may exceed previous estimates, potentially offsetting the Amazon's ability to absorb CO2 from the atmosphere.
New research suggests that hotter summers may slow down Greenland ice flow, contrary to previous fears. The internal drainage system of the ice sheet adapts to more melt-water, reducing ice speeds.
Researchers at the University of Leeds have uncovered the first misfold that triggers the formation of amyloid fibres, a critical step in understanding these disease-causing structures. This discovery offers new targets for therapies and may shed light on other protein-related diseases.
A team of British scientists are heading to the Antarctic Peninsula to collect rock samples and analyze their mineralogy, geochemistry, and isotopic character to determine how glaciers and ice sheets behaved in past climates. They aim to predict how these natural systems will react in years to come if temperatures continue to rise.
The study found that torrefying plant matter can transform it into a dry, energy-rich fuel that is cheaper and easier to transport. This process could potentially replace coal in power stations and provide a secure energy supply for the future while being sustainable on all levels.
A new type of vaccine is being developed that can trick the body into developing immunity against polio, with no risk of causing or spreading the disease. The replica virus particle will be designed to look and behave like the real virus but contain no genetic material.
The ImREAL project aims to create a simulated learning environment that responds to users' behavior and adapts accordingly. Researchers will develop intelligent tools to encourage trainees to detect subtle differences in communication and social cues across cultures.
A recent study has found that media coverage on HIV/AIDS in developed countries has decreased by over 70% since the 1990s. Meanwhile, attention to climate change has increased significantly, potentially diverting resources away from addressing socioeconomic issues like malaria and poverty.
Researchers at the University of Leeds have successfully created artificial spin ice, a state-of-the-art nanomaterial that has been difficult to produce in the past. By achieving thermal equilibrium, they can now study the precise configuration of magnetic monopoles and their potential applications in magnetricity.
Researchers at the University of Leeds and Manchester are conducting a £1.5 million project to inform sustainable urban transport planning by 2050. The STEP-CHANGE project will gather data on household travel behavior and analyze it with historical records to develop new tools for sustainability.
A new study reveals that APP695 is the primary source of amyloid-beta peptide, a toxic compound contributing to Alzheimer's disease. This discovery enables researchers to target their work more precisely, potentially leading to a better understanding and treatment of the disease.