Research published in The BMJ found that a cross-government strategy reduced health inequalities in England, but current policies are potentially reversing these gains due to austerity measures.
A new study published in Thorax found that smokers who undergo a low-dose CT scan of their lungs are more likely to quit smoking. The UK Lung Cancer Screening trial involved 4,055 participants and showed a 15% success rate in quitting after two years.
Researchers found that using newer dosing methods can minimize harmful effects while maximizing benefits in children with varying body mass indices. The study also suggests cost savings for the NHS.
Researchers at the University of Liverpool have developed a novel approach to treating chronic myeloid leukemia (CML), which safely increases treatment success and reduces negative side effects. The study, led by Professor Richard Clark, shows that CML patients with stable responses to treatment can reduce their medication dosage befor...
A new study has identified 18 genetic variations associated with lung cancer risk and 10 new gene variations. The research, conducted by an international team, used a special research platform called OncoArray to gather genotype data from different studies worldwide.
Research from the University of Liverpool reveals a strong association between childhood obesity and hip diseases, particularly Slipped Capital Femoral Epiphysis (SCFE). Obese children are at highest risk of developing SCFE, which can cause significant pain and lead to hip replacement in adolescence or early adulthood.
A new study published in The Lancet found that oral misoprostol tablets were more effective than Foley catheter induction in reducing need for caesarean section and increasing vaginal birth rates. Women who received oral misoprostol tablets also reported higher satisfaction rates with the outcome.
A recent study by the ENIGMA Project found that many chefs engage in risky behaviors such as serving undercooked meat, returning to work after illness, and failing to wash hands. The researchers used a dice-rolling technique to gather data, which revealed surprising findings about food safety practices in UK kitchens.
Researchers at the University of Liverpool have developed a computer-guided strategy that led to the discovery of two new materials in the laboratory. The algorithm uses chemical understanding of known materials to suggest new combinations of atoms, resulting in stable and synthesizable materials.
Cyanobacteria's protein machines, called carboxysomes, were biochemically purified and visualized using advanced microscopes. They were found to be softer and structurally flexible than previously thought, with implications for designing new nanomaterials and nano-bioreactors.
A new study suggests that implementing targeted food policies, such as subsidies for fruit and vegetables and taxes on sugar sweetened drinks, could avert hundreds of thousands of deaths from cardiovascular disease in the US. These economic incentives have been successful in improving dietary choices in the past.
Researchers used citizen scientists wearing boot socks on walks to find that slightly less than half of the socks were positive for Campylobacter, a common cause of diarrheal disease. The study suggests seasonal patterns and links to environmental factors, which could lead to interventions to reduce disease risk.
Physicists from the University of Liverpool have made a significant breakthrough in probing the 'dark content' of the universe using a novel experiment based on quantum interferometry. The experiment relies on ultra-cold atoms and could have far-reaching applications in navigation, gravity scanning, and understanding dark energy.
A new study from the University of Liverpool has identified common 'cell messages' that can help diagnose osteoarthritis in both humans and rats. The research also found that these messages are strongly associated with diseased cartilage, suggesting a potential breakthrough in early diagnosis and personalized treatment for OA.
Researchers found that around 15% of Ebola survivors have distinctive retinal scars, which appear specific to the disease but spare vision. The study also suggests that aqueous fluid analysis can help diagnose Ebola eye disease and enable access to cataract surgery for affected survivors
A new study has identified a protein called high mobility group box-1 (HMGB1) that may help patients with epilepsy respond more positively to drug therapies. The research found that HMGB1 isoforms can predict how an epilepsy patient's seizures will respond to anti-inflammatory drugs.
Research from the University of Liverpool found that female fashion mannequin body sizes are representative of severely underweight women, promoting unrealistic body ideals. The study suggests that altering mannequin size can help reduce emphasis on extreme thinness and challenge unhealthy beauty standards.
A clinical trial has discovered a drug combination that significantly reduces eye inflammation in children with Juvenile Idiopathic Arthritis (JIA). The therapy, Adalimumab plus Methotrexate, showed a 75% reduction in eye inflammation and prevented treatment failure.
Researchers have found that pain relief medication can ease the discomfort of zebrafish larvae, offering a potential replacement for adult fish used in scientific research. This breakthrough reduces animal suffering and paves the way for more humane testing methods.
Researchers have received £850,000 funding from NIHR to further develop the PPH Butterfly, a device that can stop bleeding and diagnose its source during childbirth. The device has already shown promise in treating postpartum hemorrhage (PPH), which affects 40,000 British women annually.
A team of researchers has identified the cause of a rare genetic disorder known as dystonia, which affects 70,000 people in the UK. The study found that mutations in the hippocalcin gene lead to overactivation of specific calcium channels, causing abnormal neuronal signaling and movement disorders.
Researchers are investigating whether seabirds use infrasound for navigation as they travel millions of kilometres across the ocean. The study aims to shed light on one of nature's unsolved questions and uncover how birds find their way year after year.
Researchers found that antibody production plays a limited role in clearing intestinal infection, and the immune response matures too slowly to fight off the bug within six weeks of age. Vaccines focusing on cell-mediated immunity or speeding up antibody production may offer promising solutions to controlling Campylobacter.
Researchers aim to understand Earth's internal evolution through palaeomagnetism, shedding light on the role of the deep mantle in plate tectonics and the planet's magnetic field. The project seeks to answer questions about Earth's geological lifespan and the conditions that shape its surface.
A new research center, Centre for Antimicrobial Pharmacodynamics (CAP), will be established at the University of Liverpool to accelerate the development of new antibiotics. The facility will provide access to pharmacodynamics research expertise, facilities, and training, addressing a significant gap in UK capability.
A study by the University of Liverpool found that providing a judicial warning when presenting transcript and video evidence to jurors improves their assessment of witness reliability. The research suggests that warnings are necessary in some cases, such as when video evidence is presented alone, and can help jurors consider the credib...
Scientists at the University of Liverpool have shown that phage therapy can kill drug-resistant strains of Pseudomonas aeruginosa, a common cause of chronic lung infections in Cystic Fibrosis patients. The study suggests that phage therapy could be a valuable addition to treatment options for these hard-to-treat infections.
A new study published in the BMJ Journal for Medical Humanities found that shared reading can be a useful therapy for chronic pain sufferers. The study compared shared reading to cognitive behavioral therapy (CBT) and found that shared reading provided a more comprehensive approach to managing emotional pain.
A University of Liverpool-led trial has successfully used nanotechnology to improve drug therapies for HIV patients, achieving a 50% dose reduction while maintaining therapeutic exposure. The trial's results have the potential to revolutionize HIV treatment, making it safer, more affordable and accessible to resource-limited countries.
A three-year trial by the University of Liverpool found that liraglutide 3.0 mg reduces type 2 diabetes risk by 80% in individuals with obesity and prediabetes. Participants experienced greater sustained weight loss compared to a placebo.
Children who move into poverty are more likely to suffer from social, emotional and behavioural problems than those who remain out of poverty. The study found that this is due in part to the adverse effect of poverty on mothers' mental health, which partially explains the negative impact on children's mental health.
Current UK salt reduction policies have failed to reduce existing inequalities in salt consumption, cardiovascular disease, and gastric cancer burdens. The study suggests that future legislative policies could further reduce socioeconomic inequalities in these conditions.
The University of Liverpool is coordinating a £14m European research project, TransQST, to improve drug safety by leveraging public and private data. The project aims to develop novel computational models to address off-target reactions and minimize harm from adverse drug reactions.
A UK-led clinical trial has successfully prolonged survival for pancreatic cancer patients by at least five years using a combination of chemotherapy drugs. The study found that patients who received this treatment had a 29% five-year survival rate compared to 16% for those on standard treatment.
Scientists have identified a 'molecular barcode' in blood samples from Ebola patients that can predict survival or death. The analysis provides data on the underlying causes of Ebola virus infection and suggests a potential diagnostic tool to guide treatment strategies.
Researchers aim to overcome traditional antenna limitations with liquid materials, enabling flexible and compact devices. The project will test liquids for stability and frequency transmission across various temperatures.
Researchers analyzed brushstrokes of famous artists' paintings for fractal patterns, detecting changes linked to neurodegenerative disorders. The study suggests a potential new method for identifying Alzheimer's disease in its early stages.
A new epidemiological model reveals that climate change and the 'Godzilla' El Niño of 2015 fueled the Zika outbreak in South America. The researchers predict a potential seasonal transmission risk for Zika virus in southern US, China, and Europe during summer.
A stem cell-based treatment, known as the Cell Bandage, has been trialled in humans and shown to repair damaged meniscus tissue, restoring full knee function. The trial received positive results, with three out of five patients retaining an intact meniscus after 24 months.
A University of Liverpool study found that reducing the dose of leukemia drug tyrosine kinase inhibitors (TKI) can safely reduce side effects in patients with chronic myeloid leukemia. Patients who achieved stable molecular remission levels showed no evidence of leukaemia rebound after cutting their TKI dose, with some reporting signif...
Researchers have identified protein p63 as crucial for triggering 'cell-suicide' in eye cancer cells, providing a breakthrough for metastatic uveal melanoma treatment. The discovery may lead to novel therapeutic strategies by targeting this protein in combination with other genes.
Researchers from University of Liverpool are leading a multinational consortium to reduce mother-to-child transmission of HIV in developing countries. The DolPHIN-2 project uses a new drug Dolutegravir to rapidly reduce HIV levels, potentially preventing infant transmission and saving lives.
A University of Liverpool research team has discovered that tumour-associated macrophages and fibroblasts secrete insulin-like growth factors, which activate a survival signalling pathway in pancreatic cancer cells, making them resistant to chemotherapy. This mechanism is found in 72% of patients, paving the way for new therapeutic tar...
Researchers identified preoperative abnormalities of two temporal lobe white matter tracts that are not included in standardised temporal lobe surgery in patients who had postoperative seizures. These findings suggest new insights into predicting postoperative seizure outcome using preoperative imaging technology.
Researchers developed a novel water dispersible nanotherapy for paediatric HIV patients, removing the need for high ethanol concentrations. The new approach has the potential to overcome challenges with current antiretroviral therapy, including administration of high doses and urgent need for better formulations.
A two-and-a-half-year study found that children who survived cerebral malaria had indistinguishable cognitive development compared to healthy peers, despite poor overall performance. The results highlight the need to investigate additional factors such as nutrition and environmental conditions.
Researchers developed a new international guideline to standardize clinical trial results reporting, increasing the efficiency and value of global research. The COS-STAR statement provides a checklist of 18 essential items for transparent and complete reporting in Core Outcome Set studies.
A University of Liverpool study found that ant colour and size are strongly influenced by their environment, with larger bodied ectotherms with dark colouration thriving in cold places. The study also revealed that ants adapt to changing temperatures by shifting from darker to lighter colours and smaller body sizes.
A recent study by the University of Liverpool has found that a potentially fatal tick-borne disease called canine babesiosis in the UK appears to be under control. The study analyzed data from 2015 and found a low background level of Babesia infection in the UK, with most cases linked to overseas travel.
Wildlife-friendly farming schemes have been shown to boost UK moth populations by 40% on wide grass margins and up to 40% for specialized chalk grassland moths when habitats are created close to existing chalk grasslands. These findings support the conservation benefits of agri-environment schemes.