A study by Drs. Sapieha and Mallette reveals a program of accelerated aging in the retina, leading to cellular senescence and production of factors that contribute to blinding disease. Interfering with this process using novel drugs improves blood vessel regeneration and reduces retinal damage.
A new study found that even low physical fitness levels can reduce most cardiovascular risk factors. Researchers analyzed 205 men and 44 women with heart disease, finding that normal fitness levels were sufficient to prevent five of the eight risk factors, including depression and obesity.
Researchers found that African Americans have a stronger immune response to bacterial infections compared to Europeans, partly due to genetic differences. This response is linked to reduced susceptibility to autoimmune inflammatory diseases such as Crohn's disease and tuberculosis.
A team of researchers led by Dr. Marie Kmita discovered that the transition from fin to limb was not accomplished overnight and identified a key difference in gene regulation between fish and mice. By reproducing the fish-type regulation, mice developed up to seven digits per paw, revealing the significance of this difference.
A new study published in The Lancet Respiratory Medicine found that respiratory viral detection, not child's age, explains the high rate of hospitalization for asthma attacks in children under six. The study confirms the overall effectiveness of standard treatment when adjusted to the severity of the attack.
A study published in the American Journal of Obstetrics and Gynecology found that nicotine patches and Zyban are effective in helping pregnant women quit smoking, with success rates of 80% and 60%, respectively. The use of these products also reduces the risk of premature birth and low birth weight.
A team of scientists has discovered that two genes associated with Parkinson's disease are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease. The study found that proteins produced by these genes can prevent cells from being detected and attacked by the immune system.
Researchers found that impulsive children raised in non-coercive environments tend to drink less alcohol than their peers, as they thrive under proper care and attention. High impulsivity at age 6 was associated with lower alcohol use at age 15 when maternal coercive practices were infrequent.
Researchers introduce a novel method for labelling individual cells using photobleaching, enabling precise targeting of unique cells in vast populations. This technology has the potential to transform our understanding of diseases by allowing researchers to study specific cells responsible for disease progression.
Researchers at University of Montreal developed programmable DNA thermometers that can measure temperature at the nanoscale. The smallest thermometer is 5 nm-wide and produces an easily detectable signal as a function of temperature.
Research reveals smoking addiction in schizophrenia is associated with higher neuronal activation of the ventro-medial prefrontal cortex, leading to low smoking cessation rates and increased health risks.
Researchers found that concussions in young children can lead to a decline in their social interactions with parents. The study aimed to assess the quality of parent-child relationships six months after injury.
Research by Dr. Sven Joubert reveals that Alzheimer's disease affects holistic face perception, leading to difficulties in recognizing faces of family members or celebrities. This impairment is observed even in the early stages of the disease, highlighting potential strategies for patients to recognize their loved ones for longer.
A recent study by University of Montreal researchers has discovered a common genetic defect in beta cells that may lead to the loss of insulin production in both type 1 and type 2 diabetics. The findings suggest that genetics play a critical role in beta cell survival, with fragile cells being more prone to damage and disease.
Researchers found that photoreceptors use both glucose and lipids as fuel substrates, debunking previous scientific beliefs about the cause of abnormal blood vessel growth leading to blindness. This discovery opens new therapeutic avenues for retinal diseases such as AMD.
A study of 1,040 Quebeckers found that nearly half were interested in at least one type of anomalous sexual behavior, with some behaviors more common than thought. The research suggests a distinction between paraphilic sexual behavior and disorders, and challenges the DSM-5's classification.
Research breakthrough reveals pancreatic tumours often lose miR-137 expression, triggering uncontrolled cell growth and cancer. Restoring normal miR-137 levels induces senescence and stops cells from spreading.
A new interactive tool reveals distinct climate opinion patterns across Canada's provinces and ridings, with significant variations in Alberta versus Quebec. Canadians broadly agree that Earth is warming, but regional differences and demographic factors influence opinions on emissions trading systems.
Researchers have identified a dozen FDA-approved drugs that reactivate tumour suppressor genes through an epigenetic mechanism, targeting intracellular calcium levels. These cardiac glycosides and antibiotics may rapidly become available for clinical validation and treatment of cancer patients.
A new therapeutic approach using autograft followed by allograft resulted in a record-breaking 41% cure rate and 60% relapse-free survival rate in patients with multiple myeloma. The study showed promising results with low mortality rates and high efficacy in subsequent treatments.
Researchers challenge Health Canada's black-box warnings on ADHD medications, citing epidemiological studies showing reduced youth suicide rates with increased medication use. The study suggests that ADHD medications may actually reduce the risk of suicide in adolescents, contradicting previous warnings.
Researchers have identified a new mechanism governing DNA repair in the presence of certain class of histone deacetylases. This discovery has implications for cancer treatment and could lead to optimization of clinical use of HDAC inhibitors.
Researchers found a 25-point IQ drop in carriers of the 16p11.2 gene deletion, even in individuals with normal IQ scores. The study quantified the additive effects of genetic mutations on cognition and behavior.
A longitudinal study found that exposure to violence in childhood is linked to increased symptoms of conduct disorder and antisocial personality in adolescence and adulthood. The MAOA gene was also identified as a key moderator of this relationship, with certain variants increasing the risk of aggressive behavior and partner violence.
Researchers discovered a previously unsuspected mechanism that activates innate immune defenses within hours of bacterial infection, triggering DNA methylation changes. The discovery sheds light on how the innate immune system remembers past attacks and provides new insights into vaccine development.
The Quebec law allows medical aid in dying only for people at end-of-life, with a prognosis of six months or less left to the physician's judgment. Vulnerable groups, such as those with depression, may be disproportionately affected by this restrictive approach.
Adolescents separated from their fathers experience increased stress and transient depression symptoms four to nine months following separation. However, these symptoms typically disappear over time. The study highlights the importance of informal support or therapy for young adults whose parents have recently separated.
A recent study published in JAMA Pediatrics has found that taking antidepressants during pregnancy significantly increases the risk of autism in children. The study analyzed data from over 145,000 pregnancies and found an 87% increased risk of autism when antidepressants were used during the second or third trimester.
A study by Professor Olivier Bauer found that Montreal's culinary heritage is influenced by Jewish cultural heritage, with bagels and smoked meat becoming iconic symbols of the city. The researcher notes that these foods have become popular among workers and tourists alike, despite their Jewish origins.
A study found that taking Truvada 'as needed' around periods of sexual activity reduced the risk of HIV transmission amongst men and transgender women at high-risk by 86%. The researchers suggest this approach can increase adherence to medication regimes, leading to improved prevention outcomes.
Democracy faces challenges from polarization and increasing inequalities, argues Charles Taylor. Michael J. Sandel warns of the corrosive effect of neoliberal ideology, which disengages citizens from public affairs. Rebuilding a shared civic life is also crucial, according to both thinkers.
Researchers at the University of Montreal have developed a new, non-invasive approach to detect concussions in young football players. The method uses a dual-task assessment and markerless motion capture system to establish a unique profile for each player in just seven minutes.
Researchers found that having over 300 Facebook friends increases cortisol levels in teens, while supportive behavior towards friends reduces stress. The study suggests that excessive social media use can lead to increased stress and potentially depression.
Researchers found that consumers of problem-focused self-help books present greater depressive symptoms, while growth-oriented book consumers show increased stress reactivity. Further research is needed to determine the cause of this observation.
A study by researchers at the University of Montreal found that preschoolers' working memory skills can predict their risk of dropping out of high school. Parents can help their children develop strong working memory skills through activities like pretend play, mindfulness, and limited screen time.
A comprehensive review of 135,000 pregnancies found that two most commonly prescribed macrolides have no adverse effects on child's physical development. The study used data from Quebec Pregnancy Cohort and failed to find any meaningful association between macrolide use and major congenital malformations.
Researchers from the University of Montreal found that singing calmed infants twice as long as talking, with an average duration of 9 minutes for songs and 4.5 minutes for baby talk. The study suggests that singing has emotion-regulatory properties that can help parents soothe their children.
A new study published in JAMA found that pregnant women with preeclampsia have a higher risk of delivering an infant with a congenital heart defect. The research examined hospital records of over 1.9 million mother and infant pairs, revealing significant association between the diseases.
Dr. Lefkowitz's research reveals that all GPCRs share the same structure, enabling the development of more effective and safer drugs for various pathologies including type 2 diabetes and obesity.
Trees grown in contaminated soil exhibit enhanced defense mechanisms against pests, as genetic information from other organisms is expressed differently. This phenomenon enables trees to better fend off biotic stresses, potentially revolutionizing phytoremediation processes.
Advanced laser surgery and echocardiography predict fetal development and survival in complicated monochorionic twin pregnancies. Dr. Audibert presents results from 115 treated cases, exploring the usefulness of these techniques to improve outcomes.
Researchers at the University of Montreal found that humans can recognize familiar voices with nearly 100% accuracy, even in noisy environments. This surpasses current automatic speech recognition systems, which struggle to reach 99.9% accuracy.
A new virtual reality approach has been developed to improve the treatment of aortic aneurysms by providing more accurate visualization of the area needing treatment. The approach uses 3D images and simulations to predict the risk of rupture and optimize treatment options, including open surgery and endovascular grafting.
A new approach using DNA nanomachines can detect specific antibodies in five minutes, enabling rapid and affordable point-of-care diagnostics for infectious diseases like HIV. This technology promises to reduce healthcare costs and treatment initiation delays.
A new technique using human embryonic stem cells has been developed by Professor Gilbert Bernier, allowing for the production of light-sensitive retina cells. This breakthrough could lead to treatments for currently non-curable eye diseases like Stargardt disease and age-related macular degeneration.
A study by Professor Victor Boucher of the University of Montreal found that repeating aloud boosts verbal memory, especially when done in a context of communication. The research showed that repeating aloud to someone else increased information recall compared to repeating silently or in one's head.
A study by Professor Pascale Lehoux found that venture capitalists evaluate technologies based on their commercial potential rather than intrinsic value for healthcare systems. As a result, health technologies are often developed to meet investors' short-term financial return, rather than addressing pressing healthcare needs.
Researchers found that shielding parenteral nutrition from light significantly decreases oxidative stress and cell damage in premature infants, improving their survival rates. The study's findings suggest a potential solution for reducing mortality rates in preterm infants born between 26-31 weeks of gestation.
A study by researchers at the University of Montreal found that women's brains react more strongly to negative images than men's, possibly due to greater emotional sensitivity. The connection between the amygdala and prefrontal cortex was stronger in men, suggesting a more analytical approach to negative emotions.
Researchers at the University of Montreal developed rapid and inexpensive medical diagnostic tests using DNA molecules. The new technology detects protein markers linked to various diseases and can be used to build point-of-care devices for quick medical diagnosis, potentially impacting global health.