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University of Southern California


Heart data unlocks sleep secrets

Researchers at USC developed an approach that matches polysomnography using a single-lead echocardiogram, allowing anyone to create their own low-cost, DIY sleep-tracking device. The software significantly outperformed other EEG-less models and assesses sleep stages at the highest level.

SourceUniversity of Southern California·JournalComputers in Biology and Medicine·DateAug 19, 2024

USC study: Drug protects against air pollution-related Alzheimer’s signs in mice

A new USC study led by Caleb Finch shows how feeding mice the drug GSM-15606 provided protection against air pollution-related increases in proteins linked to Alzheimer's disease. The results indicate that GSM-15606 may one day have a role as a preventive measure against Alzheimer's in people living with air pollution.

SourceUniversity of Southern California·JournalAlzheimer s & Dementia·TypeExperimental study·DateAug 12, 2024

USC researchers develop AI model that predicts the accuracy of protein–DNA binding

A new AI model, Deep Predictor of Binding Specificity (DeepPBS), can accurately predict protein-DNA binding across different types of proteins. This tool allows for the prediction of binding specificity from protein-DNA complex structures, reducing the need for high-throughput sequencing or structural biology experiments.

SourceUniversity of Southern California·JournalNature Methods·TypeData/statistical analysis·DateAug 8, 2024

When it comes to butterflies, people prefer pretty ones. That’s a problem for scientists.

A new study reveals that data on popular community science platforms is biased towards easily identifiable and attractive species. Researchers found that iNaturalist's reliance on photos creates a personal bias, underreporting certain species and overreporting others.

SourceUniversity of Southern California·JournalFrontiers in Ecology and the Environment·TypeComputational simulation/modeling·DateJul 23, 2024

USC scientists use AI to predict a wildfire’s next move

Researchers at USC developed a new method to accurately predict wildfire spread using satellite data and artificial intelligence. The model offers a potential breakthrough in wildfire management and emergency response, providing more precise and timely data for firefighters and evacuation teams battling wildfires.

SourceUniversity of Southern California·JournalArtificial Intelligence for the Earth Systems·TypeComputational simulation/modeling·DateJul 22, 2024

States with the most restrictive abortion policies saw the biggest declines in use of birth control and emergency contraceptives after Dobbs decision

A new USC study found that states with the most restrictive abortion policies experienced significant declines in the use of birth control pills and emergency contraceptives. The analysis suggests that the Dobbs v. Jackson Women's Health Organization case has had wider ramifications for women's reproductive health than previously thought.

SourceUniversity of Southern California·JournalJAMA Network Open·TypeData/statistical analysis·DateJun 26, 2024

Discovery of vast sex differences in cellular activity has major implications for disease treatment

Researchers discovered extreme differences in mitochondrial gene activity between males and females, highlighting the need for sex-specific disease therapies. The study, published in the Proceedings of the National Academy of Sciences, found that male mitochondria exhibit more protein-coding genes than females.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJun 25, 2024

From wearables to swallowables: USC Engineering researchers create GPS-like smart pills with AI

Researchers from USC Viterbi School of Engineering have developed ingestible sensors that track gastrointestinal health in real-time. These 'smart pills' use AI and wearable technology to detect gases associated with gastritis and gastric cancers, offering a significant step forward in ingestible technology.

SourceUniversity of Southern California·JournalCell Reports Physical Science·TypeExperimental study·DateJun 12, 2024

Study: Integration of pharmacies with physician practices has little impact on cancer drug expenditures

Researchers found a slight increase in utilization of oral oncology drugs but no significant change in expenditures. The study also showed that integration did not improve medication adherence or reduce out-of-pocket costs for patients. Despite this, the shift towards oral cancer therapies may lead to changes in physician revenue.

SourceUniversity of Southern California·JournalJAMA Network Open·TypeObservational study·DateMay 23, 2024

Study finds extreme temperature swings hit minority, low-income communities hardest

A new study found that daily temperature variation has a disproportionate impact on marginalized groups, particularly Black and brown communities, with greater swings in temperature on average. The researchers used satellite data to analyze temperature patterns across the US, finding that densely populated regions with limited green sp...

SourceUniversity of Southern California·JournalPNAS Nexus·TypeData/statistical analysis·DateMay 21, 2024

Airborne technology developed at USC brings new hope to map shallow aquifers in Earth’s most arid deserts

A team of researchers at USC has developed an 'Airborne Sounding Radar for Desert Subsurface Exploration of Aquifers,' nicknamed 'Desert-SEA.' This technique uses low-frequency radar to map the top of shallow aquifers, allowing scientists to assess their sustainability without limitations associated with in-situ mapping. The technology...

SourceUniversity of Southern California·JournalIEEE Geoscience and Remote Sensing Magazine·DateMay 16, 2024

A new ‘rule of biology’ may have come to light, expanding insight into evolution and aging

Molecular biologist John Tower proposes a new 'rule of biology,' selectively advantageous instability (SAI), which suggests that some volatility in biological components provides an advantage to cells. SAI plays a key role in evolution, allowing for genetic diversity and adaptability, and may also contribute to aging.

SourceUniversity of Southern California·JournalFrontiers in Aging·TypeLiterature review·DateMay 16, 2024

USC study reveals racial disparities in diagnosis and drug use for dementia symptoms

White and Hispanic people are most likely to be diagnosed with behavioral symptoms of dementia, but also receive potentially harmful drugs. The study found substantial racial disparities in dementia diagnosis and treatment, with non-white patients being underdiagnosed for treatable symptoms.

SourceUniversity of Southern California·JournalJournal of Alzheimer’s Disease·TypeData/statistical analysis·DateMay 14, 2024

People with rare longevity mutation may also be protected from cardiovascular disease

A recent study found that individuals with a rare condition known as growth hormone receptor deficiency (GHRD) have normal or improved levels of cardiovascular disease risk factors compared to their relatives. This suggests that GHRD may actually protect against cardiovascular disease, contrary to previous speculation.

SourceUniversity of Southern California·JournalMed·TypeObservational study·DateApr 26, 2024

USC Schaeffer Center study finds few hospitals promoting potentially predatory medical payment products

A recent USC Schaeffer Center study found that fewer than one-in-ten hospitals promote interest-bearing medical payment products, with those promoting them being disproportionately non-profit hospitals. The study suggests regulators take a closer look at hospital financial conditions before enacting regulations.

SourceUniversity of Southern California·JournalJAMA Health Forum·TypeData/statistical analysis·DateMar 29, 2024

USC study: newly discovered beneficial mutation in mitochondrial DNA appears to help Alzheimer’s gene carriers live longer, stay sharper and represents a new direction in drug discovery

Researchers discovered a genetic mutation in humanin, a mitochondrial microprotein, that may help individuals with the APOE4 allele live longer and preserve cognitive function. The variant was found to reduce amyloid-beta buildup in the brains of mice engineered to express human APOE4.

SourceUniversity of Southern California·JournalAging Cell·DateMar 23, 2024

Landmark study shows that ‘transcendent’ thinking may grow teens’ brains over time

A landmark study found that adolescents who grapple with the bigger meaning of social situations experience greater brain growth. This type of thinking predicts stronger identity development and life satisfaction years later. Brain networks involved in effortful thinking and internal reflection coordinate to predict psychosocial outcomes.

SourceUniversity of Southern California·JournalScientific Reports·DateMar 18, 2024

This common medication could save half a million children’s lives each year. So why is it underprescribed?

A new study found that healthcare provider perceptions of patient preferences are the biggest barrier to prescribing oral rehydration salts (ORS), which costs only a few cents. Patients expressing a preference for ORS increased prescribing by 27 percentage points, making it an effective intervention.

SourceUniversity of Southern California·JournalScience·TypeRandomized controlled/clinical trial·DateFeb 8, 2024