Articles tagged with Biomedical Engineering
Researchers developed miniature solar panels to control cell alignment in 3D-printed biological tissue. By adjusting solar cell layout and intensity, they achieved desired shapes and correlated cell alignment with patterning.
Researchers will investigate how energy constraints shape neural computation, from molecules to circuits to behavior. The study aims to provide the first quantification of energy costs of computation across spatial scales, revealing how the brain optimizes computation within its energy budget.
A new book-sized robot, MAPLES, streamlines super-resolution image preparation by automating the washing process, reducing manual errors and increasing consistency. The system's high precision and throughput enable researchers to produce high-quality images with improved accuracy and reduced variability.
Researchers found that sensory nerves release signaling molecules that interact with bone cells and influence bone metabolism. Removing sensory nerves prevents normal recovery of bone mass after mechanical loading was restored. The study suggests that sensory nerves are essential for regulating bone homeostasis.
A University of Houston researcher is developing a light-based technology to analyze tiny particles in the blood for molecular signs of liver cancer. The approach aims to detect the disease at its earliest stages and improve treatment options.
Fateme Baneshi, Isabel Espejo Díaz, and Marta Lacuna Mohedano, three entrepreneurs from the UC3M Science Park, have been recognized as STEAM Role Models by APTE. They exemplify entrepreneurial drive in STEAM disciplines, with projects ranging from AI applications to biotechnology and engineering.
A study of 10,000 employees found that sit-stand desks increase active computer time by 43 minutes a day, resulting in 171 additional hours of work per year. This translates to a potential annual productivity gain of nearly $9,000 per employee.
A novel cell-sorting chip developed by researchers in Singapore and China uses a non-invasive, label-free method to sort cells. The system requires pre-focusing, cell sensing, and single-cell level manipulation, and can sort cells based on subtle functional electrical signatures.
Researchers develop advanced implant coating to counteract biological responses in diabetes patients, reducing inflammation and promoting tissue integration. The technology has potential to improve healthcare outcomes for millions living with diabetes.
Scientists at Tampere University develop a new approach to composite fillers, designing each particle's 3D geometry before printing, enabling tailored stiffness and mechanical behavior. The new method could lead to breakthroughs in soft robotics, biomedical materials, and tissue engineering.
The CT scans of Jeremy Bentham's head have provided valuable insights into his life and after-life, showing that he suffered from chronic toothache and a jaw riddled with arthritis. The scans also reveal further physiological factors, such as tissue structure and preservation choices, which were previously unknown.
Researchers review how AI enhances continuous glucose monitoring to enable predictive, personalized diabetes management, improving glycemic outcomes and prioritizing high-risk patients. Machine learning models forecast individualized responses to meals, enabling tailored dietary and physical activity guidance.
Alliance Clinical Trials is advancing early detection, improving treatments, and enhancing survivorship for lung cancer patients. The organization is conducting seven active clinical trials focused on prevention, early detection, treatment, and survivorship.
A new review proposes three complementary enhancement pathways to improve urban water ecological resilience, including measurable resilience targets, before–after evaluation frameworks, and equity-aware governance. Four interacting drivers shape UWER, generating nonlinear feedback and threshold effects.
A new AI and biological data-driven approach revolutionizes urban water safety by tracking behavioral and morphological changes in indicator organisms and metabolic biomarkers. The framework prioritizes potential risk factors, enabling actionable priorities for management and shifting from reactive cleanup to predictive resilience.
The UVA Biotech Innovation Fund will support the SPARK Innovative Medicines program, helping to accelerate promising discoveries into new treatments and cures. The fund will provide long-term support for researchers to overcome the critical gap between discovery and clinical application.
A putty-like electrode developed by McGill University researchers has shown promise in improving vocal rehabilitation for patients with voice disorders and upper airway diseases. The device, made of a soft, silicone-based putty, conducts electricity like a metal via tiny silver wires, recording clean signals from small neck muscles.
The review proposes an evidence framework to separate direct target engagement from downstream effects in plant-derived anti-inflammatory drug discovery. Plant-derived compounds exhibit pleiotropy, influencing multiple inflammatory pathways, but direct target binding and downstream effects are distinct.
Researchers have discovered alternative mechanisms for blood vessel growth that occur in the absence of VEGF-VEGFR2 signalling. This finding may help explain why tumors develop resistance to anti-angiogenic therapies and identify new therapeutic targets.
Researchers at Jeonbuk National University developed a breathable wearable patch using mulberry paper, combining 3D-printed microneedles for drug delivery and wireless uric acid sensing. The patch showed rapid wetting and promoted moisture transport, supporting sweat collection and analysis.
A team of engineers and surgeons from Johns Hopkins Medicine has developed a temporary implant that can monitor spinal cord injuries, providing real-time feedback to medical teams. The device, called Multimodal Ultrasound System for Injury Care (MUSIC), can track changes in blood flow and identify potential complications, aiming to imp...
Researchers developed a novel vaccination system for farmed fish using water-resistant, food-grade microneedles that can deliver vaccines without sedating fish or using needles. This approach aims to improve fish health and reduce labor intensity, stress, and costs for farmers.
Researchers developed a brain-inspired computing architecture that processes sparse events from EEG, reducing energy use and latency. The design achieved higher accuracy than comparison models on five public datasets, with significant improvements in efficiency and low power consumption.
Researchers are developing a blood test that can decipher the body's secret messages from a blood sample, potentially replacing biopsies. The test can detect diseases at an earlier stage and monitor treatment effectiveness more effectively.
Researchers develop transdermal bioreactor patch to reprogram patient's own cells to fight disease or repair tissue, with potential applications in melanoma, diabetes, and autoimmune diseases. The technology aims to make advanced cell therapies faster, less costly, and available to more patients.
Researchers developed DNA nanomachines that detect two ctDNA mutations simultaneously without DNA amplification, achieving improved sensitivity and specificity. The platform has potential for tracking treatment response and emerging resistance in cancer patients.
MIT researchers have developed a magnetic tracking system that can accurately track muscle movement using tiny magnetic beads implanted in the muscle. This system could enable people with certain types of amputations to control their prosthetic limbs more naturally. The system uses pairs of magnets implanted into muscles, which can be ...
Researchers at Stanford University have developed a non-invasive gene editing technique using ultrasound and light-emitting nanoparticles, enabling precise control over gene editing in specific locations of the brain and body. This breakthrough could lead to new treatments for neuropathic pain and other conditions, offering a more targ...
A comprehensive review introduces a novel framework for connecting cutting-edge deep learning technologies with core clinical tasks in pathology. The review highlights emerging trends and approaches that tackle the bottleneck of vast amounts of expertly annotated data, allowing AI models to learn from large, unlabeled datasets.
Researchers developed a long-acting protein-based therapeutic by fusing human erythropoietin to engineered albumin, showing a 5.7-day plasma half-life and improved mucosal barrier crossing. The fusion protein maintained therapeutic function and increased red blood cell production.
A new robotic enteroscope can inch through the hard-to-reach small intestine, making biopsies and drug delivery easier. The robot uses a snake-like locomotion strategy and textured coating to gain traction on the mucosal lining, allowing for automated evaluation and treatment of intestinal complications.
Researchers developed an AI model using retinal images to diagnose diabetic nephropathy and predict progression, avoiding kidney biopsies. The model achieved high accuracy and robust performance, showing great clinical value in kidney disease diagnosis and management.
Researchers have developed silk-based materials for tendon and tendon-bone regeneration, showcasing excellent biocompatibility and tunable mechanical properties. The materials, including hydrogels, sponges, and electrospun fibers, can mimic the native tendon architecture and guide tissue regeneration.
Mizzou researchers are studying how influenza spreads and how environmental conditions influence transmission. They aim to understand how infected people release the virus and what factors make some people less susceptible to infection.
A Chinese Neurosurgical Journal study found that linear accelerator-based radiosurgery reduced seizure frequency by 75.6% in patients with drug-resistant mesial temporal lobe epilepsy. However, the approach was associated with several adverse events, including visual field deficits and recent memory impairment.
The Hēlo Thrombectomy System, developed by a team of neurosurgeons and engineers at the University of Michigan, has been cleared by the FDA for removing lung clots in patients with chronic venous thromboembolism. The device uses a combination of suction and agitation to gently pull on the clot, stretch and thins it, and vacuums it out ...
A UT San Antonio College of Sciences researcher has developed a novel molecular smart probe that illuminates breast cancer cells during surgery, providing surgeons with cleaner margins and patients lower risk of recurrence. The probe targets proteins in the cells that fuel tumor growth and is paired with an FDA-approved drug to form a ...
Research finds that FGFR1 signaling helps organize bone-building material and cellular connections needed for newly embedded bone cells to survive. Disrupting this signaling can lead to osteocyte death and impaired bone formation.
A metalens photoacoustic microscope can switch focus with voltage, enabling deeper imaging of biological structures. The system achieves an axial imaging range of approximately 1.2 mm and high spatial resolutions for visualizing microscopic vascular structures.
Researchers identified a novel oncogenic mechanism involving DNA demethylation in hepatocellular carcinoma, promoting tumor formation without canonical driver gene mutations. Suppressing TET1 reduced tumor formation in mice, supporting the relevance of these findings in human liver disease data.
A Lehigh-led team is developing an AI platform called UniBrain to simplify brain imaging analysis, reducing the time and expertise required. The platform aims to unify image preprocessing and downstream brain network analysis, integrating information from multiple imaging modalities.
A research team developed a medical adhesive patch that attaches securely but can be removed with markedly reduced force when needed. The patch uses a shape memory polymer material that recovers its original geometry when heated, reducing the effective contact area at the skin-adhesive interface and allowing for gentle detachment.
Researchers have developed a triple-layered artificial nerve conduit embedded with living cells that steers nerve regrowth across deep gaps, achieving functional recovery in rats that rivals a natural graft. The bioprinted nerve 'railway tracks' guide regenerating tissue, promoting axon-guidance genes and restoring electrical impulses.
A new manufacturing method enables the creation of flexible devices that can crawl, move, and shield electromagnetic interference. The technique uses laser-induced selective metallization and magnetic liquid metal to form precise metallic patterns on complex 3D-printed polymer surfaces.
Researchers developed a bioactive, biodegradable, 3D-printable biomaterial from soybean waste, showing antioxidant and anti-inflammatory activity. The material's versatility enables the design of customisable devices for pain management during breastfeeding and post-operative recovery following breast cancer surgery.
Researchers at Mizzou discovered that tongue exercise can improve the activity of surviving neurons controlling tongue movement, helping them compensate as other neurons are lost. This finding offers hope for preserving quality of life for those with ALS and other motor neuron diseases.
A Johns Hopkins Medicine-led team will build an artificial intelligence model to identify protein misfolding for earlier disease detection and treatment. The goal is to generate tools and resources for clinicians and researchers to diagnose and intervene at earlier stages of neurodegenerative conditions.
Researchers at the University of Illinois Chicago have developed a 4D biofabrication technology using kirigami strategies to generate complex tissue forms. This approach enables the creation of tissue geometries with precise control over shape and curvature, potentially addressing a longstanding challenge in tissue engineering.
A new rapid test developed by Penn State researchers detects lower levels of antibodies to fight syphilis bacteria, potentially leading to earlier interventions. The test uses layered nanoparticles that accumulate and form a visible line for a positive result, improving detection in the early stages of the infection.
Researchers developed a framework to detect abnormal lung sounds in children using smartphones, achieving high accuracy and outperforming traditional methods. The framework can provide an assistive tool for home-based respiratory screening, improving remote clinic consultations and community healthcare.
A new system for wound analysis, developed by NJIT researcher Salam Daher, provides more precise measurements and improved tracking of wound healing. The system uses 3D scanning and digital modeling to capture changes in wound shape and size, offering a more complete view of healing progress.
Researchers developed a method to observe antibody interactions with cancer-related proteins on tiny vesicles, showing that protein presence doesn't guarantee accessibility to antibodies. This approach can distinguish between stable and fleeting interactions, providing a new way to investigate differences between individual cancer-deri...
Researchers designed a new lipid recipe that improves mRNA delivery precision, reducing liver accumulation and improving local expression. The new formulation, SM102M, showed strong local expression while sharply reducing liver expression in mice, and maintained delivery over repeated doses.
Heart failure alters the bone marrow, reducing protective cells that regulate inflammation, reports a study conducted at Science Tokyo. The bone marrow niche is found to play an important role in transmitting the effects of cardiac stress to blood cell forming stem cells.
This comprehensive review synthesizes molecular mechanisms, current therapeutics, and emerging strategies in esophageal cancer. The findings highlight breakthroughs in immunotherapy and promising future directions in targeted therapies.
Researchers developed a nano-activator that drives localized immune activation to eliminate tumors without complex antigen screening. The platform successfully remodeled the immunosuppressive tumor microenvironment and induced a durable, systemic immune memory.
A new study published in Hernia examined 39 robotic hernia repairs, with most patients returning home after one day and no hernias recurring during follow-up. Robotic technology enables greater precision and flexibility, making complex operations less invasive and more effective.
Researchers developed a GRM4-targeted lipoplex to generate NKG2D CAR T/NK cells within triple-negative breast cancer, eliminating the need for cells to reach their target. The approach improved safety and antitumor efficacy, increasing CD8+ T cell infiltration, NK cell activation, and tumor growth inhibition.
China's maternal disorder burden has declined significantly from 1990 to 2023, with substantial reductions in mortality and disability-adjusted life years. Despite progress, hypertensive disorders and indirect maternal deaths remain significant challenges, particularly among older pregnant women and those with chronic conditions.
Researchers developed a 'deuterium engineering' strategy to enhance imaging, therapy and stability of phototheranostic agents for cancer. The strategy, using deuterium substitution, improves fluorescence, reactive oxygen species generation and plasma stability.