Articles tagged with Risk Assessment
Experts propose a series of scientific principles and experimental approaches to assess potential carcinogenicity of gene therapies. Data transparency is crucial, with publicly accessible data from viral integrations site studies and clinical settings.
Researchers used genetic method Mendelian randomization to show high levels of fasting insulin cause reduction in Lp(a), rather than the other way around. Low Lp(a) is unlikely to be a risk factor for type 2 diabetes, independent of pre-existing hyperinsulinaemia and insulin resistance.
A new prediction by Nicolas Loiseau and colleagues reveals that 12.7% of marine teleost fish species are at risk of extinction, up from the IUCN's prior estimate of 2.5%. The study analyzed nearly 5,000 species without an IUCN conservation status due to insufficient data.
A WVU statistician is developing new methods to analyze curve-type data for predicting extreme weather patterns, financial turmoil and pollution levels. The research aims to create innovative tools for understanding high-resolution data and addressing regional risks in mountainous states like West Virginia.
A recent study analyzing electronic medical records found obese individuals have a 34% increased odds of SARS-CoV-2 positivity. The research highlights obesity as a significant transmission risk factor for the virus among exposed individuals, regardless of age or sex.
A nationwide study by Nanyang Technological University found that individuals who recovered from dengue are at a 55% higher risk of long-term health complications, including heart problems and cognitive disorders. This is compared to those who recovered from COVID-19.
A new study estimates that 1 in 7 Medicare beneficiaries with elevated body mass index (BMI) may qualify for semaglutide, a popular weight loss medication. The study found that maximum annual costs to Medicare could exceed $10 billion if different definitions of cardiovascular risk are considered.
A new study published in the Stroke journal found that people with brain aneurysms are at higher risk of developing mental health conditions, including anxiety. The study, which analyzed data from over 85,000 people, found that younger adults were particularly vulnerable to this increased risk.
A study found that counties with higher levels of structural racism had a 7.8-times higher estimated risk of developing cancer from traffic-related air pollutants, emphasizing the need for policies to address racial inequalities in exposure to carcinogenic traffic pollution.
A recent study published in the Scandinavian Journal of Medicine & Science in Sports found that reduced body flexibility is associated with poor survival in middle-aged men and women. After analyzing data from 3,139 participants, researchers discovered an inverse relationship between Flexindex scores and mortality risk.
A school-based citizen science program collects well water samples for analysis, revealing alarming levels of arsenic in private water sources. The initiative boosts awareness and drives action to protect public health, leading to increased testing rates and policy changes.
A new risk prediction scale specifically for American Indian adults found elevated heart failure rates compared to other population groups. The analysis identified Type 2 diabetes status, kidney damage, and high blood pressure as major modifiable determinants of developing heart failure over 5-10 years.
A new study by Korea University College of Medicine shows that direct-acting antivirals significantly reduce liver-related clinical outcomes and lower the risk of disease progression to cancer or cirrhosis, increasing life expectancy for patients with Hepatitis C. The treatment approach has a high effectiveness rate of 90%.
Researchers at the University of Gothenburg found that hearts stored in a 'heart-in-a-box' method experienced lower rates of heart failure and severe organ failure after transplantation. This breakthrough method uses hypothermic oxygenated machine perfusion to keep the heart oxygenated and functioning better.
Stroke survivors experience a range of psychosocial symptoms, including depression, anxiety, stress, fatigue, and decreased quality of life. Nurses can help identify and manage these conditions through education, therapy, and evidence-based interventions.
A new study by Northwestern University found that PrEP users frequently perceive others using the medication as promiscuous, despite knowing those who use it. The authors suggest sex-positive messaging to address this stigma and encourage a broader understanding of PrEP's benefits among vulnerable populations.
A mathematical framework reveals how the unobservable nature of effort and risk shapes research strategies and incentive structures. Scientists opt for safer projects that generate evidence of effort but hinder scientific progress.
Researchers analyzed national Medicaid data to identify perinatal and postpartum outcomes among people with intellectual and developmental disabilities. Autistic pregnant people had significantly higher probability of postpartum anxiety and postpartum depression compared to other groups.
A new study found that job strain and effort-reward imbalance at work increase the risk of developing atrial fibrillation, an abnormal heart rhythm. The research suggests that recognizing and addressing psychosocial stressors at work can foster healthy environments.
A new Cleveland Clinic study reveals that diet-derived molecules called metabolites are the main drivers of young-onset colorectal cancer risk, particularly those associated with red and processed meat. The research suggests that addressing diet with doctors can help prevent colon cancer in younger adults.
A recent study published in Radiology found that solid lung nodules were present in approximately 42% of non-smoking adults, with prevalence increasing with age. The study suggests that current nodule follow-up guidelines may lead to unnecessary follow-up examinations for low-risk individuals.
A nationwide children's hospital implemented an automated Caring Contacts texting system to provide ongoing care and support to youth at risk for suicide. The intervention helped patients feel hopeful and supported, with 83% reporting feeling moderately to very hopeful and 88% feeling moderately to very supported.
The State of Wildfires report found that carbon emissions from wildfires globally were 16% above average, with Canada and Amazonia experiencing unusually high numbers of fires. Climate change increased the likelihood of extreme wildfires in these regions by at least three times and up to six times.
The researchers argue that accurate assessment of driving skills in older adults is crucial to mitigate harm and improve safety on the road. Comprehensive driving evaluations are estimated to cost $500-$800, a significant expense that may deter those who need it most.
Researchers found that a simplified two-question test can predict smoking abstinence in cancer patients with equal accuracy as the full Fagerström Test. However, the test may not work well for Non-Hispanic Black people with a cancer diagnosis. The study aims to help doctors tailor tests for different groups.
A new heart MRI technique accurately estimates pressures inside the heart to predict heart failure risk in a general population. Key risk factors identified include age over 70, high blood pressure, obesity, alcohol consumption, and male gender.
A new study found significant improvements in aerobic fitness after 12 weeks of high-intensity interval training sessions compared to traditional, moderate exercise. Researchers suggest this time-efficient approach can be safely and effectively implemented in clinical practice for stroke survivors.
A recent study published by Florida Atlantic University found that occasional alcohol use increases the odds of intracranial hemorrhage by double when compared to those who do not drink. Daily alcohol consumption is associated with a 150% increased risk of brain bleeds from falls.
A new MIT study analyzes airline safety trends over the past few decades and finds that commercial flight has become roughly twice as safe each decade since the 1960s. The study estimates that passengers are about 39 times safer than they were in the 1968-1977 period, with a 1 in 13.7 million risk of fatality per boarding.
A new study by the Cleveland Clinic found that consuming foods with erythritol increases the risk of cardiovascular events such as heart attack and stroke. The artificial sweetener makes platelets more active, which can raise blood clot risks. This research adds to evidence that erythritol may not be as safe as previously thought.
The American College of Cardiology has released a new guidance on managing patients hospitalized for heart failure, recommending tailored therapy based on clinical trajectory. The updated Expert Consensus Decision Pathway aims to improve disease management and reduce mortality.
Research reveals that drought increases nitrate concentrations in drinking water served by majority Latino/a community water systems, exacerbating existing disparities. Arsenic levels also show variability under drought conditions.
A new study found that adding a ninth psychological health metric to Life's Essential 8 strongly predicts all-cause and cardiovascular mortality. The enhanced score showed up to 70% lower mortality risk compared to the original eight metrics.
The impacts of natural disasters on plant health can be devastating, with the potential for direct effects from disasters like pathogen or vector dispersal. Human-driven disasters also create conditions favorable to the spread of plant pathogens, leading to crop loss and disease spread.
Discrepancies in e-cigarette products containing nicotine analogues may lead to uncertainty about user exposure, hindering risk assessment for clinical and regulatory purposes. The largely unknown acute and chronic inhalation hazards and addictive potential of nicotine analogues pose a significant concern.
A University of Michigan-led study found that higher levels of metals in blood and urine are associated with a greater risk for ALS and shorter survival. Occupational exposure to metals was also linked to increased metal levels, emphasizing the need for accounting for environmental factors when evaluating overall exposure risk.
A team of UK doctors report treating the first 8 cases of artificial stone silicosis, a severe form of lung disease caused by silica exposure. The authors call for a ban on artificial stone kitchen worktops and improved workplace safety regulations to prevent further cases.
Researchers analyzed data from 63,700 patients in five clinical trials to understand the impact of clonal hematopoiesis of indeterminate potential (CHIP) on heart disease. They found that patients with CHIP had a 30% higher risk of initial heart attacks but not recurrent events.
A study found that CT scans can identify individuals at high risk of type 2 diabetes through automated analysis of various body components. The index of visceral fat showed the highest predictive performance for diabetes.
Research finds that a quartet of factors contributes to the 18-year US lifespan gap, with individual risks rising in tandem with more factors. A simple scoring system helps identify those at risk of early death.
A qualitative study highlights the dangers of unregulated online semaglutide sales, with vendors shipping falsified products. The US has seen a 1500% increase in semaglutide-related calls to poison centers, underscoring the need for enhanced pharmacovigilance.
Researchers have identified nearly 300 common and over 20 rare genetic variants as significant risk factors for schizophrenia. The study emphasizes the role of multiple genes rather than single-gene causation, revealing complexity in the mechanisms underlying the disorder.
Researchers developed a formula and assessment tool to calculate fall risks for older adults, considering factors like poor oral and cognitive function. The tool is simple to use and may assist in prevention and follow-up care.
A study published in JAMA Oncology found that regular aspirin use significantly lowers the risk of colorectal cancer in individuals with higher lifestyle-related risk factors. The benefits were most pronounced among those with unhealthiest lifestyles, where treating 78 patients with aspirin would prevent one case of colorectal cancer o...
A new AI-powered predictive model can generate comprehensive soil liquefaction risk maps, enabling urban planners and engineers to visualize high-risk areas and make informed decisions. The model achieved high accuracy in predicting soil classifications and N-values, validating its effectiveness in enhancing urban resilience.
A new analysis found that people hospitalized for heart disease, stroke, or cardiovascular diseases are 83% more likely to be diagnosed with anxiety, depression, or other psychiatric conditions within the first year after hospitalization. Early mental health screening and intervention are crucial for patients and their loved ones.
A recent study published in Frontiers in Immunology highlights the crucial role of tissue-resident memory T cells in non-small cell lung cancer. The research found that these cells can significantly impact patient outcomes and guide personalized treatment strategies, particularly those involving immunotherapy.
A new study found that full-time wheelchair and motorized scooter users encounter obstacles that cause them to fall, resulting in scrapes, bruises, or more serious injuries. The researchers also discovered a 'disuse disability cycle' where limited activities lead to physical decline, increasing the risk of future falls.
Researchers at MedUni Vienna have identified AF1Q as a promising biomarker to predict gastric cancer recurrence risk. The study found that 97.8% of tumour samples had elevated AF1Q levels, associated with higher recurrence risk and lower survival chances.
Research highlights the need for further study on the impact of sustained heat exposure on hormone release and action. Heat exposure is associated with decreased fertility, increased risks of pregnancy complications and menopause symptoms, as well as worsened conditions like thyroid disorders and diabetes mellitus.
A study published in PLOS Medicine found that abnormal routine blood test results can predict cancer risk in patients with abdominal symptoms. The researchers analyzed data from over 470,000 patients and identified specific blood abnormalities linked to increased cancer risk across different age groups and sex.
Researchers found that abnormal results from routine blood tests were linked to a higher risk of being diagnosed with cancer within a year. The study estimated that taking these results into account could lead to an extra six people with undiagnosed cancer being urgently referred for treatment.
A new study found that adults with diabetes who meet the recommended physical activity guidelines may offset the increased mortality risk associated with excessive sitting time. The study analyzed data from over 12,000 adults with diabetes and found that those who were physically active had a lower risk of death compared to those who s...
The new risk calculator estimates nearly 16 million people will be newly ineligible for cholesterol and blood pressure therapy, resulting in 107,000 additional heart attacks and strokes over 10 years. The change would disproportionately affect men between 50 and 69 years old.
A recent study published in ESC Heart Failure found that kidney dysfunction can be used as a criterion to stratify patients requiring implantable defibrillators. The research identified two key independent predictors for the risk of sudden cardiac death: left ventricular ejection fraction and estimated glomerular filtration rate.
A special section of WORK: A Journal of Prevention, Assessment & Rehabilitation highlights the varying physical elements and requirements for different occupations. PES frameworks are being developed for a range of physically active occupations to support personnel undertaking physically demanding tasks.
A new study found that the incidence of hepatitis C virus (HCV) reinfection among men with HIV is 10-fold higher than primary infection rates in New York City. The researchers identified receiving semen in the rectum as the only risk factor for reinfection, contradicting previous assumptions about transmission routes.
Researchers found that most Powassan-positive bites cause nonspecific presentations without symptoms, and estimated 3,000-5,000 people in the US are exposed to ticks carrying the virus each year. The study used a new testing approach to detect the virus in ticks and linked it to human disease outcomes.
A study estimates that prescribing NSAIDs to high-risk groups in England may result in significant healthcare costs and lost productivity. The estimated total loss of quality-adjusted life years (QALYs) over 10 years is 6,335 at a cost of £31.43 million.
A study published in JAMA Network Open found that years of high systolic blood pressure increase the risk of stroke, with Black and Hispanic patients facing a higher risk. Early diagnosis and controlled high blood pressure are crucial to preventing stroke, especially in these populations.