Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A cross-sectional study found that TV football game food ads are often high in sodium, calories, and fat content. This can pose a risk to adults with pre-existing heart conditions, who may be vulnerable to dietary deviations due to frequent exposure to advertising.
Recent research reveals innovative targets for glucose and fat metabolism, including GLP-1 receptor agonists, SGLT2 inhibitors, and GPCR agonists. These emerging therapies aim to improve insulin sensitivity, glucose uptake, and glycemic control.
Researchers discovered that pancreatic β cells produce a neuroprotective agent called Fibroblast Growth Factor 23 (FGF23), which can stop amyloid-β-induced neuronal cell death. FGF23 may increase ribosomal proteins, helping to maintain homeostasis in neurons.
The European Society for Paediatric Endocrinology and the European Society of Endocrinology will host the first-ever joint Congress on May 10-13, 2025. The event aims to bring together paediatric and adult endocrine specialists from across Europe and the world to collaborate and celebrate endocrinology.
A new study from the Salk Institute has discovered that a protein called BCL6 plays a crucial role in maintaining healthy muscle mass. Increasing BCL6 levels successfully reversed muscle losses in mice, suggesting that pairing GLP-1 medications with a BCL6-boosting drug could help counteract unwanted muscle loss.
A retrospective cohort study of 44,000 individuals found associations between baseline fasting glucose levels, age, sex, and body mass index with the development of diabetes. The study highlights individual variation in diabetes risk according to commonly measured clinical variables, suggesting potential for targeted interventions.
A recent study by researchers from the University of Toronto found that older adults who experienced parental divorce during childhood have a 60% higher odds of stroke. The study controlled for known risk factors and still showed a strong association between parental divorce and stroke.
Researchers analyzed data from 13,205 adults aged 65 and over, finding that those who had experienced parental divorce before age 18 had 1.61 times higher odds of having a stroke. This association remained even after controlling for known risk factors such as diabetes and depression.
A new study found disparities in access to semaglutide based on insurance plan, job industry, sex, and other factors. Individuals with female identities, preferred provider organization coverage, and antidepressant use were more likely to start taking semaglutide compared to males or those with certain employment industries.
A cohort study found that insurance plan type and structure play a crucial role in determining access to semaglutide for adults with obesity. The findings suggest that targeted interventions at the insurance level could improve equity in obesity treatment access.
This study found a U-shaped association between waist circumference and all-cause mortality in women, and a J-shaped trend in men. The optimal waist sizes for minimizing mortality risk were 107 cm for women and 89 cm for men.
A recent study published in Nature Medicine analyzed over 2 million veterans taking GLP-1RA medications, finding benefits to cognitive and behavioral health while revealing increased risks for pancreatitis and kidney conditions. The study also showed decreased risks of seizures, addiction, suicidal ideation, and neurocognitive disorders.
A study published in Nature Metabolism found that four percent of Greenland's Inuit population has a gene variant that increases their risk of type 2 diabetes by tenfold. Exercise has been shown to increase insulin sensitivity in these individuals, suggesting it may be an effective way to reduce their risk of developing the disease.
Researchers discover immune cells regulate blood sugar levels by stimulating glucagon production in the pancreas. This complex neuroimmune-hormonal circuit reveals a new way the body maintains stable glucose levels, especially during periods of low energy.
A cohort study found that individuals with higher radon exposure are at a greater risk of developing gestational diabetes during pregnancy. The study suggests a potential link between radon exposure and metabolic health in nulliparous pregnant women.
Researchers at Binghamton University have developed a new paper-based biosensor system that uses bacterial spores to monitor glucose levels in sweat, eliminating the need for finger-stick devices. The system is shelf-stable, self-replicating, and can endure harsh environments, making it a promising alternative for diabetes management.
Additional research is required to explore the relationship between COPD and metabolic syndrome, focusing on outcomes, intervention trials, and health services research. This will help shift from a COPD-focused approach to an integrated care approach considering all comorbidities.
Researchers found that brown adipose tissue enhances exercise endurance and supports healthy aging by improving blood circulation and reducing cellular stress. The study suggests that treatments mimicking BAT's benefits could lead to innovative therapies for improved energy levels and heart health.
Researchers will expand on data gathered since 2008, uncovering insights into biologic, genetic, behavioral, environmental and social factors influencing Hispanic/Latino health. The study aims to inform targeted precision prevention and medical care in cardiovascular diseases and other conditions.
The DASH Diet has been ranked as the best heart-healthy diet and second-best overall in US News & World Report's 2025 rankings. Developed by Pennington Biomedical Research Center scientists, the diet emphasizes fruits, vegetables, and whole grains, while reducing saturated fat and added sugars.
A large study found that patients with diabetes taking GLP-1 receptor agonist drugs had lower rates of hospital readmission, wound re-opening, and hematoma after surgery. Improved blood sugar control was not the likely mediator, suggesting other mechanisms may be at play.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Researchers at Karolinska Institutet used AI to analyze brain images from 70-year-olds and found that factors like inflammation and high glucose levels are associated with an older-looking brain. A healthy lifestyle, on the other hand, was linked to brains with a younger appearance.
A recent study discovered that assessing an individual's perceived walking speed relative to peers can identify those at risk of metabolic diseases. Faster walkers had lower risks of diabetes, hypertension, and dyslipidemia.
Women with gestational diabetes who engaged in moderate-to-vigorous intensity physical activity during pregnancy had a lower risk of preterm birth compared to those who were less active. Concentrated periods of physical activity also offered similar benefits in reducing preterm birth risk.
The National Institute of Neurological Disorders and Stroke has awarded researchers at the University of Tennessee Health Science Center $2.18 million to investigate a new small molecule that activates SERCA2, aiming to correct calcium imbalances caused by diabetes after a stroke.
The network's all-new digital report boasts over $56.1 million in total cost-of-care savings, with $44.6 million in rewards shared among providers. Ochsner Health Network also expands access to care and improves health outcomes through its collaborative partnerships and technological advancements.
A UK study published in Diabetic Medicine found that over half of pregnant women with gestational diabetes were undiagnosed due to slow NHS blood test processing. Faster blood processing identified additional cases, leading to improved health outcomes for mothers and babies.
The five-year national research study will examine the effectiveness of medically tailored meals in reducing gestational diabetes and Type 2 diabetes prevalence among pregnant and postpartum women from historically marginalized communities. Nearly 1,000 participants will be assessed for maternal health outcomes.
A new study published in Lancet Gastroenterology and Hepatology found that a combined screening approach can detect liver damage in people with type 2 diabetes. The method involves elastography, an ultrasound-based technique, which was found to be willing to be adopted by most patients. Early detection of liver fibrosis is crucial, as ...
Researchers will build a wireless bioelectronic device, named BIOSYNC, to regulate appetite through physiological satiety pathways. The device aims to produce two peptide therapeutics simultaneously with reduced side effects and better adherence to therapy.
Researchers have identified new potential therapeutic targets for diabetic kidney disease (DKD), a leading cause of kidney failure. The study reveals common and cell-type-specific changes caused by insulin-resistance, representing new targets for pharmacological or targeted gene therapy approaches.
A six-month clinical trial found that empathetic phone calls led to significant improvements in blood sugar control for low-income adults with diabetes. The patient-driven approach empowered individuals to receive support at a pace that suited their needs and schedules.
The addition of jabuticaba peel flour increased the bread's fiber content by over 50% and raised its antioxidant capacity by 1.35-3.53 times, leading to improved blood sugar control and insulin response. The study found that satiety increased after consuming the bread with jabuticaba peel flour, suggesting a lower glycemic index.
Researchers at Karolinska Institutet have identified two types of metabolic-associated fatty liver disease, a liver-specific type and a systemic type that affects other organs. The discovery could lead to improved diagnosis and treatment of this growing patient group, with potential benefits for cardiovascular health.
The novel compound HPH-15 outperforms metformin by activating AMPK at lower doses, improving glucose uptake and reducing fat accumulation in high-fat diet-induced obese mice. Additionally, it exhibits antifibrotic properties, potentially addressing liver fibrosis.
A new study of over 4,000 postmenopausal women found that weaker handgrip strength is associated with a greater likelihood of having diabetes. Women who had been postmenopausal for more than 10 years showed an inverse relationship between handgrip strength and diabetes prevalence.
A research team developed a diabetes prediction system utilizing clinical and genetic data through deep learning AI algorithms. The system predicts the risk of developing type 2 diabetes within five years, enabling early preventive strategies.
Researchers found that certain cancer treatments, such as immune checkpoint inhibitors, can trigger damaging levels of inflammation in the heart and increase risk of heart disease. This is because these treatments interfere with immune regulation in the heart's largest blood vessels.
A new review reveals how sleep disturbances exacerbate dementia symptoms, impacting overall health and caregiver well-being. The study emphasizes the need for holistic approaches to address coexisting conditions like cardiovascular disease and diabetes.
Researchers have developed a 3D artificial skin model with all three layers, simulating diseases and injuries more accurately. The model can replace animals in toxicological studies of medicines and cosmetics, enabling the development of new treatments without animal testing.
A U-shaped association between waist circumference and all-cause mortality was found in women, while a J-shaped trend was observed in men with type 2 diabetes. The study suggests that optimal waist circumference thresholds for minimizing mortality risk are 107 cm for women and 89 cm for men.
Dr Bøsch's work explores betalains' potential to impact blood pressure, diabetes, cardiovascular health, and gut microbiota. The award highlights the significance of her research in advancing functional food and feed applications with implications for human and animal health.
Proteins moving slowly through cells lead to widespread dysfunction, affecting gene expression, ribosome production, and more. Researchers propose restoring protein mobility as a therapeutic target for treating chronic diseases.
A systematic review of 18 randomized controlled trials found that drinking enough water can help with weight loss and prevent kidney stones. Drinking eight cups a day significantly decreased the likelihood of getting another kidney stone, while six cups a day helped adults lose weight.
A study estimates that approximately one-third of eligible US adults without diabetes were excluded from clinical trials supporting GLP-1 and GLP-1/GIP medications. The FDA should consider updating labeling to advise caution on generalizing these medications' safety and effectiveness to excluded populations.
The NYU-CUNY Prevention Research Center will improve diabetes management among low-income immigrant populations through culturally tailored education and support. The center aims to enhance capacity for community partners to adopt and implement evidence-based interventions effectively.
A new study from Northwestern Medicine reveals a significant increase in severe maternal morbidity and birth complications in Illinois between 2016 and 2023. The findings highlight the impact of chronic health conditions such as obesity, hypertension, and mental health disorders on pregnancy outcomes.
Researchers at Monash University have discovered that LXA4 can halve inflammation and scar formation in diabetic hearts, offering a promising new treatment option. The study's findings suggest that LXA4-based therapies could be used to manage diabetic heart disease more effectively.
Christian Wolfrum will serve as NTU's chief academic officer, overseeing educational and research excellence, while strengthening talent development. He brings experience in translating research into real-world applications, having co-founded biotechnology firm Glycemicon AG.
A new study reveals that infants exposed to gestational diabetes mellitus (GDM) in utero may not have as weighty of challenges as previously believed. GDM-exposed babies showed slower fat gain during their first year, suggesting a flexibility in early-life growth patterns.
Researchers from Universidad Miguel Hernandez de Elche found that bisphenol analogs BPF and BPS, marketed as safer alternatives to BPA, accumulate in biological membranes and disrupt endocrine function. The study suggests these compounds pose health risks similar to those of BPA.
Proactive screening of diabetic patients with coronary heart disease does not improve long-term survival rates or lower future cardiac events, according to a new study. The study found that focusing on proven interventions like medication management and lifestyle changes can help patients with diabetes lead healthier lives.
Researchers at the University of Nottingham have discovered that GLP-1 receptor agonists may be effective in reducing alcohol consumption. The study suggests that this type of diabetes medication could potentially treat excessive alcohol use and lead to a reduction in alcohol-related deaths.
A new study maps the gut microbiome of over 1,300 children under five years old in Ethiopia, revealing a clear link between gut bacteria composition and the duration of diarrhea. The researchers identify beneficial bacteria that produce short-chain fatty acids, which are lacking in children with chronic diarrhea.
The Ochsner Accountable Care Network achieved its eighth consecutive year of top-ranking results in clinical performance and healthcare savings. The network saved Medicare $30.9 million for over 58,000 beneficiaries in 2023, improving health outcomes while reducing costs.
Researchers from UAB have developed a gene therapy that reverses metabolic dysfunction-associated steatohepatitis (MASH) in mice, and most obese and type 2 diabetic patients could benefit from this treatment. The therapy, based on the fibroblast growth factor 21 protein, mediates long-term reversal of liver fibrosis and MASH.
A study found that monochromatic infrared light combined with physical therapy significantly reduced pain and improved sleep quality in patients with peripheral diabetic neuropathy. The treatment was effective in reducing symptoms and improving functionality for patients with intense pain.
Researchers found semaglutide and liraglutide substantially decrease AUD hospitalization risk compared to approved medications. Clinical trials are needed to confirm these findings and explore their efficacy in treating AUD.
The editorial highlights how digital tools improve patient outcomes through better monitoring, individualized care, and seamless communication between patients and healthcare providers. Digital health innovations also address key challenges such as data privacy and accessibility.