A new University of Pittsburgh analysis found that obese women are more likely to experience stillbirths due to placental diseases and hypertension. The study suggests that monitoring these complications and promoting weight loss before pregnancy can reduce the risk of stillbirth.
Scientists developed a novel treatment strategy for patients with severe intolerance to antihypertensive medication, involving fractional dosing and alternative formulations. Blood pressure was significantly reduced among patients after just six months on the new approach, without debilitating side effects.
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A new study by Montefiore and Einstein researchers recommends referring pregnant women with severe headaches and elevated blood pressure immediately for neuroimaging and monitoring. The study found that high blood pressure is a major indicator of preeclampsia, which can lead to pregnancy complications.
A UCI study found that acupuncture treatments significantly reduced systolic and diastolic blood pressures in hypertensive patients. The treatment also lowered levels of norepinephrine and renin, which constrict blood vessels and increase blood pressure.
Researchers found small clusters of cells with genetic mutations that can lead to primary aldosteronism, a form of hypertension. The study suggests most people have these origins of the condition already, and further research could improve diagnosis and treatment.
African-American participants showed a significant decline in dementia incidence rates from 1992 to 2011 compared to a stable rate among Yoruba individuals in Nigeria. The study suggests that medication for cardiovascular conditions may contribute to the decline.
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A modeling study predicts treating hypertension in China could prevent between 600,000 and 1,000,000 cardiovascular disease events annually. The intervention is projected to be borderline cost-effective, with costs ranging from $10,000 to $18,000 per quality-adjusted life year gained.
Researchers found that patients with pharmacist-included care teams had better blood pressure control results than those without, with a systolic blood pressure drop of 6.1 mmHg after nine months.
A Japanese study of over 4,000 people found that those consuming the most salt had a higher risk of developing high blood pressure. Participants who gradually increased their sodium intake also showed gradual increases in blood pressure.
A big data study found that triamterene significantly lowers blood pressure when taken with hydrochlorothiazide, a commonly prescribed diuretic. The combination of the two drugs consistently reduces blood pressure in patients with or without other antihypertensive agents.
Robson Santos will focus on the analysis of alamandine's functions in cardiovascular disease. He recently discovered the hormone as part of his collaboration with Professor Michael Bader at the MDC.
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A new study published in Circulation reveals African-Americans experience sudden cardiac arrest at a higher rate than Caucasians, with significant differences in age, diabetes prevalence, and hypertension rates. The study suggests that prevention strategies may need to be tailored to different racial and ethnic groups.
Research published in the American Heart Association's journal Circulation found that blacks are more likely to experience sudden cardiac arrest, particularly at younger ages. The study also identified a higher prevalence of non-coronary heart problems among black patients, including congestive heart failure and left ventricular hypert...
Researchers found that high blood pressure at a younger age can affect cognitive performance many years later. Participants with high blood pressure scored more poorly on tests of attention and executive function, highlighting the importance of managing factors that impact brain aging.
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A yearlong study found that patiromer can reduce elevated blood-potassium levels and prevent life-threatening adverse events in patients with chronic diabetic kidney disease. The drug consistently maintained normal serum potassium levels over 52 weeks, with minimal discontinuation due to adverse events.
Researchers created a scoring system, called the Healthy Beverage Index, to evaluate beverage intake patterns and their impact on health conditions like obesity and diabetes. The index scores are correlated with better cholesterol levels, lowered risk of hypertension, and lower blood pressure in men.
A recent study published in the American Journal of Hypertension revealed a decline in blood pressure levels among US children and adolescents over the past decade. The study analyzed data from the National Health and Nutrition Examination Survey from 1999-2012, finding that mean blood pressure levels, as well as the prevalence of elev...
A new scoring method, the Healthy Beverage Index (HBI), evaluates overall beverage intake quality and its association with cardiometabolic risk factors. Higher HBI scores are linked to more favorable lipid profiles, decreased hypertension risk, and improved C-reactive protein levels.
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A new study has found a significant association between high blood pressure and the presence of phthalates in children and adolescents. The chemicals were used as replacements for DEHP, which was previously linked to detrimental effects on human health.
A recent study found that approximately 1 in 6 aging individuals would be reclassified as having 'at goal' blood pressure under the new guidelines, despite frequent use of antihypertensive medications. The study suggests that less stringent blood pressure goals may increase the risk for heart attacks and strokes among older adults.
Research in Japan reveals worsening cardiovascular risk factors, including hypertension and high cholesterol, despite global declines in the US. Improved data collection and clinical trials are crucial to developing new treatments and improving patient outcomes worldwide.
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New studies reveal that hypertensive individuals experience higher rates of cognitive decline compared to non-hypertensive populations. Additionally, African Americans with hypertension bear a disproportionate burden of disability and mortality associated with the condition. These findings underscore the importance of effective managem...
A new study suggests a genetic link between high blood pressure and reduced Alzheimer's disease risk, with antihypertensive drugs possibly playing a protective role. Researchers analyzed genetic data from over 17,000 individuals and found a significant association between higher systolic blood pressure and lower Alzheimer's risk.
A study of 2,500 young adults found that even mild elevations in blood pressure can lead to subclinical heart damage by middle age. Persistent high blood pressure is a known risk factor for cardiovascular disease, but the new study suggests that 'high-normal' pressure may also be a concern.
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The journal celebrates its 10-year milestone with a special issue featuring articles on blood pressure targets, cardiac care for women, and pharmacogenomics. Recent advances and emerging challenges in specific areas of cardiology are reviewed.
A new study published in the American Journal of Clinical Nutrition found that a DASH-style diet with lean, unprocessed pork as the primary protein source reduced blood pressure and had similar effects when chicken or fish was used instead. The study included 19 participants with elevated high blood pressure and demonstrated the versat...
A study of over 250,000 patients suggests that low blood pressure is a greater risk factor for death after surgery than high blood pressure. The research found that patients with low systolic or diastolic pressure had significantly increased odds of perioperative mortality.
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People with metabolic syndrome face a higher risk of cardiovascular death than those without the condition. The study found that having diabetes or high blood pressure significantly elevates this risk. Women with metabolic syndrome were also at a greater risk of death from any cause compared to their male counterparts.
The European Clinical Consensus Conference concludes that research into renal denervation for high blood pressure should not be abandoned until high-quality research is completed according to agreed-upon standards. The group also emphasizes the need for standardization in treatments, populations, methods, and adherence measures.
A study published in JAMA Network found that nearly 35 percent of all U.S. adults and 50 percent of those 60 years or older had metabolic syndrome in 2011-2012. The condition is characterized by a combination of health conditions including obesity, high blood pressure, type 2 diabetes, and poor lipid profiles.
Scientists have identified the PDE3A gene responsible for a rare syndrome characterized by hereditary hypertension and short fingers and toes. The gene mutations lead to overexpression of phosphodiesterase, causing blood vessels to narrow and stiffen, resulting in high blood pressure.
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Researchers identified smooth muscle cells as a major contributing factor to vascular stiffness, a significant contributor to hypertension. The study's findings suggest that targeting these cells may lead to new possibilities for drug treatments for the disease.
A rare genetic syndrome is associated with increased blood vessel resistance, which may contribute to hypertension. The study identifies mutations in the PDE3A enzyme that alter its activity and increase blood pressure. The findings suggest new avenues for investigating hypertension causes and developing targeted therapies.
A recent study has identified the enzyme responsible for obesity-related hypertension, which breaks down a molecule necessary for relaxing blood vessels. The research suggests that targeting this enzyme may lead to new treatment options for obese patients with high blood pressure.
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A study of over 6,600 veterans found that using both VA care and a Medicare Advantage plan did not have any negative impact on quality of care, but raised concerns about duplicate federal spending. The researchers also noted that many veterans relied more heavily on VA care than Medicare Advantage visits.
A new x-ray study reveals how a hypertension drug binds to a cellular receptor, providing valuable insights for designing more effective medications. The research could lead to the development of targeted drugs with fewer side effects.
Researchers studying sleep apnea aim to understand the link between breathing patterns and blood pressure control in the brain. The IUPUI study may lead to innovative treatments for hypertension.
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A Spanish study involving over 4,400 adults found no link between regular yogurt consumption and improved physical and mental parameters. The study suggests that more specific instruments are needed to determine potential benefits of yogurt on health.
Michigan State University researchers are investigating whether belly fat hormones cause high blood pressure by communicating with blood vessels in the abdomen. Visceral fat, a harmful type of fat that surrounds organs and blood vessels, is believed to play a key role in this process.
Researchers at University of Maryland School of Medicine discovered a key mechanism for thiazide drugs' failure in some patients, leading to the development of new treatments. The study found nearly 400 genes change their activity to help regulate salt retention, shedding light on how the body counteracts thiazides.
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Research finds that children experiencing multiple traumatic events are more likely to develop hypertension and coronary artery disease later in life. Studies show a significant increase in systolic pressure among those with ACEs, even after adjusting for other risk factors.
A systems-wide genetic study of blood pressure regulation in the Framingham Heart Study identified four groups of genes linked to blood pressure that warranted further study. The researchers validated one key driver gene, Sh2b3, which plays a causal role in dysregulation of blood pressure in humans.
A recent study by Duke-NUS Medical School researchers found an association between meals eaten away from home and high blood pressure in university-going young adults. The study, which surveyed over 500 participants, showed that pre-hypertension was prevalent in 27.4% of the population, with men more likely to be affected than women.
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Researchers found that women were excluded from rtPA treatment for reasons unrelated to their sex, including advanced age and large strokes. High blood pressure was a common reason for exclusion in women, highlighting the importance of treating this condition to improve stroke treatment outcomes.
A review emphasizes the importance of accurate blood pressure measurement for early diagnosis and management of hypertensive disorders in pregnancy. It identifies factors leading to inaccuracies and calls for more well-designed studies on optimal vital sign predictors to guide assessment in obstetric shock.
A new study found that pears, rich in phenolics and antioxidants, can support beneficial probiotic bacterial response while controlling stomach-related diseases. The results suggest a pear-enriched diet may provide efficient management options for diet-linked non-communicable diseases.
A study published in JAMA Network found that combining folic acid with the hypertension medication enalapril significantly reduced the risk of first stroke among over 20,000 Chinese adults with high blood pressure. The treatment also showed significant reductions in ischemic stroke and composite cardiovascular events.
A Kaiser Permanente study found that expanding blood pressure screenings to non-primary care settings can help identify more patients with high blood pressure and improve management. The study reported that patients identified with hypertension in non-primary care settings were more likely to be older, male, and non-Hispanic white.
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Researchers analyzed data from over 450 men trying to conceive, finding that heavy work-related activity, high blood pressure, and multiple medications may lower sperm counts. The study suggests environmental factors and health status play a significant role in semen quality.
A recent study published in the American Journal of Hypertension found a strong association between adolescent BMI and both systolic and diastolic blood pressures. The study, which examined over 715,000 Israeli adolescents, revealed a significant increase in obesity rates and high blood pressure among teens.
Researchers found that salt accumulates in skin and tissue to control infection, increasing macrophage activation. High-salt diet also cleared up bacterial footpad infections in mice.
A 10-year-old boy developed seizures and hypertension after consuming excessive licorice sweets. The case study highlights the dangers of overconsumption of glycyrrhizic acid in licorice, a risk particularly high for children with low body weight. Manufacturers are urged to state recommended daily limits as a safety measure.
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A study of European children found that spending over two hours daily watching TV increases the risk of high blood pressure by 30%. Not engaging in physical activity or doing less than an hour of exercise daily also raises this risk by 50%
A new study found that lowering systolic blood pressure to below 140 mm Hg significantly reduces the risk of stroke in people over 60, with especially high risks for Hispanics and blacks. The study also highlights the importance of targeting this group with specific treatment guidelines.
A study found Deaf adults have high risk factors for heart disease, diabetes, and hypertension, with many undiagnosed or untreated conditions. Poor communication and lack of interpreters exacerbate the issue, leading to missed diagnoses and ineffective treatment.
Researchers identified systolic blood pressures above 150 as a critical threshold for increased risk of death or cardiovascular events. Delays in intensifying treatment by over 1.4 months also tied to higher risk, while reassessments beyond 2.7 months increased mortality.
Duke researchers discovered a gene called Raf that acts as a switch to turn on Yorkie, making fly hearts grow bigger. The study sheds light on the genetic circuitry of signals governing growth and may help understand how human hearts respond to disease.
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A study of 825 women with mild gestational diabetes found that those with preeclampsia/gestational hypertension had a higher frequency of subsequent hypertension and metabolic syndrome. Women who delivered preterm and had preeclampsia/gestational hypertension were at greatest risk.
A new study found that middle-aged heavy drinkers (more than two drinks daily) had a 34% higher risk of stroke compared to light drinkers. Heavy drinking also increased stroke risk in mid-life, regardless of genetic and early-life factors.
AP39 replenishes hydrogen sulfide levels, lowering heart rate and blood pressure, with potential for new cardiovascular therapies.