A multicenter study found that metformin lowers the chance of late miscarriage and premature birth among women with polycystic ovary syndrome (PCOS), but has no effect on gestational diabetes risk. The medication also led to less weight gain during pregnancy, a positive finding for overweight women.
Low levels of vitamin D during pregnancy and breastfeeding have been linked to differences in social behavior in children later in life. The study found that rats born to mothers with vitamin D deficiency displayed abnormal social behaviors, altered brain chemistry, and impaired learning and memory.
A new study found that children born to mothers with a larger waist size (80 cm or more) before pregnancy are at a 65% higher risk of developing autism. The research suggests inflammation may play a key role in this link.
A study by University of North Carolina at Chapel Hill found that primary care physicians feel underequipped to address prenatal oral health, with only 45% feeling prepared. The authors suggest improving training and education on oral health for primary care physicians.
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Research suggests that race and pre-pregnancy body mass index (BMI) affect leptin and adiponectin levels, which can predict weight gain during pregnancy. Lower levels of adiponectin are associated with higher risk of gestational diabetes, while higher leptin levels are linked to pre-eclampsia.
A new study in mice found that prenatal exposure to di-(2-ethylhexyl) phthalate (DEHP), a common endocrine disruptor, can lead to decreased fertility and reproductive abnormalities in males. The researchers discovered that even the offspring of male mice exposed to DEHP during pregnancy exhibited similar reproductive problems.
Research in mice found that exposure to low levels of BPA during pregnancy can lead to altered brain development and behavior later in life. The study, presented at ENDO 2018, shows that even low doses of BPA can affect the timing of neuron birth and lead to permanent changes in brain function.
A 3D tissue model of the developing heart has been created using human induced pluripotent stem cells, allowing for more accurate and reliable drug safety testing for pregnant women. This model mimics early stage human heart development, providing a valuable tool for assessing embryo toxicity and fetal development.
Researchers have developed a more accurate way to screen for preeclampsia, a condition affecting 2-3% of pregnancies, which can lead to serious health effects for both mother and child. The new screening method uses biomarkers to identify high-risk women, resulting in increased detection rates for preterm-PE by up to 82%.
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A new study reveals that 68% of genetic mutations causing fetal death affect the placenta, highlighting its critical role in development. Placental defects often occur alongside brain, heart, and circulation issues.
Researchers found that L-arginine supplementation increased blood vessel development in the placenta and reduced low birth weight/preterm birth and stillbirth. The study suggests that L-arginine may be a critical component in regulating blood vessel development, with implications for other conditions linked to poor birth outcomes.
A new study found that low levels of L-arginine in pregnant women with malaria are associated with worse pregnancy outcomes. Supplementing these women with L-arginine may improve birth weights and viability among their babies, according to research published in Science Translational Medicine.
Researchers developed a mathematical model to calculate bisphenol A levels reaching the fetus, with 100 pregnant women as test subjects. The P-PBPK model monitors compound effects on pregnancy and future health outcomes.
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A new study from Stanford Medicine found that female soldiers who give birth within six months of returning from military deployment face a higher risk of having a preterm baby. The study also found that women giving birth soon after deployment are younger, with lower education and pay.
A review of available evidence found that pregnant women can safely engage in up to 35 minutes of high-intensity aerobic exercise at air temperatures of up to 25°C and 45% relative humidity. They can also participate in hot baths or saunas for up to 20 minutes without reaching the recommended core temperature limit of 39°C.
A study following women with preeclampsia found a significant increase in cardiovascular risk factors, including high blood pressure, diabetes, and high cholesterol. Women who had follow-up medical care after preeclampsia were less likely to receive proper monitoring for these conditions.
Women who breastfed for six months or more during pregnancy had higher levels of HDL cholesterol, lower triglycerides, and healthier carotid artery thickness compared to those who never breastfed. This suggests breastfeeding may reduce the risk of heart disease in women with normal blood pressure during pregnancy.
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Research from Imperial College London found that taking daily fish oil capsules during pregnancy reduced the risk of egg allergy in children by 30%, while daily probiotic supplements reduced the risk of eczema by 22%. No significant impact on allergy or eczema risk was found from avoiding potentially allergenic foods.
Children born to mothers taking metformin during pregnancy are at increased risk of having obesity or overweight, according to a new study. The research found that the medication crossed the placenta and affected fetal development, leading to higher BMI scores in children.
A study published in JNeurosci found that a woman's immune system during pregnancy influences the development of her child's brain network, which may be linked to psychiatric disorders such as autism and schizophrenia. Higher maternal immune activation was also associated with improved cognitive ability in infants.
A new study published in Ultrasound in Obstetrics & Gynecology found that pregnant women with hypertension can safely monitor their blood pressure at home using a validated machine. The study of 108 women showed no differences in adverse maternal, fetal, or neonatal outcomes compared to those monitored in a clinic.
A new study identifies novel molecular biomarkers of preeclampsia, which may be used to develop an early diagnostic blood test. The findings suggest that small non-coding RNAs in a pregnant woman's blood can predict the risk of developing preeclampsia.
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Researchers argue that taking action before pregnancy is essential to prevent obesity, mental health problems and substance abuse in young people. The first 1000 days of life are crucial, but current policies start too late. Investing in adolescent development can guarantee a healthy future for both parents and children.
Researchers emphasize that addressing obesity, mental health issues, poor nutrition, and substance abuse in adolescents before pregnancy is essential for a healthy start to life. The study highlights the importance of engaging health services with young adults and creating healthier environments to prevent intergenerational health risks.
Researchers at the University of Edinburgh identified a hormone called DHEA that can prime cells for implantation and increase active hormones. This discovery could lead to new treatments for infertility in women over 40.
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A Drexel University study explores how social media platforms like Facebook facilitate healing for women who experience pregnancy loss and stigmatized disclosures. Researchers found that sharing personal stories online reduces stigma, builds support networks, and promotes emotional well-being.
Women with asthma who use short-acting asthma relievers take longer to become pregnant than those without asthma. In contrast, long-acting asthma preventers do not appear to reduce fertility, suggesting that improved asthma control could lead to faster conception rates.
Research highlights shortcomings in pregnancy preparation and prenatal care for women with diabetes, calling for improved care coordination and technology use. A nationwide commitment is needed to deliver integrated reproductive and diabetes healthcare interventions to enhance pregnancy outcomes.
Women with asthma who use short-acting asthma relievers take longer to become pregnant than those without asthma, but using long-acting asthma preventers has no impact on fertility. The study of over 5,000 women in Australia, New Zealand, and Ireland shows a significant difference between short-acting and long-acting treatments.
A recent study published in Epidemiology found that high intake of sugary drinks is associated with lower fertility rates. The researchers analyzed data from 3,828 women and their male partners, finding that consuming at least one soda per day reduced female fecundability by 25% and male fecundability by 33%.
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Researchers have identified risk factors for sleep apnea during pregnancy, including frequent snoring and older maternal age. A calculator tool has been developed to help obstetric providers identify women at risk for the condition, enabling early referral for definitive testing.
A study of nearly 3 million births found the ACA's dependent coverage provision led to increased use of prenatal care, higher private insurance payments for births, and a modest decline in preterm births. However, it did not affect cesarean delivery rates or low birth weight.
A University of Cincinnati study reveals that TV's influence on pregnancy and childbirth is stronger than many women think, with educated women downplaying its impact. However, those with lower education levels often rely on reality TV as a valuable source of information.
Researchers found that 6-year-old children born to mothers with very low vitamin D levels during pregnancy had bigger waists and more body fat. Vitamin D supplements during pregnancy might help stem childhood obesity. The study, published in Pediatric Obesity, examined data from 532 mother-child pairs in Greece.
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A new tool using biomedical photonics is being explored to improve uterine transplant surgery by providing real-time data on tissue perfusion and viability. The study found that multispectral imaging proved effective in mapping oxygen saturation over the entire graft, demonstrating advantages over existing methods.
Researchers discovered that glands in the uterus must connect directly with the embryo for it to implant and begin a healthy pregnancy. The Vangl2 gene plays a crucial role in this process, producing molecules essential for embryo development.
New studies highlight key differences in stroke risk factors, treatment, and outcomes between men and women. Fluctuations in hormone levels, pregnancy-related complications, and treatment disparities affect women disproportionately.
A study published in Fertility and Sterility found that infertility is significantly associated with a shorter gestation and diminished birth size. Infertile women's infants weighed less, were shorter, and had smaller head circumferences compared to non-infertile women.
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Researchers found that prenatal stress can promote developmental plasticity in babies, making them more likely to benefit from good parenting. However, this effect only manifests when they are reared in supportive environments.
Two studies found that women with MS who stop taking natalizumab before or after pregnancy experience increased disease activity and relapse rates compared to those who continue treatment. The risk of miscarriage is also higher in the first trimester, but this rate is small and within the general population range.
Young adults with highly committed relationships and strong sexual decision-making roles are more likely to use hormonal or long-acting contraceptives. Conversely, those in less committed relationships or who have played a lesser role in contraceptive decisions tend to rely on condoms.
A recent study has estimated the frequency of fetal alcohol spectrum disorders among first-graders in four US communities, finding rates as high as 50 per 1,000 children. The findings suggest a more accurate prevalence estimate than previous studies, but may not be generalizable to all communities.
A randomized trial found that induced labor at 39 weeks significantly reduced cesarean birth rates compared to expectant management. Healthy, first-time mothers who underwent elective induction had lower rates of preeclampsia and respiratory support for their newborns.
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A new study from Washington University School of Medicine found that West Nile and Powassan viruses can cause brain damage and fetal death in mice, similar to Zika. The study suggests that these flaviviruses may also pose a risk to developing fetuses in humans.
A study published in PLOS ONE found that mothers over 40 have an increased risk of preterm birth, even after adjusting for confounding factors. Mothers aged 30-34 years old had the lowest risk of prematurity.
A study reveals that two bacteria can induce cervical changes linked to spontaneous preterm birth, highlighting the potential role of vaginal and cervical bacteria in premature labor.
A study published in the European Journal of Obstetrics & Gynecology and Reproductive Biology reveals that 64% of pregnant women experience insomnia in the third trimester, with symptoms worsening throughout pregnancy. The research highlights the importance of addressing this issue to prevent related health problems.
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More than 2,000 maternal-fetal medicine specialists will present research on preventing postpartum hemorrhage, reducing cesarean births, and treating opioid misuse during pregnancy. The Society for Maternal-Fetal Medicine's annual meeting in Dallas aims to reduce high-risk pregnancy complications and promote public policy advancements.
Researchers found that tranexamic acid prevents blood loss after vaginal births and postpartum hemorrhage among women with operative vaginal deliveries or episiotomies. The study, presented at the Society for Maternal-Fetal Medicine's annual meeting, suggests TXA should be considered for women at risk of PPH.
Experts from obstetric care and addiction medicine meet to discuss the current evidence on substance use disorders (SUD) in pregnancy. They aim to review existing barriers to accessing treatment for SUD in pregnant women and provide clinical guidance for obstetric care providers.
Researchers found that women following a Mediterranean-style diet before IVF had a 65-68% greater likelihood of achieving a successful pregnancy and birth compared to those with the lowest adherence. The study suggests that a healthy diet, such as the Mediterranean diet, may help increase chances of fertility.
A new study found that women with low carbohydrate intake are 30% more likely to have babies with neural tube defects. Folic acid supplementation is crucial for minimizing this risk, as many women may not take a daily multivitamin before and during pregnancy.
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The study aims to evaluate the current preferred first-line regimen for pregnant women recommended by WHO and two newer drug regimens containing dolutegravir. It will provide data on the use of these newer drugs during pregnancy, helping to ensure that women living with HIV and their infants receive the best available treatments.
Spontaneous subarachnoid hemorrhage is a rare type of stroke occurring in 6% of pregnant women, with better outcomes compared to non-pregnant women. Pregnant women with sSAH have lower mortality rates and are more likely to be discharged home.
Research suggests that C-sections are associated with a decreased risk of urinary incontinence and pelvic prolapse, but an increased risk of asthma, obesity, and pregnancy complications. The study analyzed data from over 29 million participants and found mixed results on the long-term effects of C-sections.
A study comparing hysteroscopic and laparoscopic sterilization methods found that hysteroscopic sterilization was associated with a higher risk of gynecological complications, but not with an increased risk of medical outcomes. The study followed 105,357 women in France for one to three years after sterilization.
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Observational research suggests that probiotic intake during late pregnancy may lower the risk of pre-eclampsia and premature birth. A significant association was found between probiotic consumption and a 20% lower risk of pre-eclampsia, while an 11% lower risk was observed for premature birth during early pregnancy.
A recent study published in BMC Medicine suggests that premature births are associated with an imbalance of bacteria in the mother's reproductive tract. The researchers found that subtle changes in vaginal microbiota were strongly linked to early water breakage and preterm birth, which can increase the risk of sepsis for newborns.
Researchers found increased risk of congenital malformations with methimazole and propylthiouracil use during the first trimester. This association confirms the importance of minimizing MMI use in pregnancy and suggests reevaluating the current recommendation to switch from MMI to PTU.
Researchers found that Zika virus infection in pregnant rhesus monkeys caused placental tissues to become thickened and inflamed, leading to decreased oxygen levels and impaired fetal development. The study's findings may provide important insights into preventing Zika virus infection and disease during pregnancy.