Articles tagged with Dermatology
A large-scale genetic study has identified seven genes that increase an individual's susceptibility to leprosy, a chronic infectious disease affecting skin and peripheral nerves. The discovery highlights the role of innate immune response in leprosy development and may lead to early diagnosis and treatment.
A new study found that cancer patients treated with epidermal growth factor receptor inhibitors (EGFRIs) have a high prevalence of skin and nail infections. The researchers discovered that 38% of patients developed these infections, including bacterial infections resistant to common antibiotics.
A new study led by UC Davis Health System dermatologist April Armstrong found that daily text messages reminding people to apply sunscreen increased its use by nearly twice as much as those who did not receive such messages. The study aimed to explore the potential of text messaging to encourage healthy habits in patients, and its find...
Daily text-message reminders significantly increased sunscreen application among participants over a six-week period. The study found that adherence rates were 56.1% with daily reminders compared to 30% without reminders.
Researchers found that aggressive microdermabrasion using a coarse diamond-studded instrument induced molecular changes in the skin of older adults, similar to those seen during wound healing. This procedure mimicked natural skin remodeling processes and increased collagen production.
Since 2000, there has been a dramatic increase in cosmetic and non-cosmetic surgical procedures performed by dermatologic surgeons, with a 120% growth rate between 2001 and 2007. The procedures with the greatest increases were soft tissue augmentation, botulinum toxin injections, and non-ablative skin rejuvenation.
A study found that dermatologists detected 56.3% of all melanomas and 60% of in situ melanomas, compared to 54.5% for patient-detected cases. Dermatologist detection was also associated with thinner melanomas, with median depths of 0.33mm for physician-detected cases versus 0.55mm for patient-detected cases.
A web-based system allowing general practitioners to confer with specialists about skin conditions has been shown to reduce referrals to dermatologists by approximately 20%. The study found that in-person consultations were preventable for 39% of patients who received teledermatologic consultations, compared to 18.3% in the control group.
A Stanford University School of Medicine survey finds that Asian Americans living in California are adopting unhealthy sun-exposure behaviors as they become more westernized. The study highlights the need for increased skin-health awareness among primary care physicians and people of Asian ancestry.
A clinical trial conducted by the University of Manchester found that No7 Protect & Perfect Intense Beauty Serum can clinically reduce wrinkles and improve sun-damaged skin. The study, which tested 60 volunteers, showed a significant improvement in facial wrinkles after 12 months of daily use.
Low-dose acitretin therapy shows promise in reducing nail psoriasis symptoms, with 25-33% of patients experiencing complete or near-complete clearing. The treatment also demonstrates safety and effectiveness in improving quality of life for patients suffering from severe nail psoriasis.
A new study finds that Albolene moisturizing cleanser is as effective as a prescription moisturizer in reducing dryness, scaling, and itching related to mild to moderate eczema. The study suggests that over-the-counter moisturizers can be a cost-effective alternative for treating eczema without a prescription.
A study found that sun-safe pool policies are associated with improved sun safety behaviors among outdoor staff, leading to fewer reported sunburns. The program also promotes healthy sun protection habits and creates a work environment conducive to developing these habits.
A study of 170 military personnel who were evacuated from combat zones found that 34% were diagnosed with dermatitis or general skin inflammation. The study highlights the importance of identifying individuals with chronic skin conditions before deployment to reduce evacuations and improve combat effectiveness.
Scientists have found a genetic variant within the LCE gene cluster that provides protection against psoriasis. This discovery suggests compromised skin barrier function plays a role in the disease's development.
Psoriasis affects 0.6-4.8% of the world's population, impairing financial status and well-being. Online support groups provide valuable resources, anonymity, and improved quality of life for patients. The study found that 49.5% of participants perceived improvements in psoriasis severity since joining an online community.
Patients using a retinoid cream containing tretinoin were more likely to die than those using a placebo in the study. However, evidence does not suggest that the therapy caused the excess deaths, and alternative explanations such as smoking are possible.
A study published in Archives of Dermatology found that light-activated therapy increased levels of Ki67, a protein involved in new skin cell growth, and collagen production. Skin thickness also increased after treatment, suggesting improved appearance.
Researchers found that photodynamic therapy, combining a topical photosensitizer and laser treatment, increases collagen levels and produces other skin changes in sun-damaged skin. The treatment may be particularly effective for skin with severe sun damage.
Research from Michigan Medicine found that estrogen treatments stimulate collagen production in non-sun damaged skin, but have no effect on sun-damaged skin. The study suggests it's difficult to repair photoaged skin due to altered skin response to topical estrogen treatment.
Scientists have pinpointed the FCER1A gene as a major factor in allergic diseases, influencing IgE antibody production and leading to conditions like hay fever and asthma. The discovery has potential for guiding new drug development.
A 21-year-old amateur bodybuilder suffered from anabolic steroid-induced acne conglobata, leading to deep ulcerations and abscesses. Discontinuing steroid use improved skin lesions, but extensive scarring is expected to remain lifelong.
A study of 266 teens with acne found that they would trade significant time and money for freedom from the condition. Teens were willing to pay up to $275 to never have acne, while parents were willing to pay $250 for their child's acne-free life.
A study published in Archives of Dermatology found that women are more likely to remove their tattoos due to social stigma and embarrassment, with 69% of participants being women. The study also revealed that societal support for women with tattoos is limited, leading to increased dissatisfaction with their tattoos over time.
Researchers found that topical retinoic acid, carbon dioxide laser resurfacing, and injections of cross-linked hyaluronic acid improve skin's appearance and resistance to bruising by stimulating new collagen production. Collagen collapse is a key factor in skin aging, but fibroblast cells can recover and make more collagen.
Researchers found that polyalkylimide implants can cause infrequent but sometimes severe immune-related adverse effects, including swelling, hardening, and systemic symptoms, in patients who received these fillers at least 12 months prior.
Regular skin self-exams can help couples detect melanoma earlier, increasing their chances of survival. Couples with strong bonds are more likely to perform these exams and support each other through the process.
Larger skin lesions are more likely to be melanomas than smaller moles, according to a new study by NYU researchers. The study confirms that an important warning sign of melanoma - moles larger than 6 millimeters - is still valid.
A new calcineurin inhibitor ISA247 has been shown to be safe and effective in treating moderate to severe psoriasis. The study found a strong correlation between drug dose and response, allowing for more accurate dosing to minimize side effects.
A study found that melanomas can appear noticeably different from other moles, with 85% of participants identifying them as distinct. The 'ugly duckling' sign may prove a useful screening strategy for primary health care providers and skin self-examination.
A study published in Pediatric Dermatology reveals that infants who developed hemangiomas had lower levels of oxygen in their placentas compared to healthy preterm infants. The research suggests that disturbed placental circulation may have contributed to the development of infantile hemangioma.
A review published in Dermatologic Therapy reveals that men need higher doses of Botox due to greater muscle mass, leading to inadequate results from under-dosing. The study suggests that larger, stronger men require more units per treatment area than slender, small-boned men.
A study published in Journal of Cosmetic Dermatology found that topical application of niacin, engineered peptides, retinoids, and photoprotective ingredients can visibly improve maturing skin. Combining these ingredients in a moisturizer magnifies benefits.
A study published in Dermatologic Therapy reveals that rituximab effectively treats blistering skin diseases, including paraneoplastic pemphigus, by targeting abnormal immune responses. The drug's efficacy is being explored for other serious dermatological disorders, but its indications are still being defined.
A Brazilian study found that a 7 percent caffeine solution cream reduced thigh circumference by over 80% and hip measurements by nearly 68%. However, the effect on cellulite was less clear, with imaging showing little change. The researchers speculate that the trial may not have been long enough for the cream to act on cellulite.
Four distinct skin disorders were found in construction workers who helped repair buildings after Hurricane Katrina and Hurricane Rita. These disorders affected 42.6% of the workers, with papular urticaria being the most common, followed by bacterial folliculitis and fiberglass dermatitis.
A Phase 3 trial found that ustekinumab achieved significant improvements in psoriasis symptoms and quality of life measures, with over two-thirds of patients experiencing at least a 75% reduction in psoriasis symptoms. The treatment resulted in substantial proportions of patients maintaining responses through week 28.
Research found that patients traveling farther to reach their physician are more likely to have thicker skin cancer at diagnosis. Longer distances were associated with increased Breslow thickness, and rural locations and lack of dermatologists in the area also contributed to poorer outcomes.
The disease varies by race, sex, and geographic area, with higher incidence among blacks and men. The nationwide rates of the disease were last documented in 1992.
Non-compliance with dermatologic treatment is a widespread issue, and physicians can improve compliance by establishing strong patient-physician relations, choosing suitable medications, and using effective education materials. Research shows that addressing non-adherence can lead to better success for patients with psoriasis and other...
A 12-year review of skin cancer data in Northern Ireland found that wealthy individuals and older adults are disproportionately affected. The study also shows a significant increase in skin cancer rates, with malignant melanoma being the most common serious form of skin cancer.
Researchers tested retinol-containing lotions on elderly patients, finding significant reductions in wrinkles, roughness, and overall aging severity. The study also showed increased collagen production, making the skin more resistant to injury and ulcer formation.
Researchers assessed the effectiveness of topical retinol lotion in reducing wrinkles and improving skin aging severity. The study found significant reduction in wrinkle formation and increased collagen production, leading to improved appearance and skin resilience.
The American Academy of Dermatology surveyed 32 US metropolitan regions to identify the most and least sun-smart cities. Washington, D.C. and New York City topped the list, while Chicago was ranked as the least sun-smart city due to low knowledge and attitudes towards tanning and sun protection.
A clinical study found that a cream commonly used to treat eczema may be effective in treating oral erosive lichen planus, a severe inflammatory condition. Another study showed limited benefit of pentoxifylline in treating recurrent apthous stomatitis, but the treatment was associated with significant adverse effects.
Research found that individuals with melanoma diagnosed by a dermatologist tend to have thinner tumors, leading to improved five-year survival rates. The study analyzed data from Medicare and cancer databases, comparing outcomes between dermatologist- and non-dermatologist-diagnosed patients.
Researchers found a correlation between smoking and increased fine wrinkling in photo-protected skin, particularly among participants over 65. The study used a novel grading scale to assess the severity of skin aging, which was not previously available for photo-protected areas.
Researchers found a significant link between smoking and skin damage in non-facial areas, such as the inside of the upper arm. Smoking was associated with an increased degree of skin aging, with smokers showing more severe fine wrinkling than nonsmokers.
Researchers at the University of Michigan have discovered that Restylane works by stretching fibroblasts, causing them to create new collagen. This natural collagen then contributes to reducing wrinkle appearance. The study also found that Restylane inhibits the breakdown of existing collagen.
Research by UCSD School of Medicine reveals that Vitamin D3 plays a crucial role in controlling the body's innate immune response and protecting against infections. Fluctuations in vitamin D3 levels affect the healing process of skin wounds, with lower concentrations linked to increased susceptibility to infection.
A study found that learning skin self-examination with a partner enhances the perceived importance and performance of this critical cancer prevention behavior. Participants who learned together showed stronger intentions to examine their skin regularly, especially in hard-to-see areas like the scalp and back.
A recent study published in Dermatologic Surgery reveals a significant link between summer sun exposure and the development of melanoma. Sun protective measures such as sunscreen and clothing are necessary to prevent skin cancer, despite controversy surrounding current guidelines.
Primary care physicians can improve their ability to detect malignant skin lesions using simplified dermoscopy techniques, resulting in a 25% increase in sensitivity. The use of dermoscopy reduces the number of false negatives and improves patient outcomes.
A study found that tanning advertisements appeared in 48% of Colorado high schools' newspapers between 2001 and 2005. The ads often promoted discounts for students or labeled as 'prom specials', but only 13% featured UV-free tanning options.
Researchers used a non-invasive imaging system to detect pigment changes and test the efficacy of topical N-acetyl glucosamine in reducing hyperpigmentation. The study found that N-acetyl glucosamine was more effective than placebo and, when combined with niacinamide, showed significant reductions in facial hyperpigmented spots.
Women who used corrective cosmetics to cover severe facial blemishes reported lower health-related quality of life than those who didn't wear makeup. The study found no difference in quality of life based on the type or size of the blemish, but highlighted the psychological impact of facial marks on self-image and social functioning.
Researchers found that Aldara Cream reduced fine lines and wrinkles, improved skin texture, and enhanced color in prematurely aged skin. The cream showed significant improvements in 80% of the subjects, with 90% expressing strong approval.
Researchers emphasize the need for proactive measures from pediatricians in early childhood to prevent skin cancer. Pediatricians can play a vital role by counseling children and their parents about UV protection, using sunscreen, and wearing protective clothing.
The five-year data demonstrate long-term efficacy and reliability of MAL-PDT for treating superficial and nodular basal cell carcinomas, with superior cosmesis compared to cryotherapy. The treatment was found to be non-inferior to surgery in relation to initial response rates, but with significantly better cosmetic outcomes.
Researchers reviewed 35 patients taking glucocorticoids for chronic skin diseases. The study found that only 20% were taking bisphosphonates, a medication proven to prevent glucocorticoid-induced osteoporosis. The authors recommend prescribing bisphosphonates concomitantly with corticosteroid therapy in certain cases.