Articles tagged with Disease Intervention
A new analysis of chronic limb-threatening ischemia (CLTI) treatment outcomes found that surgical revascularization is superior to endovascular treatment in patients with higher comorbidities. The study analyzed a broader clinical population than the BEST-CLI trial and found similar outcome rates for Medicare beneficiaries.
The next-generation Evolut FX TAVR system shows improved deliverability, tracking, and deployment compared to its predecessor. This is particularly beneficial for patients with difficult anatomies, where the new device's predictable deployment can improve coronary access, blood flow, and valve performance.
A study analyzing European guidelines found that patients with specific characteristics may benefit from longer-term treatment with multiple blood thinners. High-risk patients experienced higher rates of complications due to blood clotting, emphasizing the need for personalized care.
Rodlescia Sneed aims to scale up the Chronic Disease Self-Management Program for older adults in state prisons, analyzing factors that influence effectiveness. She seeks to maximize program use in prisons and determine maximum effectiveness through user manual creation and future R01 grant testing.
A global clinical trial found that bioresorbable vascular scaffolds (BVS) are nearly as safe and effective as conventional metal stents in treating coronary artery disease. The study, led by a researcher from the Mount Sinai Hospital, showed improved outcomes for patients when properly implanted.
The statement highlights enormous inequities in stroke care, leading to significant gaps in functional outcomes for historically disenfranchised groups. Upstream interventions, such as policy changes and place-based initiatives, are crucial to address these disparities.
A mobile app called SCI Step Together encourages people with partial spinal cord injuries to get active by setting goals, tracking activities, and connecting with others. The study found that participants who used the app had greater fulfillment of basic psychological needs, including independence, competence, and belonging.
A new study finds that one-time genomic screening of adults aged 20-60 for hereditary breast and ovarian cancer syndrome, Lynch syndrome, and familial hypercholesterolemia is cost-effective based on quality-adjusted life-year measures. The study suggests that this approach could improve disease management and reduce healthcare costs.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
A Chinese Medical Journal review highlights the health hazards of air pollution, particularly from fine particulate matter (PM2.5), which is associated with increased risks of cardiovascular disease, hospitalization, and respiratory mortality. The study suggests that reducing PM2.5 levels through government interventions and individual...
The International Osteoporosis Foundation (IOF) has awarded five young investigators grants for their research on nutritional factors and musculoskeletal health. The winners' projects focus on various aspects of diet, exercise, and bone health, with potential to lead to clinical advances or preventative strategies.
The program guide for TVT 2023 showcases over 200 world-renowned faculty experts, with a focus on clinical decision-making and strategies for treating valvular heart disease. The summit highlights the latest advances in transcatheter valve therapy and nonsurgical procedures.
A video-based smoking cessation program developed by a University of Massachusetts Amherst researcher has helped nearly 40% of HIV-positive smokers in Nepal quit tobacco. The program, which includes 11 video sessions and is accessible via smartphone app, was found to be highly effective in promoting abstinence among participants.
The American Heart Association scientific statement rates how closely popular dietary patterns align with its guidance for heart-healthy eating. The statement evaluates 10 categories of diets, scoring them from 31 to 100 based on their alignment with the guidance, with some diets receiving high scores while others need improvement.
A systematic review found that physical activity interventions can reduce symptoms and improve outcomes for individuals with substance use disorders. The study examined 26 studies and concluded that physical activity may be an effective adjunct to traditional treatments, reducing or ceasing usage in approximately 75% of cases.
A recent study found that telephone-based health coaching intervention was ineffective in reducing postpartum weight gain among low-income, Latina individuals. Despite this, the intervention was well-received and potentially beneficial for those who spoke English or perceived a high diabetes risk.
A recent study by McGill University found that short exposure to bright light before night shifts can significantly reduce fatigue and errors among nurses. Nurses who received bright light exposure made fewer errors and slept better after their shifts.
Researchers have discovered a link between iron redox and Alzheimer's disease, which could lead to the development of new drugs to treat the condition. The new imaging technique allows for the simultaneous detection of two forms of iron in cells and tissue, providing insights into its role in destroying brain cells.
A global study published in Cochrane Reviews found that consuming cranberry products reduces the risk of repeat symptomatic UTIs in women by more than a quarter. The review also showed benefits for children and people susceptible to UTIs following medical interventions, with minimal side effects reported.
A qualitative case series study provides the first published examples of medication deprescribing protocols for patients with type 2 diabetes. The results highlight the importance of de-escalating glucose-lowering medications when patients achieve remission through lifestyle medicine interventions.
A team of researchers from Indiana University School of Medicine has identified Pyruvate dehydrogenase kinase 4 (PDK4) as a crucial mediator of alcohol-induced liver injury. PDK4 plays a key role in the formation of calcium channels at the ER-mitochondria interface, leading to mitochondrial dysfunction and accumulation of calcium ions.
Researchers found that identifying and targeting 'supercontactors', including nurses and patients with neurological disorders, can significantly reduce the incidence of MRSA colonization. Simulation studies showed that reinforced contact precautions and vaccination targeting these individuals can be more effective than random selection.
Experts recommend managing SARS-CoV-2 like other endemic respiratory viruses using Standard and Transmission-based Precautions. They also suggest reconsidering pandemic-era strategies such as asymptomatic testing and contact tracing in the endemic era.
A new study found that emotion-focused therapy increased activation and connectivity of the amygdala in patients with bipolar disorder, leading to improved emotion processing. In contrast, cognitive-behavioral therapy showed increased activation of brain regions related to social function but not altered amygdala activity.
Dr. Erik K. Paulson, MD, chair of Duke University's radiology department, has been elected as the 123rd President of ARRS for a one-year term starting April 2023. He succeeds Gary J. Whitman, who served from 2022 to 2023.
Researchers used a novel machine-learning technique called causal forest, which found that treating individuals with high estimated benefits provided better population health outcomes than the traditional high-risk approach. This approach targets those with high blood pressure and could lead to more effective treatment strategies.
The NCCN 2023 Annual Conference emphasized the importance of fostering welcoming environments for patients and staff, ensuring care meets latest standards, and rejecting a one-size-fits-all approach. Key findings included the need to address systemic bias, social determinants of health, and staffing issues in cancer care.
A novel clinical trial demonstrated that open-label placebo increased patient retention rates by 78% compared to methadone-only treatment. Participants also reported better sleep quality, with no significant differences found in other outcome measures. The study suggests that deception-free placebo treatment can provide valuable benefits.
The ACC Cardio-oncology Course aims to equip clinicians with the latest strategies and best practices for managing cardiovascular health in cancer patients. The course will feature joint presentations of oncologists and cardiologists, showcasing real-life patient care and collaboration across teams.
Researchers have developed a glycine-based tripeptide that successfully treats nonalcoholic fatty liver disease in non-human primates and mice. The compound, DT-109, reverses fat buildup and prevents scarring by stimulating fatty acid degradation and antioxidant formation.
Researchers found that timed birth strategies, including induced labor and Cesarean deliveries, can reduce the risk of at-term preeclampsia by more than half. The study analyzed over 90,000 pregnancies and suggested that this approach has huge potential for global good in maternity care.
A Rutgers study found that nearly one in five LGBTQ people experienced an increase in intimate partner violence after the COVID-19 pandemic began. Those living in the southern US were more likely to report this increase, with intimate partner violence also linked to greater depressive symptoms.
Partners of colorectal cancer survivors experience long-term financial toxicity leading to worse health-related quality of life. Multilevel interventions are needed to address individual and systemic factors affecting both patients and their partners.
A two-year grant from the Craig H. Neilsen Foundation will support a pilot project implementing Vocational Resource Facilitation to investigate participant and stakeholder experiences. The goal is to enhance return-to-work rates and employment outcomes for individuals with spinal cord injury.
A Brown-led research team found that four dementia-care interventions saved between $2,800 and $13,000 in societal costs and reduced nursing home admissions while improving quality of life. Non-drug interventions have been shown to be effective in clinical trials and can help people with dementia stay safely at home longer.
A new case series study found that an 8-week methylation-supportive diet and lifestyle program reduced biological age by 4.60 years, with five of six participants exhibiting significant age reversal. The study suggests that this intervention may favorably influence biological age in both sexes.
A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...
Researchers found that using monoclonal antibodies within two days of a COVID-19 diagnosis reduced the risk of hospitalization or death by 39% compared to those who did not receive treatment. This finding suggests that early treatment with monoclonal antibodies significantly reduced the severity of COVID-19.
A multi-site randomized controlled trial found Health TAPESTRY to have widespread reach and adoption, but no significant clinical benefits on hospitalizations and physical activity. The study tested implementation and reproducibility of the program across diverse primary care practices.
A cohort study of over 9,000 persons found that asymptomatic middle-aged individuals with subclinical coronary atherosclerosis are at an 8-fold increased risk for myocardial infarction. The study highlights the importance of identifying and addressing obstructive coronary artery disease in patients without known cardiovascular disease.
A study published in Lasers in Surgery and Medicine suggests that light therapy, known as photobiomodulation (PBM), can improve heart function and reduce the thickness of the cardiac wall in middle-aged mice. The research also found improved neuromuscular coordination and a significant survival rate among mice with severe heart disease.
The Lp(a) Discovery Project will develop clinical standards for optimal patient care through a new screening measure and quality improvement interventions. The three-year project aims to fill knowledge gaps around Lp(a) and encourage better treatments to reduce cardiovascular risk.
A recent study published in JAMA Network Open found that food insecurity is associated with a decline in executive function among older adults. The research used data from 3,037 community-dwelling Medicare beneficiaries and suggests that interventions to increase healthy food access may be crucial in mitigating cognitive decline.
A WVU researcher is working on a biopsychosocial intervention to help people with chronic hip pain move and regain mobility. The intervention, called HIPS, combines mindfulness techniques like self-compassion and progressive relaxation with goal-setting and diaphragmatic breathing to reduce pain and increase physical activity.
A recent study found that malaria control programs in Amazonian Peru reduced the disease by 78% but saw a rebound when funding was cut, driven by climate change. Climate change has exacerbated malaria transmission, with rising temperatures and intense rainfalls contributing to the resurgence of the mosquito-borne disease.
A new LSU Health New Orleans study suggests that single, focused Interprofessional Education-based exercises can significantly decrease stigma associated with alcohol use and improve knowledge and confidence in screening for Alcohol Use Disorder (AUD). The exercise led to substantial improvements in student understanding of AUD risks, ...
A metastudy found digital-based physical exercise interventions are at least as effective as face-to-face ones, but generic designs often fail to provide quality information. The researcher aims to improve the digital-health-based prescription of physical exercise to take account of patients' individual requirements.
A study from George Mason University found elevated insulin and hemoglobin A1C levels in early elementary-aged Latino youth with obesity, a risk factor for cardiometabolic diseases. The research aims to identify at-risk children and implement interventions earlier to mitigate the effects of childhood obesity.
An international team of researchers has received $3 million to study how early gut development shapes children's health. They will collect tissue samples from diverse groups to understand the impact of environment, genetics, and other factors on gut development.
A seven-component treatment program, including prompt medical assessment and co-constructing a formulation with the child and family, has been successful in managing FND in children and adolescents. Most healthcare professionals can easily add an FND-informed skill set to their current clinical practice.
A new study by Anglia Ruskin University found that physical activity and pelvic floor exercises can effectively increase latency time in men with premature ejaculation. The research suggests exercise as a promising non-pharmacological treatment option, potentially reducing the reliance on drugs with side effects.
A randomized controlled trial of MOXIE shows a significant reduction in clinical outcomes, including hospitalizations and all-cause mortality. The intervention improved patient engagement and behavior change, leading to better health outcomes for seniors at elevated risk of cardiovascular events.
A virtual care team consisting of physicians and pharmacists improved the adoption of life-saving therapies in patients with heart failure, leading to increased use of evidence-based treatments and better patient outcomes. The strategy was safe and effective, with comparable length of stay and safety events between the groups.
A novel community-focused strategy implemented in Pennsylvania counties led to a 30% reduction in opioid overdose death rates. The approach, developed by University of Pittsburgh researchers, prevented 1,818 opioid-related deaths over two years.
A new study found that military veterans are at higher risk of developing human papillomavirus (HPV)-related cancers due to low vaccination rates. The study suggests that 'catch-up' HPV vaccination campaigns are needed to boost vaccination rates among veterans and reduce deaths from these largely preventable cancers.
Preliminary research found that better sleep health was associated with higher rates of attendance at group interval sessions, adherence to caloric intake goals, and improvement in time spent performing moderate-vigorous physical activity. However, the association between sleep health and physical activity was not statistically signifi...
A study found that time-restricted feeding improves muscle performance in obese fruit flies by upregulating genes related to glycine production and utilization. This approach may provide a natural alternative therapy for managing obesity-related pathologies.
A new screening tool developed by Cleveland Clinic researchers can effectively detect mild cognitive impairment, early Alzheimer's disease, and other related dementias in older adults. The tool has been shown to identify 90% of patients with mild cognitive impairment, offering a potential solution for early detection and prevention.
A new AR system using HoloLens enables doctors to perform transperineal prostate interventions with high accuracy and flexibility. The system provides a 3D immersive experience, allowing doctors to guide needles to their target with ease.
A new review paper from Mayo Clinic outlines how obesity impacts common tests used to diagnose heart disease, such as ECG, CT scan, MRI, and echocardiogram. The study highlights the need for alternative approaches to prevent weight gain in patients with heart disease.