Articles tagged with Disease Intervention
A systematic review of 41 studies involving 7,800 participants found that psychosocial interventions led to decreased healthcare utilization in most services. The greatest reductions were seen among caregivers and individuals with mental illnesses, particularly when interventions were delivered one-on-one by health professionals.
A third of under-fives attending Paediatric Emergency Departments have unmet vaccination need, with tetanus and MMR vaccination coverage levels below target. Researchers call for catch-up campaigns to reach this vulnerable group.
The study found a decreasing trend in the global TBL cancer burden from 1990 to 2019, but regional variations persisted. The burden was highest in upper-middle-income countries and lowest in high-income countries.
Researchers have shed light on the optimal use of intravenous fluids to treat sepsis, a life-threatening condition that affects nearly a third of ICU patients. The review provides critical insights into dosage and timing of fluids to improve treatment outcomes and reduce mortality.
A case series study demonstrated that a whole-food, plant-predominant dietary pattern and standard medical treatment can successfully achieve type 2 diabetes remission in 37 percent of patients. The study contributes novel information on the feasibility of achieving remission simply by eating healthy food.
A new patient-guided intervention using telemedicine has been shown to improve symptoms of fatigue, pain, and depression in dialysis patients. The Technology Assisted Stepped Collaborative Care (TĀCcare) trial found significant improvements in energy levels and pain severity that persisted for six months after treatment.
A systematic review and meta-analysis found that wearable activity trackers improve patient activity, reduce sedentary behavior, and enhance physical function, supporting faster recovery in hospitalized adults. The study examined 15 studies with a combined total of 1911 patients and found significant improvements in clinical outcomes.
A MU study found that providing educational information about naltrexone to healthcare professionals increases patient prescriptions for the drug. The study resulted in a 36% increase in patients leaving the facility with a prescription for naltrexone, suggesting better-informed decisions by healthcare professionals.
A decision analytical model study found that sustained public health interventions can reduce opioid-related overdose deaths. Implementing medications for opioid use disorder and increasing naloxone supply were key factors in reducing death rates.
Researchers have developed an effective treatment that accelerates recovery after stroke by modulating astrocyte reactivity and cortical connectivity. The treatment, which involves administering a molecule called C3a in nasal drops, has shown positive results in mice with stroke, offering new hope for faster and better recovery.
A new study found that combining conventional speech therapy with singing can improve voice problems in individuals with Parkinson's disease. The tele-rehabilitation program showed significant improvements in voice intensity and Voice Handicap Index scores, suggesting a more effective treatment approach.
A new bilingual digital health tool has been shown to significantly reduce binge drinking episodes among Latino emergency department patients. After using the tool, participants experienced sustained reductions in alcohol use over 12 months, compared to standard care.
A new study followed over 7,000 middle-aged and older Canadians for three years, finding that social participation was associated with successful aging. Those who engaged in volunteer work and recreational activities were more likely to maintain excellent health and less likely to develop physical or mental problems.
A randomized clinical trial found that peer health coaching improved mental health-related quality of life in veterans with cardiovascular disease risks. The study suggests a peer-support model integrated into primary care can lead to well-being improvements beyond blood pressure control.
A new study in a mouse model of Alzheimer's disease examines the effects of environmental enrichment on AD symptom progression and pathology. The researchers found that living in an enriched environment improved several measures of metabolism and reduced individual behaviors, which became more similar and rigid as the disease progressed.
A University of Houston study explores why Hispanic individuals experience higher levels of loneliness and its link to hazardous drinking in the US. The research aims to identify predictors of loneliness and provide insights into developing targeted interventions to improve health outcomes among Hispanic communities.
A special issue of the Journal of Pediatric Rehabilitation Medicine explores the treatment and management of cerebral palsy, including spasticity management and pain relief. The articles discuss various approaches to managing spasticity, such as enteral baclofen use and botulinum neurotoxinA injections, aiming to improve care and quali...
A recent study published in GeroScience found that a moderate-protein diet (25% and 35%) improved metabolic health in both young and middle-aged mice. The researchers also observed reduced blood glucose concentrations and lipid levels in liver and plasma. A balanced diet with moderate protein intake may promote metabolic health in huma...
CNIO researchers review the anticancer effects of various diets, including caloric restriction, ketogenic diet, and intermittent fasting. They argue that precision nutrition can be used to treat specific cancers based on tumor metabolism and patient characteristics.
A case study published in the Journal of Alzheimer's Disease reveals that lecanemab can lead to therapy-induced Aβ phagocytosis and multifocal intracerebral hemorrhage, highlighting a potential risk of brain damage and death. The study suggests that better biomarkers are needed to assess the extent of cerebral amyloid angiopathy.
A new randomized, controlled trial aims to integrate nutritional counseling with food-generating activities among people with HIV and food insecurity in the Dominican Republic. The project seeks to reduce viral loads, increase ART adherence, and improve overall health outcomes.
Primary care clinicians reported a range of experiences with telemedicine, from ease of adoption to challenges in conducting physical exams and diagnostic testing. The study also found that telemedicine had both positive and negative impacts on providers and patients, highlighting the need for clear regulations and adequate staffing pr...
A digital gratitude intervention showed initial improvement in well-being among health care workers, with significant gains in positive affect. However, these benefits were largely lost by month three, suggesting a need for sustained interventions to support long-term mental health.
Researchers found that focusing on satiety and satiation through the consumption of fruits and vegetables can lead to better weight loss outcomes. Both diet programs increased levels of satiation and satiety among participants, as well as promoting better quality of life and emotional well-being.
Research published in Children and Youth Services Review found that approximately two-thirds (63%) of adult survivors of childhood physical abuse are in complete mental health. Barriers to achieving this include a lack of social support, chronic pain, and a history of mental illness like depression or substance use disorders.
Researchers tracked immune cell clusters in the aging mouse prostate using highly multiplexed immune profiling. Early adulthood sees myeloid cells, while between 6-12 months old, there's a profound shift to T and B lymphocyte-dominance. The study reveals new insight into prostatic inflammaging and the window for interventions.
A randomized trial found that very low carbohydrate diets led to greater improvements in systolic blood pressure, glycemic control, and weight compared to the DASH diet. The addition of extra support did not have a statistically significant effect on outcomes.
New research highlights the benefits of family-based care for children exposed to early psychosocial deprivation, improving cognitive function, emotional well-being, and social development. The study found that high-quality foster care had a lasting impact on children's brain development and risk of psychopathology.
A study analyzing European guidelines found that patients with specific characteristics may benefit from longer-term treatment with multiple blood thinners. High-risk patients experienced higher rates of complications due to blood clotting, emphasizing the need for personalized care.
A new analysis of chronic limb-threatening ischemia (CLTI) treatment outcomes found that surgical revascularization is superior to endovascular treatment in patients with higher comorbidities. The study analyzed a broader clinical population than the BEST-CLI trial and found similar outcome rates for Medicare beneficiaries.
The next-generation Evolut FX TAVR system shows improved deliverability, tracking, and deployment compared to its predecessor. This is particularly beneficial for patients with difficult anatomies, where the new device's predictable deployment can improve coronary access, blood flow, and valve performance.
Rodlescia Sneed aims to scale up the Chronic Disease Self-Management Program for older adults in state prisons, analyzing factors that influence effectiveness. She seeks to maximize program use in prisons and determine maximum effectiveness through user manual creation and future R01 grant testing.
A global clinical trial found that bioresorbable vascular scaffolds (BVS) are nearly as safe and effective as conventional metal stents in treating coronary artery disease. The study, led by a researcher from the Mount Sinai Hospital, showed improved outcomes for patients when properly implanted.
The statement highlights enormous inequities in stroke care, leading to significant gaps in functional outcomes for historically disenfranchised groups. Upstream interventions, such as policy changes and place-based initiatives, are crucial to address these disparities.
A mobile app called SCI Step Together encourages people with partial spinal cord injuries to get active by setting goals, tracking activities, and connecting with others. The study found that participants who used the app had greater fulfillment of basic psychological needs, including independence, competence, and belonging.
A new study finds that one-time genomic screening of adults aged 20-60 for hereditary breast and ovarian cancer syndrome, Lynch syndrome, and familial hypercholesterolemia is cost-effective based on quality-adjusted life-year measures. The study suggests that this approach could improve disease management and reduce healthcare costs.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
A Chinese Medical Journal review highlights the health hazards of air pollution, particularly from fine particulate matter (PM2.5), which is associated with increased risks of cardiovascular disease, hospitalization, and respiratory mortality. The study suggests that reducing PM2.5 levels through government interventions and individual...
The International Osteoporosis Foundation (IOF) has awarded five young investigators grants for their research on nutritional factors and musculoskeletal health. The winners' projects focus on various aspects of diet, exercise, and bone health, with potential to lead to clinical advances or preventative strategies.
The program guide for TVT 2023 showcases over 200 world-renowned faculty experts, with a focus on clinical decision-making and strategies for treating valvular heart disease. The summit highlights the latest advances in transcatheter valve therapy and nonsurgical procedures.
A video-based smoking cessation program developed by a University of Massachusetts Amherst researcher has helped nearly 40% of HIV-positive smokers in Nepal quit tobacco. The program, which includes 11 video sessions and is accessible via smartphone app, was found to be highly effective in promoting abstinence among participants.
The American Heart Association scientific statement rates how closely popular dietary patterns align with its guidance for heart-healthy eating. The statement evaluates 10 categories of diets, scoring them from 31 to 100 based on their alignment with the guidance, with some diets receiving high scores while others need improvement.
A systematic review found that physical activity interventions can reduce symptoms and improve outcomes for individuals with substance use disorders. The study examined 26 studies and concluded that physical activity may be an effective adjunct to traditional treatments, reducing or ceasing usage in approximately 75% of cases.
A recent study found that telephone-based health coaching intervention was ineffective in reducing postpartum weight gain among low-income, Latina individuals. Despite this, the intervention was well-received and potentially beneficial for those who spoke English or perceived a high diabetes risk.
A recent study by McGill University found that short exposure to bright light before night shifts can significantly reduce fatigue and errors among nurses. Nurses who received bright light exposure made fewer errors and slept better after their shifts.
Researchers have discovered a link between iron redox and Alzheimer's disease, which could lead to the development of new drugs to treat the condition. The new imaging technique allows for the simultaneous detection of two forms of iron in cells and tissue, providing insights into its role in destroying brain cells.
A global study published in Cochrane Reviews found that consuming cranberry products reduces the risk of repeat symptomatic UTIs in women by more than a quarter. The review also showed benefits for children and people susceptible to UTIs following medical interventions, with minimal side effects reported.
A qualitative case series study provides the first published examples of medication deprescribing protocols for patients with type 2 diabetes. The results highlight the importance of de-escalating glucose-lowering medications when patients achieve remission through lifestyle medicine interventions.
A team of researchers from Indiana University School of Medicine has identified Pyruvate dehydrogenase kinase 4 (PDK4) as a crucial mediator of alcohol-induced liver injury. PDK4 plays a key role in the formation of calcium channels at the ER-mitochondria interface, leading to mitochondrial dysfunction and accumulation of calcium ions.
Researchers found that identifying and targeting 'supercontactors', including nurses and patients with neurological disorders, can significantly reduce the incidence of MRSA colonization. Simulation studies showed that reinforced contact precautions and vaccination targeting these individuals can be more effective than random selection.
Experts recommend managing SARS-CoV-2 like other endemic respiratory viruses using Standard and Transmission-based Precautions. They also suggest reconsidering pandemic-era strategies such as asymptomatic testing and contact tracing in the endemic era.
A new study found that emotion-focused therapy increased activation and connectivity of the amygdala in patients with bipolar disorder, leading to improved emotion processing. In contrast, cognitive-behavioral therapy showed increased activation of brain regions related to social function but not altered amygdala activity.
Dr. Erik K. Paulson, MD, chair of Duke University's radiology department, has been elected as the 123rd President of ARRS for a one-year term starting April 2023. He succeeds Gary J. Whitman, who served from 2022 to 2023.
Researchers used a novel machine-learning technique called causal forest, which found that treating individuals with high estimated benefits provided better population health outcomes than the traditional high-risk approach. This approach targets those with high blood pressure and could lead to more effective treatment strategies.
The NCCN 2023 Annual Conference emphasized the importance of fostering welcoming environments for patients and staff, ensuring care meets latest standards, and rejecting a one-size-fits-all approach. Key findings included the need to address systemic bias, social determinants of health, and staffing issues in cancer care.
A novel clinical trial demonstrated that open-label placebo increased patient retention rates by 78% compared to methadone-only treatment. Participants also reported better sleep quality, with no significant differences found in other outcome measures. The study suggests that deception-free placebo treatment can provide valuable benefits.
Researchers found that timed birth strategies, including induced labor and Cesarean deliveries, can reduce the risk of at-term preeclampsia by more than half. The study analyzed over 90,000 pregnancies and suggested that this approach has huge potential for global good in maternity care.
The ACC Cardio-oncology Course aims to equip clinicians with the latest strategies and best practices for managing cardiovascular health in cancer patients. The course will feature joint presentations of oncologists and cardiologists, showcasing real-life patient care and collaboration across teams.
Researchers have developed a glycine-based tripeptide that successfully treats nonalcoholic fatty liver disease in non-human primates and mice. The compound, DT-109, reverses fat buildup and prevents scarring by stimulating fatty acid degradation and antioxidant formation.
A Rutgers study found that nearly one in five LGBTQ people experienced an increase in intimate partner violence after the COVID-19 pandemic began. Those living in the southern US were more likely to report this increase, with intimate partner violence also linked to greater depressive symptoms.