Articles tagged with Disease Intervention
Scientists at the University of Leicester have made a groundbreaking discovery about how cholesterol in our diet is absorbed into our cells. The research, published in Science, highlights the role of two proteins called Aster B and Aster C in transporting cholesterol from the intestine to the bloodstream.
Researchers developed a deep convolutional neural network to pinpoint cardiac catheter tip locations in photoacoustic images, achieving high precision and recall. The approach has the potential to replace fluoroscopy during cardiac interventions, leading to safer procedures.
A four-year blood-pressure intervention significantly reduced the risk of developing dementia among adults with high blood pressure, compared to those who received usual care. The study found that lowering systolic blood pressure to less than 130 mm Hg and diastolic blood pressure to less than 80 mm Hg reduced dementia risk.
The UTHealth Houston Institute for Implementation Science has received a five-year, $5 million grant from the National Cancer Institute to support research and training in implementation science. Researchers will focus on improving cancer control efforts in Mexico and Latin America.
Researchers adapted a COVID-19 collaboration to monitor near-real-time trends in substance use-related hospital and emergency department visits. Detailed data shows large increases in methamphetamine- and opioid-involved hospital and ED visits among Native American, Black, and multiple-race populations.
The Asian malaria mosquito Anopheles stephensi is spreading drug and diagnostic resistant malaria in Africa, increasing the risk of malaria infections by 270%. Its unique ecology and resistance to insecticides make it challenging for conventional mosquito control tools.
The USPSTF concludes that routine screening for dental caries or periodontal-related disease in adults lacks sufficient evidence, potentially leading to unnecessary procedures. Preventive interventions are also not recommended, as the current evidence is insufficient to assess their benefits and harms.
A recent study found that insufficient antibody transfer to newborn beef calves leads to negative health effects, including increased medical treatment needs and mortality rates. Researchers recommend beef calf-specific colostrum intervention strategies and better vaccine management for pregnant cows and heifers.
A study involving UOC researchers confirms that smartphone-based interventions can significantly reduce depression symptoms, especially when combined with professional support. Users prefer simple apps and those with more serious depression use them more.
The USPSTF states that routine screening for oral health conditions, such as dental caries, is not recommended for children and adolescents aged 5-17. Untreated oral health issues can lead to serious infections affecting growth, development, and quality of life.
A clinical study found that a ketogenic diet can improve kidney function in patients with hereditary polycystic kidney disease. After three months, positive changes were seen in key parameters, with no unexpected side effects.
A study of 185 women found that high neighborhood deprivation was associated with changes in DNA methylation and gene expression in Black women with breast cancer. This suggests a potential link between environmental factors and biological susceptibility to chronic diseases.
Researchers found that changing treatment can lead to significant improvement in mobility and quality of life for patients with advanced Parkinson's disease. A nationwide registry is planned to develop scientifically sound guidelines for combination therapies.
Researchers found that patients with elevated NfL levels had a 91% higher risk of worsening disability with relapse within a year, and a 49% higher risk without relapse nearly two years later. The study suggests that interventions may prevent worsening symptoms by targeting nerve cell death.
A novel multicomponent intervention aimed at improving patient access to kidney transplants did not significantly increase the rate of completed steps in a randomized clinical trial involving 20,375 patients. The study highlights the need for sustained efforts to address barriers to transplantation globally.
A large-scale study found that metformin can reduce weight gain and increase adherence to treatment in youth with bipolar disorder. The medication, typically used for Type 2 diabetes, was effective in preventing weight gain and showed promise as a potential solution to this common side effect of SGAs.
A global platform study has released results on the use of simvastatin to treat severely ill patients with COVID-19, showing a high probability of improving outcomes. In contrast, high-dose vitamin C was found to be ineffective and potentially harmful in critically ill patients, suggesting its use should be discontinued.
A study of 5,435 adolescents and young adults with cancer found that those receiving specialty palliative care experienced a decrease in pain severity. However, the intervention did not affect other symptoms, highlighting the need for new interventions targeting other symptoms during treatment.
Postoperative wound infections in the head and neck region are common complications, with risk factors including age, smoking, and comorbidities. Aseptic operating conditions and peri/postoperative antibiotics can help minimize infection rates.
A study by UC Riverside researchers found that communities of color in Inland Southern California experienced fear and mistrust of institutions due to historical, cultural, and social traumas. The study highlights the need for culturally sensitive health interventions to address these traumas and promote community-based approaches for ...
A meta-analysis of 40 studies involving 310,000 youths found low treatment rates for depression and anxiety in children and adolescents. Targeted interventions to improve psychiatric disorder treatment rates are urgently required.
Researchers will study the impact of exercise, intermittent fasting, and their combination on fatigue, biomarkers of inflammation, and quality of life in women with advanced breast cancer. The trial aims to improve treatment tolerability and possibly life duration for these patients.
A new study published in JNCCN found that intensive local-regional treatment to remove as much tumor as possible did not significantly impact overall quality of life for patients with metastatic colorectal cancer. However, the treatment was associated with a higher risk of adverse events.
A UMass Amherst study explores gender differences in HIV-related stigma and social support among people living with HIV experiencing food insecurity in the Dominican Republic. Women described outright rejection, violence, and disempowerment, while men's experiences were more subtle.
A multilevel primary care intervention, including electronic health record reminders and patient outreach, improved timely follow-up of overdue abnormal cancer screening test results for breast, cervical, colorectal, and lung cancer. The intervention was found to be effective in reducing missed screenings.
A large public health survey in rural South Africa found that approximately half of people living with HIV, diabetes or hypertension have unmet health needs. The study's novel framework quantifies met and unmet health needs for individuals living with infectious and non-communicable diseases.
A research team has developed a technology that selectively targets and eliminates aging cells, contributing to various inflammatory conditions. This approach represents a new paradigm for treating age-related diseases with minimal toxicity concerns.
A pharmacist-led intervention has been shown to improve medication adherence among Latinos with type 2 diabetes, leading to significant reductions in blood sugar levels. The study found that patients who interacted with a pharmacist had an average 0.45% reduction in blood sugar, while systolic blood pressure remained unchanged.
The American Heart Association calls for building on existing research and implementing cross-sector approaches to Food Is Medicine. FIM programs aim to improve health outcomes by providing healthy food resources to treat, manage, and prevent specific chronic conditions.
The 'Crystal Ribcage' technology enables scientists to study lung function at a cellular level while maintaining physiological processes. This innovation holds immense potential for understanding lung diseases and developing new treatments.
A Michigan Medicine-led report found that adding a mobile health application to wearable devices did not significantly improve physical activity levels in patients enrolled in cardiac rehabilitation. However, some short-term outcomes showed an increase in walking distance over six minutes for Fitbit users.
A new study from the University of British Columbia suggests that people with multiple sclerosis are nearly twice as likely to experience mental illness before symptoms appear. The research found higher rates of psychiatric conditions in patients with MS compared to the general population.
Researchers found dementia prevalence among people with ID to be 6.44%, with modifiable risk factors identified as hypertension, depression, stroke, age, severity of ID, duration of education, and traumatic brain injury. These findings can inform better screening and support for individuals with intellectual disabilities.
The Intergovernmental Negotiating Body Bureau emphasizes the importance of social media regulation and digital health literacy in managing infodemics, which can spread false information on public health matters. Effective infodemic management is seen as a critical component of the Pandemic Accord to safeguard lives worldwide.
Preeclampsia, a major cause of maternal mortality, has increased by 37% in Texas since 2017. A new $1.47 million NIH grant will support research initiatives to address preeclampsia rates in six Panhandle counties.
A new health care utility model called Civica Rx increases supply security and reduces costs for health systems, with increased access to critical medications. The model prioritizes access over profit and offers transparent pricing for all customers.
A team of researchers at Case Western Reserve University has identified a genetic defect in Caveolin-3 that increases the risk of developing esophageal adenocarcinoma. The discovery could lead to early screening, lifestyle modifications, and targeted treatments for individuals with a family history of the disease.
A study of 194 patients found that those with alcohol-related diagnoses made 44% more visits and had a 138% higher death rate over 20 years compared to controls. Targeted interventions in emergency departments may help reduce this significant health burden.
Researchers found that preschoolers from low-income families had poorer health outcomes and improved less in healthy lifestyle habits compared to their peers from more affluent backgrounds. The intervention program showed significant improvements in knowledge, attitudes, and behaviors among children with higher socioeconomic status, bu...
A study of 2,176 US counties reveals that breast cancer mortality is influenced by local factors such as poverty, education, and access to healthcare. The findings suggest that geographically targeted interventions could lead to healthier communities and reduced mortality rates.
A new study led by Dr. Armen Saghatelyan uncovered the migratory mechanisms of neuronal cells in a neurodevelopmental disorder. The team found that modulating autophagy with FDA-approved drug metformin restored the cells' migratory properties.
Repeated traumatic brain injury contributes to Alzheimer's disease by promoting de novo tau pathogenesis and facilitating pathological tau transmission in mouse models. Axonal microtubule disruption is a key molecular mechanism underlying rTBI-induced protein pathogenesis.
A new study published in the Journal of the American Heart Association found that improvements in socioeconomic status are not equally beneficial for all racial or ethnic groups. Higher socioeconomic status is linked to better heart health, but this link is greatest among white adults compared to people in other groups.
Researchers found that enteroendocrine cells in Drosophila intestinal epithelium undergo dedifferentiation into intestinal stem cells in response to nutritional changes, such as recovery from starvation. This process is vital for ISC expansion and subsequent intestinal growth following food intake.
A study published in JAMA Network Open reveals that childhood survivors of acute respiratory distress syndrome (ARDS) are at high risk of readmission within two months after discharge. The research suggests that targeted interventions such as telephonic contact, follow-up clinics, and home health care may help reduce readmission rates.
A team of clinical psychologists at VCU Massey Cancer Center is implementing a virtual telehealth therapeutic intervention program to treat insomnia among military members, veterans and their family members with brain cancer. Cognitive Behavioral Therapy for Insomnia (CBT-I) will be used as the front-line treatment option.
Research from Boston Medical Center found that providing pragmatic support improved treatment outcomes for people with HIV who inject drugs in St. Petersburg, Russia. The odds of achieving viral load suppression at 12 months were 3 times higher for participants randomized to the intervention group.
A randomized clinical trial of psilocybin treatment found a clinically significant sustained reduction in depressive symptoms and functional disability. The study's findings support the potential of psilocybin as a novel intervention for major depressive disorder when administered with psychological support.
A Michigan Medicine study found that pulmonary embolism death rates remained unchanged over the past decade, with higher mortality rates among men, Black patients, and those from rural areas. The study analyzed over 100,000 deaths related to pulmonary embolism between 2006 and 2019.
Researchers found four main barriers to healthy diets in young female cancer survivors with fertility challenges, including lack of trust in healthcare providers and motivation. To overcome these barriers, nutrition programs should use evidence-based strategies and tools like motivational interviewing and social support.
A new Stanford-led study shows that adding zinc to farmland soil can help prevent childhood stunting, a condition due to chronic undernutrition that is associated with poor brain development and long-lasting harmful consequences. The researchers found that the presence of zinc in soil helps prevent stunted childhood growth.
Researchers are developing a community-based digital health intervention to increase vaccination uptake among children in rural and underserved areas. The project aims to empower community health workers to deliver education on vaccinations, overcoming the digital divide and addressing challenges faced by limited health workforce.
The Cardiovascular Research Foundation has announced the TCT 2023 late-breaking clinical trials, featuring 12 studies on minimally invasive techniques, pharmaceuticals, technologies, and devices. These trials aim to improve patient outcomes in cardiovascular disease, with a focus on safety and effectiveness.
A study by Texas A&M University found that pregaming is linked to unsafe alcohol use and other risky behaviors among college students. Pregaming was associated with a two-day increase in alcohol use frequency and was found to be around 2.5 times more likely to lead to cannabis or other drug use.
A new study found that voluntary collective isolation alone was ineffective in preventing the spread of COVID-19 among the Amazonian Tsimané. The researchers used a computer model and serological testing to confirm their predictions, showing nearly identical infection rates across communities.
The study found that black soldier fly larvae oil exhibits anti-inflammatory properties, suppressing proinflammatory cytokines and improving colon health. BSFL oil's unique compound profile may offer a new approach to managing inflammatory diseases.
Scientists have identified platelet factor 4 (PF4) as a common messenger for the cognitive benefits of young blood transfusion, exercise, and the longevity hormone klotho. Studies show that PF4 calms down the aged immune system, reducing inflammation and promoting brain plasticity and cognition.
Most U.S. infants requiring intensive care for RSV lower respiratory tract infections were young and healthy, born at term. RSV preventive measures targeting all infants are urgently needed to reduce severe illness burden.
A new study found that intensive lifestyle intervention, including weekly counseling on diet and exercise, is associated with increased employment among people with type 2 diabetes. Study participants without a college degree had even larger employment gains from lifestyle changes recommended by specialists.
An intensive lifestyle intervention was associated with increased employment rates and improved labor market outcomes. The study suggests that such interventions can positively impact individuals with type 2 diabetes, highlighting the importance of considering labor market productivity in disease management.