Articles tagged with Risk Factors
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study by Harvard T.H. Chan School of Public Health researchers found a strong association between Epstein-Barr virus infection and multiple sclerosis. The risk of MS increased 32-fold after EBV infection, while serum levels of neurofilament light chain, a biomarker of nerve degeneration, only increased after EBV infection.
A pioneering test called AMBLor has been developed to predict the spread or return of skin cancer. By analyzing primary tumor biopsies, the test identifies patients at low risk of disease progression, providing them with more accurate information and personalized prognosis.
A study suggests that nearly 60 percent of the risk associated with coronary artery disease may be explained by changes in hundreds of genes working together in networks across several organs. Fat processing hormones may play a central role in coordinating this activity.
Researchers estimated severe SARS-CoV-2 outcomes in youths tested positive in emergency departments, highlighting key risk factors. The study found higher risks of severe illness among younger patients with underlying health conditions.
A study identified factors at midlife associated with a decline in women's physical health 10 years later. Higher body mass index, smoking, osteoarthritis, and depressive symptoms were found to be significantly linked to clinically important declines in physical health.
A new study reveals that Indigenous communities in Canada are more vulnerable to flood-related hardship due to pre-existing socioeconomic factors. The research highlights the importance of considering social vulnerability when assessing flood risk in these communities.
The number of adults living with dementia worldwide is expected to nearly triple from an estimated 57 million in 2019 to 153 million in 2050 due to population growth and aging. Improvements in global education access are projected to reduce dementia prevalence, but obesity, high blood sugar, and smoking are expected to increase cases.
Researchers at Boston Medical Center created a new resource to manage long-term heart disease risk after specific pregnancy complications. The review synthesizes recommendations for primary care clinicians to assess and manage risk, focusing on preeclampsia, gestational diabetes, and preterm delivery.
A new study suggests that midlife cardiovascular conditions and risk factors were associated with midlife cognitive decline, but the association is stronger for women. Certain cardiovascular conditions, such as diabetes and heart disease, had stronger associations with cognitive decline in women compared to men.
A study of temperature and mortality in Pune found that cold causes more deaths than heat, challenging authorities' focus on heatwaves. The research suggests that public health strategies should reflect this finding to better prepare for extreme weather events.
A Colorado State University study analyzed global health data to identify the leading causes of deaths and disabilities in the state from 1990 to 2019. Cardiovascular disease and cancers accounted for half of the deaths, while musculoskeletal disorders and tobacco use were also significant contributors.
A study of over 6,000 women found that US-born Black women are at higher risk of preeclampsia, but this is not solely due to their racial background. Factors such as biology, social and cultural elements, and access to healthcare also play a role in this disparity.
A study of nearly 12,000 obese patients found that substantial weight loss achieved through weight loss surgery was associated with improved outcomes after contracting COVID-19, including lower risk of severe disease. The results suggest that weight loss surgery may help mitigate the severity of COVID-19 in individuals with obesity.
A study at the University of Helsinki found that the APOE4 allele may increase cerebral microhaemorrhages and mental fatigue in COVID-19 patients. The risk of developing severe COVID-19 more than doubled in carriers of this allele.
A recent study published by Queen Mary University of London has found that certain risk factors for heart disease are linked to changes in the structure and appearance of the heart. The research analyzed images from over 30,000 people's heart MRI scans using a new imaging toolkit called radiomics.
Researchers analyzed the largest cross-species database to assess species-specific cancer mortality rates and found conclusive proof that cancer risk is largely independent of body mass and life expectancy. The study highlights potent mechanisms of cancer resistance in larger species, contradicting intuitive expectations.
A new Northwestern University study has derived and validated the first set of risk prediction models for lifetime risk of heart failure. The models can identify individuals at greatest risk, especially among young adults, allowing physicians to start prevention measures sooner.
A new post-surgery approach for treating HPV-related throat cancer uses low-dose radiation and spares the majority of patients from chemotherapy. The trial found high survival rates and quality of life in patients at medium risk for recurrence.
Researchers found that for 20% of risk factor combinations, Black-white differences in predicted risk can result in different treatment decisions. They also observed large differences in predicted risk, with Blacks being prescribed statins more often due to perceived higher risk.
A large-scale new study found that frailty was a strong risk factor for dementia, even among people at high genetic risk, and that it can be modified through a healthy lifestyle. Over 10 years, dementia was detected in 1,762 participants, with those who were frail before diagnosis having a much higher risk.
Exposure to nitrogen dioxide and fine particles is associated with increased beta-amyloid protein deposition and neurofilament light in cerebrospinal fluid, indicating a potential risk factor for Alzheimer's disease. The study highlights the importance of reducing exposure to air pollution to mitigate this risk.
Scientists at Kumamoto University have developed a novel peptide vaccine that improves obesity-related dyslipidemia and may be cost-effective. The vaccine targets angiopoietin-like protein 3 (ANGPTL3) and has been shown to reduce dyslipidemia in mice, producing antibodies that last for six months.
A study published in CMAJ found that hospital health care workers in Quebec had high seroprevalence of SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic. The highest rates were reported in hospitals with outbreaks, particularly those from older facilities.
Hospitalized COVID-19 patients with chronic exposure to higher particulate matter had increased risks for ICU admission and death. Chronic air pollution exposure was associated with an 11% higher risk of mortality and a 13% higher risk of ICU admission.
A study by University of New South Wales has found that one in five future thyroid cancers in Australia is attributable to current levels of overweight and obesity. The prevalence of obesity has doubled in the last two decades, with 75% of Australian men and 60% of women being overweight or obese.
Researchers at the University of Missouri have developed a free online resource that speeds up data analysis of human genomes three times faster than current methods. This enables scientists to see how an individual's genome makes them susceptible to different diseases in different ways, ultimately reducing associated costs and increas...
A study found that obesity is associated with severe COVID-19 outcomes, including hospital admission or death. Additionally, accelerated immunosenescence may be a key mechanism explaining the relationship between obesity and T2DM in severe COVID-19. Vaccination effectiveness may also be impacted by metabolic disorders.
Children with autism spectrum disorder should be screened for abnormally high or low cholesterol levels, according to physicians. Research found reduced HDL-C levels in individuals with ASD, indicating a risk factor for cardiovascular disease.
Researchers developed an AI program that accurately identified patients at risk of serious illness due to blood infections, with an accuracy rate of 82%. The technology has the potential to serve as an early warning system for doctors, enabling them to rank patients based on their risk level.
A UConn study found that supporting surviving parents can reduce youth suicide risk by combating negative self-views in bereaved children. The Family Bereavement Program improved parenting skills and needs, leading to reduced aversive self-views and increased child positive connectedness.
A daily dose of yoghurt has been found to be associated with lower blood pressure in individuals with hypertension. The study, conducted on 915 community-dwelling adults, found that even small amounts of yoghurt were linked to significant reductions in blood pressure.
Researchers found that urinary incontinence can distract from balance and stability, increasing the risk of falling in older adults. The study showed that the feeling of having to pee acts as a distracting factor, leading to changes in gait patterns similar to those caused by other distracting tasks.
Researchers analyzed TB and COVID-19 patients in California, finding shared sociodemographic characteristics and medical risk factors. The study highlights the importance of addressing these factors to improve health outcomes for both conditions.
A small clinical trial found that eating during the nighttime increased glucose levels, while restricting meals to the daytime prevented this effect. The study suggests that better alignment between internal and external circadian rhythms may drive these benefits.
A study at Karolinska Institutet found that individuals with a resting heart rate of 80 beats per minute or higher had a 55% higher risk of dementia. The association remained significant after adjusting for other cardiovascular diseases, suggesting a potential link between elevated heart rate and cognitive decline.
A recent review reveals alarming increase in physician burnout among diagnostic radiologists, with causes including lack of control, social isolation and technological demands. Possible solutions include heightened engagement, dedicated reading room assistants and mindfulness techniques.
Researchers found that increased physical activity reduced mortality risk in all groups, but health benefits plateaued in healthy individuals and those with cardiovascular risk factors. In contrast, cardiovascular disease patients showed no further benefit beyond a certain volume of physical activity.
A new study from Karolinska Institutet and the University of Helsinki reveals how integrating digital tools, classical laboratory tests, and biomolecular measurements can enable individualized disease prevention. The researchers also found significant correlations between health risks and molecular factors associated with overweight, d...
A new American Heart Association scientific statement highlights how major life events, such as starting school or entering retirement, can negatively impact physical activity levels and heart health. The statement emphasizes the need for proactive measures to address this issue and provides guidance for healthcare professionals to pro...
Masks designed for singers block aerosols, diluting virus-causing particles, while affecting high frequencies. Singer's masks reduced high-frequency power by less than two times, improving enunciation.
A new study by Vanderbilt University has developed Exo-LiFFT, an interactive calculator that helps companies reduce injury risk from work-related musculoskeletal disorders. The tool projects a 20-60% reduction in workplace back injuries for material handling tasks.
A new study finds that schools with high levels of student substance use and depressed feelings have a higher prevalence of discipline, out-of-school suspensions, and police contact. Schools with lower levels of safety and support also experience higher discipline rates.
A study conducted at the University of Jyväskylä found that physically active lifestyle mitigates unfavourable changes in metabolic health during menopause. Menopausal transition is associated with increased abdominal fat mass, blood pressure, and blood glucose levels.
A systematic literature review found HIV seroprevalence in five key populations: men who have sex with men (MSM), people who inject drugs (PWID), prisoners, sex workers, and transgender people. The review identified significant gaps in data, particularly for transgender individuals.
A long-term study has revealed that drinking higher amounts of coffee may make you less likely to develop Alzheimer’s disease. The study found an association between coffee and several important markers related to Alzheimer’s disease, including executive function and amyloid protein accumulation in the brain.
A new study from the University of Eastern Finland found that patients with type 2 diabetes often do not receive adequate cholesterol-lowering treatment, despite guidelines recommending statin prescriptions for elevated LDL-C levels. Women tend to have higher average LDL-C levels and receive less statin treatment than men.
A study using anonymized health data found that people with poorly managed long-term glycemic control are nearly 50% more likely to require ICU treatment if they contract COVID-19. Metformin, insulin, and corticosteroids may also reduce the risk of severe COVID-19.
A University at Buffalo study explores how social and economic characteristics influence hospital readmissions and health inequity in the US. The research found that patients with lower household income, male gender, or treated in urban hospitals have a higher risk of being readmitted within a month of discharge.
A nationwide observational study published in Circulation found that lower levels of income and education are associated with reduced chances of survival after out-of-hospital cardiac arrest. The study analyzed data from 31,373 cases of OHCA between 2010 and 2017, showing a correlation that was observed in both men and women.
Extreme heat events are associated with a greater risk of death from ischemic heart disease, stroke, and heart failure. Preventive strategies aim to reduce hyperthermia and dehydration to minimize cardiovascular risk during extreme heat events.
A new study found that children with persistent, distressing PLEs show impaired cognition, higher levels of psychopathology, and delayed developmental milestone achievement compared to those without these experiences. The researchers highlight the need for early intervention and support for youth who report these experiences.
A study of nearly 500,000 Medicare patients with long-term dialysis revealed COVID-19 risk factors and associated mortality rates. The research highlights the need for targeted interventions to protect vulnerable populations.
A UC study found that Ohioans consider various factors beyond distance and cost when selecting an abortion clinic, including personal experiences, online reviews, and clinic type. The research highlights the importance of social myths and risk perception in shaping choices about abortion care.
Researchers found that cerebral palsy patients with low muscle mass often have inaccurately calculated kidney function, leading to missed diagnoses of advanced kidney disease. This association increases the risk of cardiovascular disease and mortality in this population.
A recent study published in Hypertension suggests that adolescent arterial stiffness may increase the risk of systolic and diastolic hypertension by 20% and 2-fold, respectively, seven years later. Higher arterial stiffness levels were also associated with an increased risk of abdominal and whole-body obesity.
A two-year follow-up of participants found that those who had both their mitral valve and tricuspid valve repaired at the same time experienced better outcomes, including less progression to moderate or severe leakage. This study provides high-level evidence for surgeons on how to perform tricuspid valve repair in these patients.
Researchers have found two genetic risk variants that may exacerbate the severity of sepsis and COVID-19 in African Americans, who carry nearly 40% of these variants. The study identifies potential pathways to reduce health disparities driven by these gene mutations.
Researchers at the University of Kent identified strong evidence-based benefits of preimplantation genetic testing for aneuploidy (PGT-A) in IVF. Live birth rates per embryo transferred and per treatment cycle were significantly higher with PGT-A compared to regular IVF, especially in women over 40.
A new risk score developed by Mount Sinai researchers can help predict possible contrast-associated acute kidney injury among patients undergoing PCI. The 'Mehran-2 CA-AKI Risk Score' enhances management of high-risk patients before, during, and after the procedure.
Women with breast cancer are at a higher risk of developing atrial fibrillation and dying from heart-related issues within the first year. The condition was more common in women who did not receive surgery or radiation as their initial treatment.