Articles tagged with Risk Factors
A groundbreaking genome-wide association study identified 123 genetic regions linked to migraine risk, including two specific genes targeted by recently developed drugs. The study provides insight into the biological basis of migraine and its subtypes, paving the way for new treatments.
A UMass Amherst study found associations between oral contraceptive use and certain tubal ligation methods with lower levels of antimüllerian hormone (AMH), a biomarker for ovarian aging. This may suggest an increased risk for early menopause in women who have used oral contraceptives or undergone specific types of tubal ligation.
A study by Pennington Biomedical Research Center found that black residents in Baton Rouge and New Orleans faced a twice-higher risk of SARS-CoV-2 infection than white residents. Communities with high household crowding, lower income, and disparities in education were also at higher risk.
A strong association exists between COVID-19 deaths and obesity in Black, South Asian, and other ethnic minority groups. The risk of death increases with BMI levels, highlighting the need for tailored plans to protect these individuals.
The ACC cardiooncology course is designed to educate clinicians on improving awareness, identification, monitoring, and management of cardiovascular diseases in cancer patients. The course aims to help clinicians minimize cardiotoxicity from cancer therapies, leading to improved overall survival and quality of life for oncology patients.
A recent study found an increase in intentional drug overdose deaths among young people aged 15-24, older adults aged 75-84, and non-Hispanic Black women. Despite a downward trend in overall deaths, these subgroups saw a rise in intentional overdose death rates, with women ages 45 to 64 having the highest rates.
A new study finds that weight loss is associated with a 46% reduced risk of developing colorectal adenoma. Adults who are initially overweight or obese may be able to reduce their risk by losing weight, while weight gain increases the chance of developing adenoma.
Researchers found that adhering to Life's Simple 7 guidelines significantly lowers the risk of coronary heart disease regardless of genetic predisposition. Individuals with high polygenic risk saw the greatest benefits from a healthy lifestyle, with a reduced lifetime risk and extended years lived free of coronary heart disease.
A national survey of over 2,000 adults aged 50-80 found that most support steps to reduce firearm injury risk, including safety counseling and background checks. The study highlights opportunities to help older adults recognize and address risks in their homes, particularly for those living with children or experiencing cognitive decline.
A new study found that patients with chronic non-communicable diseases are more than twice as likely to die from any cause if they also have a psychiatric comorbidity. Comorbid psychiatric disorders were associated with higher all-cause mortality rates, ranging from 5.5-21.1%.
Researchers found that Asian American individuals are at higher risk for skin cancer due to genetic predisposition and environmental factors. The study emphasizes the need for targeted screening among this population to prevent skin cancer deaths.
Common chronic conditions like high cholesterol, pulmonary diseases, and anxiety disorders saw significant declines in new diagnoses during the COVID-19 pandemic. A substantial increase in primary care physicians, face-to-face visits, and proactive care is needed to address this decline and prevent poor health outcomes.
Researchers at University of Illinois Chicago identified changes in the gut microbiome that can lead to gestational diabetes. They found a specific metabolite, kynurenine, that is increased during pregnancy and contributes to insulin resistance.
A new meta-analysis of available literature on ALS disease has identified a group of seven environmental chemicals as correlates with increased risk of developing ALS. Exposure to these chemicals, including BMAA and heavy metals, may be contributing to the disease burden in certain regions.
Researchers analyzed DNA sequences and electronic health records of thousands of individuals to discover that the chance a pathogenic genetic variant may cause a disease is relatively low, about 7 percent. However, some variants are linked to wide range of risks for disease.
The USPSTF recommends against screening for atrial fibrillation in asymptomatic adults aged 50 or older. The current evidence is insufficient to assess the balance of benefits and harms of screening, which is associated with a substantial increase in stroke risk. Atrial fibrillation is a major risk factor for ischemic stroke.
Researchers at MU developed a new framework to identify people previously overlooked for AUD, focusing on 13 risk factors such as impulsive behavior and reward sensitivity. The framework aims to provide more accurate diagnoses and connect individuals with tailored treatment options.
Middle-aged men with high levels of anxiety and worry are at greater biological risk for developing heart disease and type 2 diabetes as they age. The study found that cardiometabolic disease risk increased with age, regardless of anxiety levels, but anxious individuals were more likely to develop the condition over time.
The Nutrition for Precision Health study will use data from 10,000 participants to develop algorithms predicting individual responses to food and dietary routines. The goal is to create more personalized nutrition recommendations and reduce health disparities.
A Rice University study analyzing COVID-19 death data found that Black and Hispanic communities experienced a disproportionately high fraction of losses from COVID-19 mortality. The study also examined the relationship between air pollution and COVID-19 deaths, but found no statistically significant correlations at a countywide level.
Researchers discovered distinct gut microbiomes in Black and white US women, with potential associations to insulin resistance. The study highlights the importance of understanding individual microbiome variations in relation to metabolic health.
A new study of UK Biobank adults found significantly increased rates of nearsightedness, particularly in children. The study suggests changing environmental factors and gene-environment interactions may be to blame for the rising trend.
A study published in the European Journal of Preventive Cardiology found that prolonged TV watching is associated with a higher risk of blood clots, including pulmonary embolism and deep vein thrombosis. To reduce this risk, scientists recommend taking breaks every 30 minutes to stand and stretch or using a stationary bike.
Researchers found that Rivaroxaban reduces atherosclerosis progression by inhibiting factor Xa-PAR2 mediated macrophage autophagy and inflammasome activity. The study suggests RIV as a potential anti-atherosclerotic drug, offering hope for treating this fatal disease.
Researchers found that adolescent arterial stiffness may be a causal risk factor for hyperinsulinaemia and insulin resistance in young adulthood. Arterial stiffness also temporally precedes low HDL-cholesterol in young adults, with a positive association with triglyceride levels.
A new machine learning model, RefMap, has identified 690 genetic risk factors for motor neurone disease, a five-fold increase from previous estimates. This discovery could lead to the development of new treatments and personalized medicine for patients with MND.
A ketogenic diet has been shown to improve spatial memory and visual memory, lower brain inflammation indices, and cause less neuronal death in individuals with traumatic brain injuries. The diet may also slow down the rate of cellular aging, offering hope for those suffering from this condition.
Researchers at Karolinska Institutet have identified a specific gene variant that protects against severe COVID-19 infection, found in individuals of African ancestry. The study analyzed 2,787 hospitalized patients and 130,997 people from six cohort studies, revealing an 80% prevalence of the protective variant among Africans.
A study by Harvard T.H. Chan School of Public Health researchers found a strong association between Epstein-Barr virus infection and multiple sclerosis. The risk of MS increased 32-fold after EBV infection, while serum levels of neurofilament light chain, a biomarker of nerve degeneration, only increased after EBV infection.
A pioneering test called AMBLor has been developed to predict the spread or return of skin cancer. By analyzing primary tumor biopsies, the test identifies patients at low risk of disease progression, providing them with more accurate information and personalized prognosis.
A study suggests that nearly 60 percent of the risk associated with coronary artery disease may be explained by changes in hundreds of genes working together in networks across several organs. Fat processing hormones may play a central role in coordinating this activity.
Researchers estimated severe SARS-CoV-2 outcomes in youths tested positive in emergency departments, highlighting key risk factors. The study found higher risks of severe illness among younger patients with underlying health conditions.
A study identified factors at midlife associated with a decline in women's physical health 10 years later. Higher body mass index, smoking, osteoarthritis, and depressive symptoms were found to be significantly linked to clinically important declines in physical health.
A new study reveals that Indigenous communities in Canada are more vulnerable to flood-related hardship due to pre-existing socioeconomic factors. The research highlights the importance of considering social vulnerability when assessing flood risk in these communities.
The number of adults living with dementia worldwide is expected to nearly triple from an estimated 57 million in 2019 to 153 million in 2050 due to population growth and aging. Improvements in global education access are projected to reduce dementia prevalence, but obesity, high blood sugar, and smoking are expected to increase cases.
Researchers at Boston Medical Center created a new resource to manage long-term heart disease risk after specific pregnancy complications. The review synthesizes recommendations for primary care clinicians to assess and manage risk, focusing on preeclampsia, gestational diabetes, and preterm delivery.
A new study suggests that midlife cardiovascular conditions and risk factors were associated with midlife cognitive decline, but the association is stronger for women. Certain cardiovascular conditions, such as diabetes and heart disease, had stronger associations with cognitive decline in women compared to men.
A study of temperature and mortality in Pune found that cold causes more deaths than heat, challenging authorities' focus on heatwaves. The research suggests that public health strategies should reflect this finding to better prepare for extreme weather events.
A Colorado State University study analyzed global health data to identify the leading causes of deaths and disabilities in the state from 1990 to 2019. Cardiovascular disease and cancers accounted for half of the deaths, while musculoskeletal disorders and tobacco use were also significant contributors.
A study of over 6,000 women found that US-born Black women are at higher risk of preeclampsia, but this is not solely due to their racial background. Factors such as biology, social and cultural elements, and access to healthcare also play a role in this disparity.
A study of nearly 12,000 obese patients found that substantial weight loss achieved through weight loss surgery was associated with improved outcomes after contracting COVID-19, including lower risk of severe disease. The results suggest that weight loss surgery may help mitigate the severity of COVID-19 in individuals with obesity.
A study at the University of Helsinki found that the APOE4 allele may increase cerebral microhaemorrhages and mental fatigue in COVID-19 patients. The risk of developing severe COVID-19 more than doubled in carriers of this allele.
A recent study published by Queen Mary University of London has found that certain risk factors for heart disease are linked to changes in the structure and appearance of the heart. The research analyzed images from over 30,000 people's heart MRI scans using a new imaging toolkit called radiomics.
Researchers analyzed the largest cross-species database to assess species-specific cancer mortality rates and found conclusive proof that cancer risk is largely independent of body mass and life expectancy. The study highlights potent mechanisms of cancer resistance in larger species, contradicting intuitive expectations.
A new Northwestern University study has derived and validated the first set of risk prediction models for lifetime risk of heart failure. The models can identify individuals at greatest risk, especially among young adults, allowing physicians to start prevention measures sooner.
A new post-surgery approach for treating HPV-related throat cancer uses low-dose radiation and spares the majority of patients from chemotherapy. The trial found high survival rates and quality of life in patients at medium risk for recurrence.
Researchers found that for 20% of risk factor combinations, Black-white differences in predicted risk can result in different treatment decisions. They also observed large differences in predicted risk, with Blacks being prescribed statins more often due to perceived higher risk.
A large-scale new study found that frailty was a strong risk factor for dementia, even among people at high genetic risk, and that it can be modified through a healthy lifestyle. Over 10 years, dementia was detected in 1,762 participants, with those who were frail before diagnosis having a much higher risk.
Exposure to nitrogen dioxide and fine particles is associated with increased beta-amyloid protein deposition and neurofilament light in cerebrospinal fluid, indicating a potential risk factor for Alzheimer's disease. The study highlights the importance of reducing exposure to air pollution to mitigate this risk.
Scientists at Kumamoto University have developed a novel peptide vaccine that improves obesity-related dyslipidemia and may be cost-effective. The vaccine targets angiopoietin-like protein 3 (ANGPTL3) and has been shown to reduce dyslipidemia in mice, producing antibodies that last for six months.
A study published in CMAJ found that hospital health care workers in Quebec had high seroprevalence of SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic. The highest rates were reported in hospitals with outbreaks, particularly those from older facilities.
Hospitalized COVID-19 patients with chronic exposure to higher particulate matter had increased risks for ICU admission and death. Chronic air pollution exposure was associated with an 11% higher risk of mortality and a 13% higher risk of ICU admission.
A study by University of New South Wales has found that one in five future thyroid cancers in Australia is attributable to current levels of overweight and obesity. The prevalence of obesity has doubled in the last two decades, with 75% of Australian men and 60% of women being overweight or obese.
Researchers at the University of Missouri have developed a free online resource that speeds up data analysis of human genomes three times faster than current methods. This enables scientists to see how an individual's genome makes them susceptible to different diseases in different ways, ultimately reducing associated costs and increas...
A study found that obesity is associated with severe COVID-19 outcomes, including hospital admission or death. Additionally, accelerated immunosenescence may be a key mechanism explaining the relationship between obesity and T2DM in severe COVID-19. Vaccination effectiveness may also be impacted by metabolic disorders.
Children with autism spectrum disorder should be screened for abnormally high or low cholesterol levels, according to physicians. Research found reduced HDL-C levels in individuals with ASD, indicating a risk factor for cardiovascular disease.
Researchers developed an AI program that accurately identified patients at risk of serious illness due to blood infections, with an accuracy rate of 82%. The technology has the potential to serve as an early warning system for doctors, enabling them to rank patients based on their risk level.
A UConn study found that supporting surviving parents can reduce youth suicide risk by combating negative self-views in bereaved children. The Family Bereavement Program improved parenting skills and needs, leading to reduced aversive self-views and increased child positive connectedness.
A daily dose of yoghurt has been found to be associated with lower blood pressure in individuals with hypertension. The study, conducted on 915 community-dwelling adults, found that even small amounts of yoghurt were linked to significant reductions in blood pressure.
Researchers found that urinary incontinence can distract from balance and stability, increasing the risk of falling in older adults. The study showed that the feeling of having to pee acts as a distracting factor, leading to changes in gait patterns similar to those caused by other distracting tasks.